Molecular determinants of the anticonvulsant felbamate binding site in the N-methyl-D-aspartate receptor

Journal of Medicinal Chemistry

Volumn 51, Issue 6, 2008, Pages 1534-1545

  Chang, Huai Ren ^a   Kuo, Chung Chin ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ANTICONVULSIVE AGENT; FELBAMATE; MUTANT PROTEIN; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN SUBUNIT;

ANIMAL CELL; ANTICONVULSANT ACTIVITY; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DRUG BINDING; DRUG INHIBITION; ELECTROPHYSIOLOGY; MOLECULAR CLONING; NONHUMAN; PROTEIN FOLDING; PROTEIN MODIFICATION; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; VESTIBULE AQUEDUCT;

ANIMALS; ANTICONVULSANTS; BINDING SITES; BINDING, COMPETITIVE; CELLS, CULTURED; CLONING, MOLECULAR; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; GENE EXPRESSION REGULATION; ION CHANNEL GATING; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PHENYLCARBAMATES; PROPYLENE GLYCOLS; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS;

EID: 39649107253     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0706618     Document Type: Article

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