메뉴 건너뛰기




Volumn 368, Issue 3, 2008, Pages 729-735

Genetic impairment of autophagy intensifies expanded polyglutamine toxicity in Caenorhabditis elegans

Author keywords

Autophagy; C. elegans; Polyglutamine; RNAi

Indexed keywords

POLYGLUTAMINE;

EID: 39749114348     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.01.150     Document Type: Article
Times cited : (17)

References (24)
  • 1
    • 33745023775 scopus 로고    scopus 로고
    • Chaperone mediated autophagy in aging and disease
    • Massey A.C., Zhang C., and Cuervo A.M. Chaperone mediated autophagy in aging and disease. Curr. Top. Dev. Biol. 73 (2006) 205-235
    • (2006) Curr. Top. Dev. Biol. , vol.73 , pp. 205-235
    • Massey, A.C.1    Zhang, C.2    Cuervo, A.M.3
  • 2
    • 33847652900 scopus 로고    scopus 로고
    • Autophagy and neurodegeneration: when the cleaning crew goes on strike
    • Martinez-Vecente M., and Cuervo A.M. Autophagy and neurodegeneration: when the cleaning crew goes on strike. Lancet Neurol. 6 (2007) 352-361
    • (2007) Lancet Neurol. , vol.6 , pp. 352-361
    • Martinez-Vecente, M.1    Cuervo, A.M.2
  • 4
    • 33747881231 scopus 로고    scopus 로고
    • Autophagy in neurodegenerative disease: friend, foe or turncoat?
    • Nixon R.A. Autophagy in neurodegenerative disease: friend, foe or turncoat?. Trends Neurosci. 18 Jul (2006)
    • (2006) Trends Neurosci. , vol.18 , Issue.Jul
    • Nixon, R.A.1
  • 5
    • 0037194897 scopus 로고    scopus 로고
    • Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders
    • Ross C.A. Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders. Neuron 35 (2002) 819-822
    • (2002) Neuron , vol.35 , pp. 819-822
    • Ross, C.A.1
  • 6
    • 25844487226 scopus 로고    scopus 로고
    • Diseases of unstable repeat expansion: mechanisms and common principles
    • Gatchel J.R., and Zoghbi H.Y. Diseases of unstable repeat expansion: mechanisms and common principles. Nat. Rev. Genet. 6 (2005) 743-755
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 743-755
    • Gatchel, J.R.1    Zoghbi, H.Y.2
  • 7
    • 0033071176 scopus 로고    scopus 로고
    • Protein fate in neurodegenerative proteinopathies: polyglutamine diseases join the misfold
    • Paulson H.L. Protein fate in neurodegenerative proteinopathies: polyglutamine diseases join the misfold. Am. J. Hum. Genet. 64 (1999) 339-345
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 339-345
    • Paulson, H.L.1
  • 8
    • 33746487396 scopus 로고    scopus 로고
    • Expanded polyglutamines impair synaptic transmission and ubiquitin-proteasome system in Caenorhabditis elegans
    • Khan L.A., Bauer P.O., Miyazaki H., Lindenberg K.S., Landwehrmeyer B.G., et al. Expanded polyglutamines impair synaptic transmission and ubiquitin-proteasome system in Caenorhabditis elegans. J. Neurochem. 98 (2006) 576-587
    • (2006) J. Neurochem. , vol.98 , pp. 576-587
    • Khan, L.A.1    Bauer, P.O.2    Miyazaki, H.3    Lindenberg, K.S.4    Landwehrmeyer, B.G.5
  • 9
    • 0029047109 scopus 로고
    • Correlation between CAG repeat length and clinical features in Machado-Joseph disease
    • Maciel P., Gasper C., DeStefano A.L., Silveira I., Coutinho P., et al. Correlation between CAG repeat length and clinical features in Machado-Joseph disease. Am. J .Hum. Genet. 57 (1995) 54-61
    • (1995) Am. J .Hum. Genet. , vol.57 , pp. 54-61
    • Maciel, P.1    Gasper, C.2    DeStefano, A.L.3    Silveira, I.4    Coutinho, P.5
  • 10
    • 0028143527 scopus 로고
    • CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1
    • Kawaguchi Y., Okamoto T., Taniwaki M., Aizawa M., Inoue M., et al. CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1. Nature Genet. 8 (1994) 221-228
    • (1994) Nature Genet. , vol.8 , pp. 221-228
    • Kawaguchi, Y.1    Okamoto, T.2    Taniwaki, M.3    Aizawa, M.4    Inoue, M.5
  • 11
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S. The genetics of Caenorhabditis elegans. Genetics 77 (1974) 71-94
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 12
    • 0027451263 scopus 로고
    • Sequence requirements for myosin gene expression and regulation in Caenorhabditis elegans
    • Okkema P.G., Harrison S.W., Plunger V., Aryana A., and Fire A. Sequence requirements for myosin gene expression and regulation in Caenorhabditis elegans. Genetics 135 (1993) 385-404
    • (1993) Genetics , vol.135 , pp. 385-404
    • Okkema, P.G.1    Harrison, S.W.2    Plunger, V.3    Aryana, A.4    Fire, A.5
  • 13
    • 0025002190 scopus 로고
