Proton transfer in carbonic anhydrase is controlled by electrostatics rather than the orientation of the acceptor

Biochemistry

Volumn 47, Issue 8, 2008, Pages 2369-2378

  Riccardi, Demian ^a   König, Peter ^a   Guo, Hua ^b   Cui, Qiang ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; ELECTROSTATICS; PROTON TRANSFER;

CARBONIC ANHYDRASE; POTENTIALS OF MEAN FORCE (PMF);

ENZYME ACTIVITY;

CARBONATE DEHYDRATASE I;

ANALYTIC METHOD; ARTICLE; CONFORMATION; ELECTRICITY; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTON TRANSPORT; QUANTUM MECHANICS;

AMINO ACID MOTIFS; BINDING SITES; CARBONIC ANHYDRASE II; COMPUTER SIMULATION; ELECTROSTATICS; HISTIDINE; ION EXCHANGE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; PROTEIN BINDING; PROTEIN FOLDING; PROTONS;

EID: 39749169756     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi701950j     Document Type: Article

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