Alteration of apoptotic signaling molecules as a function of time after radiation in human neuroblastoma cells

Molecular and Cellular Biochemistry

Volumn 310, Issue 1-2, 2008, Pages 167-179

  Aravindan, Natarajan ^a   Madhusoodhanan, Rakhesh ^a   Natarajan, Mohan ^b   Herman, Terence S ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

Apoptosis; Gene expression; Neuroblastoma; Radioresistance; SK N MC cells

Indexed keywords

COMPLEMENTARY DNA; DEOXYRIBONUCLEOTIDE; DNA FRAGMENT; FLUORESCEIN DERIVATIVE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TETRAZOLIUM;

APOPTOSIS; ARTICLE; CELL LABELING; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DNA MICROARRAY; EARLY RESPONSE GENE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; INCUBATION TIME; LINEAR ENERGY TRANSFER; NEUROBLASTOMA CELL; POLYMERASE CHAIN REACTION; RADIATION DOSE; RADIATION EXPOSURE; RADIOSENSITIVITY; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL LINE, TUMOR; DNA FRAGMENTATION; DNA, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LINEAR ENERGY TRANSFER; NEOPLASM PROTEINS; NEUROBLASTOMA; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BINDING; RADIATION; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 39949083227     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-007-9678-0     Document Type: Article

References (67)

