Long-term treatment with a Yang-invigorating Chinese herbal formula produces generalized tissue protection against oxidative damage in rats

Rejuvenation Research

Volumn 11, Issue 1, 2008, Pages 43-62

  Chiu, Po Yee ^a   Leung, Hoi Yan ^a   Ling Siu, Ada Hoi ^a   Chen, Na ^a   Poon, Michel K T ^a   Ko, Kam Ming ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON TETRACHLORIDE; CHINESE DRUG; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOCHROME C; HEMOGLOBIN; HERBACEOUS AGENT; UNCLASSIFIED DRUG; VIGCONIC 28;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN INJURY; CALCIUM TRANSPORT; CELL DAMAGE; CELL FUNCTION; CHINESE MEDICINE; CONTROLLED STUDY; ERYTHROCYTE; FEMALE; HERBAL MEDICINE; LIVER TOXICITY; LONG TERM CARE; MITOCHONDRION; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; TREATMENT DURATION;

ANIMALS; CARBON TETRACHLORIDE; CARNOSINE; CHOLECALCIFEROL; CYTOPROTECTION; DNA DAMAGE; DRUGS, CHINESE HERBAL; FEMALE; GENTAMICINS; HYPOXIA-ISCHEMIA, BRAIN; KIDNEY DISEASES; LIVER DISEASES; MALE; MYOCARDIAL REPERFUSION INJURY; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SUPEROXIDE DISMUTASE; TIME FACTORS; YANG DEFICIENCY;

RATTUS;

EID: 39449136770     PISSN: 15491684     EISSN: None     Source Type: Journal    
DOI: 10.1089/rej.2007.0577     Document Type: Article

References (60)

