Tight junction biogenesis during early development

Biochimica et Biophysica Acta - Biomembranes

Volumn 1778, Issue 3, 2008, Pages 717-728

  Eckert, Judith J ^a,b   Fleming, Tom P ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

Adherens junction; Blastocyst; Blastula; Cell polarity; Cell cell interactions; Compaction; Mouse embryo; Protein kinase C; Tight junction; Trophectoderm; Xenopus embryo

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); PROTEIN KINASE C;

AMPHIBIA; BIOGENESIS; BIOSYNTHESIS; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL ENERGY; CELL INTERACTION; CELL TRANSPORT; EMBRYO DEVELOPMENT; EPITHELIUM; HUMAN; MORPHOGENESIS; NONHUMAN; OOCYTE CLEAVAGE; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; TIGHT JUNCTION;

ANIMALS; BLASTOCYST; CELL ADHESION; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EMBRYONIC DEVELOPMENT; ENERGY METABOLISM; FEMALE; GAP JUNCTIONS; HUMANS; MICE; MODELS, BIOLOGICAL; MORPHOGENESIS; PREGNANCY; SIGNAL TRANSDUCTION; SODIUM-POTASSIUM-EXCHANGING ATPASE; TIGHT JUNCTIONS; XENOPUS;

AMPHIBIA; MAMMALIA;

EID: 39849084922     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2007.09.031     Document Type: Review

References (172)

1. 2+ signalling at fertilization in mammals. Semin. Cell Dev. Biol. 12 (2001) 37
2. Latham K.E., and Schultz R.M. Embryonic genome activation. Front Biosci. 6 (2001) D748-D759
3. Kidder G.M., and McLachlin J.R. Timing of transcription and protein synthesis underlying morphogenesis in preimplantation mouse embryos. Dev. Biol. 112 (1985) 265
4. Levy J.B., Johnson M.H., Goodall H., and Maro B. The timing of compaction: control of a major developmental transition in mouse early embryogenesis. J. Embryol. Exp. Morphol. 95 (1986) 213
5. Vestweber D., Gossler A., Boller K., and Kemler R. Expression and distribution of cell adhesion molecule uvomorulin in mouse preimplantation embryos. Dev. Biol. 124 (1987) 451
6. Hyenne V., Louvet-Vallee S., El-Amraoui A., Petit C., Maro B., and Simmler M.C. Vezatin, a protein associated to adherens junctions, is required for mouse blastocyst morphogenesis. Dev. Biol. 287 (2005) 180
7. Hyenne V., Souilhol C., Cohen-Tannoudji M., Cereghini S., Petit C., Langa F., Maro B., and Simmler M.C. Conditional knock-out reveals that zygotic vezatin-null mouse embryos die at implantation. Mech. Dev. 124 (2007) 449
8. Thomas F.C., Sheth B., Eckert J.J., Bazzoni G., Dejana E., and Fleming T.P. Contribution of JAM-1 to epithelial differentiation and tight-junction biogenesis in the mouse preimplantation embryo. J. Cell Sci. 117 (2004) 5599
9. Winkel G.K., Ferguson J.E., Takeichi M., and Nuccitelli R. Activation of protein kinase C triggers premature compaction in the four-cell stage mouse embryo. Dev. Biol. 138 (1990) 1
10. Ohsugi M., Ohsawa T., and Yamamura H. Involvement of protein kinase C in nuclear migration during compaction and the mechanism of the migration: analyses in two-cell mouse embryos. Dev. Biol. 156 (1993) 146
11. 2+/calmodulin-dependent enzyme. J. Exp. Zool. 274 (1996) 101
12. Pauken C.M., and Capco D.G. Regulation of cell adhesion during embryonic compaction of mammalian embryos: roles for PKC and β-catenin. Mol. Reprod. Dev. 54 (1999) 135
13. Goval J.J., and Alexandre H. Effect of genistein on the temporal coordination of cleavage and compaction in mouse preimplantation embryos. Eur. J. Morphol. 38 (2000) 88
14. Kawai Y., Yamaguchi T., Yoden T., Hanada M., and Miyake M. Effect of protein phosphatase inhibitors on the development of mouse embryos: protein phosphorylation is involved in the E-cadherin distribution in mouse two-cell embryos. Biol. Pharm. Bull. 25 (2002) 179
15. Fleming T.P., Wilkins A., Mears A., Miller D.J., Thomas F., Ghassemifar M.R., Fesenko I., Sheth B., Kwong W.Y., and Eckert J.J. Society for Reproductive Biology founders' lecture 2003. The making of an embryo: short-term goals and long-term implications. Reprod. Fertil. Dev. 16 (2004) 325
16. Khang I., Sonn S., Park J.H., Rhee K., Park D., and Kim K. Expression of epithin in mouse preimplantation development: its functional role in compaction. Dev. Biol. 281 (2005) 134
