-
1
-
-
0027109075
-
Cancer. p53, guardian of the genome
-
Lane D.P. Cancer. p53, guardian of the genome. Nature 358 (1992) 15-16
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
2
-
-
1542319132
-
Turning the key on p53
-
Lane D.P., and Fischer P.M. Turning the key on p53. Nature 427 (2004) 789-790
-
(2004)
Nature
, vol.427
, pp. 789-790
-
-
Lane, D.P.1
Fischer, P.M.2
-
3
-
-
24944495794
-
p53: link to the past, bridge to the future
-
Mills A.A. p53: link to the past, bridge to the future. Genes Dev 19 (2005) 2091-2099
-
(2005)
Genes Dev
, vol.19
, pp. 2091-2099
-
-
Mills, A.A.1
-
4
-
-
0031583962
-
Oncoprotein MDM-2 is an ubiquitin ligase E3 for tumor suppressor p53
-
Honda R., Tanaka H., and Yasuda H. Oncoprotein MDM-2 is an ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett 420 (1997) 25-27
-
(1997)
FEBS Lett
, vol.420
, pp. 25-27
-
-
Honda, R.1
Tanaka, H.2
Yasuda, H.3
-
5
-
-
0842332406
-
Dynamics of the p53-MDM-2 feedback loop in individual cells
-
Lahav G., Rosenfeld N., Sigal A., Geva-Zatorsky N., Levine A.J., Elowitz M.B., et al. Dynamics of the p53-MDM-2 feedback loop in individual cells. Nat Genet 36 (2004) 147-150
-
(2004)
Nat Genet
, vol.36
, pp. 147-150
-
-
Lahav, G.1
Rosenfeld, N.2
Sigal, A.3
Geva-Zatorsky, N.4
Levine, A.J.5
Elowitz, M.B.6
-
6
-
-
0026649648
-
The MDM-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
-
Momand J., Zambetti G.P., Olson D.C., George D., and Levine A.J. The MDM-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69 (1992) 1237-1245
-
(1992)
Cell
, vol.69
, pp. 1237-1245
-
-
Momand, J.1
Zambetti, G.P.2
Olson, D.C.3
George, D.4
Levine, A.J.5
-
7
-
-
0034383398
-
p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation
-
Takekawa M., Adachi M., Nakahata A., Nakayama I., Itoh F., Tsukuda H., et al. p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation. Embo J 19 (2000) 6517-6526
-
(2000)
Embo J
, vol.19
, pp. 6517-6526
-
-
Takekawa, M.1
Adachi, M.2
Nakahata, A.3
Nakayama, I.4
Itoh, F.5
Tsukuda, H.6
-
8
-
-
0030925222
-
Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner
-
Fiscella M., Zhang H., Fan S., Sakaguchi K., Shen S., Mercer W.E., et al. Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner. Proc Natl Acad Sci USA 94 (1997) 6048-6053
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6048-6053
-
-
Fiscella, M.1
Zhang, H.2
Fan, S.3
Sakaguchi, K.4
Shen, S.5
Mercer, W.E.6
-
9
-
-
0036235121
-
Cyclin G recruits PP2A to dephosphorylate MDM-2
-
Okamoto K., Li H., Jensen M.R., Zhang T., Taya Y., Thorgeirsson S.S., et al. Cyclin G recruits PP2A to dephosphorylate MDM-2. Mol Cell 9 (2002) 761-771
-
(2002)
Mol Cell
, vol.9
, pp. 761-771
-
-
Okamoto, K.1
Li, H.2
Jensen, M.R.3
Zhang, T.4
Taya, Y.5
Thorgeirsson, S.S.6
-
10
-
-
33747819484
-
Divorcing ARF and p53: an unsettled case
-
Sherr C.J. Divorcing ARF and p53: an unsettled case. Nat Rev Cancer 6 (2006) 663-673
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 663-673
-
-
Sherr, C.J.1
-
11
-
-
0034818446
-
Post-translational modifications and activation of p53 by genotoxic stresses
-
Appella E., and Anderson C.W. Post-translational modifications and activation of p53 by genotoxic stresses. Eur J Biochem 268 (2001) 2764-2772
-
(2001)
Eur J Biochem
, vol.268
, pp. 2764-2772
-
-
Appella, E.1
Anderson, C.W.2
-
12
-
-
0035694469
-
Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases
-
Barlev N.A., Liu L., Chehab N.H., Mansfield K., Harris K.G., Halazonetis T.D., et al. Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases. Mol Cell 8 (2001) 1243-1254
-
(2001)
Mol Cell
, vol.8
, pp. 1243-1254
-
-
Barlev, N.A.1
Liu, L.2
Chehab, N.H.3
Mansfield, K.4
Harris, K.G.5
Halazonetis, T.D.6
-
13
-
-
0033609306
-
Mutations in serines 15 and 20 of human p53 impair its apoptotic activity
-
Unger T., Sionov R.V., Moallem E., Yee C.L., Howley P.M., Oren M., et al. Mutations in serines 15 and 20 of human p53 impair its apoptotic activity. Oncogene 18 (1999) 3205-3212
-
(1999)
Oncogene
, vol.18
, pp. 3205-3212
-
-
Unger, T.1
Sionov, R.V.2
Moallem, E.3
Yee, C.L.4
Howley, P.M.5
Oren, M.6
-
14
-
-
0033119627
-
Critical role for Ser20 of human p53 in the negative regulation of p53 by MDM-2
-
Unger T., Juven-Gershon T., Moallem E., Berger M., Vogt Sionov R., Lozano G., et al. Critical role for Ser20 of human p53 in the negative regulation of p53 by MDM-2. Embo J 18 (1999) 1805-1814
