Some benzoxazoles and benzimidazoles as DNA topoisomerase I and II inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 23, Issue 1, 2008, Pages 37-42

  Oksuzoglu, Emine ^a   Tekiner Gulbas, Betul ^b   Alper, Sabiha ^b   Temiz Arpaci, Ozlem ^b   Ertan, Tugba ^b   Yildiz, Ilkay ^b   Diril, Nuran ^a   Sener Aki, Esin ^b   Yalcin, Ismail ^b  

^a HACETTEPE UNIVERSITY   (Turkey)

^b ANKARA UNIVERSITY   (Turkey)

Author keywords

Benzimidazoles; DNA Topoisomerase I; Inhibition, Benzoxazoles; Topoisomerase II

Indexed keywords

2 (4 CHLOROBENZYL)BENZOXAZOLE; 2 (4 NITROBENZYL)BENZOXAZOLE; 2 PHENOXYMETHYLBENZIMIDAZOLE; 5 AMINO 2 (4 BROMOPHENYL)BENZOXAZOLE; 5 AMINO 2 (4 FLUOROPHENYL)BENZOXAZOLE; 5 AMINO 2 PHENYLBENZOXAZOLE; 5 CHLORO 2 (4 METHYLPHENYL)BENZOXAZOLE; 5 NITRO 2 (4 NITROBENZYL)BENZOXAZOLE; 5 NITRO 2 PHENOXYMETHYLBENZIMIDAZOLE; ANTINEOPLASTIC AGENT; BENZIMIDAZOLE DERIVATIVE; BENZOXAZOLE DERIVATIVE; CAMPTOTHECIN; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE INHIBITOR; ETOPOSIDE; GYRASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CELL FREE SYSTEM; CONTROLLED STUDY; DRUG DESIGN; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

BENZIMIDAZOLES; BENZOXAZOLES; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; ENZYME INHIBITORS; ETOPOSIDE; HUMANS; KINETICS; STRUCTURE-ACTIVITY RELATIONSHIP;

EUKARYOTA;

EID: 39349091825     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.1080/14756360701342516     Document Type: Article

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