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Volumn 33, Issue 1-2, 2007, Pages 57-66

A perspective of pemphigus from bedside and laboratory-bench

Author keywords

Desmogleins; Desmosomes; Pemphigus; Signaling

Indexed keywords

DESMOGLEIN; DESMOGLEIN 1 ANTIBODY; DESMOGLEIN 3 ANTIBODY; IMMUNOGLOBULIN G; AUTOANTIBODY; DESMOGLEIN 1; DESMOGLEIN 3;

EID: 39649101736     PISSN: 10800549     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12016-007-0036-5     Document Type: Review
Times cited : (26)

References (64)
  • 1
    • 33644769923 scopus 로고    scopus 로고
    • Inherited disorders of desmosomes
    • MacGrath JA (2005) Inherited disorders of desmosomes. Aust J Dermatol 46:221-229
    • (2005) Aust J Dermatol , vol.46 , pp. 221-229
    • MacGrath, J.A.1
  • 2
    • 0036454873 scopus 로고    scopus 로고
    • Mechanisms of desmosome assembly and disassembly
    • Kitajima Y (2002) Mechanisms of desmosome assembly and disassembly. Clin Exp Dermatol 27:684-690
    • (2002) Clin Exp Dermatol , vol.27 , pp. 684-690
    • Kitajima, Y.1
  • 3
    • 0027301255 scopus 로고
    • Cell adhesion molecules as targets of autoantibodies in pemphigus and pemphigoid, bullous diseases due to defective epidermal cell adhesion. Advances in immunology
    • Stanley JR (1992) Cell adhesion molecules as targets of autoantibodies in pemphigus and pemphigoid, bullous diseases due to defective epidermal cell adhesion. Advances in immunology. Adv Immunol 53:291-325
    • (1992) Adv Immunol , vol.53 , pp. 291-325
    • Stanley, J.R.1
  • 4
    • 0033010864 scopus 로고    scopus 로고
    • Autoimmunity against desmosomal cadherins in pemphigus
    • Amagai M (1999) Autoimmunity against desmosomal cadherins in pemphigus. J Dermatol Sci 20:92-102
    • (1999) J Dermatol Sci , vol.20 , pp. 92-102
    • Amagai, M.1
  • 5
    • 0037622122 scopus 로고    scopus 로고
    • Current and prospective understanding of clinical classification, pathomechanisms and therapy in pemphigus
    • Kitajima Y (2003) Current and prospective understanding of clinical classification, pathomechanisms and therapy in pemphigus. Arch Dermatol Res 295:S17-S23
    • (2003) Arch Dermatol Res , vol.295
    • Kitajima, Y.1
  • 8
    • 0029705413 scopus 로고    scopus 로고
    • Pemphigus: Autoimmunity to epidermal cell adhesion molecules
    • Amagai M (1996) Pemphigus: autoimmunity to epidermal cell adhesion molecules. Adv Dermatol 11:319-352
    • (1996) Adv Dermatol , vol.11 , pp. 319-352
    • Amagai, M.1
  • 9
    • 0033557198 scopus 로고    scopus 로고
    • Explanations for the clinical and microscopic localization of lesions in pemphigus foliaceus and vulgaris
    • Mahoney MG, Wang Z, Rothenberger K, Koch PJ, Amagai M, Stanley JR (1999) Explanations for the clinical and microscopic localization of lesions in pemphigus foliaceus and vulgaris. J Clin Invest 103:461-468
    • (1999) J Clin Invest , vol.103 , pp. 461-468
    • Mahoney, M.G.1    Wang, Z.2    Rothenberger, K.3    Koch, P.J.4    Amagai, M.5    Stanley, J.R.6
  • 10
    • 0033710565 scopus 로고    scopus 로고
    • Toxin in bullous impetigo and staphylococcal scalded-skin syndrome targets desmoglein 1
    • Amagai M, Matsuyoshi N, Wang ZH, Andl C, Stanley JR (2000) Toxin in bullous impetigo and staphylococcal scalded-skin syndrome targets desmoglein 1. Nat Med 6:1275-1277
    • (2000) Nat Med , vol.6 , pp. 1275-1277
