Micronutrient supplementation for cancer patients. Rationale for recommendations;Mikronährstoffsupplemente bei onkologischen patienten. Rationale für die empfehlung

Onkologe

Volumn 14, Issue 1, 2008, Pages 45-57

  Biesalski, H K ^a,b  

^a UNIVERSITY OF STUTTGART   (Germany)

^b UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

Antioxidants; Cancer; Malnutrition; Micronutrients; Radio chemotherapy

Indexed keywords

ANTINEOPLASTIC AGENT; ANTIOXIDANT; MINERAL; MULTIVITAMIN; TRACE ELEMENT;

ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER RISK; DIETARY REFERENCE INTAKE; HUMAN; MALNUTRITION; NEOPLASM; NUTRIENT SUPPLY;

EID: 39149119629     PISSN: 09478965     EISSN: 14330415     Source Type: Journal    
DOI: 10.1007/s00761-007-1291-z     Document Type: Article

References (81)

1. Anthony HM, Schorah CJ (1982) Severe hypovitaminosis C in lung-cancer patients: the utilization of vitamin C in surgical repair and lymphocyte-related host resistance. Br J Cancer 46: 354-367
2. Argyriou AA, Chroni E, Koutras A et al. (2006) A randomized controlled trial evaluating the efficacy and safety of vitamin E supplementation for protection against cisplatin-induced peripheral neuropathy: final results. Support Care Cancer 14: 1134-1140
3. Argyriou AA, Chroni E, Koutras A et al. (2005) Vitamin E for prophylaxis against chemotherapy-induced neuropathy: a randomized controlled trial. Neurology 64: 26-31
4. Assouline S, Miller WH (2006) High-dose vitamin C therapy: renewed hope or false promise? CMAJ 174: 956-957
5. Besa EC, Abrahm JL, Bartholomew MJ et al. (1990) Treatment with 13-cis-retinoic acid in transfusion-dependent patients with myelodysplastic syndrome and decreased toxicity with addition of alpha-tocopherol. Am J Med 89: 739-747
6. Block KI, Koch AC, Mead MN et al. (2007) Impact of antioxidant supplementation on chemotherapeutic efficacy: a systematic review of the evidence from randomized controlled trials. Cancer Treat Rev 33: 407-418
7. Borek C (2004) Antioxidants and radiation therapy. J Nutr 134: 3207S-3209S
8. Bryan J, Calvaresi E (2004) Associations between dietary intake of folate and vitamins B-12 and B-6 and self-reported cognitive function and psychological well-being in Australian men and women in midlife. J Nutr Health Aging 8: 226-232
9. Cameron E, Pauling L (1976) Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer.Proc Natl Acad Sci U S A 73: 3685-3689
10. Chamras H, Barsky SH, Ardashian A et al. (2005) Novel interactions of vitamin E and estrogen in breast cancer. Nutr Cancer 52: 43-48
11. Daniels JS, Gates KS, Tronche C, Greenberg MM (1998) Direct evidence for bimodal DNA damage induced by tirapazamine. Chem Res Toxicol 11: 1254-1257
12. Luca C de, Deeva I, Mikhal'Chik E, Korkina L (2007) Beneficial effects of pro-/antioxidant-based nutraceuticals in the skin rejuvenation techniques. Cell Mol Biol (Noisy-le-grand) 53: 94-101
13. Delanian S, Lefaix JL (2007) Current management for late normal tissue injury: radiation-induced fibrosis and necrosis. Semin Radiat Oncol 17: 99-107; Review
14. Delanian S, Porcher R, Rudant J, Lefaix JL (2005) Kinetics of response to long-term treatment combining pentoxifylline and tocopherol in patients with superficial radiation-induced fibrosis. J Clin Oncol 23: 8570-8579
15. Souza Fede AB de, Bensi CG, Trufelli DC et al. (2007) Multivitamins do not improve radiation therapy-related fatigue: results of a double-blind randomized crossover trial. Am J Clin Oncol 30: 432-436
