Modeling resistance index of taxoids to MCF-7 cell lines using ANN together with electrotopological state descriptors

Acta Pharmacologica Sinica

Volumn 29, Issue 3, 2008, Pages 385-396

  Dong, Pei Pei ^a,b   Zhang, Yan Yan ^a,b   Ge, Guang Bo ^a,b   Ai, Chun Zhi ^a,b   Liu, Yong ^a   Yang, Ling ^a   Liu, Chang Xiao ^c  

^a DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH   (China)

Author keywords

Artificial neural network model; Electrotopological state indices; Multidrug resistance; Principle component analysis; Quantitative structure activity relationship; Resistance index; Taxoids

Indexed keywords

DOCETAXEL; PACLITAXEL; TAXOID;

ARTICLE; ARTIFICIAL NEURAL NETWORK; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRINCIPAL COMPONENT ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; VALIDATION STUDY;

EID: 39849087997     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2008.00746.x     Document Type: Article

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