    • Amagai, M.1    Matsuyoshi, N.2    Wang, Z.H.3    Andl, C.4    Stanley, J.R.5
  • 11
    • 0029096566 scopus 로고
    • Conformational epitopes of pemphigus antigens (Dsg1 and Dsg3) are calcium dependent and glycosylation independent
    • Amagai M, Ishii K, Hashimoto T, Gamou S, Shimizu N, Nisshikawa T (1995) Conformational epitopes of pemphigus antigens (Dsg1 and Dsg3) are calcium dependent and glycosylation independent. J Invest Dermatol 105:243-247
    • (1995) J Invest Dermatol , vol.105 , pp. 243-247
    • Amagai, M.1    Ishii, K.2    Hashimoto, T.3    Gamou, S.4    Shimizu, N.5    Nisshikawa, T.6
  • 13
    • 14144253430 scopus 로고    scopus 로고
    • Paraneoplastic pemphigus: A brief update
    • Wade MS, Black MM (2005) Paraneoplastic pemphigus: a brief update. Aust J Dermatol 46:1-10
    • (2005) Aust J Dermatol , vol.46 , pp. 1-10
    • Wade, M.S.1    Black, M.M.2
  • 14
    • 0016693303 scopus 로고
    • Immunologic phenomena in herpes gestations. Their pathogenic and diagnostic significance
    • Jablonska S, Chorzelski TP, Beutner EH, Jarzabek-Chorzelsska M (1975) Immunologic phenomena in herpes gestations. Their pathogenic and diagnostic significance. J Dermatol 14:353-359
    • (1975) J Dermatol , vol.14 , pp. 353-359
    • Jablonska, S.1    Chorzelski, T.P.2    Beutner, E.H.3    Jarzabek-Chorzelsska, M.4
  • 16
    • 0023189992 scopus 로고
    • Intercellular IgA dermatosis with clinical features of subcorneal pustular dermatosis
    • Hashimoto T, Inamoto N, Nakamura K, Noishikawa T (1987) Intercellular IgA dermatosis with clinical features of subcorneal pustular dermatosis. Arch Dermatol 123:1062-1065
    • (1987) Arch Dermatol , vol.123 , pp. 1062-1065
    • Hashimoto, T.1    Inamoto, N.2    Nakamura, K.3    Noishikawa, T.4
  • 17
    • 8544279670 scopus 로고    scopus 로고
    • Human desmocollin 1 (Dsc1) is an autoantigen for the subcorneal pustular dermatosis type of IgA pemphigus
    • Hashimoto T, Kiyokawa C, Mori O, Miyasato M, Chidgey MA, Garrod DR (1997) Human desmocollin 1 (Dsc1) is an autoantigen for the subcorneal pustular dermatosis type of IgA pemphigus. J Invest Dermatol 109:127-131
    • (1997) J Invest Dermatol , vol.109 , pp. 127-131
    • Hashimoto, T.1    Kiyokawa, C.2    Mori, O.3    Miyasato, M.4    Chidgey, M.A.5    Garrod, D.R.6
  • 19
    • 4043060001 scopus 로고    scopus 로고
    • The detection of IgG and IgA autoantibodies to desmocollins 1-3 by enzyme-linked immunosorbent assays using baculovirus-expressed proteins, in atypical pemphigus but not in typical pemphigus
    • Hisamatsu Y, Amagai M, Garrod DR, Kanzaki T, Hashimoto T (2004) The detection of IgG and IgA autoantibodies to desmocollins 1-3 by enzyme-linked immunosorbent assays using baculovirus-expressed proteins, in atypical pemphigus but not in typical pemphigus. Br J Dermatol 151:73-83
    • (2004) Br J Dermatol , vol.151 , pp. 73-83
    • Hisamatsu, Y.1    Amagai, M.2    Garrod, D.R.3    Kanzaki, T.4    Hashimoto, T.5
  • 20
    • 0021349435 scopus 로고
    • Pemphigus vegetans. Neumann type and Hallopeau type
    • Ahmed AR, Blose DA (1984) Pemphigus vegetans. Neumann type and Hallopeau type. Int J Dermatol 23:135-141
    • (1984) Int J Dermatol , vol.23 , pp. 135-141
    • Ahmed, A.R.1    Blose, D.A.2
  • 21
    • 0037442123 scopus 로고    scopus 로고
    • Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3
