Differential expression of tyrosine hydroxylase in catecholaminergic neurons of neonatal wild-type and nurr1-deficient mice

Neuroscience

Volumn 93, Issue 2, 1999, Pages 631-642

  Baffi, J S ^a   Palkovits, M ^a   Castillo, S O ^a   Mezey, E ^a   Nikodem, V M ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Catecholaminergic cell groups; Central nervous system; In situ hybridization; Nurr1; Orphan nuclear receptor; Tyrosine hydroxylase

Indexed keywords

CELL NUCLEUS RECEPTOR; DOPAMINE; MESSENGER RNA; TRANSCRIPTION FACTOR; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATECHOLAMINE NERVE CELL; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; IMMUNOREACTIVITY; IN SITU HYBRIDIZATION; MOUSE; MUTANT; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRAIN DIFFERENCE; SUBSTANTIA NIGRA; TEGMENTUM;

ANIMALS; ANIMALS, NEWBORN; BRAIN CHEMISTRY; CATECHOLAMINES; DNA-BINDING PROTEINS; DOPAMINE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; IN SITU HYBRIDIZATION; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEURONS; NOREPINEPHRINE; RNA, MESSENGER; TRANSCRIPTION FACTORS; TYROSINE 3-MONOOXYGENASE;

EID: 0032801303     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(99)00124-4     Document Type: Article

References (26)

1. Beato M., Herrlich P., Schutz G. Steroid hormone receptors: many actors in search of a plot. Cell. 83:1995;851-857.
2. Bradley D.J., Young W.S.d., Weinberger C. Differential expression of alpha and beta thyroid hormone receptor genes in rat brain and pituitary. Proc. natn. Acad. Sci. U.S.A. 86:1989;7250-7254.
3. Castillo S.O., Baffi J.S., Palkovits M., Goldstein D.S., Kopin I.J., Witta J., Magnuson M.A., Nikodem V.M. Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene. Molec. cell. Neurosci. 11:1998;36-46.
4. Castillo S.O., Xiao Q., Lyu M.S., Kozak C.A., Nikodem V.M. Organization, sequence, chromosomal localization and promoter identification of the mouse orphan nuclear receptor Nurr1 gene. Genomics. 41:1997;250-257.
5. Dahlström A., Fuxe K. Localization of monoamines in the lower brain stem. Experientia. 20:1964;398-399.
6. Evan R.M. The steroid and thyroid hormone receptor superfamily. Science. 240:1988;889-895.
7. Kalia M., Fuxe K., Goldstein M. Rat medulla oblongata. II. Dopaminergic, noradrenergic (A1 and A2) and adrenergic neurons, nerve fibers, and presumptive terminal processes. J. comp. Neurol. 233:1985;308-332.
8. Kastner P., Mark M., Chambon P. Nonsteroid nuclear receptors: what are genetics studies telling us about their role in real life? Cell. 83:1995;859-870.
9. Konig N., Wilkie M.B., Lauder J.M. Tyrosine hydroxylase and serotonin containing cells in embryonic rat rhombencephalon: a whole-mount immunocytochemical study. J. Neurosci. Res. 20:1988;212-223.
10. Law S.W., Conneely O.M., DeMayo F.J., O'Malley B.W. Identification of a new brain-specific transcription factor, NURR1. Molec. Endocrinol. 6:1992;2129-2135.
11. Le Moine C., Young W.S.d. RHS2, a POU domain-containing gene, and its expression in developing and adult rat. Proc. natn. Acad. Sci. U.S.A. 89:1992;3285-3289.
12. Mages H.W., Rilke O., Bravo R., Senger G., Kroczek R.A. NOT, a human immediate-early response gene closely related to the steroid/thyroid hormone receptor NAK1/TR3. Molec. Endocrinol. 8:1994;1583-1591.
13. Okabe T., Takayanagi R., Imasaki K., Haji M., Nawata H., Watanabe T. cDNA cloning of a NGFI-B/nur77-related transcription factor from an apoptotic human T cell line. J. Immunol. 154:1995;3871-3879.
14. O'Malley B.W., Conneely O.M. Orphan receptors: in search of a unifying hypothesis for activation. Molec. Endocrinol. 6:1992;1359-1361.
15. Pena de Ortiz S., Cannon M.M., Jamieson G.A. Jr. Expression of nuclear hormone receptors within the rat hippocampus: identification of novel orphan receptors. Molec. Brain Res. 23:1994;278-283.
16. Saucedo-Cardenas O., Conneely O.M. Comparative distribution of NURR1 and NUR77 nuclear receptors in the mouse central nervous system. J. molec. Neurosci. 7:1996;51-63.
17. Saucedo-Cardenas O., Quintana-Hau J., Le W., Smidt M., Cox J., De Mayo F., Burbach J., Conneely O. Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic presursor neurons. Proc. natn. Acad. Sci. U.S.A. 95:1998;4013-4018.
18. Scearce L.M., Laz T.M., Hazel T.G., Lau L.F., Taub R. RNR-1, a nuclear receptor in the NGFI-B/Nur77 family that is rapidly induced in regenerating liver. J. biol. Chem. 268:1993;8855-8861.
19. Solberg Y., Pollack Y., Silverman W.F. Differential expression of tyrosine hydroxylase mRNA in the developing rat mesencephalon. Cell. molec. Neurobiol. 12:1992;569-580.
20. Thummel C.S. From embryogenesis to metamorphosis: the regulation and function of Drosophila nuclear receptor superfamily members. Cell. 83:1995;871-877.
21. Xiao Q., Castillo S.O., Nikodem V.M. Distribution of messenger RNAs for the orphan nuclear receptors Nurr1 and Nur77 (NGFI-B) in adult rat brain by in situ hybridization. Neuroscience. 75:1996;221-230.
22. Ye W., Shimamura K., Rubenstein J., Hynes M., Rosenthal A. FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell. 93:1998;755-766.
23. Zetterström R.H., Solomin L., Jansson L., Hoffer B.J., Olson L., Perlmann T. Dopamine neuron agenesis in Nurr1-deficient mice. Science. 276:1997;248-250.
24. Zetterström R.H., Solomin L., Matsiadis T., Olson L., Perlmann T. Retinoid X Receptor heterodimerization and developmental expression distinguish the orphan nuclear receptors NGFI-B, Nurr1, and Nor1. Molec. Endocrinol. 10:1996;1656-1666.
25. Zetterström R.H., Williams R., Perlmann T., Olson L. Cellular expression of the immediate early transcription factor Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system. Molec. Brain Res. 41:1996;111-120.
26. Zhou Q.-Y., Palmiter R.D. Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic. Cell. 83:1995;1197-1209.