-
1
-
-
0035424901
-
Decreased expression of toll-like receptor 4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide
-
Abreu M., Vora P., Faure E., Thomas L.S., Arnold E.T., and Arditi M. Decreased expression of toll-like receptor 4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide. Journal of Immunology 167 (2001) 1609-1617
-
(2001)
Journal of Immunology
, vol.167
, pp. 1609-1617
-
-
Abreu, M.1
Vora, P.2
Faure, E.3
Thomas, L.S.4
Arnold, E.T.5
Arditi, M.6
-
2
-
-
33646055526
-
Trypsin-sensitive modulation of intestinal epithelial MD-2 as mechanism of lipopolysaccharide tolerance
-
Cario E., Golenbock D.T., Visintin A., Runzi M., Gerken G., and Podolsky D.K. Trypsin-sensitive modulation of intestinal epithelial MD-2 as mechanism of lipopolysaccharide tolerance. Journal of Immunology 176 (2006) 4258-4266
-
(2006)
Journal of Immunology
, vol.176
, pp. 4258-4266
-
-
Cario, E.1
Golenbock, D.T.2
Visintin, A.3
Runzi, M.4
Gerken, G.5
Podolsky, D.K.6
-
3
-
-
0035877718
-
Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. Transfer from CD14 to TLR4 and MD-2
-
Da Silva Correia J., Soldau K., Christen U., Tobias P.S., and Ulevitch R.J. Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. Transfer from CD14 to TLR4 and MD-2. Journal of Biological Chemistry 276 (2001) 21129-21135
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 21129-21135
-
-
Da Silva Correia, J.1
Soldau, K.2
Christen, U.3
Tobias, P.S.4
Ulevitch, R.J.5
-
4
-
-
0029586031
-
Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease
-
Duchmann R., Kaiser I., Hermann E., Mayet W., Ewe K., and Meyer zum Buschenfelde K.H. Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease. Clinical and Experimental Immunology 102 (1995) 445-447
-
(1995)
Clinical and Experimental Immunology
, vol.102
, pp. 445-447
-
-
Duchmann, R.1
Kaiser, I.2
Hermann, E.3
Mayet, W.4
Ewe, K.5
Meyer zum Buschenfelde, K.H.6
-
5
-
-
0035253732
-
MD-2 enables toll-like receptor 2 (TLR2)-mediated responses to lipopolysaccharide and enhances TLR2-mediated responses to gram-negative bacteria and their cell wall components
-
Dziarski R., Wang Q., Miyake K., Kirschning C.J., and Gupta D. MD-2 enables toll-like receptor 2 (TLR2)-mediated responses to lipopolysaccharide and enhances TLR2-mediated responses to gram-negative bacteria and their cell wall components. Journal of Immunology 166 (2001) 1938-1944
-
(2001)
Journal of Immunology
, vol.166
, pp. 1938-1944
-
-
Dziarski, R.1
Wang, Q.2
Miyake, K.3
Kirschning, C.J.4
Gupta, D.5
-
6
-
-
0037018107
-
Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells
-
Hornef M.W., Frisan T., Vandewalle A., Normark S., and Richter-Dahlfors A. Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells. Journal of Experimental Medicine 195 (2002) 559-570
-
(2002)
Journal of Experimental Medicine
, vol.195
, pp. 559-570
-
-
Hornef, M.W.1
Frisan, T.2
Vandewalle, A.3
Normark, S.4
Richter-Dahlfors, A.5
-
7
-
-
0036494318
-
Cyclooxygenase-2 activity altered the cell-surface carbohydrate antigens on colon cancer cells and enhanced liver metastasis
-
Kakiuchi Y., Tsuji S., Tsujii M., Murata H., Kawai N., Yasumaru M., Kimura A., Komori M., Irie T., Miyoshi E., Sasaki Y., Hayashi N., Kawano S., and Hori M. Cyclooxygenase-2 activity altered the cell-surface carbohydrate antigens on colon cancer cells and enhanced liver metastasis. Cancer Research 62 (2002) 1567-1572
-
(2002)
Cancer Research
, vol.62
, pp. 1567-1572
-
-
Kakiuchi, Y.1
Tsuji, S.2
Tsujii, M.3
Murata, H.4
Kawai, N.5
Yasumaru, M.6
Kimura, A.7
Komori, M.8
Irie, T.9
Miyoshi, E.10
Sasaki, Y.11
Hayashi, N.12
Kawano, S.13
Hori, M.14
-
8
-
-
23244444701
-
Oncogenic potential of MEK1 in rat intestinal epithelial cells is mediated via cyclooxygenase-2