17. Ohsugi M., Butz S., and Kemler R. β-catenin is a major tyrosine-phosphorylated protein during mouse oocyte maturation and preimplantation development. Dev. Dyn. 216 (1999) 168
18. Handyside A.H. Distribution of antibody- and lectin-binding sites on dissociated blastomeres from mouse morulae: evidence for polarization at compaction. J. Embryol. Exp. Morphol. 60 (1980) 99
19. Dard N., Louvet S., Santa-Maria A., Aghion J., Martin M., Mangeat P., and Maro B. In vivo functional analysis of ezrin during mouse blastocyst formation. Dev. Biol. 233 (2001) 161
20. Dard N., Louvet-Vallee S., Santa-Maria A., and Maro B. Phosphorylation of ezrin on threonine T567 plays a crucial role during compaction in the mouse early embryo. Dev. Biol. 271 (2004) 87
21. Johnson M.H., and Maro B. The distribution of cytoplasmic actin in mouse 8-cell blastomeres. J. Embryol. Exp. Morphol. 82 (1984) 97
22. Fleming T.P., and Pickering S.J. Maturation and polarization of the endocytotic system in outside blastomeres during mouse preimplantation development. J. Embryol. Exp. Morphol. 89 (1985) 175
23. Houliston E., Pickering S.J., and Maro B. Redistribution of microtubules and pericentriolar material during the development of polarity in mouse blastomeres. J. Cell Biol. 104 (1987) 1299
24. Clayton L., Hall A., and Johnson M.H. A role for Rho-like GTPases in the polarisation of mouse eight-cell blastomeres. Dev. Biol. 205 (1999) 322
25. Ahringer J. Control of cell polarity and mitotic spindle positioning in animal cells. Curr. Opin. Cell Biol. 15 (2003) 73
26. Macara I.G. Par proteins: partners in polarization. Curr. Biol. 14 (2004) R160-R162
27. Ebnet K., Suzuki A., Horikoshi Y., Hirose T., Meyer zu Brickwedde M.K., Ohno S., and Vestweber D. The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM). EMBO J. 20 (2001) 3738
28. Betschinger J., Mechtler K., and Knoblich J.A. The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. Nature 422 (2003) 326
29. Plusa B., Frankenberg S., Chalmers A., Hadjantonakis A.K., Moore C.A., Papalopulu N., Papaioannou V.E., Glover D.M., and Zernicka-Goetz M. Downregulation of Par3 and aPKC function directs cells towards the ICM in the preimplantation mouse embryo. J. Cell Sci. 118 (2005) 505
30. Vinot S., Le T., Ohno S., Pawson T., Maro B., and Louvet-Vallee S. Asymmetric distribution of PAR proteins in the mouse embryo begins at the 8-cell stage during compaction. Dev. Biol. 282 (2005) 307
31. Hirose T., Karasawa M., Sugitani Y., Fujisawa M., Akimoto K., Ohno S., and Noda T. PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains. Development 133 (2006) 1389
32. Larue L., Ohsugi M., Hirchenhain J., and Kemler R. E-cadherin null mutant embryos fail to form a trophectoderm epithelium. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 8263
33. Riethmacher D., Brinkmann V., and Birchmeier C. A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 855
34. Torres M., Stoykova A., Huber O., Chowdhury K., Bonaldo P., Mansouri A., Butz S., Kemler R., and Gruss P. An α-E-catenin gene trap mutation defines its function in preimplantation development. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 901
35. de Vries W.N., Evsikov A.V., Haac B.E., Fancher K.S., Holbrook A.E., Kemler R., Solter D., and Knowles B.B. Maternal β-catenin and E-cadherin in mouse development. Development 131 (2004) 4435
36. Wianny F., and Zernicka-Goetz M. Specific interference with gene function by double-stranded RNA in early mouse development. Nat. Cell Biol. 2 (2000) 70
37. Kan N.G., Stemmler M.P., Junghans D., Kanzler B., de Vries W.N., Dominis M., and Kemler R. Gene replacement reveals a specific role for E-cadherin in the formation of a functional trophectoderm. Development 134 (2007) 31
38. Fleming T.P., Sheth B., and Fesenko I. Cell adhesion in the preimplantation mammalian embryo and its role in trophectoderm differentiation and blastocyst morphogenesis. Front Biosci. 6 (2001) D1000-D1007
