Na+ Channel Reorganization in Demyelinated Axons

Multiple Sclerosis As A Neuronal Disease

Volumn , Issue , 2005, Pages 119-130

  Shrager, Peter ^a   Simon, William ^a   Kazarinova Noyes, Katia ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 39349110162     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012738761-1/50009-2     Document Type: Chapter

References (69)

1. E.J. Arroyo, R. Chitale and S.S. Scherer (2003) Paranodal demyelination disrupts the molecular organization of nodes. Soc. Neurosci. Abs. 675.5
2. V. Bennett and S. Lambert (1999) Physiological roles of axonal ankyrins in survival of premyelinated axons and localization of voltage-gated sodium channels. J. Neurocytol. 28 303-318.
3. S. Berghs, D. Aggujaro, R. Dirkx Jr., E. Maksimova, P. Stabach, J.M. Hermel, J.P. Zhang, W. Philbrick, V. Slepnev, T. Ort and M. Solimena (2000) BetaIV spectrin, a new spectrin localized at axon initial segments and nodes of Ranvier in the central and peripheral nervous system. J Cell Biol. 151 985-1002.
4. T. Boiko, M.N. Rasband, S.R. Levinson, J.H. Caldwell, G. Mandel, J.S. Trimmer and G. Matthews (2001) Compact myelin dictates the differential targeting of two sodium channel isoforms in the same axon. Neuron 30 91-104.
5. T. Boiko, A. Van Wart, J.H. Caldwell, S.R. Levinson, J.S. Trimmer and G. Matthews (2003) Functional specialization of the axon initial segment by isoform-specific sodium channel targeting. J. Neurosci. 23 2306-2313.
6. H. Bostock and T.A. Sears (1978) The internodal axon membrane: electrical excitability and continuous conduction in segmental demyelination. J. Physiol. 280 273-301.
7. J.H. Caldwell, K.L. Schaller, R.S. Lasher, E. Peles and S.R. Levinson (2000) Sodium channel Na(v) 1.6 is localized at nodes of Ranvier, dendrites, and synapses. Proc. Natl. Acad. Sci. U.S.A. 97 5616-5620.
8. W. Ching, G. Zanazzi, S.R. Levinson and J.L. Salzer (1999) Clustering of neuronal sodium channels requires contact with myelinating Schwann cells. J. Neurocytol. 28 295-301.
9. S.Y. Chiu (1993) Differential expression of sodium channels in acutely isolated myelinating and non-myelinating Schwann cells of rabbits. J. Physiol. 470 485-499.
10. S.Y. Chiu, J.M. Ritchie, R.B. Rogart and D. Stagg (1979) A quantitative description of membrane currents in rabbit myelinated nerve. J. Physiol. 292 149-166.
11. S.Y. Chiu and W. Schwarz (1987) Sodium and potassium currents in acutely demyelinated internodes of rabbit sciatic nerves. J. Physiol. 391 631-649.
12. S.Y. Chiu, P. Shrager and J.M. Ritchie (1984) Neuronal-type Na+ and K+ channels in rabbit cultured Schwann cells. Nature 311 156-157.
13. M.J. Craner, B.C. Hains, A.C. Lo, J.A. Black and S.G. Waxman (2004) Co-localization of sodium channel Nav1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE. Brain 127 294-303.
14. J. Crank (1975) The Mathematics of Diffusion London: Oxford University Press
15. A.W. Custer, K. Kazarinova-Noyes, T. Sakurai, X. Xu, W. Simon, M. Grumet and P. Shrager (2003) The role of the ankyrin-binding protein NrCAM in node of Ranvier formation. J. Neurosci. 23 10032-10039.
16. F. Dodge and B. Frankenhauser (1959) Sodium currents in the myelinated nerye fibre of Xenopus laevis investigated with the voltage clamp technique. J. Physiol. 148 188-200.
17. S. Dugandzija-Novakovic, A.G. Koszowski, S.R. Levinson and P. Shrager (1995) Clustering of Na channels and node of Ranvier formation in remyelinating axons. J. Neurosci. 15 492-502.
18. M.H. Ellisman and S.R. Levinson (1982) Immunocytochemical localization of sodium channel distributions in the excitable membranes of Electrophorus electricus. Proc. Natl. Acad. Sci. U.S.A. 79 6707-6711.
19. P.A. Felts, T.A. Baker and K.J. Smith (1997) Conduction in segmentally demyelinated mammalian central axons. J. Neurosci. 17 7267-7277.
20. T.D. Garver, Q. Ren, S. Tuvia and V. Bennett (1997) Tyrosine phosphorylation at a site highly conserved in the L1 family of cell adhesion molecules abolishes ankyrin binding and increases lateral mobility of neurofascin. J. Cell Biol. 137 703-714.
21. S. Grissmer (1986) Properties of potassium and sodium channels in frog internode. J. Physiol. 381 119-134.