    • Tsunoda K, Oita T, Aoki M, Yamada T, Nagai T, Nakagawa T, Koyasu S, Nishikawa T, Amagai M (2003) Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3. J Immunol 170:2170-2178
    • (2003) J Immunol , vol.170 , pp. 2170-2178
    • Tsunoda, K.1    Oita, T.2    Aoki, M.3    Yamada, T.4    Nagai, T.5    Nakagawa, T.6    Koyasu, S.7    Nishikawa, T.8    Amagai, M.9
  • 22
    • 0033838601 scopus 로고    scopus 로고
    • The distribution of pemphigus vulgaris-IgG subclasses and their reactivity with desmoglein 3 and 1 in pemphigus patients and their first-degree relatives
    • Kricheli D, David M -Zlotkin M, Goldsmith D, Rabinov M, Sulkes J, Milner Y (2000) The distribution of pemphigus vulgaris-IgG subclasses and their reactivity with desmoglein 3 and 1 in pemphigus patients and their first-degree relatives. Br J Dermatol 143:237-238
    • (2000) Br J Dermatol , vol.143 , pp. 237-238
    • Kricheli, D.1    Davidm, -Z.2    Goldsmith, M.3    Rabinov, D.4    Sulkes, M.5    Milner, J.6
  • 23
    • 0347087440 scopus 로고    scopus 로고
    • Pemphigus vulgaris antibody identifies pemphaxin. a novel keratinocyte annexin-like molecule binding acetylcholine
    • Nguyen VT, Arredondo J, Chernyavssky AI, Kitajima Y, Pittelkow M, Grando SA (2004) Pemphigus vulgaris antibody identifies pemphaxin. A novel keratinocyte annexin-like molecule binding acetylcholine. J Biol Chem 279:2135-2146
    • (2004) J Biol Chem , vol.279 , pp. 2135-2146
    • Nguyen, V.T.1    Arredondo, J.2    Chernyavssky, A.I.3    Kitajima, Y.4    Pittelkow, M.5    Grando, S.A.6
  • 24
    • 1542336471 scopus 로고    scopus 로고
    • The pathophysiological significance of nondesmoglein targets of pemphigus autoimmunity. Development of antibodies against keratinocyte cholinergic receptors in patients with pemphigus vulgaris and pemphigus foliaceus
    • Nguyen VT, Arredondo J, Chernyavssky AI, Pittelkow M, Kitajima Y, Grando SA (2004) The pathophysiological significance of nondesmoglein targets of pemphigus autoimmunity. Development of antibodies against keratinocyte cholinergic receptors in patients with pemphigus vulgaris and pemphigus foliaceus. Arch Dermatol 140:327-334
    • (2004) Arch Dermatol , vol.140 , pp. 327-334
    • Nguyen, V.T.1    Arredondo, J.2    Chernyavssky, A.I.3    Pittelkow, M.4    Kitajima, Y.5    Grando, S.A.6
  • 25
    • 0034519478 scopus 로고    scopus 로고
    • Antibodies against keratinocyte antigens other than desmogleins 1 and 3 can induce pemphigus vulgaris-like lesions
    • Nguyen VT, Ndoye A, Shultz LD, Pittelkow MR, Grando S (2000) Antibodies against keratinocyte antigens other than desmogleins 1 and 3 can induce pemphigus vulgaris-like lesions. J Clin Invest 106:1467-1479
    • (2000) J Clin Invest , vol.106 , pp. 1467-1479
    • Nguyen, V.T.1    Ndoye, A.2    Shultz, L.D.3    Pittelkow, M.R.4    Grando, S.5
  • 26
    • 0034703029 scopus 로고    scopus 로고
    • Pemphigus vulgaris antibody identifies pemphaxin. a novel keratinocyte annexin-like molecule binding acetylcholine
    • Nguyen VT, Ndoye A, Grando SA (2000) Pemphigus vulgaris antibody identifies pemphaxin. A novel keratinocyte annexin-like molecule binding acetylcholine. J Biol Chem 275:29466-29476
    • (2000) J Biol Chem , vol.275 , pp. 29466-29476
    • Nguyen, V.T.1    Ndoye, A.2    Grando, S.A.3
  • 27
    • 0034521463 scopus 로고    scopus 로고