39. Gonzalez-Mariscal L., Betanzos A., Nava P., and Jaramillo B.E. Tight junction proteins. Prog. Biophys. Molec. Biol. 81 (2003) 1
40. Fleming T.P., McConnell J., Johnson M.H., and Stevenson B.R. Development of tight junctions de novo in the mouse early embryo: control of assembly of the tight junction-specific protein, ZO-1. J. Cell Biol. 108 (1989) 1407
41. + isoform. Development 124 (1997) 2027
42. Sheth B., Fontaine J.J., Ponza E., McCallum A., Page A., Citi S., Louvard D., Zahraoui A., and Fleming T.P. Differentiation of the epithelial apical junctional complex during mouse preimplantation development: a role for rab13 in the early maturation of the tight junction. Mech. Dev. 97 (2000) 93
43. Balda M.S., and Anderson J.M. Two classes of tight junctions are revealed by ZO-1 isoforms. Am. J. Physiol 264 (1993) C918-C924
44. Javed Q., Fleming T.P., Hay M., and Citi S. Tight junction protein cingulin is expressed by maternal and embryonic genomes during early mouse development. Development 117 (1993) 1145
45. Sheth B., Moran B., Anderson J.M., and Fleming T.P. Post-translational control of occludin membrane assembly in mouse trophectoderm: a mechanism to regulate timing of tight junction biogenesis and blastocyst formation. Development 127 (2000) 831
46. Hamatani T., Carter M.G., Sharov A.A., and Ko M.S. Dynamics of global gene expression changes during mouse preimplantation development. Dev. Cell 6 (2004) 117
47. Cui X.S., Li X.Y., Shen X.H., Bae Y.J., Kang J.J., and Kim N.H. Transcription profile in mouse four-cell, morula, and blastocyst: genes implicated in compaction and blastocoel formation. Mol. Reprod. Dev. 74 (2007) 133
48. Kim J., Gye M.C., and Kim M.K. Role of occludin, a tight junction protein, in blastocoel formation, and in the paracellular permeability and differentiation of trophectoderm in preimplantation mouse embryos. Mol Cells 17 (2004) 248
49. Hopfer U., Jacobberger J.W., Gruenert D.C., Eckert R.L., Jat P.S., and Whitsett J.A. Immortalization of epithelial cells. Am. J. Physiol 270 (1996) C1
50. Aijaz S., Balda M.S., and Matter K. Tight junctions: molecular architecture and function. Int. Rev. Cytol. 248 (2006) 261
51. Sabath E., and Denker B.M. Cell-cell interactions in the kidney: inducible expression of mutant G protein α-subunits in Madin-Darby canine kidney cells for studies of epithelial cell junction structure and function. Methods Mol. Biol. 341 (2006) 61
52. Johnson M.H. Molecular differentiation of inside cells and inner cell masses isolated from the preimplantation mouse embryo. J. Embryol. Exp. Morphol. 53 (1979) 335
53. Kimber S.J., Surani M.A., and Barton S.C. Interactions of blastomeres suggest changes in cell surface adhesiveness during the formation of inner cell mass and trophectoderm in the preimplantation mouse embryo. J. Embryol. Exp. Morphol. 70 (1982) 133
54. Schock F., and Perrimon N. Molecular mechanisms of epithelial morphogenesis. Annu. Rev. Cell Dev. Biol. 18 (2002) 463
55. Fleming T.P., Warren P.D., Chisholm J.C., and Johnson M.H. Trophectodermal processes regulate the expression of totipotency within the inner cell mass of the mouse expanding blastocyst. J. Embryol. Exp. Morphol. 84 (1984) 63
56. Eckert J.J., McCallum A., Mears A., Rumsby M.G., Cameron I.T., and Fleming T.P. PKC signalling regulates tight junction membrane assembly in the pre-implantation mouse embryo. Reproduction. 127 (2004) 653
57. Fagotto F., and Gumbiner B.M. Cell contact-dependent signaling. Dev. Biol. 180 (1996) 445
58. Boudreau N.J., and Jones P.L. Extracellular matrix and integrin signalling: the shape of things to come. Biochem. J. 339 Pt 3 (1999) 481
59. Boudreau N.J. Organized living: from cell surfaces to basement membranes. Sci. STKE. 2003 (2003) e34
60. Sueoka K., Shiokawa S., Miyazaki T., Kuji N., Tanaka M., and Yoshimura Y. Integrins and reproductive physiology: expression and modulation in fertilization, embryogenesis, and implantation. Fertil. Steril. 67 (1997) 799
61. Bowen J.A., and Hunt J.S. The role of integrins in reproduction. Proc. Soc. Exp. Biol. Med. 223 (2000) 331