-
(1999)
Embo J
, vol.18
, pp. 1805-1814
-
-
Unger, T.1
Juven-Gershon, T.2
Moallem, E.3
Berger, M.4
Vogt Sionov, R.5
Lozano, G.6
-
15
-
-
0142039901
-
Cell type- and promoter-specific roles of Ser18 phosphorylation in regulating p53 responses
-
Chao C., Hergenhahn M., Kaeser M.D., Wu Z., Saito S., Iggo R., et al. Cell type- and promoter-specific roles of Ser18 phosphorylation in regulating p53 responses. J Biol Chem 278 (2003) 41028-41033
-
(2003)
J Biol Chem
, vol.278
, pp. 41028-41033
-
-
Chao, C.1
Hergenhahn, M.2
Kaeser, M.D.3
Wu, Z.4
Saito, S.5
Iggo, R.6
-
16
-
-
24344448786
-
p53 isoforms can regulate p53 transcriptional activity
-
Bourdon J.C., Fernandes K., Murray-Zmijewski F., Liu G., Diot A., Xirodimas D.P., et al. p53 isoforms can regulate p53 transcriptional activity. Genes Dev 19 (2005) 2122-2137
-
(2005)
Genes Dev
, vol.19
, pp. 2122-2137
-
-
Bourdon, J.C.1
Fernandes, K.2
Murray-Zmijewski, F.3
Liu, G.4
Diot, A.5
Xirodimas, D.P.6
-
17
-
-
0032980264
-
FASAY: a simple functional assay in yeast for identification of p53 mutation in tumors
-
Smardova J. FASAY: a simple functional assay in yeast for identification of p53 mutation in tumors. Neoplasma 46 (1999) 80-88
-
(1999)
Neoplasma
, vol.46
, pp. 80-88
-
-
Smardova, J.1
-
18
-
-
33644823574
-
Analysis of p53 status in human cell lines using a functional assay in yeast: detection of new non-sense p53 mutation in codon 124
-
Smardova J., Pavlova S., Svitakova M., Grochova D., and Ravcukova B. Analysis of p53 status in human cell lines using a functional assay in yeast: detection of new non-sense p53 mutation in codon 124. Oncol Rep 14 (2005) 901-907
-
(2005)
Oncol Rep
, vol.14
, pp. 901-907
-
-
Smardova, J.1
Pavlova, S.2
Svitakova, M.3
Grochova, D.4
Ravcukova, B.5
-
19
-
-
14044251523
-
The C terminus of p53 family proteins is a cell fate determinant
-
Harms K.L., and Chen X. The C terminus of p53 family proteins is a cell fate determinant. Mol Cell Biol 25 (2005) 2014-2030
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2014-2030
-
-
Harms, K.L.1
Chen, X.2
-
20
-
-
0036498543
-
Splicing regulation as a potential genetic modifier
-
Nissim-Rafinia M., and Kerem B. Splicing regulation as a potential genetic modifier. Trends Genet 18 (2002) 123-127
-
(2002)
Trends Genet
, vol.18
, pp. 123-127
-
-
Nissim-Rafinia, M.1
Kerem, B.2
-
21
-
-
22144463164
-
A novel human p53 isoform is an essential element of the ATR-intra-S phase checkpoint
-
Rohaly G., Chemnitz J., Dehde S., Nunez A.M., Heukeshoven J., Deppert W., et al. A novel human p53 isoform is an essential element of the ATR-intra-S phase checkpoint. Cell 122 (2005) 21-32
-
(2005)
Cell
, vol.122
, pp. 21-32
-
-
Rohaly, G.1
Chemnitz, J.2
Dehde, S.3
Nunez, A.M.4
Heukeshoven, J.5
Deppert, W.6
-
22
-
-
33846568870
-
Expression of p53 isoforms in squamous cell carcinoma of the head and neck
-
Boldrup L., Bourdon J.C., Coates P.J., Sjostrom B., and Nylander K. Expression of p53 isoforms in squamous cell carcinoma of the head and neck. Eur J Cancer 43 (2007) 617-623
-
(2007)
Eur J Cancer
, vol.43
, pp. 617-623
-
-
Boldrup, L.1
Bourdon, J.C.2
Coates, P.J.3
Sjostrom, B.4
Nylander, K.5
-
23
-
-
33751019470
-
Expression of C-terminal deleted p53 isoforms in neuroblastoma
-
Goldschneider D., Horvilleur E., Plassa L.F., Guillaud-Bataille M., Million K., Wittmer-Dupret E., et al. Expression of C-terminal deleted p53 isoforms in neuroblastoma. Nucleic Acids Res 34 (2006) 5603-5612
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 5603-5612
-
-
Goldschneider, D.1
Horvilleur, E.2
Plassa, L.F.3
Guillaud-Bataille, M.4
Million, K.5
Wittmer-Dupret, E.6
-
24
-
-
23644432376
-
The splicing machinery is a genetic modifier of disease severity
-
Nissim-Rafinia M., and Kerem B. The splicing machinery is a genetic modifier of disease severity. Trends Genet 21 (2005) 480-483
-
(2005)
Trends Genet
, vol.21
, pp. 480-483
-
-
Nissim-Rafinia, M.1
Kerem, B.2
-
25
-
-
0037816165
-
Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis
-
Kato S., Han S.Y., Liu W., Otsuka K., Shibata H., Kanamaru R., et al. Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis. Proc Natl Acad Sci USA 100 (2003) 8424-8429
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8424-8429
-
-
Kato, S.1
Han, S.Y.2
Liu, W.3
Otsuka, K.4
Shibata, H.5
Kanamaru, R.6
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