메뉴 건너뛰기




Volumn 9, Issue , 2008, Pages

Genetic and genomic analysis modeling of germline c-MYC overexpression and cancer susceptibility

(17)  Solé, Xavier a   Hernández, Pilar a   de Heredia, Miguel López b,c   Armengol, Lluís d   Rodríguez Santiago, Benjamín c,e   Gómez, Laia a   Maxwell, Christopher A a   Aguiló, Fernando f   Condom, Enric f   Abril, Jesús b   Pérez Jurado, Luis c,e,g   Estivill, Xavier d   Nunes, Virginia b,c,h   Capellá, Gabriel a   Gruber, Stephen B i   Moreno, Víctor a   Pujana, Miguel Angel a  


Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 6; MYC PROTEIN; TUMOR SUPPRESSOR PROTEIN; UVOMORULIN; KLF6 PROTEIN, HUMAN; ONCOPROTEIN; UNCLASSIFIED DRUG;

EID: 39149134006     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-9-12     Document Type: Article
Times cited : (28)

References (70)
  • 14
    • 0033568130 scopus 로고    scopus 로고
    • Clinical significance of alterations of chromosome 8 in high-grade, advanced, nonmetastatic prostate carcinoma
    • 10.1093/jnci/91.18.1574 10491435
    • Sato K Qian J Slezak JM Lieber MM Bostwick DG Bergstralh EJ Jenkins RB Clinical significance of alterations of chromosome 8 in high-grade, advanced, nonmetastatic prostate carcinoma J Natl Cancer Inst 1999, 91(18):1574-1580. 10.1093/jnci/91.18.1574 10491435
    • (1999) J Natl Cancer Inst , vol.91 , Issue.18 , pp. 1574-1580
    • Sato, K.1    Qian, J.2    Slezak, J.M.3    Lieber, M.M.4    Bostwick, D.G.5    Bergstralh, E.J.6    Jenkins, R.B.7
  • 15
    • 18644366530 scopus 로고    scopus 로고
    • Unopposed c-MYC expression in benign prostatic epithelium causes a cancer phenotype
    • 10.1002/pros.20200 15937962
    • Williams K Fernandez S Stien X Ishii K Love HD Lau YF Roberts RL Hayward SW Unopposed c-MYC expression in benign prostatic epithelium causes a cancer phenotype Prostate 2005, 63(4):369-384. 10.1002/pros.20200 15937962
    • (2005) Prostate , vol.63 , Issue.4 , pp. 369-384
    • Williams, K.1    Fernandez, S.2    Stien, X.3    Ishii, K.4    Love, H.D.5    Lau, Y.F.6    Roberts, R.L.7    Hayward, S.W.8
  • 17
    • 16844371813 scopus 로고    scopus 로고
    • Immortalization of primary human prostate epithelial cells by c-Myc
    • 10.1158/0008-5472.CAN-03-4030 15781629
    • Gil J Kerai P Lleonart M Bernard D Cigudosa JC Peters G Carnero A Beach D Immortalization of primary human prostate epithelial cells by c-Myc Cancer Res 2005, 65(6):2179-2185. 10.1158/0008-5472.CAN-03-4030 15781629
    • (2005) Cancer Res , vol.65 , Issue.6 , pp. 2179-2185
    • Gil, J.1    Kerai, P.2    Lleonart, M.3    Bernard, D.4    Cigudosa, J.C.5    Peters, G.6    Carnero, A.7    Beach, D.8
  • 18
    • 33244496170 scopus 로고    scopus 로고
    • Identification of somatic and germline mitochondrial DNA sequence variants in prostate cancer patients
    • 16472830
    • Gomez-Zaera M Abril J Gonzalez L Aguilo F Condom E Nadal M Nunes V Identification of somatic and germline mitochondrial DNA sequence variants in prostate cancer patients Mutat Res 2006, 595(1-2):42-51. 16472830
    • (2006) Mutat Res , vol.595 , Issue.1-2 , pp. 42-51
    • Gomez-Zaera, M.1    Abril, J.2    Gonzalez, L.3    Aguilo, F.4    Condom, E.5    Nadal, M.6    Nunes, V.7
  • 19
    • 34447559721 scopus 로고    scopus 로고
    • Aneuploidy of chromosome Y in prostate tumors and seminal vesicles: A possible sign of aging rather than an indicator of carcinogenesis?
