Proneural bHLH neurogenin 2 differentially regulates Nurr1-induced dopamine neuron differentiation in rat and mouse neural precursor cells in vitro

FEBS Letters

Volumn 582, Issue 5, 2008, Pages 537-542

  Park, Chang Hwan ^a   Kang, Jin Sun ^a   Yoon, Eun Hye ^a   Shim, Jae Won ^a   Suh Kim, Haeyoung ^b   Lee, Sang Hun ^a  

^a Hanyang University   (South Korea)

^b Ajou University   (South Korea)

Author keywords

Dopaminergic differentiation; Neural precursor cells; Neurogenin 2; Nurr1; Species dependent differences

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; DOPAMINE; NEUROGENIN 2; NUCLEAR RECEPTOR RELATED FACTOR 1; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; IN VITRO STUDY; MESENCEPHALON; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; DOPAMINE; GENE EXPRESSION REGULATION; HUMANS; MICE; NERVE TISSUE PROTEINS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY; STEM CELLS; TRANSCRIPTION FACTORS; TYROSINE 3-MONOOXYGENASE;

EXOGENE; RATTUS;

EID: 39649113551     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.01.018     Document Type: Article

References (23)

1. Zetterstrom R.H., Solomin L., Jansson L., Hoffer B.J., Olson L., and Perlmann T. Dopamine neuron agenesis in Nurr1-deficient mice. Science 276 (1997) 248-250
2. Baffi J.S., Palkovits M., Castillo S.O., Mezey E., and Nikodem V.M. Differential expression of tyrosine hydroxylase in catecholaminergic neurons of neonatal wild-type and Nurr1-deficient mice. Neuroscience 93 (1999) 631-642
3. Le W., Conneely O.M., Zou L., He Y., Saucedo-Cardenas O., Jankovic J., Mosier D.R., and Appel S.H. Selective agenesis of mesencephalic dopaminergic neurons in Nurr1-deficient mice. Exp. Neurol. 159 (1999) 451-458
4. Kim J.Y., Koh H.C., Lee J.Y., Chang M.Y., Kim Y.C., Chung H.Y., Son H., Lee Y.S., Studer L., McKay R., and Lee S.H. Dopaminergic neuronal differentiation from rat embryonic neural precursors by Nurr1 overexpression. J. Neurochem. 85 6 (2003) 1443-1454
5. Sonntag K.C., Simantov R., Kim K.S., and Isacson O. Temporally induced Nurr1 can induce a non-neuronal dopaminergic cell type in embryonic stem cell differentiation. Eur. J. Neurosci. 19 5 (2004) 1141-1152
6. Sakurada K., Ohshima-Sakurada M., Palmer T.D., and Gage F.H. Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain. Development 126 18 (1999) 4017-4026
7. Kageyama R., and Nakanishi S. Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system. Curr. Opin. Genet. Dev. 7 (1997) 659-665
8. Kele J., Simplicio N., Ferri A.L., Mira H., Guillemot F., Arenas E., and Ang S.L. Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons. Development 133 (2006) 495-505
9. Andersson E., Jensen J.B., Parmar M., Guillemot F., and Bjorklund A. Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2. Development 133 (2006) 507-516
10. Park C.H., Kang J.S., Kim J.S., Chung S., Koh J.Y., Yoon E.H., Jo A.Y., Chang M.Y., Koh H.C., Hwang H., Suh-Kim S., Lee Y.S., Kim K.S., and Lee S.H. Differential actions of the proneural genes Mash1 and Neurogenins in Nurr1-induced dopamine neuron differentiation. J. Cell Sci. 119 (2006) 2310-2320
11. Park C.H., Kang J.S., Shin Y.H., Chang M.Y., Chung S., Koh H.C., Zhu M.H., Oh S.B., Lee Y.S., Panagiotakos G., Tabar V., Studer L., and Lee S.H. Acquisition of in vitro and in vivo functionality of Nurr1-induced dopamine neurons. FASEB J. 20 14 (2006) 2553-2555
12. Johe K.K., Hazel T.G., Muller T., Dugich-Djordjevic M.M., and McKay R.D. Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Gene Dev. 15 (1996) 3129-3140
13. Shim J.W., Park C.H., Bae Y.C., Bae J.Y., Chung S., Chang M.Y., Koh H.C., Lee H.S., Hwang S.J., Lee K.H., Lee Y.S., Choi C.Y., and Lee S.H. Generation of functional dopamine neurons from neural precursor cells isolated from the subventricular zone and white matter of the adult rat brain using Nurr1 overexpression. Stem Cell 25 (2007) 1252-1262
14. Wagner J., Akerud P., Castro D.S., Holm P.C., Canals J.M., Snyder E.Y., Perlmann T., and Arenas E. Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes. Nat. Biotech. 17 (1999) 653-659
15. Castelo-Branco G., Sousa K.M., Bryja V., Pinto L., Wagner J., and Arenas E. Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion. Mol. Cell. Neurosci. 31 (2006) 251-262
16. Ko J.Y., Lee J.Y., Park C.H., and Lee S.H. Effect of Cell-density on in vitro dopaminergic differentiation of mesencephalic precursor cells. Neuroreport 16 (2005) 499-503
17. Bertrand N., Castro D.S., and Guillemot F. Proneural genes and the specification of neural cell types. Nat. Rev. Neurosci. 3 (2002) 517-530
18. Andersson E.K.I., Irvin D.K., Ahlsiö J., and Parmar M. Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells. Exp. Cell. Res. 313 (2007) 1172-1180
19. Yan J., Studer L., and McKay R.D.G. Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors. J. Neurochem. 76 (2001) 307-311
20. Chang M.Y., Park C.H., Lee S.Y., and Lee S.H. Properties of cortical precursor cells cultured long term are similar to those of precursors at later developmental stages. Dev. Brain Res. 153 (2004) 89-96
21. Jo A.Y., Park C.H., Aizawa S., and Lee S.H. Contrasting and brain region-specific roles of neurogenin 2 and Mash1 in GABAergic neuron differentiation in vitro. Exp. Cell. Res. 313 (2007) 4066-4081
22. Ray J., and Gage F.H. Differential properties of adult rat and mouse brain-derived neural stem/progenitor cells. Mol. Cell. Neurosci. 31 (2006) 560-573
23. Jin H., Romano G., Marshall C., Donaldson A.E., Suon S., and Iacovitti L. Tyrosine hydroxylase gene regulation in human neuronal progenitor cells does not depend on Nurr1 as in the murine and rat systems. J. Cell. Physiol. 207 (2006) 49-57