-
Komatsu K., Buchanan F.G., Katkury S., Morrow J.D., Inoue H., Otaka M., Watanabe S., and DuBois R.N. Oncogenic potential of MEK1 in rat intestinal epithelial cells is mediated via cyclooxygenase-2. Gastroenterology 129 (2005) 577-590
-
(2005)
Gastroenterology
, vol.129
, pp. 577-590
-
-
Komatsu, K.1
Buchanan, F.G.2
Katkury, S.3
Morrow, J.D.4
Inoue, H.5
Otaka, M.6
Watanabe, S.7
DuBois, R.N.8
-
9
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis J.M., and Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiological Reviews 81 (2001) 807-869
-
(2001)
Physiological Reviews
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
10
-
-
0036838930
-
Dysregulation of LPS-induced toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin tolerant cells
-
Medvedev A.E., Lentschat A., Wahl L.M., Golenbock D.T., and Vogel S.N. Dysregulation of LPS-induced toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin tolerant cells. Journal of Immunology 169 (2002) 5209-5216
-
(2002)
Journal of Immunology
, vol.169
, pp. 5209-5216
-
-
Medvedev, A.E.1
Lentschat, A.2
Wahl, L.M.3
Golenbock, D.T.4
Vogel, S.N.5
-
11
-
-
0030831210
-
A human homologue of the Drosophilla Toll protein signals activation of adaptive immunity
-
Medzhitov R., Preston-Hurlburt P., and Janeway Jr. C.A. A human homologue of the Drosophilla Toll protein signals activation of adaptive immunity. Nature 388 (1997) 394-397
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
12
-
-
0037388127
-
The role of disulfide bonds in the assembly and function of MD-2
-
Mullen G.E.D., Kennedy M.N., Visintin A., Mazzoni A., Leifer C.A., Davis D.R., and Segal D.M. The role of disulfide bonds in the assembly and function of MD-2. Proceedings of the National Academy of Sciences USA 100 (2003) 3919-3924
-
(2003)
Proceedings of the National Academy of Sciences USA
, vol.100
, pp. 3919-3924
-
-
Mullen, G.E.D.1
Kennedy, M.N.2
Visintin, A.3
Mazzoni, A.4
Leifer, C.A.5
Davis, D.R.6
Segal, D.M.7
-
13
-
-
0036301797
-
Essential role of MD-2 in LPS responsiveness and TLR4 distribution
-
Nagai Y., Akashi S., Nagafuku M., Ogata M., Iwakura Y., Akira S., Kitamura T., Kosugi A., Kimoto M., and Miyake K. Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nature Immunology 3 (2002) 667-672
-
(2002)
Nature Immunology
, vol.3
, pp. 667-672
-
-
Nagai, Y.1
Akashi, S.2
Nagafuku, M.3
Ogata, M.4
Iwakura, Y.5
Akira, S.6
Kitamura, T.7
Kosugi, A.8
Kimoto, M.9
Miyake, K.10
-
14
-
-
0034075754
-
The IL-1 receptor/toll-like receptor superfamily:crutial receptors for inflammation and host defense
-
O'Neill L.A.J., and Dinarello C.A. The IL-1 receptor/toll-like receptor superfamily:crutial receptors for inflammation and host defense. Immunology Today 21 (2000) 206-209
-
(2000)
Immunology Today
, vol.21
, pp. 206-209
-
-
O'Neill, L.A.J.1
Dinarello, C.A.2
-
15
-
-
1842583729
-
Mechanisms of cross hyporesponsiveness to toll-like receptor bacterial ligands in intestinal epithelial cells
-
Otte J.M., Cario E., and Podolsky D.K. Mechanisms of cross hyporesponsiveness to toll-like receptor bacterial ligands in intestinal epithelial cells. Gastroenterology 128 (2004) 1054-1070
-
(2004)
Gastroenterology
, vol.128
, pp. 1054-1070
-
-
Otte, J.M.1
Cario, E.2
Podolsky, D.K.3
-
16
-
-
33744517892
-
Cox-2 and gastric cancer: more on inflammation and neoplasia
-
Potter J.D., and Ulrich C.M. Cox-2 and gastric cancer: more on inflammation and neoplasia. Gastroenterology 130 (2006) 2198-2200
-
(2006)
Gastroenterology
, vol.130
, pp. 2198-2200
-
-
Potter, J.D.1
Ulrich, C.M.2
-
17
-
-
10244229656
-
Soluble MD-2 activity in plasma from patients with severe sepsis and septic shock
-