    • Autoimmunity to keratinocyte acethylcholin receptors in pemphigus
    • Grando SA (2000) Autoimmunity to keratinocyte acethylcholin receptors in pemphigus. Dermatology 201:290-295
    • (2000) Dermatology , vol.201 , pp. 290-295
    • Grando, S.A.1
  • 28
    • 33644793144 scopus 로고    scopus 로고
    • Cholinergic control of epidermal cohesion
    • Grando SA (2006) Cholinergic control of epidermal cohesion. Exp Dermatol 15:265-287
    • (2006) Exp Dermatol , vol.15 , pp. 265-287
    • Grando, S.A.1
  • 30
    • 0032857374 scopus 로고    scopus 로고
    • Transmembrane signaling for adhesive regulation of desmosomes and hemidesmosomes, and for cell-cell detachment induced by pemphigus IgG in cultured keratinocytes: Involvement of protein kinase C
    • Kitajima Y, Aoyama Y, Seishima M (1999) Transmembrane signaling for adhesive regulation of desmosomes and hemidesmosomes, and for cell-cell detachment induced by pemphigus IgG in cultured keratinocytes: involvement of protein kinase C. J Invest Dermatol Symp Proc 4:137-144
    • (1999) J Invest Dermatol Symp Proc , vol.4 , pp. 137-144
    • Kitajima, Y.1    Aoyama, Y.2    Seishima, M.3
  • 31
    • 0030902370 scopus 로고    scopus 로고
    • Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris
    • Koch PJ, Mahoney MG, Ishikawa H, Pulkkinen L, Uitto J, Shultz L, Murphy GF, Whitaker-Menezes D, Stanley JR (1997) Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris. J Cell Biol 137:1091-1110
    • (1997) J Cell Biol , vol.137 , pp. 1091-1110
    • Koch, P.J.1    Mahoney, M.G.2    Ishikawa, H.3    Pulkkinen, L.4    Uitto, J.5    Shultz, L.6    Murphy, G.F.7    Whitaker-Menezes, D.8    Stanley, J.R.9
  • 33
    • 0033740182 scopus 로고    scopus 로고
    • The pathophysiology of pemphigus
    • Stanley JR (2000) The pathophysiology of pemphigus. J Dermatol Sci 24:155-157
    • (2000) J Dermatol Sci , vol.24 , pp. 155-157
    • Stanley, J.R.1
  • 35
    • 0012023460 scopus 로고    scopus 로고
    • Evidence that pemphigus vulgaris IgG causes no steric hindrance in desmosome formation, but forms desmoglein 3-deficiebt desmosomes
    • Kitajima Y, Tsujimura Y, Sato M, Yamaguchi F, Aoyama Y (2001) Evidence that pemphigus vulgaris IgG causes no steric hindrance in desmosome formation, but forms desmoglein 3-deficiebt desmosomes. J Invest Dermatol 117:406 (abstract)
    • (2001) J Invest Dermatol , vol.117 , pp. 406
    • Kitajima, Y.1    Tsujimura, Y.2    Sato, M.3    Yamaguchi, F.4    Aoyama, Y.5
  • 36
    • 0033067371 scopus 로고    scopus 로고
    • A pathogenic autoantibody, pemphigus IgG, induces phosphorylation of desmoglein 3, and its dissociation from plakoglobin in cultured keratinocytes
    • Aoyama Y, Owada MK, Kitajima Y (1999) A pathogenic autoantibody, pemphigus IgG, induces phosphorylation of desmoglein 3, and its dissociation from plakoglobin in cultured keratinocytes. Eur J Immunol 29:2233-2240
    • (1999) Eur J Immunol , vol.29 , pp. 2233-2240
    • Aoyama, Y.1    Owada, M.K.2    Kitajima, Y.3
  • 37
    • 0032900965 scopus 로고    scopus 로고
    • Pemphigus vulgaris-IgG causes a rapid depletion of desmoglein 3(Dsg3) from the triton X-100 soluble pools, leading to the formation of Dsg3-depleted desmosomes in a human squamous carcinoma cell line, DJM-1 cells
