Dynamics of granzyme B-induced apoptosis: Mathematical modeling

Mathematical Biosciences

Volumn 212, Issue 1, 2008, Pages 54-68

  Golovchenko, Evdokia N ^a   Hanin, Leonid G ^b   Kaufmann, Scott H ^c   Tyurin, Kirill V ^d   Khanin, Mikhail A ^d  

^a INSTITUTE OF MATHEMATICAL MODELING   (Russian Federation)

^b Nucl Eng Idaho State University   (United States)

^c MAYO CLINIC   (United States)

^d CENTER FOR THEORETICAL PROBLEMS OF PHYSICOCHEMICAL PHARMACOLOGY   (Russian Federation)

Author keywords

Apoptosis; Caspase activation; Granzyme B; Mathematical modeling

Indexed keywords

CELL DEATH; MATHEMATICAL MODELS; MOLECULAR DYNAMICS; OPTIMIZATION; PROBLEM SOLVING;

GRANZYME B; MITOCHONDRIAL INTERMEMBRANE SPACE;

ENZYME KINETICS;

GRANZYME B; PROCASPASE 3;

APOPTOSIS; BIOCHEMISTRY; ENZYME ACTIVITY; KINETICS; NUMERICAL MODEL; PROTEIN;

APOPTOSIS; ARTICLE; CELL STRAIN K 562; DYNAMICS; ENZYME ACTIVATION; ENZYME KINETICS; HUMAN; HUMAN CELL; MATHEMATICAL MODEL; PROTEIN INTAKE;

APOPTOSIS; GRANZYMES; HUMANS; K562 CELLS; MODELS, BIOLOGICAL;

EID: 39649105002     PISSN: 00255564     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mbs.2007.12.002     Document Type: Article

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