62. Fleming T.P., and Hay M.J. Tissue-specific control of expression of the tight junction polypeptide ZO-1 in the mouse early embryo. Development 113 (1991) 295
63. Eckert J.J., McCallum A., Mears A., Rumsby M.G., Cameron I.T., and Fleming T.P. Specific PKC isoforms regulate blastocoel formation during mouse preimplantation development. Dev. Biol. 274 (2004) 384
64. Kelly S.J., Mulnard J.G., and Graham C.F. Cell division and cell allocation in early mouse development. J. Embryol. Exp. Morphol. 48 (1978) 37
65. Johnson M.H., and McConnell J.M. Lineage allocation and cell polarity during mouse embryogenesis. Semin. Cell Dev. Biol. 15 (2004) 583
66. Hiiragi T., Alarcon V.B., Fujimori T., Louvet-Vallee S., Maleszewski M., Marikawa Y., Maro B., and Solter D. Where do we stand now? Mouse early embryo patterning meeting in Freiburg, Germany (2005). Int. J. Dev. Biol. 50 (2006) 581
67. Zernicka-Goetz M. The first cell-fate decisions in the mouse embryo: destiny is a matter of both chance and choice. Curr. Opin. Genet. Dev. 16 (2006) 406
68. Spindle A.I. Trophoblast regeneration by inner cell masses isolated from cultured mouse embryos. J. Exp. Zool. 203 (1978) 483
69. Handyside A.H. Time of commitment of inside cells isolated from preimplantation mouse embryos. J. Embryol. Exp. Morphol. 45 (1978) 37
70. Rossant J., and Lis W.T. Potential of isolated mouse inner cell masses to form trophectoderm derivatives in vivo. Dev. Biol. 70 (1979) 255
71. Chisholm J.C., Johnson M.H., Warren P.D., Fleming T.P., and Pickering S.J. Developmental variability within and between mouse expanding blastocysts and their ICMs. J. Embryol. Exp. Morphol. 86 (1985) 311
72. Louvet-Vallee S., Dard N., Santa-Maria A., Aghion J., and Maro B. A major posttranslational modification of ezrin takes place during epithelial differentiation in the early mouse embryo. Dev. Biol. 231 (2001) 190
73. Eckert J.J., McCallum A., Mears A., Rumsby M.G., Cameron I.T., and Fleming T.P. Relative contribution of cell contact pattern, specific PKC isoforms and gap junctional communication in tight junction assembly in the mouse early embryo. Dev. Biol. 288 (2005) 234
74. Azim M., Surani H., Torchiana D., and Barton S.C. Isolation and development of the inner cell mass after exposure of mouse embryos to calcium ionophore A23187. J. Embryol. Exp. Morphol. 45 (1978) 237
75. Gueth-Hallonet C., Santa-Maria A., Verroust P., and Maro B. Gp330 is specifically expressed in outer cells during epithelial differentiation in the preimplantation mouse embryo. Development 120 (1994) 3289
76. Denker B.M., and Nigam S.K. Molecular structure and assembly of the tight junction. Am. J. Physiol 274 (1998) F1-F9
77. Braga V.M. Cell-cell adhesion and signalling. Curr. Opin. Cell Biol. 14 (2002) 546
78. Hurd T.W., Gao L., Roh M.H., Macara I.G., and Margolis B. Direct interaction of two polarity complexes implicated in epithelial tight junction assembly. Nat. Cell Biol. 5 (2003) 137
79. Allworth A.E., Hildebrandt J.D., and Ziomek C.A. Differential regulation of G protein subunit expression in mouse oocytes, eggs, and early embryos. Dev. Biol. 142 (1990) 129
80. Rambhatla L., Patel B., Dhanasekaran N., and Latham K.E. Analysis of G protein α subunit mRNA abundance in preimplantation mouse embryos using a rapid, quantitative RT-PCR approach. Mol Reprod. Dev. 41 (1995) 314
81. Williams C.J., Schultz R.M., and Kopf G.S. G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development. Mol Reprod. Dev. 44 (1996) 315
82. Natale D.R., and Watson A.J. Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development. Gene Expr. Patterns. 2 (2002) 17
83. Benais-Pont G., Punn A., Flores-Maldonado C., Eckert J., Raposo G., Fleming T.P., Cereijido M., Balda M.S., and Matter K. Identification of a tight junction-associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability. J. Cell Biol. 160 (2003) 729
84. Pauken C.M., and Capco D.G. The expression and stage-specific localization of protein kinase C isotypes during mouse preimplantation development. Dev. Biol. 223 (2000) 411