1. Brookes PS, Levonen AL, Shiva S, Sarti P, Darley-Usmar VM. Mitochondria: regulators of signal transduction by reactive oxygen and nitrogen species. Free Radic Biol Med 2002;33:755-764.
2. McFalls EO, Liem D, Schoonderwoerd K, Lamers J, Sluiter W, Duncker D. Mitochondrial function: the heart of myocardial preservation. J Lab Clin Med 2003;142:141-148.
3. Petersen A, Castilho RF, Hansson O, Wieloch T, Brundin P. Oxidative stress, mitochondrial permeability transition and activation of caspases in calcium ionophore A23187-induced death of cultured striatal neurons. Brain Res 2000;857:20-29.
4. Adachi M, Ishii H. Role of mitochondria in alcoholic liver injury. Free Radic Biol Med 2002;32:487-491.
5. Genova ML, Pich MM, Bernacchia A, Bianchi C, Biondi A, Bovina C, Falasca AI, Formiggini G, Castelli GP, Lenaz G. The mitochondrial production of reactive oxygen species in relation to aging and pathology. Ann NY Acad Sci 2004;1011:86-100.
6. Oliveira PJ. Cardiac mitochondrial alterations observed in hyperglycemic rats. What can we learn from cell biology? Curr Diabetes Rev 2005;1:11-21.
7. Moro MA, Almeida A, Bolanos JP, Lizasoain I. Mitochondrial respiratory chain and free radical generation in stroke. Free Radic Biol Med 2005;39:1291-1304.
8. Kowaltowski AJ, Castilho RF, Vercesi AE. Mitochondrial permeability transition and oxidative stress. FEBS Lett 2001;495:12-15.
9. 2+-induced reactive oxygen species production promotes cytochrome c release from rat liver mitochondria via mitochondrial permeability transition (MPT)-dependent and MPT-independent mechanisms: role of cardiolipin. J Biol Chem 2004;279:53103-53108.
10. Leung HY, Chiu PY, Poon MK, Ko KM. A Yang-invigorating Chinese herbal formula enhances mitochondrial functional ability and antioxidant capacity in various tissues of male and female rats. Rejuven Res 2005;8:238-247.
11. Mak DH, Chiu PY, Poon MK, Ng TT, Chung YK, Lam BY, Du Y, Ko KM. A yang-promoting Chinese herbal suppository preparation enhances the antioxidant status of red cells in male human subjects. Phytother Res 2004;18:525-530.
12. CDER. Estimating the maximum safe starting dose in initial clinical trials for therapeutics in adult healthy volunteers. FDA. Guidance for Industry, Pharmacology and Toxicology, Washinton, DC, 2005.
13. Ichikawa H, Konishi T. In vitro antioxidant potentials of traditional Chinese medicine, Shengmai San and their relation to in vivo protective effect on cerebral oxidative damage in rats. Biol Pharm Bull 2002;25:898-903.
14. Li PC, Mak DHF, Poon MKT, Ip SP, Ko KM. Myocardial protective effect of Sheng Mai San (SMS) and a lignan-enriched extract of Fructus Schisandrae, in vivo and ex vivo. Phytomedicine 1996;3:217-221.
15. Evans WH. Isolation and characterization of membranes and organelles. In: Rickwood D, ed: Preparative Centrifugation: A Practical Approach. Oxford University Press, New York, 1992, pp.233-270.
16. Chiu PY, Leung HY, Poon MK, Ko KM. Chronic schisandrin B treatment improves mitochondrial antioxidant status and tissue heat shock protein production in various tissues of young adult and middleaged rats. Biogerontology 2006;7:199-210.
17. Griffith OW. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal Biochem 1980;106:207-212.
18. Sadrzadeh SM, Nanji AA, Meydani M. Effect of chronic ethanol feeding on plasma and liver alphaand gamma-tocopherol levels in normal and vitamin E-deficient rats. Relationship to lipid peroxidation. Biochem Pharmacol 1994;47:2005-2010.
19. McCord JM, Fridovich I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem 1969;244:6049-6055.
20. Chiu PY, Mak DH, Poon MK, Ko KM. In vivo antioxidant action of a lignan-enriched extract of Schisandra fruit and an anthraquinone-containing extract of Polygonum root in comparison with schisandrin B and emodin. Planta Med 2002;68:951-956.
21. Drabkin DL, Austin JH. Spectrophotometric studies. V. A technique for the analysis of undiluted blood and concentrated hemoglobin solutions. J Biol Chem 1935;112:51-65.
22. Demin OV, Kholodenko BN, Skulachev VP. A model of O2-generation in the complex III of the electron transport chain. Mol Cell Biochem 1998;184:21-33.
23. Ambrosio G, Zweier JL, Duilio C, Kuppusamy P, Santoro G, Elia PP, Tritto I, Cirillo P, Condorelli M, Chiariello M . Evidence that mitochondrial respiration is a source of potentially toxic oxygen free radicals in intact rabbit hearts subjected to ischemia and reflow. J Biol Chem 1993;268:18532- 18541.
24. Chan PH. Mitochondrial dysfunction and oxidative stress as determinants of cell death/survival in stroke. Ann NY Acad Sci 2005;1042:203-209.
25. Castello PR Drechsel DA, Patel M. Mitochondria are a major source of paraquat-induced reactive oxygen species production in the brain. J Biol Chem 2007;282:14186(14193.
26. Stavrovskaya IG, Kristal BS. The powerhouse takes control of the cell: is the mitochondrial permeability transition a viable therapeutic target against neuronal dysfunction and death? Free Radic Biol Med 2005;38:687-697.
27. Weissig V, Cheng SM, D'Souza GG. Mitochondrial pharmaceutics. Mitochondrion 2004;3:229-244.
28. Linford NJ, Schriner SE, Rabinovitch PS. Oxidative damage and aging: spotlight on mitochondria. Cancer Res 2006;66:2497-2499.
29. Yim TK, Ko KM. Schisandrin B protects against myocardial ischemia-reperfusion injury by enhancing myocardial glutathione antioxidant status. Mol Cell Biochem 1999;196:151-156.
