Gc-globulin (vitamin D binding protein) is synthesized and secreted by hepatocytes and internalized by hepatic stellate cells through Ca2+-dependent interaction with the megalin/gp330 receptor

Clinica Chimica Acta

Volumn 390, Issue 1-2, 2008, Pages 28-37

  Gressner, Olav A ^a   Lahme, Birgit ^a   Gressner, Axel M ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

smooth muscle actin filaments; Calcium; Gc globulin; Hepatic stellate cells; Hepatocytes; Megalin gp330 receptor

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CALCIUM ION; COLLAGENASE; CUBILIN; CYCLOHEXIMIDE; HERMES ANTIGEN; LIPOCORTIN 2; MEGALIN; NEUTRALIZING ANTIBODY; PRONASE; VITAMIN D; VITAMIN D BINDING PROTEIN;

ARTICLE; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CELL TYPE; CHEMICAL INTERACTION; CONTROLLED STUDY; CYTOSKELETON; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; INTERNALIZATION; LIVER CELL; MYOFIBROBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; RECEPTOR BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STELLATE CELL; VITAMIN D METABOLISM;

ANIMALS; BASE SEQUENCE; CALCIUM; CELLS, CULTURED; DNA PRIMERS; HEPATOCYTES; IMMUNOPRECIPITATION; LDL-RECEPTOR RELATED PROTEIN 2; MALE; MICROSCOPY, FLUORESCENCE; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; VITAMIN D-BINDING PROTEIN;

EID: 39649115805     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2007.12.011     Document Type: Article

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