    • A modular set of LacZ fusion vectors for studying gene expression in Caenorhabditis elegans
    • Fire A., Harrison S., and Dixon D. A modular set of LacZ fusion vectors for studying gene expression in Caenorhabditis elegans. Gene 93 (1990) 189-198
    • (1990) Gene , vol.93 , pp. 189-198
    • Fire, A.1    Harrison, S.2    Dixon, D.3
  • 14
    • 23444431611 scopus 로고
    • Green fluorescent protein as a marker for gene expression
    • Chalfie M., Tu Y., Euskirchen G., Ward W.W., and Prasher D.C. Green fluorescent protein as a marker for gene expression. Science 263 (1994) 802-805
    • (1994) Science , vol.263 , pp. 802-805
    • Chalfie, M.1    Tu, Y.2    Euskirchen, G.3    Ward, W.W.4    Prasher, D.C.5
  • 15
    • 0035229245 scopus 로고    scopus 로고
    • R.S. Kamath, M. Martinez-Campos, P. Zipperlen, A.G. Fraser, J. Ahringer, Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans, Genome Biol. 2 (2001) RESEARCH0002.
    • R.S. Kamath, M. Martinez-Campos, P. Zipperlen, A.G. Fraser, J. Ahringer, Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans, Genome Biol. 2 (2001) RESEARCH0002.
  • 16
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: molecular mechanisms and biological functions of autophagy
    • Levine B., and Klionsky D.J. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev. Cell 4 (2004) 463-477
    • (2004) Dev. Cell , vol.4 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 17
    • 2342497702 scopus 로고    scopus 로고
    • Molecular and functional analysis of Caenorhabditis elegans CHIP, a homologue of Mammalian CHIP
    • Khan L.A., and Nukina N. Molecular and functional analysis of Caenorhabditis elegans CHIP, a homologue of Mammalian CHIP. FEBS Lett. 565 (2004) 11-18
    • (2004) FEBS Lett. , vol.565 , pp. 11-18
    • Khan, L.A.1    Nukina, N.2
  • 18
    • 0042691506 scopus 로고    scopus 로고
    • Autophagy genes are essential for dauer development and life-span extension in C. elegans
    • Melendez A., Talloczy Z., Seaman M., Eskelinen E.L., Hall D.H., et al. Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 301 (2003) 1387-1391
    • (2003) Science , vol.301 , pp. 1387-1391
    • Melendez, A.1    Talloczy, Z.2    Seaman, M.3    Eskelinen, E.L.4    Hall, D.H.5
  • 19
    • 8344242220 scopus 로고    scopus 로고
    • Autophagy in health and disease: a double-edged sword
    • Shintani T., and Klionsky D.J. Autophagy in health and disease: a double-edged sword. Science 306 (2004) 990-995
    • (2004) Science , vol.306 , pp. 990-995
    • Shintani, T.1    Klionsky, D.J.2
  • 20
    • 0037015269 scopus 로고    scopus 로고
    • TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation
    • Long X., Spycher C., Han Z.S., Rose A.M., Muller F., et al. TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation. Curr. Biol. 12 (2002) 1448-1461
    • (2002) Curr. Biol. , vol.12 , pp. 1448-1461
    • Long, X.1    Spycher, C.2    Han, Z.S.3    Rose, A.M.4    Muller, F.5
  • 21
    • 4544311861 scopus 로고    scopus 로고
    • The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
    • Jia K., Chen D., and Riddle D.L. The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 131 (2004) 3897-3906
    • (2004) Development , vol.131 , pp. 3897-3906
    • Jia, K.1    Chen, D.2    Riddle, D.L.3
  • 22
    • 1842766144 scopus 로고    scopus 로고
    • Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins
    • Venkatraman P., Wetzel R., Tanaka M., Nukina N., and Goldberg A.L. Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins. Mol. Cell 14 (2004) 95-104
    • (2004) Mol. Cell , vol.14 , pp. 95-104
    • Venkatraman, P.1    Wetzel, R.2    Tanaka, M.3    Nukina, N.4    Goldberg, A.L.5
  • 23
    • 2642586352 scopus 로고    scopus 로고
    • Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
    • Ravikumar B., Vacher C., Berger Z., Davies J.E., Luo S., et al. Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease. Nat. Genet. 36 (2004) 585-595
    • (2004) Nat. Genet. , vol.36 , pp. 585-595
    • Ravikumar, B.1    Vacher, C.2    Berger, Z.3    Davies, J.E.4    Luo, S.5
  • 24
    • 33846210657 scopus 로고    scopus 로고
    • Autophagy genes protect against disease caused by polyglutamine expansion proteins in Caenorhabditis elegans
    • Jia K., Hart A.C., and Levine B. Autophagy genes protect against disease caused by polyglutamine expansion proteins in Caenorhabditis elegans. Autophagy 3 (2007) 21-25
    • (2007) Autophagy , vol.3 , pp. 21-25
    • Jia, K.1    Hart, A.C.2    Levine, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.