    • Aoyama Y, Kitajima Y (1999) Pemphigus vulgaris-IgG causes a rapid depletion of desmoglein 3(Dsg3) from the triton X-100 soluble pools, leading to the formation of Dsg3-depleted desmosomes in a human squamous carcinoma cell line, DJM-1 cells. J Invest Dermatol 112:67-71
    • (1999) J Invest Dermatol , vol.112 , pp. 67-71
    • Aoyama, Y.1    Kitajima, Y.2
  • 38
    • 33751098790 scopus 로고    scopus 로고
    • Pathogenic monoclonal antibody against desmoglein 3 augments desmoglein 3 and p38 MAPK Phosphorylation in human squamous carcinoma cell line
    • Kawasaki Y, Aoyama Y, Tsunoda K, Amagai M, Kitajima Y (2006) Pathogenic monoclonal antibody against desmoglein 3 augments desmoglein 3 and p38 MAPK Phosphorylation in human squamous carcinoma cell line. Autoimmunity 39:587-590
    • (2006) Autoimmunity , vol.39 , pp. 587-590
    • Kawasaki, Y.1    Aoyama, Y.2    Tsunoda, K.3    Amagai, M.4    Kitajima, Y.5
  • 39
    • 21244476854 scopus 로고    scopus 로고
    • Desmosome signaling. Inhibition of p38MAPK prevents pemphigus vulgaris IgG-induced cytoskeleton reorganization
    • 23
    • Berkowitz P, Hu P, Liu Z, Diaz LA, Enghild JJ, Chua MP, Rubinstggein DS (2005) Desmosome signaling. Inhibition of p38MAPK prevents pemphigus vulgaris IgG-induced cytoskeleton reorganization. J Biol Chem 280(23):23778-23784
    • (2005) J Biol Chem , vol.280 , pp. 23778-23784
    • Berkowitz, P.1    Hu, P.2    Liu, Z.3    Diaz, L.A.4    Enghild, J.J.5    Chua, M.P.6    Rubinstggein, D.S.7
  • 40
    • 41949103086 scopus 로고    scopus 로고
    • The cytoplasmic membrane-proximal region of desmoglein 3 is critical for p120ctn binding to desmoglein 3
    • Aoyama Y, Kanno M, Nagai M, Yamamoto Y, Ozawa M, Kitajima Y (2006) The cytoplasmic membrane-proximal region of desmoglein 3 is critical for p120ctn binding to desmoglein 3. J Invest Dermatol 126:32 (abstract)
    • (2006) J Invest Dermatol , vol.126 , pp. 32
    • Aoyama, Y.1    Kanno, M.2    Nagai, M.3    Yamamoto, Y.4    Ozawa, M.5    Kitajima, Y.6
  • 41
    • 41949083547 scopus 로고    scopus 로고
    • Different anti-desmoglein 3 monoclonal antibodies exert epitope-specific regulation of p120 catenin phosphorylation and of p120 catenin binding to desmoglein 3 in human squamous cell carcinoma cell line, DJM-1 cells
    • Kawasaki Y, Aoyama Y, Tsunoda K, Amagai M, Kitajima Y (2006) Different anti-desmoglein 3 monoclonal antibodies exert epitope-specific regulation of p120 catenin phosphorylation and of p120 catenin binding to desmoglein 3 in human squamous cell carcinoma cell line, DJM-1 cells. J Invest Dermatol 126:6 (abstract)
    • (2006) J Invest Dermatol , vol.126 , pp. 6
    • Kawasaki, Y.1    Aoyama, Y.2    Tsunoda, K.3    Amagai, M.4    Kitajima, Y.5
  • 43
    • 0037238398 scopus 로고    scopus 로고
    • Fas ligand in pemphigus sera induces keratinocyte apoptosis through the activation of caspase-8
    • Puviani M, Marconi A, Cozzani E, Pincelli C (2003) Fas ligand in pemphigus sera induces keratinocyte apoptosis through the activation of caspase-8. J Invest Dermatol 120:164-167
    • (2003) J Invest Dermatol , vol.120 , pp. 164-167
    • Puviani, M.1    Marconi, A.2    Cozzani, E.3    Pincelli, C.4
  • 44
    • 2942532918 scopus 로고    scopus 로고
    • Replicative senescence enhances apoptosis induced by pemphigus autoimmune antibodies in human keratinocytes
    • Wang X, Brégégère F, Soroka Y, Frusic-Zlotkin M, Milner Y (2004) Replicative senescence enhances apoptosis induced by pemphigus autoimmune antibodies in human keratinocytes. FEBS Lett 567:281-286