1. Bernstein ML, Leclerc JM, Bunin G, Brisson L et al (1992) A population-based study of neuroblastoma incidence, survival, and mortality in North America. J Clin Oncol 10:323-329
2. Haas-Kogan DA, Swift PS, Selch M et al (2003) Impact of radiotherapy for high-risk neuroblastoma: A Children's Cancer Group study. Int J Radiat Oncol Biol Phys 56:28-39
3. Ikeda H, August CS, Goldwein JW et al (1992) Sites of relapse in patients with neuroblastoma following bone marrow transplantation in relation to preparatory "debulking" treatments. J Pediatr Surg 27:1438-1441
4. Lonergan GJ, Schwab CM, Suarez ES, Carlson CL (2002) Neuroblastoma, ganglio neuroblastoma, and ganglioneuroma: Radiologic-pathologic correlation. Radiographics 22:911-934
5. Ladenstein R, Lasset C, Hartmann O et al (1993) Impact of megatherapy on survival after relapse from stage 4 neuroblastoma in patients over 1 year of age at diagnosis: A report from the European Group for Bone Marrow Transplantation. J Clin Oncol 11:2330-2341
6. Kushner BH, Wolden S, LaQuaglia MP et al (2001) Hyperfractionated low-dose radiotherapy for high-risk neuroblastoma after intensive chemotherapy and surgery. J Clin Oncol 19:2821-2828
7. Matthay KK, Villablanca JG, Seeger RC et al (1999) Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group. N Engl J Med 341:1165-1173
8. McGinn CJ, Kinsella TJ (1992) The experimental and clinical rationale for the use of S-phase-specific radiosensitizers to overcome tumor cell repopulation. Semin Oncol 19:21-28
9. Chen X, Shen B, Xia L et al (2002) Activation of nuclear factor kappa B in radioresistance of TP53-inactive human keratinocytes. Cancer Res 62:1213-1221
10. Li Z, Xia L, Lee LM et al (2001) Effector genes altered in MCF-7 human breast cancer cells after exposure to fractionated ionizing radiation. Radiat Res 155:543-553
11. Guo G, Yan-Sanders Y, Lyn-Cook BD et al (2003) Manganese superoxide dismutase-mediated gene expression in radiation-induced adaptive responses. Mol Cell Biol 23:2362-2378
12. Joki T, Carroll RS, Dunn IF et al (2001) Assessment of alterations in gene expression in recurrent malignant glioma after radiotherapy using complementary deoxyribonucleic acid microarrays. Neurosurgery 48:195-201
13. Lehnert S (2000) Prediction of tumor response to therapy: Molecular markers and the microenvironment. Apoptosis and chips: An overview of the proceedings. Radiat Res 154:121-124
14. Ishigami T, Uzawa K, Higo M et al (2007) Genes and molecular pathways related to radioresistance of oral squamous cell carcinoma cells. Int J Cancer 120:2262-2270
15. Fukuda K, Sakakura C, Miyagawa K et al (2004) Differential gene expression profiles of radioresistant oesophageal cancer cell lines established by continuous fractionated irradiation. Br J Cancer 91:1543-1550
16. Rosen EM, Fan S, Rockwell S, Goldberg ID (1999) The molecular and cellular basis of radiosensitivity: Implications for understanding how normal tissues and tumors respond to therapeutic radiation. Cancer Invest 17:56-72
17. Guo WF, Lin RX, Huang J et al (2005) Identification of differentially expressed genes contributing to radioresistance in lung cancer cells using microarray analysis. Radiat Res 164:27-35
18. Ogawa K, Utsunomiya T, Mimori K et al (2006) Differential gene expression profiles of radioresistant pancreatic cancer cell lines established by fractionated irradiation. Int J Oncol 28:705-713
19. Fornace AJ Jr, Amundson SA, Bittner M et al (1999) The complexity of radiation stress responses:aNalysis by informatics and functional genomics approaches. Gene Expr 7:387-400
20. Maity A, McKenna WG, Muschel RJ (1994) The molecular basis for cell cycle delays following ionizing radiation: A review. Radiother Oncol 31:1-13
21. Schmidt-Ullrich RK, Contessa JN, Dent P et al (1999) Molecular mechanisms of radiation-induced accelerated repopulation. Radiat Oncol Investig 7:321-330
22. Dewey WC, Ling CC, Meyn RE (1995) Radiation-induced apoptosis: Relevance to radiotherapy. Int J Radiat Oncol Biol Phys 33:781-796
23. Meyn RE, Stephens LC, Milas L (1996) Programmed cell death and radioresistance. Cancer Metastasis Rev 15:119-131
24. Sirzen F, Zhivotovsky B, Nilsson A et al (1998) Spontaneous and radiation-induced apoptosis in lung carcinoma cells with different intrinsic radiosensitivities. Anticancer Res 18:695-699
25. Wheeler JA, Stephens LC, Tornos C et al (1995) ASTRO Research Fellowship: Apoptosis as a predictor of tumor response to radiation in stage IB cervical carcinoma. Int J Radiat Oncol Biol Phys 32:1487-1493
26. Dubray B, Breton C, Delic J et al (1997) In vitro radiation-induced apoptosis and tumour response to radiotherapy: A prospective study in patients with non-Hodgkin lymphomas treated by low-dose irradiation. Int J Radiat Biol 72:759-760
27. Levine EL, Renehan A, Gossiel R et al (1995) Apoptosis, intrinsic radiosensitivity and prediction of radiotherapy response in cervical carcinoma. Radiother Oncol 37:1-9
28. Aravindan N, Natarajan M, Shaw AD (2006) Fenoldopam inhibits nuclear translocation of nuclear factor kappa B in a rat model of surgical ischemic acute renal failure. J Cardiothorac Vasc Anesth 20:179-186
29. Aravindan N, Cata JP, Dougherty PM, Shaw AD (2006): Effect of fenoldopam on ischemia/reperfusion-induced apoptosis. Ren Fail 28:337-344
30. Aravindan N, Cata JP, Hoffman L et al (2006) Effects of isoflurane, pentobarbital, and urethane on apoptosis and apoptotic signal transduction in rat kidney. Acta Anaesthesiol Scand 50:1229-1237
31. Tang Y, Lu A, Aronow BJ et al (2002) Genomic responses of the brain to ischemic stroke, intracerebral haemorrhage, kainate seizures, hypoglycemia, and hypoxia. Eur J Neurosci 15:1937-1952
32. Vidair CA, Chen CH, Ling CC, Dewey WC (1996) Apoptosis induced by X-irradiation of rec-myc cells is postmitotic and not predicted by the time after irradiation or behavior of sister cells. Cancer Res 56:4116-4118