    • 10.1002/mc.20301 17295237
    • Nadal M Pera G Pujadas J Abril J Gonzalez L Aguilo F Condom E Gomez-Zaera M Nunes V Aneuploidy of chromosome Y in prostate tumors and seminal vesicles: A possible sign of aging rather than an indicator of carcinogenesis? Mol Carcinog 2007, 46(7):543-552. 10.1002/mc.20301 17295237
    • (2007) Mol Carcinog , vol.46 , Issue.7 , pp. 543-552
    • Nadal, M.1    Pera, G.2    Pujadas, J.3    Abril, J.4    Gonzalez, L.5    Aguilo, F.6    Condom, E.7    Gomez-Zaera, M.8    Nunes, V.9
  • 20
    • 0035328474 scopus 로고    scopus 로고
    • Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer
    • 11325816
    • Linja MJ Savinainen KJ Saramaki OR Tammela TL Vessella RL Visakorpi T Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer Cancer Res 2001, 61(9):3550-3555. 11325816
    • (2001) Cancer Res , vol.61 , Issue.9 , pp. 3550-3555
    • Linja, M.J.1    Savinainen, K.J.2    Saramaki, O.R.3    Tammela, T.L.4    Vessella, R.L.5    Visakorpi, T.6
  • 21
    • 1942520992 scopus 로고    scopus 로고
    • Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes in breast and prostate cancer
    • 10.1038/sj.bjc.6601648 14997205
    • Savinainen KJ Linja MJ Saramaki OR Tammela TL Chang GT Brinkmann AO Visakorpi T Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes in breast and prostate cancer Br J Cancer 2004, 90(5):1041-1046. 10.1038/sj.bjc.6601648 14997205
    • (2004) Br J Cancer , vol.90 , Issue.5 , pp. 1041-1046
    • Savinainen, K.J.1    Linja, M.J.2    Saramaki, O.R.3    Tammela, T.L.4    Chang, G.T.5    Brinkmann, A.O.6    Visakorpi, T.7
  • 24
    • 34047244898 scopus 로고    scopus 로고
    • The common variant rs1447295 on chromosome 8q24 and prostate cancer risk: Results from an Australian population-based case-control study
    • 10.1158/1055-9965.EPI-06-0872 17372260
    • Severi G Hayes VM Padilla EJ English DR Southey MC Sutherland RL Hopper JL Giles GG The common variant rs1447295 on chromosome 8q24 and prostate cancer risk: Results from an Australian population-based case-control study Cancer Epidemiol Biomarkers Prev 2007, 16(3):610-612. 10.1158/ 1055-9965.EPI-06-0872 17372260
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , Issue.3 , pp. 610-612
    • Severi, G.1    Hayes, V.M.2    Padilla, E.J.3    English, D.R.4    Southey, M.C.5    Sutherland, R.L.6    Hopper, J.L.7    Giles, G.G.8
  • 26
    • 0023567017 scopus 로고
    • Enhanced expression of the c-myc protooncogene in high-grade human prostate cancers
    • 10.1002/pros.2990110405 2446300
    • Buttyan R Sawczuk IS Benson MC Siegal JD Olsson CA Enhanced expression of the c-myc protooncogene in high-grade human prostate cancers Prostate 1987, 11(4):327-337. 10.1002/pros.2990110405 2446300
    • (1987) Prostate , vol.11 , Issue.4 , pp. 327-337
    • Buttyan, R.1    Sawczuk, I.S.2    Benson, M.C.3    Siegal, J.D.4    Olsson, C.A.5
  • 29
    • 0842278571 scopus 로고    scopus 로고
    • An integrated database of genes responsive to the Myc oncogenic transcription factor: Identification of direct genomic targets
    • 328458 14519204 10.1186/gb-2003-4-10-r69
    • Zeller KI Jegga AG Aronow BJ O'Donnell KA Dang CV An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets Genome Biol 2003, 4(10):R69. 328458 14519204 10.1186/gb-2003-4-10-r69
    • (2003) Genome Biol , vol.4 , Issue.10
    • Zeller, K.I.1    Jegga, A.G.2    Aronow, B.J.3    O'Donnell, K.A.4    Dang, C.V.5
  • 31
    • 0030603221 scopus 로고    scopus 로고
    • Characterization of new human c-myc mRNA species produced by alternative splicing
    • 10.1016/0378-1119(96)00464-7 8863737
    • Bodescot M Brison O Characterization of new human c-myc mRNA species produced by alternative splicing Gene 1996, 174(1):115-120. 10.1016/ 0378-1119(96)00464-7 8863737