30. Chiu PY, Tang MH, Mak DH, Poon MK, Ko KM. Hepatoprotective mechanism of schisandrin B: role of mitochondrial glutathione antioxidant status and heat shock proteins. Free Radic Biol Med 2003;35:368-380.
31. Ali BH. Agents ameliorating or augmenting experimental gentamicin nephrotoxicity: some recent research. Food Chem Toxicol 2003;41:1447-1452.
32. Callio J, Oury TD, Chu CT. Manganese superoxide dismutase protects against 6-hydroxydopamine injury in mouse brains. J Biol Chem 2005;280:18536-18542.
33. Navarro A, Gomez C, Sanchez-Pino MJ, Gonzalez H, Bandez MJ, Boveris AD, Boveris A. Vitamin E at high doses improves survival, neurological performance, and brain mitochondrial function in aging male mice. Am J Physiol Regul Integr Comp Physiol 2005;289:R1392-R1399.
34. Chen Z, Siu B, Ho YS, Vincent R, Chua CC, Hamdy RC, Chua BH. Overexpression of MnSOD protects against myocardial ischemia/reperfusion injury in transgenic mice. J Mol Cell Cardiol 1998;30:2281-2289.
35. Shen X, Zheng S, Metreveli NS, Epstein PN. Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy. Diabetes 2006;55:798-805.
36. Wheeler MD, Nakagami M, Bradford BU, Uesugi T, Mason RP, Connor HD, Dikalova A, Kadiiska M, Thurman RG. Overexpression of manganese superoxide dismutase prevents alcohol-induced liver injury in the rat. J Biol Chem 2001;276:36664-36672.
37. Dhanarajan R, Abraham P, Isaac B. Protective effect of ebselen, a selenoorganic drug, against gentamicin-induced renal damage in rats. Basic Clin Pharmacol Toxicol 2006;99:267-272.
38. Soliman KM, Abdul-Hamid M, Othman AI. Effect of carnosine on gentamicin-induced nephrotoxicity. Med Sci Monit 2007;13:BR73-BR83.
39. 2+ signaling. Am J Physiol Cell Physiol 2006;291:C1082-C1088.
40. Kim JA, Formoso G, Li Y, Potenza MA, Marasciulo FL, Montagnani M, Quon MJ. Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and Fyn. J Biol Chem 2007;282:13736-13745.
41. Feng R, Ni HM, Wang SY, Tourkova IL, Shurin MR, Harada H, Yin XM. Cyanidin-3-rutinoside, a natural polyphenol antioxidant, selectively kills leukemic cells by induction of oxidative stress. J Biol Chem 2007;282:13468-13476.
42. Nelson SK, Bose SK, Grunwald GK, Myhill P, McCord JM. The induction of human superoxide dismutase and catalase in vivo: a fundamentally new approach to antioxidant therapy. Free Radic Biol Med 2006;40:341-347.
43. Lemasters JJ, Nieminen AL, Qian T, Trost LC, Elmore SP, Nishimura Y, Crowe RA, Cascio WE, Bradham CA, Brenner DA, Herman B. The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy. Biochim Biophys Acta 1998;1366:177-196.
44. Tsujimoto Y, Shimizu S. Role of the mitochondrial membrane permeability transition in cell death. Apoptosis 2007;12:835-840.
45. Galat A, Metcalfe SM. Peptidylproline cis/trans isomerases. Prog Biophys Mol Biol 1995;63:67-118.
46. Redegeld FA, Moison RM, Koster AS, Noordhoek J. Depletion of ATP but not of GSH affects viability of rat hepatocytes. Eur J Pharmacol 1992;228:229-236.
47. Green DR, Reed JC. Mitochondria and apoptosis. Science 1998;281:1309-1312.
48. Kang PM, Haunstetter A, Aoki H, Usheva A, Izumo S. Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation. Circ Res 2000;87:118-125.
49. Brookes PS, Yoon Y, Robotham JL, Anders MW, Sheu SS. Calcium, ATP, and ROS: a mitochondrial lovehate triangle. Am J Physiol Cell Physiol 2004;287:C817-C833.
50. Meister A, Anderson ME. Glutathione. Annu Rev Biochem 1983;52:711-760.
51. Reed DJ. Glutathione: toxicological implications. Annu Rev Pharmacol Toxicol 1990;30:603-631.
52. Costantini P, Petronilli V, Colonna R, Bernardi P. On the effects of paraquat on isolated mitochondria. Evidence that paraquat causes opening of the cyclosporin A-sensitive permeability transition pore synergistically with nitric oxide. Toxicology 1995;99:77-88.
53. Reed DJ, Savage MK. Influence of metabolic inhibitors on mitochondrial permeability transition and glutathione status. Biochim Biophys Acta 1995;1271:43-50.
54. Halestrap AP, Connern CP, Griffiths EJ, Kerr PM. Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury. Mol Cell Biochem 1997;174:167-172.
55. Chiang CS, Liu WC, Jung SM, Chen FH, Wu CR, McBride WH, Lee CC, Hong JH. Compartmental responses after thoracic irradiation of mice: strain differences. Int J Radiat Oncol Biol Phys 2005;62:862-871.
56. Ahmed FN, Naqvi FN, Shafiq F. Lipid peroxidation and serum antioxidant enzymes in patients with type 2 diabetes mellitus. Ann NY Acad Sci 2006;1084:481-489.
57. Nikolic-Kokic A, Stevic Z, Blagojevic D, Davidovic B, Jones DR, Spasic MB. Alterations in anti-oxidative defence enzymes in erythrocytes from sporadic amyotrophic lateral sclerosis (SALS) and familial ALS patients. Clin Chem Lab Med 2006;44:589-593.
58. Zawadzka-Bartczak E. Activities of red blood cell anti-oxidative enzymes (SOD, GPx) and total anti-oxidative capacity of serum (TAS) in men with coronary atherosclerosis and in healthy pilots. Med Sci Monit 2005;11:CR440-CR444.
59. Park EM, Ramnath N, Yang GY, Ahn JY, Park Y, Lee TY, Shin HS, Yu J, Ip C, Park YM. High superoxide dismutase and low glutathione peroxidase activities in red blood cells predict susceptibility of lung cancer patients to radiation pneumonitis. Free Radic Biol Med 2007;42:280-287.
60. Chui SH, Ko KM. Biochemical, immunological, hormonal and anti-oxidant effects of a Chinese herbal suppository, Vigconic HY28, in elderly male subjects - an anti-aging solutions? Presented at the Anti-Aging World Conference, Paris, November 2003.