Nociceptin receptor impairs recognition memory via interaction with NMDA receptor-dependent mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in the hippocampus

Journal of Neuroscience

Volumn 28, Issue 9, 2008, Pages 2190-2198

  Goeldner, Celia ^a   Reiss, David ^a   Wichmann, Jürgen ^c   Meziane, Hamid ^b   Kieffer, Brigitte L ^a   Ouagazzal, Abdel Mouttalib ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b INSTITUT CLINIQUE DE LA SOURIS   (France)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

ERK; Hippocampus; Mice; NMDA receptor; NOP receptor; Opioid; Recognition memory

Indexed keywords

8 (2,3,3A,4,5,6 HEXAHYDRO 1H PHENALEN 1 YL) 1 PHENYL 1,3,8 TRIAZASPIRO[4.5]DECAN 4 ONE; ALPHA [AMINO(4 AMINOPHENYLTHIO)METHYLENE] 2 (TRIFLUOROMETHYL)PHENYLACETONITRILE; DIZOCILPINE; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NOCICEPTIN RECEPTOR; NOCICEPTIN RECEPTOR ANTAGONIST;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; HIPPOCAMPUS; LONG TERM MEMORY; MALE; MEMORY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECOGNITION; TASK PERFORMANCE;

ANIMALS; BEHAVIOR, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME ACTIVATION; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGENTS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HIPPOCAMPUS; MALE; MEMORY; MICE; MICE, INBRED C57BL; NEUROPSYCHOLOGICAL TESTS; OPIOID PEPTIDES; PATTERN RECOGNITION, VISUAL; RECEPTORS, N-METHYL-D-ASPARTATE; SIGNAL TRANSDUCTION;

EID: 39849098174     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3711-07.2008     Document Type: Article

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