    • (1996) Gene , vol.174 , Issue.1 , pp. 115-120
    • Bodescot, M.1    Brison, O.2
  • 34
    • 2142717404 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of prostate cancer
    • 362118 15067324 10.1172/JCI200420032
    • Glinsky GV Glinskii AB Stephenson AJ Hoffman RM Gerald WL Gene expression profiling predicts clinical outcome of prostate cancer J Clin Invest 2004, 113(6):913-923. 362118 15067324 10.1172/JCI200420032
    • (2004) J Clin Invest , vol.113 , Issue.6 , pp. 913-923
    • Glinsky, G.V.1    Glinskii, A.B.2    Stephenson, A.J.3    Hoffman, R.M.4    Gerald, W.L.5
  • 38
    • 34347358573 scopus 로고    scopus 로고
    • In vivo regulation of p21 by the Kruppel-like factor 6 tumor-suppressor gene in mouse liver and human hepatocellular carcinoma
    • 10.1038/sj.onc.1210223 17297474
    • Narla G Kremer-Tal S Matsumoto N Zhao X Yao S Kelley K Tarocchi M Friedman SL In vivo regulation of p21 by the Kruppel-like factor 6 tumor-suppressor gene in mouse liver and human hepatocellular carcinoma Oncogene 2007, 26(30):4428-4434. 10.1038/sj.onc.1210223 17297474
    • (2007) Oncogene , vol.26 , Issue.30 , pp. 4428-4434
    • Narla, G.1    Kremer-Tal, S.2    Matsumoto, N.3    Zhao, X.4    Yao, S.5    Kelley, K.6    Tarocchi, M.7    Friedman, S.L.8
  • 39
    • 0036899513 scopus 로고    scopus 로고
    • The genetics of variation in gene expression
    • 10.1038/ng1036 12454648
    • Cheung VG Spielman RS The genetics of variation in gene expression Nat Genet 2002, 32(Suppl):522-525. 10.1038/ng1036 12454648
    • (2002) Nat Genet , vol.32 , Issue.SUPPL. , pp. 522-525
    • Cheung, V.G.1    Spielman, R.S.2
  • 40
    • 5444256188 scopus 로고    scopus 로고
    • Allele-specific gene expression differences in humans
    • 10.1093/hmg/ddh227 Spec No 2
    • Buckland PR Allele-specific gene expression differences in humans Hum Mol Genet 2004, 13: Spec No 2 R255-60. 10.1093/hmg/ddh227 15358732
    • (2004) Hum Mol Genet , vol.13
    • Buckland, P.R.1
  • 41
    • 33846631884 scopus 로고    scopus 로고
    • Common genetic variants account for differences in gene expression among ethnic groups
    • 10.1038/ng1955 17206142
    • Spielman RS Bastone LA Burdick JT Morley M Ewens WJ Cheung VG Common genetic variants account for differences in gene expression among ethnic groups Nat Genet 2007, 39(2):226-231. 10.1038/ng1955 17206142
    • (2007) Nat Genet , vol.39 , Issue.2 , pp. 226-231
    • Spielman, R.S.1    Bastone, L.A.2    Burdick, J.T.3    Morley, M.4    Ewens, W.J.5    Cheung, V.G.6
  • 43
    • 11944271042 scopus 로고
    • Overexpression of the N-ras proto-oncogene, not somatic mutational activation, associated with malignant tumors in transgenic mice
    • 1328989
    • Mangues R Seidman I Gordon JW Pellicer A Overexpression of the N-ras proto-oncogene, not somatic mutational activation, associated with malignant tumors in transgenic mice Oncogene 1992, 7(10):2073-2076. 1328989
    • (1992) Oncogene , vol.7 , Issue.10 , pp. 2073-2076
    • Mangues, R.1    Seidman, I.2    Gordon, J.W.3    Pellicer, A.4
  • 45
    • 0021720781 scopus 로고
    • Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes
    • 10.1016/0092-8674(84)90257-5 6488314
    • Stewart TA Pattengale PK Leder P Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes Cell 1984, 38(3):627-637. 10.1016/0092-8674(84)90257-5 6488314
    • (1984) Cell , vol.38 , Issue.3 , pp. 627-637
    • Stewart, T.A.1    Pattengale, P.K.2    Leder, P.3
  • 46
    • 0022497717 scopus 로고
    • Consequences of widespread deregulation of the c-myc gene in transgenic mice: Multiple neoplasms and normal development
    • 10.1016/0092-8674(86)90280-1 3011271