85. Dehghani H., and Hahnel A.C. Expression profile of protein kinase C isozymes in preimplantation mouse development. Reproduction 130 (2005) 441
86. Mellor H., and Parker P.J. The extended protein kinase C superfamily. Biochem. J. 332 (1998) 281 (Pt 2)
87. Dempsey E.C., Newton A.C., Mochly-Rosen D., Fields A.P., Reyland M.E., Insel P.A., and Messing R.O. Protein kinase C isozymes and the regulation of diverse cell responses. Am. J. Physiol., Lung Cell. Mol. Physiol. 279 (2000) L429-L438
88. Jaken S., and Parker P.J. Protein kinase C binding partners. Bioessays 22 (2000) 245
89. Mochly-Rosen D., and Gordon A.S. Anchoring proteins for protein kinase C: a means for isozyme selectivity. FASEB J. 12 (1998) 35
90. Schechtman D., and Mochly-Rosen D. Adaptor proteins in protein kinase C-mediated signal transduction. Oncogene 20 (2001) 6339
91. Andreeva A.Y., Krause E., Muller E.C., Blasig I.E., and Utepbergenov D.I. Protein kinase C regulates the phosphorylation and cellular localization of occludin. J. Biol. Chem. 276 (2001) 38480
92. Avila-Flores A., Rendon-Huerta E., Moreno J., Islas S., Betanzos A., Robles-Flores M., and Gonzalez-Mariscal L. Tight-junction protein zonula occludens 2 is a target of phosphorylation by protein kinase C. Biochem. J. 360 (2001) 295
93. Weiler F., Marbe T., Scheppach W., and Schauber J. Influence of protein kinase C on transcription of the tight junction elements ZO-1 and occludin. J. Cell Physiol 204 (2005) 83
94. Leotlela P.D., Wade M.S., Duray P.H., Rhode M.J., Brown H.F., Rosenthal D.T., Dissanayake S.K., Earley R., Indig F.E., Nickoloff B.J., Taub D.D., Kallioniemi O.P., Meltzer P., Morin P.J., and Weeraratna A.T. Claudin-1 overexpression in melanoma is regulated by PKC and contributes to melanoma cell motility. Oncogene (2006)
95. Souroujon M.C., and Mochly-Rosen D. Peptide modulators of protein-protein interactions in intracellular signaling. Nat. Biotechnol. 16 (1998) 919
96. D'Atri F., and Citi S. Molecular complexity of vertebrate tight junctions (review). Mol Membr. Biol. 19 (2002) 103
97. Chen M.L., Pothoulakis C., and LaMont J.T. Protein kinase C signaling regulates ZO-1 translocation and increased paracellular flux of T84 colonocytes exposed to Clostridium difficile toxin A. J. Biol. Chem. 277 (2002) 4247
98. Stuart R.O., and Nigam S.K. Regulated assembly of tight junctions by protein kinase C. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 6072
99. Suzuki A., Yamanaka T., Hirose T., Manabe N., Mizuno K., Shimizu M., Akimoto K., Izumi Y., Ohnishi T., and Ohno S. Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures. J. Cell Biol. 152 (2001) 1183
100. Parkinson S.J., Le Good J.A., Whelan R.D., Whitehead P., and Parker P.J. Identification of PKCζII: an endogenous inhibitor of cell polarity. EMBO J. 23 (2004) 77
101. Watson A.J., and Barcroft L.C. Regulation of blastocyst formation. Front Biosci. 6 (2001) D708-D730
102. Rajasekaran S.A., Palmer L.G., Moon S.Y., Peralta S.A., Apodaca G.L., Harper J.F., Zheng Y., and Rajasekaran A.K. Na,K-ATPase activity is required for formation of tight junctions, desmosomes, and induction of polarity in epithelial cells. Mol Biol. Cell 12 (2001) 3717
103. +-ATPase regulates tight junction formation and function during mouse preimplantation development. Dev. Biol. 289 (2006) 406
104. Madan P., Rose K., and Watson A.J. Na/K-ATPase β1 subunit expression is required for blastocyst formation and normal assembly of trophectoderm tight junction-associated proteins. J. Biol. Chem. 282 (2007) 12127
105. Therien A.G., and Blostein R. Mechanisms of sodium pump regulation. Am. J. Physiol., Cell Physiol. 279 (2000) C541-C566
106. Vance M.M., and Wiley L.M. Gap junction intercellular communication mediates the competitive cell proliferation disadvantage of irradiated mouse preimplantation embryos in aggregation chimeras. Radiat. Res. 152 (1999) 544
107. Kidder G.M., and Winterhager E. Intercellular communication in preimplantation development: the role of gap junctions. Front Biosci. 6 (2001) D731-D736