22. S.M. Hall and N.A. Gregson (1971) The in vivo and ultrastructural effects of injection of lysophosphatidyl choline into myelinated peripheral nerve fibres of the adult mouse. J. Cell Sci. 9 769-789.
23. B. Hille (2001) Ionic Channels of Excitable Membranes Sunderland, MA: Sinauer Associates
24. A.F. Huxley and R. Stampfli (1949) Evidence for saltatory conduction in peripheral myelinated nerve fibres. J. Physiol. 108 315-339.
25. Y. Inoue, R. Nakamura, M. Mikoshiba and Y. Tsukada (1981) Fine structure of the central myelin sheath in the myelin deficient mutant Shivere mouse, with special reference to the pattern of myelin formation by oligodendroglia. Brain Res. 219 85-94.
26. S.M. Jenkins, K. Kizhatil, N.R. Kramarcy, A. Sen, R. Sealock and V. Bennett (2001) FIGQY phosphorylation defines discrete populations of L1 cell adhesion molecules at sites of cell-cell contact and in migrating neurons. J Cell Sci. 114 3823-3835.
27. M.R. Kaplan, M.H. Cho, E.M. Ullian, L.L. Isom, S.R. Levinson and B.A. Barres (2001) Differential control of clustering of the sodium channels Na(v) 1.2 and Na(v) 1.6 at developing CNS nodes of Ranvier. Neuron 30 105-119.
28. M.R. Kaplan, A. Meyer-Franke, S. Lambert, V. Bennett, I.D. Duncan, S.R. Levinson and B.A. Barres (1997) Induction of sodium channel clustering by oligodendrocytes. Nature 386 724-728.
29. K. Kazarinova-Noyes and P. Shrager (2002) Molecular constituents of the node of Ranvier. Mol. Neurobiol. 26 167-182.
30. M. Komada and P. Soriano (2002) BetaIV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier. J. Cell Biol. 156 337-348.
31. E. Kordeli, S. Lambert and V. Bennett (1995) AnkyrinG. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier. J. Biol. Chem. 270 2352-2359.
32. S. Lambert, J.Q. Davis and V. Bennett (1997) Morphogenesis of the node of Ranvier: co-clusters of ankyrin and ankyrin-binding integral proteins define early developmental intermediates. J. Neurosci. 17 7025-7036.
33. J.D. Malhotra, M.C. Koopmann, K.A. Kazen-Gillespie, N. Fettman, M. Hortsch and L.L. Isom (2002) Structural requirements for interaction of sodium channel beta 1 subunits with ankyrin. J. Biol. Chem. 277 26681-26688.
34. R. Martini and M. Schachner (1986) Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve. J. Cell Biol. 103 2439-2448.
35. C.V. Melendez-Vasquez, J.C. Rios, G. Zanazzi, S. Lambert, A. Bretscher and J.L. Salzer (2001) Nodes of Ranvier form in association with ezrin-radixin-moesin (ERM)-positive Schwann cell processes. Proc. Natl. Acad. Sci. U.S.A. 98 1235-1240.
36. R.A. Mooney and D.L. Anderson (1989) Phosphorylation of the insulin receptor in permeabilized adipocytes is coupled to a rapid dephosphorylation reaction. J. Biol. Chem. 264 6850-6857.
37. R.A. Mooney and K.L. Bordwell (1992) Differential dephosphorylation of the insulin receptor and its 160-kDa substrate (pp160) in rat adipocytes. J. Biol. Chem. 267 14054-14060.
38. J.L. Noebels, P.K. Marcom and M.H. Jalilian-Tehrani (1991) Sodium channel density in hypomyelinated brain increased by myelin basic protein gene deletion. Nature 352 431-434.
39. S.D. Novakovic, T.J. Deerinck, S.R. Levinson, P. Shrager and M.H. Ellisman (1996) Clusters of axonal Na+ channels adjacent to remyelinating Schwann cells. J. Neurocytol. 25 403-412.
40. S.D. Novakovic, S.R. Levinson, M. Schachner and P. Shrager (1998) Disruption and reorganization of sodium channels in experimental allergic neuritis. Muscle Nerve 21 1019-1032.
41. S. Poliak and E. Peles (2003) The local differentiation of myelinated axons at nodes of Ranvier. Nat. Rev. Neurosci. 4 968-980.
42. D.C. Quick and S.G. Waxman (1977) Specific staining of the axon membrane at nodes of Ranvier with ferric ion and ferrocyanide. J. Neurol. Sci. 31 1-11.
43. I.M. Raman and B.P. Bean (1997) Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons. J. Neurosci. 17 4517-4526.
44. M.N. Rasband, E. Peles, J.S. Trimmer, S.R. Levinson, S.E. Lux and P. Shrager (1999) Dependence of nodal sodium channel clustering on paranodal axoglial contact in the developing CNS. J. Neurosci. 19 7516-7528.