    • Leder A Pattengale PK Kuo A Stewart TA Leder P Consequences of widespread deregulation of the c-myc gene in transgenic mice: Multiple neoplasms and normal development Cell 1986, 45(4):485-495. 10.1016/ 0092-8674(86)90280-1 3011271
    • (1986) Cell , vol.45 , Issue.4 , pp. 485-495
    • Leder, A.1    Pattengale, P.K.2    Kuo, A.3    Stewart, T.A.4    Leder, P.5
  • 47
    • 34247641243 scopus 로고    scopus 로고
    • Integration of genome and chromatin structure with gene expression profiles to predict c-MYC recognition site binding and function
    • 1847699 17411336 10.1371/journal.pcbi.0030063
    • Chen Y Blackwell TW Chen J Gao J Lee AW States DJ Integration of genome and chromatin structure with gene expression profiles to predict c-MYC recognition site binding and function PLoS Comput Biol 2007, 3(4):e63. 1847699 17411336 10.1371/journal.pcbi.0030063
    • (2007) PLoS Comput Biol , vol.3 , Issue.4
    • Chen, Y.1    Blackwell, T.W.2    Chen, J.3    Gao, J.4    Lee, A.W.5    States, D.J.6
  • 48
    • 0346690367 scopus 로고    scopus 로고
    • Myc confers androgen-independent prostate cancer cell growth
    • 281646 14660748 10.1172/JCI200319035
    • Bernard D Pourtier-Manzanedo A Gil J Beach DH Myc confers androgen-independent prostate cancer cell growth J Clin Invest 2003, 112(11):1724-1731. 281646 14660748 10.1172/JCI200319035
    • (2003) J Clin Invest , vol.112 , Issue.11 , pp. 1724-1731
    • Bernard, D.1    Pourtier-Manzanedo, A.2    Gil, J.3    Beach, D.H.4
  • 49
    • 33947305781 scopus 로고    scopus 로고
    • ARACNE: An algorithm for the reconstruction of gene regulatory networks in a mammalian cellular context
    • 1810318 16723010 10.1186/1471-2105-7-S1-S7
    • Margolin AA Nemenman I Basso K Wiggins C Stolovitzky G Dalla Favera R Califano A ARACNE: An algorithm for the reconstruction of gene regulatory networks in a mammalian cellular context BMC Bioinformatics 2006, 7(Suppl 1):S7. 1810318 16723010 10.1186/1471-2105-7-S1-S7
    • (2006) BMC Bioinformatics , vol.7 , Issue.SUPPL. 1
    • Margolin, A.A.1    Nemenman, I.2    Basso, K.3    Wiggins, C.4    Stolovitzky, G.5    Dalla Favera, R.6    Califano, A.7
  • 52
    • 0012508834 scopus 로고    scopus 로고
    • Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma
    • 10.1016/S1535-6108(02)00215-5 12498717
    • Yamashita K Upadhyay S Osada M Hoque MO Xiao Y Mori M Sato F Meltzer SJ Sidransky D Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma Cancer Cell 2002, 2(6):485-495. 10.1016/S1535-6108(02)00215-5 12498717
    • (2002) Cancer Cell , vol.2 , Issue.6 , pp. 485-495
    • Yamashita, K.1    Upadhyay, S.2    Osada, M.3    Hoque, M.O.4    Xiao, Y.5    Mori, M.6    Sato, F.7    Meltzer, S.J.8    Sidransky, D.9
  • 53
    • 0038174752 scopus 로고    scopus 로고
    • KLF6, a putative tumor suppressor gene, is mutated in astrocytic gliomas
    • 10.1002/ijc.11123 12740910
    • Jeng YM Hsu HC KLF6, a putative tumor suppressor gene, is mutated in astrocytic gliomas Int J Cancer 2003, 105(5):625-629. 10.1002/ijc.11123 12740910
    • (2003) Int J Cancer , vol.105 , pp. 625-629
    • Jeng, Y.M.1    Hsu, H.C.2
  • 56
    • 2542521484 scopus 로고    scopus 로고
    • Kruppel-like factor 6 is frequently down-regulated and induces apoptosis in non-small cell lung cancer cells
    • 10.1158/0008-5472.CAN-04-0185 15172991
    • Ito G Uchiyama M Kondo M Mori S Usami N Maeda O Kawabe T Hasegawa Y Shimokata K Sekido Y Kruppel-like factor 6 is frequently down-regulated and induces apoptosis in non-small cell lung cancer cells Cancer Res 2004 64 11 3838 3843 10.1158/0008-5472.CAN-04-0185 15172991
    • (2004) Cancer Res , vol.64 , pp. 3838-3843