108. White T.W., and Paul D.L. Genetic diseases and gene knockouts reveal diverse connexin functions. Annu. Rev. Physiol. 61 (1999) 283
109. Houghton F.D. Role of gap junctions during early embryo development. Reproduction 129 (2005) 129
110. Toyofuku T., Yabuki M., Otsu K., Kuzuya T., Hori M., and Tada M. Direct association of the gap junction protein connexin-43 with ZO-1 in cardiac myocytes. J. Biol. Chem. 273 (1998) 12725
111. Kausalya P.J., Reichert M., and Hunziker W. Connexin45 directly binds to ZO-1 and localizes to the tight junction region in epithelial MDCK cells. FEBS Lett. 505 (2001) 92
112. Giepmans B.N. Gap junctions and connexin-interacting proteins. Cardiovasc. Res. 62 (2004) 233
113. Kojima T., Spray D.C., Kokai Y., Chiba H., Mochizuki Y., and Sawada N. Cx32 formation and/or Cx32-mediated intercellular communication induces expression and function of tight junctions in hepatocytic cell line. Exp. Cell Res. 276 (2002) 40
114. Ogawa H., Oyamada M., Mori T., Mori M., and Shimizu H. Relationship of gap junction formation to phosphorylation of connexin43 in mouse preimplantation embryos. Mol Reprod. Dev. 55 (2000) 393
115. Wagner L.M., Saleh S.M., Boyle D.J., and Takemoto D.J. Effect of protein kinase Cγ on gap junction disassembly in lens epithelial cells and retinal cells in culture. Mol. Vis. 8 (2002) 59
116. Lampe P.D., and Lau A.F. The effects of connexin phosphorylation on gap junctional communication. Int. J. Biochem. Cell Biol. 36 (2004) 1171
117. Akoyev V., and Takemoto D.J. ZO-1 is required for protein kinase C γ-driven disassembly of connexin 43. Cell Signal 19 (2007) 958
118. Ren P., Mehta P.P., and Ruch R.J. Inhibition of gap junctional intercellular communication by tumor promoters in connexin43 and connexin32-expressing liver cells: cell specificity and role of protein kinase C. Carcinogenesis 19 (1998) 169
119. Lampe P.D., TenBroek E.M., Burt J.M., Kurata W.E., Johnson R.G., and Lau A.F. Phosphorylation of connexin43 on serine368 by protein kinase C regulates gap junctional communication. J. Cell Biol. 149 (2000) 1503
120. Kimball S.R. Interaction between the AMP-activated protein kinase and mTOR signaling pathways. Med. Sci. Sports Exerc. 38 (2006) 1958
121. Zhang L., Li J., Young L.H., and Caplan M.J. AMP-activated protein kinase regulates the assembly of epithelial tight junctions. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 17272
122. Zheng B., and Cantley L.C. Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 819
123. Massey-Harroche D., Delgrossi M.H., Lane-Guermonprez L., Arsanto J.P., Borg J.P., Billaud M., and Le B.A. Evidence for a molecular link between the tuberous sclerosis complex and the Crumbs complex. Hum. Mol Genet. 16 (2007) 529
124. Gopalakrishnan S., Hallett M.A., Atkinson S.J., and Marrs J.A. aPKC-PAR complex dysfunction and tight junction disassembly in renal epithelial cells during ATP depletion. Am. J. Physiol., Cell Physiol. 292 (2007) C1094-C1102
125. Pesce M., and Scholer H.R. Oct-4: gatekeeper in the beginnings of mammalian development. Stem Cells 19 (2001) 271
126. Nichols J., Zevnik B., Anastassiadis K., Niwa H., Klewe-Nebenius D., Chambers I., Scholer H., and Smith A. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95 (1998) 379
127. Niwa H., Miyazaki J., and Smith A.G. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat. Genet. 24 (2000) 372
128. Barcroft L.C., Hay-Schmidt A., Caveney A., Gilfoyle E., Overstrom E.W., Hyttel P., and Watson A.J. Trophectoderm differentiation in the bovine embryo: characterization of a polarized epithelium. J. Reprod. Fertil. 114 (1998) 327
129. Talbot N.C., and Garrett W.M. Ultrastructure of the embryonic stem cells of the 8-day pig blastocyst before and after in vitro manipulation: development of junctional apparatus and the lethal effects of PBS mediated cell-cell dissociation. Anat. Rec. 264 (2001) 101
130. Miller D.J., Eckert J.J., Lazzari G., Duranthon-Richoux V., Sreenan J., Morris D., Galli C., Renard J.P., and Fleming T.P. Tight junction messenger RNA expression levels in bovine embryos are dependent upon the ability to compact and in vitro culture methods. Biol. Reprod. 68 (2003) 1394