45. M.N. Rasband, J.S. Trimmer, T.L. Schwarz, S.R. Levinson, M.H. Ellisman, M. Schachner and P. Shrager (1998) Potassium channel distribution, clustering, and function in remyelinating rat axons. J. Neurosci. 18 36-47.
46. C.F. Rasminsky and T.A. Sears (1972) Internodal conduction in undissected demyelinated nerve fibres. J. Physiol. 227 323-350.
47. C.F. Ratcliffe, Y. Qu, K.A. McCormick, V.C. Tibbs, J.E. Dixon, T. Scheuer and W.A. Catterall (2000) A sodium channel signaling complex: modulation by associated receptor protein tyrosine phosphatase beta. Nature Neurosci. 3 437-444.
48. J. Rosenbluth (1976) Intramembranous particle distribution at the node of Ranvier and adjacent axolemma in myelinated axons of the frog brain. J. Neurocytol. 5 731-745.
49. J. Rosenbluth (1980) Central myelin in the mouse mutant Shiverer. J. Comp. Neurol. 194 639-648.
50. J. Rosenbluth (1981) Freeze-fracture approaches to ionophore localization in normal and myelin-deficient nerves. Adv. Neurol. 31 391-418.
51. J.L. Salzer (2003) Polarized domains of myelinated axons. Neuron 40 297-318.
52. S.S. Scherer, T. Xu, P. Crino, E.J. Arroyo and D.H. Gutmann (2001) Ezrin, radixin, and moesin are components of Schwann cell microvilli. J. Neurosci. Res. 65 150-164.
53. P. Shrager (1987) The distribution of sodium and potassium channels in single demyelinated axons of the frog. J. Physiol. 392 587-602.
54. P. Shrager (1988) Nonic channels and signal conduction in single remyelinating frog nerve fibres. J. Physiol. 404 695-712.
55. P. Shrager (1989) Sodium channels in single demyelinated mammalian axons. Brain Res. 483 149-154.
56. P. Shrager, S.Y. Chiu and J.M. Ritchie (1985) Voltage-dependent sodium and potassium channels in mammalian cultured Schwann cells. Proc. Natl. Acad. Sci. U.S.A. 82 948-952.
57. P. Shrager and C.T. Rubinstein (1990) Optical measurement of conduction in single demyelinated axons. J. Gen. Physiol. 95 867-889.
58. W. Simon (1986) Mathematical Techniques for Biology and Medicine New York: Dover Publication, Inc.
59. K.J. Smith, H. Bostock and S.M. Hall (1982) Saltatory conduction precedes remyelination in axons demyelinated with lysophosphatidyl choline. J. Neurol. Sci. 54 13-31.
60. W. Struhmer and W. Almers (1982) Photobleaching through glass micropipettes: sodium channels without lateral mobility in the sarcolemma of frog skeletal muscle. Proc. Natl. Acad. Sci. U.S.A. 79 946-950.
61. I. Tasaki and T. Takeuchi (1942) Weitere Studien uber den Aktionsstrom der markhaltigen Nervensfasern und uber die elektrosaltatorische Ubertragung des Nervenimpulses. Pfluger Arch. 245 764-782.
62. B.D. Trapp, J. Peterson, R.M. Ransohoff, R. Rudick, S. Mork and L. Bo (1998) Axonal transection in the lesions of multiple sclerosis. N. Engl. J. Med. 338 278-285.
63. E. Tzomaka, S.D. Novakovic, S.R. Levinson and P. Shrager (1995) Na+ channel aggregation in remyelinating mouse sciatic axons following transection. Glia 15 188-194.
64. E. Tzoumaka, A.C. Tischler, L. Sangameswaran, R.M. Eglen, J.C. Hunter and S.D. Novakovic (2000) Differential distribution of the tetrodotoxin-sensitive rPN4/NaCh6/Scn8a sodium channel in the nervous system. J. Neurosci. Res. 60 37-44.
65. I. Vabnick, S.D. Novakovic, S.R. Levinson, M. Schachner and P. Shrager (1996) The clustering of axonal sodium channels during development of the peripheral nervous system. J. Neurosci. 16 4914-4922.
66. I. Vabnick, J.S. Trimmer, T.L. Schwarz, S.R. Levinson, D. Risal and P. Shrager (1999) Dynamic potassium channel distributions during axonal development prevent aberrant firing patterns. J. Neurosci. 19 747-758.
67. R.E. Westenbroek, J.L. Noebels and W.A. Catterall (1992) Elevated expression of type II Na+ channels in hypomyelinated axons of shiverer mouse brain. J. Neurosci. 12 2259-2267.
68. G.F. Wilson and S.Y. Chiu (1990) Ion channels in axon and Schwann cell membranes at paranodes of mammalian myelinated fibers studied with patch clamp. J. Neurosci. 10 3263-3274.
69. L. Zhou, C.L. Zhang, A. Messing and S.Y. Chiu (1998) Temperature-sensitive neuromuscular transmission in Kv1. 1 null mice: role of potassium channels under the myelin sheath in young nerves. J. Neurosci. 18 7200-7215.