    • Ito, G.1    Uchiyama, M.2    Kondo, M.3    Mori, S.4    Usami, N.5    Maeda, O.6    Kawabe, T.7    Hasegawa, Y.8    Shimokata, K.9    Sekido, Y.10
  • 59
    • 0030811614 scopus 로고    scopus 로고
    • Aberrant E-cadherin and alpha-catenin expression in prostate cancer: Correlation with patient survival
    • 9242448
    • Richmond PJ Karayiannakis AJ Nagafuchi A Kaisary AV Pignatelli M Aberrant E-cadherin and alpha-catenin expression in prostate cancer: correlation with patient survival Cancer Res 1997, 57(15):3189-3193. 9242448
    • (1997) Cancer Res , vol.57 , Issue.15 , pp. 3189-3193
    • Richmond, P.J.1    Karayiannakis, A.J.2    Nagafuchi, A.3    Kaisary, A.V.4    Pignatelli, M.5
  • 63
    • 34247591993 scopus 로고    scopus 로고
    • Multiple prostate cancer risk variants on 8q24
    • 10.1038/ng0507-579 17460686
    • Witte JS Multiple prostate cancer risk variants on 8q24 Nat Genet 2007, 39(5):579-580. 10.1038/ng0507-579 17460686
    • (2007) Nat Genet , vol.39 , Issue.5 , pp. 579-580
    • Witte, J.S.1
  • 66
    • 34547974859 scopus 로고    scopus 로고
    • Involvement of Kruppel-like factor 6 (KLF6) mutation in the development of nonpolypoid colorectal carcinoma
    • 17663506
    • Mukai S Hiyama T Tanaka S Yoshihara M Arihiro K Chayama K Involvement of Kruppel-like factor 6 (KLF6) mutation in the development of nonpolypoid colorectal carcinoma World J Gastroenterol 2007, 13(29):3932-3938. 17663506
    • (2007) World J Gastroenterol , vol.13 , Issue.29 , pp. 3932-3938
    • Mukai, S.1    Hiyama, T.2    Tanaka, S.3    Yoshihara, M.4    Arihiro, K.5    Chayama, K.6
  • 67
    • 34247115114 scopus 로고    scopus 로고
    • Difference in the role of loss of heterozygosity at 10p15 (KLF6 locus) in colorectal carcinogenesis between sporadic and familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer patients
    • 10.1159/000100523 17347589
    • Miyaki M Yamaguchi T Iijima T Funata N Mori T Difference in the role of loss of heterozygosity at 10p15 (KLF6 locus) in colorectal carcinogenesis between sporadic and familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer patients Oncology 2006M 71(1-2):131-135. 10.1159/000100523 17347589
    • (2006) Oncology , vol.71 , Issue.1-2 , pp. 131-135
    • Miyaki, M.1    Yamaguchi, T.2    Iijima, T.3    Funata, N.4    Mori, T.5
  • 68
    • 34047179603 scopus 로고    scopus 로고
    • SNPassoc: An R package to perform whole genome association studies
    • 10.1093/bioinformatics/btm025 17267436
    • Gonzalez JR Armengol L Sole X Guino E Mercader JM Estivill X Moreno V SNPassoc: An R package to perform whole genome association studies Bioinformatics 2007, 23(5):644-645. 10.1093/bioinformatics/btm025 17267436
    • (2007) Bioinformatics , vol.23 , Issue.5 , pp. 644-645
    • Gonzalez, J.R.1    Armengol, L.2    Sole, X.3    Guino, E.4    Mercader, J.M.5    Estivill, X.6    Moreno, V.7
  • 69
    • 33747827929 scopus 로고    scopus 로고
    • SNPStats: A web tool for the analysis of association studies
    • 10.1093/bioinformatics/btl268 16720584
    • Sole X Guino E Valls J Iniesta R Moreno V SNPStats: A web tool for the analysis of association studies Bioinformatics 2006, 22(15):1928-1929. 10.1093/bioinformatics/btl268 16720584
    • (2006) Bioinformatics , vol.22 , Issue.15 , pp. 1928-1929
    • Sole, X.1    Guino, E.2    Valls, J.3    Iniesta, R.4    Moreno, V.5
  • 70
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • 10.1093/bioinformatics/bth457 15297300
    • Barrett JC Fry B Maller J Daly MJ Haploview: Analysis and visualization of LD and haplotype maps Bioinformatics 2005, 21(2):263-265. 10.1093/ bioinformatics/bth457 15297300
    • (2005) Bioinformatics , vol.21 , Issue.2 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.