131. Wrenzycki C., Herrmann D., Carnwath J.W., and Niemann H. Expression of RNA from developmentally important genes in preimplantation bovine embryos produced in TCM supplemented with BSA. J. Reprod. Fertil. 112 (1998) 387
132. Wrenzycki C., Herrmann D., Carnwath J.W., and Niemann H. Alterations in the relative abundance of gene transcripts in preimplantation bovine embryos cultured in medium supplemented with either serum or PVA. Mol Reprod. Dev. 53 (1999) 8
133. Wrenzycki C., Herrmann D., and Niemann H. Timing of blastocyst expansion affects spatial messenger RNA expression patterns of genes in bovine blastocysts produced in vitro. Biol. Reprod. 68 (2003) 2073
134. Nikas G., Ao A., Winston R.M., and Handyside A.H. Compaction and surface polarity in the human embryo in vitro. Biol. Reprod. 55 32 (1996)
135. Bloor D.J., Metcalfe A.D., Rutherford A., Brison D.R., and Kimber S.J. Expression of cell adhesion molecules during human preimplantation embryo development. Mol. Hum. Reprod. 8 (2002) 237
136. Ghassemifar M.R., Eckert J.J., Houghton F.D., Picton H.M., Leese H.J., and Fleming T.P. Gene expression regulating epithelial intercellular junction biogenesis during human blastocyst development in vitro. Mol. Hum. Reprod. 9 (2003) 245
137. Eckert J.J., Houghton F.D., Hawkhead J.A., Balen A.H., Leese H.J., Picton H.M., Cameron I.T., and Fleming T.P. Human Embryos Developing in Vitro are Susceptible to Impaired Epithelial Junction Biogenesis Correlating with Abnormal Metabolic Activity (2007)
138. Hardy K., Warner A., Winston R.M., and Becker D.L. Expression of intercellular junctions during preimplantation development of the human embryo. Mol. Hum. Reprod. 2 (1996) 621
139. Alikani M. Epithelial cadherin distribution in abnormal human pre-implantation embryos. Hum. Reprod. 20 (2005) 3369
140. Wrenzycki C., Herrmann D., Carnwath J.W., and Niemann H. Expression of the gap junction gene connexin43 (Cx43) in preimplantation bovine embryos derived in vitro or in vivo. J. Reprod. Fertil. 108 (1996) 17
141. Rizos D., Gutierrez-Adan A., Moreira P., O'Meara C., Fair T., Evans A.C., Boland M.P., and Lonergan P. Species-related differences in blastocyst quality are associated with differences in relative mRNA transcription. Mol Reprod. Dev. 69 (2004) 381
142. Xu J.S., Lee Y.L., Lee K.F., Kwok K.L., Lee W.M., Luk J.M., and Yeung W.S. Embryotrophic factor-3 from human oviductal cells enhances proliferation, suppresses apoptosis and stimulates the expression of the β1 subunit of sodium-potassium ATPase in mouse embryos. Hum. Reprod. 19 (2004) 2919
143. Ohtake K., Maeno T., Ueda H., Ogihara M., Natsume H., and Morimoto Y. Poly-l-arginine enhances paracellular permeability via serine/threonine phosphorylation of ZO-1 and tyrosine dephosphorylation of occludin in rabbit nasal epithelium. Pharm. Res. 20 (2003) 1838
144. +, ATPase activity in the human and bovine preimplantation embryo. Dev. Biol. 263 (2003) 360
145. Cariappa R., Heath-Monnig E., and Smith C.H. Isoforms of amino acid transporters in placental syncytiotrophoblast: plasma membrane localization and potential role in maternal/fetal transport. Placenta 24 (2003) 713
146. Kohler K., and Zahraoui A. Tight junction: a co-ordinator of cell signalling and membrane trafficking. Biol. Cell 97 (2005) 659
147. Matter K., Aijaz S., Tsapara A., and Balda M.S. Mammalian tight junctions in the regulation of epithelial differentiation and proliferation. Curr. Opin. Cell Biol. 17 (2005) 453
148. Sourisseau T., Georgiadis A., Tsapara A., Ali R.R., Pestell R., Matter K., and Balda M.S. Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA. Mol. Cell. Biol. 26 (2006) 2387
149. Kavanagh E., Buchert M., Tsapara A., Choquet A., Balda M.S., Hollande F., and Matter K. Functional interaction between the ZO-1-interacting transcription factor ZONAB/DbpA and the RNA processing factor symplekin. J. Cell Sci. 119 (2006) 5098
150. Muller H.A., and Hausen P. Epithelial cell polarity in early Xenopus development. Dev. Dyn. 202 (1995) 405