    • (2004) FEBS Lett , vol.567 , pp. 281-286
    • Wang, X.1    Brégégère, F.2    Soroka, Y.3    Frusic-Zlotkin, M.4    Milner, Y.5
  • 45
    • 28244492845 scopus 로고    scopus 로고
    • Novel mechanisms of target cell death and survival and of therapeutic action of IVIg in pemphigus
    • Arredondo J, Chernyavsky AI, Karaouni A, Grando SA (2005) Novel mechanisms of target cell death and survival and of therapeutic action of IVIg in pemphigus. Am J Pathol 167:1531-1544
    • (2005) Am J Pathol , vol.167 , pp. 1531-1544
    • Arredondo, J.1    Chernyavsky, A.I.2    Karaouni, A.3    Grando, S.A.4
  • 47
    • 0020675063 scopus 로고
    • Anti-cell surface pemphigus antibody stimulates plasminogen activator activity of human epidermal cells. a mechanism for the loss of epidermal cohesion and blister formation
    • Hashimoto K, Shafran KM, Webber PA, Lazarus GS, Singer KH (1983) Anti-cell surface pemphigus antibody stimulates plasminogen activator activity of human epidermal cells. A mechanism for the loss of epidermal cohesion and blister formation. J Exp Med 157:259-272
    • (1983) J Exp Med , vol.157 , pp. 259-272
    • Hashimoto, K.1    Shafran, K.M.2    Webber, P.A.3    Lazarus, G.S.4    Singer, K.H.5
  • 48
    • 0029059657 scopus 로고
    • Pharmacologic evidence for involvement of phospholipase C in pemphigus IgG-induced inositol 1,4,5-trisphosphate generation, intracellular calcium increase, and plasminogen activator secretion in DJM-1 cells, a squamous cell carcinoma line
    • Esaki C, Seishima M, Yamada T, Osada K, Kitajima Y (1995) Pharmacologic evidence for involvement of phospholipase C in pemphigus IgG-induced inositol 1,4,5-trisphosphate generation, intracellular calcium increase, and plasminogen activator secretion in DJM-1 cells, a squamous cell carcinoma line. J Invest Dermatol 105:329-333
    • (1995) J Invest Dermatol , vol.105 , pp. 329-333
    • Esaki, C.1    Seishima, M.2    Yamada, T.3    Osada, K.4    Kitajima, Y.5
  • 49
    • 0024590119 scopus 로고
    • Characterization of keratinocyte plasminogen activator inhibitors and demonstration of the prevention of pemphigus IgG-induced acantholysis by a purified plasminogen activator inhibitor
    • Hashimoto K, Wun T-C, Baird J, Lazarus GS, Jensen PJ (1989) Characterization of keratinocyte plasminogen activator inhibitors and demonstration of the prevention of pemphigus IgG-induced acantholysis by a purified plasminogen activator inhibitor. J Invest Dermatol 92:310-315
    • (1989) J Invest Dermatol , vol.92 , pp. 310-315
    • Hashimoto, K.1    Wun, T.-C.2    Baird, J.3    Lazarus, G.S.4    Jensen, P.J.5
  • 50
    • 0032809239 scopus 로고    scopus 로고
    • Pemphigus vulgaris and pemphigus foliaceus antibodies are pathogenic in plasminogen activator knockout mice
    • Mahoney MG, Wang ZH, Stanley JR (1999) Pemphigus vulgaris and pemphigus foliaceus antibodies are pathogenic in plasminogen activator knockout mice. J Invest Dermatol 113:22-25
    • (1999) J Invest Dermatol , vol.113 , pp. 22-25
    • Mahoney, M.G.1    Wang, Z.H.2    Stanley, J.R.3
  • 51
    • 0033792693 scopus 로고    scopus 로고
    • Assembly pathway pf desmoglein 3 to desmosomes and its perturbation by pemphigus vulgaris-IgG in cultured keratinocytes, as revealed by time-lapsed labeling immunoelectron microscopy