Pugin J., Stem-Voeffray S., Daubeuf B., Matthay M.A., and Elson G. Soluble MD-2 activity in plasma from patients with severe sepsis and septic shock. Blood 104 (2004) 4071-4079
-
(2004)
Blood
, vol.104
, pp. 4071-4079
-
-
Pugin, J.1
Stem-Voeffray, S.2
Daubeuf, B.3
Matthay, M.A.4
Elson, G.5
-
18
-
-
0033532629
-
MD-2, a molecule that confers lipopolysaccharide responsiveness on toll-like receptor 4
-
Shimazu R., Akashi S., Ogata H., Nagai Y., Fukudome K., Miyake K., and Kimoto M. MD-2, a molecule that confers lipopolysaccharide responsiveness on toll-like receptor 4. Journal of Experimental Medicine 189 (1999) 1777-1782
-
(1999)
Journal of Experimental Medicine
, vol.189
, pp. 1777-1782
-
-
Shimazu, R.1
Akashi, S.2
Ogata, H.3
Nagai, Y.4
Fukudome, K.5
Miyake, K.6
Kimoto, M.7
-
19
-
-
4143107932
-
Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition
-
Simmons D.L., Botting R.M., and Hla T. Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition. Pharmacological Reviews 56 (2004) 387-437
-
(2004)
Pharmacological Reviews
, vol.56
, pp. 387-437
-
-
Simmons, D.L.1
Botting, R.M.2
Hla, T.3
-
20
-
-
0033782189
-
ets-2 is a target for an akt (protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice
-
Smith J.L., Schaffner A.E., Hofmeister J.K., Hartman M., We G., Forsthoefel D., Hume D.A., and Ostrowski M.C. ets-2 is a target for an akt (protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice. Molecular and Cellular Biology 20 (2000) 8020-8034
-
(2000)
Molecular and Cellular Biology
, vol.20
, pp. 8020-8034
-
-
Smith, J.L.1
Schaffner, A.E.2
Hofmeister, J.K.3
Hartman, M.4
We, G.5
Forsthoefel, D.6
Hume, D.A.7
Ostrowski, M.C.8
-
21
-
-
0030881742
-
Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation: glucocorticoids inhibit TNF-alpha translation by blocking JNK/SAPK
-
Swantek J.L., Cobb M.H., and Geppert T.D. Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation: glucocorticoids inhibit TNF-alpha translation by blocking JNK/SAPK. Molecular and Cellular Biology 17 (1997) 6274-6282
-
(1997)
Molecular and Cellular Biology
, vol.17
, pp. 6274-6282
-
-
Swantek, J.L.1
Cobb, M.H.2
Geppert, T.D.3
-
25
-
-
0032997542
-
Recognition of Gram-negative bacteria and endotoxin by the innate immune system
-
Ulevitch R.J., and Tobias P.S. Recognition of Gram-negative bacteria and endotoxin by the innate immune system. Current Opinion in Immunology 11 (1999) 19-22
-
(1999)
Current Opinion in Immunology
, vol.11
, pp. 19-22
-
-
Ulevitch, R.J.1
Tobias, P.S.2
-
26
-
-
0035834135
-
Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to toll-like receptor 4
-
Visintin A., Mazzoni A., Spitzer J.A., and Segal D.A. Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to toll-like receptor 4. Proceedings of the National Academy of Sciences USA 98 (2001) 12156-12161
-
(2001)
Proceedings of the National Academy of Sciences USA
, vol.98
, pp. 12156-12161
-
-
Visintin, A.1
Mazzoni, A.2
Spitzer, J.A.3
Segal, D.A.4
-
27
-
-
0034008927
-
Transcriptional activation of the cyclooxygenase-2 gene in endotoxin-treated RAW 264.7 macrophages
-
Wadleigh D.J., Reddy S.T., Kopp E., Ghosh S., and Herschman H.R. Transcriptional activation of the cyclooxygenase-2 gene in endotoxin-treated RAW 264.7 macrophages. Journal of Biological Chemistry 275 (2000) 6259-6266
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 6259-6266
-
-
Wadleigh, D.J.1
Reddy, S.T.2
Kopp, E.3
Ghosh, S.4
Herschman, H.R.5
-
28
-
-
0034617274
-
Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4
-
Yang H., Young D.W., Gusovsky F., and Chow J.C. Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4. Journal of Biological Chemistry 275 (2000) 20861-20866
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 20861-20866
-
-
Yang, H.1
Young, D.W.2
Gusovsky, F.3
Chow, J.C.4
|