151. Fleming T.P., Papenbrock T., Fesenko I., Hausen P., and Sheth B. Assembly of tight junctions during early vertebrate development. Semin. Cell Dev. Biol. 11 (2000) 291
152. Roberts S.J., Leaf D.S., Moore H.P., and Gerhart J.C. The establishment of polarized membrane traffic in Xenopus laevis embryos. J. Cell Biol. 118 (1992) 1359
153. Angres B., Muller A.H., Kellermann J., and Hausen P. Differential expression of two cadherins in Xenopus laevis. Development 111 (1991) 829
154. Ginsberg D., DeSimone D., and Geiger B. Expression of a novel cadherin (EP-cadherin) in unfertilized eggs and early Xenopus embryos. Development 111 (1991) 315
155. Muller H.A., Kuhl M., Finnemann S., Schneider S., van der Poel S.Z., Hausen P., and Wedlich D. Xenopus cadherins: the maternal pool comprises distinguishable members of the family. Mech. Dev. 47 (1994) 213
156. Munchberg F.E., Spieker T.P., Joos T.O., and Hausen P. A paired oocyte adhesion assay reveals the homophilic binding properties of the Xenopus maternal cadherins, XB/U- and EP-cadherin. Mech. Dev. 64 (1997) 87
157. Kurth T., Fesenko I.V., Schneider S., Munchberg F.E., Joos T.O., Spieker T.P., and Hausen P. Immunocytochemical studies of the interactions of cadherins and catenins in the early Xenopus embryo. Dev. Dyn. 215 (1999) 155
158. Kalt M.R. The relationship between cleavage and blastocoel formation in Xenopus laevis. I. Light microscopic observations. J. Embryol. Exp. Morphol. 26 (1971) 37
159. Nakaya M., Fukui A., Izumi Y., Akimoto K., Asashima M., and Ohno S. Meiotic maturation induces animal-vegetal asymmetric distribution of aPKC and ASIP/PAR-3 in Xenopus oocytes. Development 127 (2000) 5021
160. Chalmers A.D., Pambos M., Mason J., Lang S., Wylie C., and Papalopulu N. aPKC, Crumbs3 and Lgl2 control apicobasal polarity in early vertebrate development. Development 132 (2005) 977
161. Chalmers A.D., Strauss B., and Papalopulu N. Oriented cell divisions asymmetrically segregate aPKC and generate cell fate diversity in the early Xenopus embryo. Development 130 (2003) 2657
162. Strauss B., Adams R.J., and Papalopulu N. A default mechanism of spindle orientation based on cell shape is sufficient to generate cell fate diversity in polarised Xenopus blastomeres. Development 133 (2006) 3883
163. Slack C., and Warner A.E. Intracellular and intercellular potentials in the early amphibian embryo. J. Physiol. 232 (1973) 313
164. Merzdorf C.S., Chen Y.H., and Goodenough D.A. Formation of functional tight junctions in Xenopus embryos. Dev. Biol. 195 (1998) 187
165. Cardellini P., Davanzo G., and Citi S. Tight junctions in early amphibian development: detection of junctional cingulin from the 2-cell stage and its localization at the boundary of distinct membrane domains in dividing blastomeres in low calcium. Dev. Dyn. 207 (1996) 104
166. Chen Y., Merzdorf C., Paul D.L., and Goodenough D.A. COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos. J. Cell Biol. 138 (1997) 891
167. Fesenko I., Kurth T., Sheth B., Fleming T.P., Citi S., and Hausen P. Tight junction biogenesis in the early Xenopus embryo. Mech. Dev. 96 (2000) 51
168. Brizuela B.J., Wessely O., and De Robertis E.M. Overexpression of the Xenopus tight-junction protein claudin causes randomization of the left-right body axis. Dev. Biol. 230 (2001) 217
169. Cordenonsi M., Mazzon E., De R.L., Baraldo S., Meggio F., and Citi S. Occludin dephosphorylation in early development of Xenopus laevis. J. Cell Sci. 110 Pt 24 (1997) 3131
170. Umeda K., Ikenouchi J., Katahira-Tayama S., Furuse K., Sasaki H., Nakayama M., Matsui T., Tsukita S., Furuse M., and Tsukita S. ZO- and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation. Cell 126 (2006) 741
171. Yamanaka Y., Ralston A., Stephenson R.O., and Rossant J. Cell and molecular regulation of the mouse blastocyst. Dev. Dyn. 235 (2006) 2301
172. Handyside A.H., and Hunter S. A rapid procedure for visualising the inner cell mass and trophectoderm nuclei of mouse blastocysts in situ using polynucleotide-specific fluorochromes. J. Exp. Zool. 231 (1984) 429