    • Sato M, Aoyama Y, Kitajima Y (2000) Assembly pathway pf desmoglein 3 to desmosomes and its perturbation by pemphigus vulgaris-IgG in cultured keratinocytes, as revealed by time-lapsed labeling immunoelectron microscopy. Lab Invest 80:1583-1592
    • (2000) Lab Invest , vol.80 , pp. 1583-1592
    • Sato, M.1    Aoyama, Y.2    Kitajima, Y.3
  • 52
    • 28444470500 scopus 로고    scopus 로고
    • Pemphigus vulgaris-IgG reduces the desmoglein 3/desmocollin 3 ratio on the cell surface in cultured keratinocytes as revealed by double-staining immunoelectron microscopy
    • Shu E, Yamamoto Y, Sato-Nagai M, Aoyama Y, Kitajima Y (2005) Pemphigus vulgaris-IgG reduces the desmoglein 3/desmocollin 3 ratio on the cell surface in cultured keratinocytes as revealed by double-staining immunoelectron microscopy. J Dermatol Sci 40:209-211
    • (2005) J Dermatol Sci , vol.40 , pp. 209-211
    • Shu, E.1    Yamamoto, Y.2    Sato-Nagai, M.3    Aoyama, Y.4    Kitajima, Y.5
  • 54
    • 33646592529 scopus 로고    scopus 로고
    • Serum from pemphigus vulgaris reduces desmoglein 3 half-life and perturbs its de novo assembly to desmosomal sites in cultured keratinocytes
    • Cirillo N, Femiano F, Gombos F, Lanza A (2006) Serum from pemphigus vulgaris reduces desmoglein 3 half-life and perturbs its de novo assembly to desmosomal sites in cultured keratinocytes. FEBS Lett 580:3276-3281
    • (2006) FEBS Lett , vol.580 , pp. 3276-3281
    • Cirillo, N.1    Femiano, F.2    Gombos, F.3    Lanza, A.4
  • 55
    • 34547113086 scopus 로고    scopus 로고
    • Anti-desmoglein 3 (Dsg3) monoclonal antibodies deplete desmosomes of Dsg3 and differ in their Dsg3-depleting activities related to pathogenicity
    • Yamamoto Y, Aoyama Y, Shu E, Tsunoda K, Amagai K, Kitajima Y (2007) Anti-desmoglein 3 (Dsg3) monoclonal antibodies deplete desmosomes of Dsg3 and differ in their Dsg3-depleting activities related to pathogenicity. J Biol Chem 282:17866-17876
    • (2007) J Biol Chem , vol.282 , pp. 17866-17876
    • Yamamoto, Y.1    Aoyama, Y.2    Shu, E.3    Tsunoda, K.4    Amagai, K.5    Kitajima, Y.6
  • 56
    • 34249724373 scopus 로고    scopus 로고
    • Intraperitoneal injection of pemphigus vulgaris-IgG into mouse depletes epidermal keratinocytes of desmoglein 3 associated with generation of acantholysis
    • Shu E, Yamamoto Y, Aoyama Y, Kitajima Y (2007) Intraperitoneal injection of pemphigus vulgaris-IgG into mouse depletes epidermal keratinocytes of desmoglein 3 associated with generation of acantholysis. Arch Dermatol Res 299:165-167
    • (2007) Arch Dermatol Res , vol.299 , pp. 165-167
    • Shu, E.1    Yamamoto, Y.2    Aoyama, Y.3    Kitajima, Y.4    Amagai, K.5    Kitajima, Y.6
  • 57
    • 0033978552 scopus 로고    scopus 로고
    • Induction of keratinocyte interleukin-8 expression and secretion by IgG autoantibodies as a novel mechanism of epidermal neutrophil recruitment in a pemphigus variant
    • O'Toole EA, Mak LL, Guitart J, Woodley DT, Hashimoto T, Amagai M, Chan LS (2000) Induction of keratinocyte interleukin-8 expression and secretion by IgG autoantibodies as a novel mechanism of epidermal neutrophil recruitment in a pemphigus variant. Clin Exp Immunol 119:217-224
    • (2000) Clin Exp Immunol , vol.119 , pp. 217-224
    • O'Toole, E.A.1    Mak, L.L.2    Guitart, J.3    Woodley, D.T.4    Hashimoto, T.5    Amagai, M.6    Chan, L.S.7