33. Fanidi A, Harrington EA, Evan GI (1992) Cooperative interaction between c-myc and bcl-2 proto-oncogenes. Nature 359:554-556
34. Chen CH, Zhang J, Ling CC (1994) Transfected c-myc and c-Ha-ras modulate radiation-induced apoptosis in rat embryo cells. Radiat Res 139:307-315
35. Hallahan DE, Spriggs DR, Beckett MA et al (1989) Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation. Proc Natl Acad Sci USA 86:10104-10107
36. Van Antwerp DJ, Martin SJ, Kafri T et al (1996) Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science 274:787-789
37. Voboril R, Weberova-Voborilova J (2006) Constitutive NF-kappaB activity in colorectal cancer cells: Impact on radiation-induced NF-kappaB activity, radiosensitivity, and apoptosis. Neoplasma 53:518-523
38. Nam SY, Chung HY (2005): The suppression of radiation-induced NF-kappaB activity by dexamethasone correlates with increased cell death in vivo. Biochem Biophys Res Commun 336:603-608
39. Kim BY, Kim KA, Kwon O (2005) NF-kappaB inhibition radiosensitizes Ki-Ras-transformed cells to ionizing radiation. Carcinogenesis 26:1395-1403
40. Nakanishi C, Toi M (2005) Nuclear factor-kappa B inhibitors as sensitizers to anticancer drugs. Nat Rev Cancer 5:297-309
41. Ravi R, Bedi A (2004) NF-kappaB in cancer - a friend turned foe. Drug Resist Updat 7:53-67
42. Boothman DA, Majmudar G, Johnson T (1994) Immediate X-ray-inducible responses from mammalian cells. Radiat Res 138:S44-S46
43. Prasad AV, Mohan N, Chandrasekar B, Meltz ML (1994) Activation of nuclear factor kappa B in human lymphoblastoid cells by low-dose ionizing radiation. Radiat Res 138:367-372
44. Matsubara J, Turcanu V, Poindron P, Ina Y (2000): Immune effects of low-dose radiation: Short-term induction of thymocyte apoptosis and long-term augmentation of T-cell-dependent immune responses. Radiat Res 153:332-338
45. Skov KA (1994) Molecular, cellular, and genetic basis of radiosensitivity at low doses: A case of inducible repair? Radiat Res 138:S1-S4
46. Coleman MA, Yin E, Peterson LE et al (2005) Low-dose irradiation alters the transcript profiles of human lymphoblastoid cells including genes associated with cytogenetic radioadaptive response. Radiat Res 164:369-382
47. Koterov AN, Filippovich IV (2002) Radioadaptive response in vitro of unstimulated rat lymphocytes according to metallothionein test. Radiats Biol Radioecol 42:130-135
48. Lanza V, Pretazzoli V, Olivieri G et al (2005) Transcriptional response of human umbilical vein endothelial cells to low doses of ionizing radiation. J Radiat Res (Tokyo) 46:265-276
49. Hang H, Lieberman HB (2000) Physical interactions among human checkpoint control proteins HUS1p, RAD1p, and RAD9p, and implications for the regulation of cell cycle progression. Genomics 65:24-33
50. Eichholtz-Wirth H, Sagan D (2002) Altered signaling of TNFalpha-TNFR1 and SODD/BAG4 is responsible for radioresistance in human HT-R15 cells. Anticancer Res 22:235-240
51. Neta R, Oppenheim JJ, Schreiber RD et al (1991) Role of cytokines (interleukin 1, tumor necrosis factor, and transforming growth factor beta) in natural and lipopolysaccharide-enhanced radioresistance. J Exp Med 173:1177-1182
52. Sandur SK, Ichikawa H, Sethi G et al (2006) Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents. J Biol Chem 281:17023-17033
53. Yi MJ, Park SH, Cho HN et al (2002) Heat-shock protein 25 (Hspb1) regulates manganese superoxide dismutase through activation of Nfkb (NF-kappaB). Radiat Res 158:641-649
54. Skvara H, Thallinger C, Wacheck V et al (2005) Mcl-1 blocks radiation-induced apoptosis and inhibits clonogenic cell death. Anticancer Res 25:2697-2703
55. Chin C, Bae JH, Kim MJ et al (2005) Radiosensitization by targeting radioresistance-related genes with protein kinase A inhibitor in radioresistant cancer cells. Exp Mol Med 37:608-618
56. Nix P, Cawkwell L, Patmore H et al (2005) Bcl-2 expression predicts radiotherapy failure in laryngeal cancer. Br J Cancer 92:2185-2189
57. Reed JC (1996) Mechanisms of Bcl-2 family protein function and dysfunction in health and disease. Behring Inst Mitt 97:72-100
58. Schwartz JL, Jordan R, Slovic J et al (2007) Induction and loss of a TP53-dependent radioadaptive response in the human lymphoblastoid cell model TK6 and its abrogation by BCL2 over-expression. Int J Radiat Biol 83:153-159
59. Ferrer I (1999) Role of caspases in ionizing radiation-induced apoptosis in the developing cerebellum. J Neurobiol 41:549-558
60. Ramaswamy M, Efimova EV, Martinez O et al (2004) IG20 (MADD splice variant-5), a proapoptotic protein, interacts with DR4/DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC. Oncogene 23:6083-6094
61. Heminger K, Jain V, Kadakia M et al (2006) Altered gene expression induced by ionizing radiation and glycolytic inhibitor 2-deoxy-glucose in a human glioma cell line: Implications for radio sensitization. Cancer Biol Ther 5:815-823
62. Hildesheim J, Bulavin DV, Anver MR (2002) Gadd45a protects against UV irradiation-induced skin tumors, and promotes apoptosis and stress signaling via MAPK and p53. Cancer Res 62:7305-7315
63. Morgan MJ, Thorburn J, Thomas L et al (2001) An apoptosis signaling pathway induced by the death domain of FADD selectively kills normal but not cancerous prostate epithelial cells. Cell Death Differ 8:696-705
64. Chazal M, Marionnet C, Michel L et al (2002) P16(INK4A) is implicated in both the immediate and adaptative response of human keratinocytes to UVB irradiation. Oncogene 21:2652-2661
65. Kataoka T, Schroter M, Hahne M et al (1998) FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation. J Immunol 161:3936-3942
66. Chaudhry MA (2006) Radiation-induced gene expression profile of human cells deficient in 8-hydroxy-2′-deoxyguanine glycosylase. Int J Cancer 118:633-642
67. Padanilam BJ (2003) Cell death induced by acute renal injury: A perspective on the contributions of apoptosis and necrosis. Am J Physiol Renal Physiol 284:F608-F627