  • 58
    • 0034120496 scopus 로고    scopus 로고
    • Detection of antigen-specific B cells in patients with pemphigus vulgaris by enzyme-linked immunospot assay: Requirement of T cell collaboration for autoantibody production
    • Nishifuji K, Anagai M, Kuwana T, Iwassaki T, Nishikawa T (2000) Detection of antigen-specific B cells in patients with pemphigus vulgaris by enzyme-linked immunospot assay: requirement of T cell collaboration for autoantibody production. J Invest Dermatol 114:88-94
    • (2000) J Invest Dermatol , vol.114 , pp. 88-94
    • Nishifuji, K.1    Anagai, M.2    Kuwana, T.3    Iwassaki, T.4    Nishikawa, T.5
  • 59
    • 0037218618 scopus 로고    scopus 로고
    • Dichotomy of autoreactive Th1 and Th2 cell responses to desmoglein 3 in patients with pemphigus vulgaris (PV) and healthy carriers of PV-associated HLA class II alleles
    • Veldman CA, Stauber R, Wasssmuth W, Ulter W, Schuler G, Hertl M (2003) Dichotomy of autoreactive Th1 and Th2 cell responses to desmoglein 3 in patients with pemphigus vulgaris (PV) and healthy carriers of PV-associated HLA class II alleles. J Immunol 170:635-642
    • (2003) J Immunol , vol.170 , pp. 635-642
    • Veldman, C.A.1    Stauber, R.2    Wasssmuth, W.3    Ulter, W.4    Schuler, G.5    Hertl, M.6
  • 60
    • 1542619242 scopus 로고    scopus 로고
    • T cell recognition of desmoglein 3 peptides in patients with pemphigus vulgaris and healthy individuals
    • Veldman CA, Gebhard K, Ulter W, Wasssmuth W, Goetzinger J, Hertl (2003) T cell recognition of desmoglein 3 peptides in patients with pemphigus vulgaris and healthy individuals. J Immunol 172:3883-3892
    • (2003) J Immunol , vol.172 , pp. 3883-3892
    • Veldman, C.A.1    Gebhard, K.2    Ulter, W.3    Wasssmuth, W.4    Goetzinger, J.5    Hertl6
  • 61
    • 2442535915 scopus 로고    scopus 로고
    • Type I regulatory T cells specific for desmoglein 3 are more frequently detected in healthy individuals than in patients with pemphigus vulgaris
    • Veldman CA, Hohne D, Dieckman G, Schuler G, Hertl (2004) Type I regulatory T cells specific for desmoglein 3 are more frequently detected in healthy individuals than in patients with pemphigus vulgaris. J Immunol 172:6468-6475
    • (2004) J Immunol , vol.172 , pp. 6468-6475
    • Veldman, C.A.1    Hohne, D.2    Dieckman, G.3    Schuler, G.4    Hertl5
  • 62
    • 33644550620 scopus 로고    scopus 로고
    • Inhibition of the transcription factor Foxp3 converts desmoglein 3-specific type 1 regulatory T cells into Th2-like cells
    • Veldman C, Pahl A, Beissert S, Hansen W, Buer J, Dieckmann D, Schuler G, Hertl M (2006) Inhibition of the transcription factor Foxp3 converts desmoglein 3-specific type 1 regulatory T cells into Th2-like cells. J Immunol 176:3215-3222
    • (2006) J Immunol , vol.176 , pp. 3215-3222
    • Veldman, C.1    Pahl, A.2    Beissert, S.3    Hansen, W.4    Buer, J.5    Dieckmann, D.6    Schuler, G.7    Hertl, M.8
  • 63
    • 33646411527 scopus 로고    scopus 로고
    • T cell control in autoimmune bullous skin disorders
    • Hertl M, Eming R, Veldman C (2006) T cell control in autoimmune bullous skin disorders. J Clin Invest 116:1159-1166 (review)
    • (2006) J Clin Invest , vol.116 , pp. 1159-1166
    • Hertl, M.1    Eming, R.2    Veldman, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.