16. Dimery IW, Hong WK, Lee JJ et al. (1997) Phase I trial of alpha-tocopherol effects on 13-cis-retinoic acid toxicity. Ann Oncol 8: 85-89
17. Diwadkar-Navsariwala V, Diamond AM (2004) The link between selenium and chemoprevention: a case for selenoproteins. J Nutr 134: 2899-2902
18. Diwadkar-Navsariwala V, Prins GS, Swanson SM et al. (2006) Selenoprotein deficiency accelerates prostate carcinogenesis in a transgenic model. Proc Natl Acad Sci U S A 103: 8179-8184
19. Drisko JA, Chapman J, Hunter VJ (2003) The use of antioxidants with first-line chemotherapy in two cases of ovarian cancer. J Am Coll Nutr 22: 118-123
20. Elango N, Samuel S, Chinnakkannu P (2006) Enzymatic and non-enzymatic antioxidant status in stage (III) human oral squamous cell carcinoma and treated with radical radio therapy: influence of selenium supplementation. Clin Chim Acta 373: 92-98; Epub 2006 May 19
21. Fain O, Mathieu E, Thomas M (1998) Scurvy in patients with cancer. BMJ 316: 1661-1662
22. Federico A, Iodice P, Federico P et al. (2001) Effects of selenium and zinc supplementation on nutritional status in patients with cancer of digestive tract. Eur J Clin Nutr 55: 293-297
23. Fiaschi AI, Cozzolino A, Ruggiero G, Giorgi G (2005) Glutathione, ascorbic acid and antioxidant enzymes in the tumor tissue and blood of patients with oral squamous cell carcinoma. Eur Rev Med Pharmacol Sci 9: 361-367
24. Frank J, Flaccus A, Schwarz C et al. (2006) Ascorbic acid suppresses cell death in rat DS-sarcoma cancer cells induced by 5-aminolevulinic acid-based photodynamic therapy. Free Radic Biol Med 40: 827-836
25. Frank J, Kelleher DK, Pompella A et al. (1998) Enhancement of oxidative cell injury and antitumor effects of localized 44 degrees C hyperthermia upon combination with respiratory hyperoxia and xanthine oxidase. Cancer Res 58: 2693-2698
26. Frank J, Lambert C, Biesalski HK et al. (2003) Intensified oxidative and nitrosative stress following combined ALA-based photodynamic therapy and local hyperthermia in rat tumors. Int J Cancer 107: 941-948
27. Ganser A, Maurer A, Contzen C et al. (1996) Improved multilineage response of hematopoiesis in patients with myelodysplastic syndromes to a combination therapy with all-trans-retinoic acid, granulocyte colony-stimulating factor, erythropoietin and alpha-tocopherol. Ann Hematol 72: 237-244
28. Gatenby RA, Kessler HB, Rosenblum JS et al. (1988) Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy. Int J Radiat Oncol Biol Phys 14: 831-838
29. Goel S, Agarwal SB, Mandal AK et al. (1999) Emerging role of ascorbic acid in the management of advanced breast carcinoma as a chemosensitizer. Asian J Surg 22: 333-336
30. Guo G, Yan-Sanders Y, Lyn-Cook BD et al. (2003) Manganese superoxide dismutase-mediated gene expression in radiation-induced adaptive responses. Mol Cell Biol 23: 2362-2378
31. Hockel M, Knoop C, Schlenger K et al. (1993) Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix. Radiother Oncol 26: 45-50
32. Husbeck B, Peehl DM, Knox SJ (2005) Redox modulation of human prostate carcinoma cells by selenite increases radiation-induced cell killing. Free Radic Biol Med 38: 50-57
33. Israel L, Hajji O, Grefft-Alami A et al. (1985) Vitamin A augmentation of the effects of chemotherapy in metastatic breast cancers after menopause: a randomized trial of 100 patients. Ann Med Interne (Paris) 136: 551-554
34. Jaakkola K, Lahteenmaki P, Laakso J et al. (1992) Treatment with antioxidant and other nutrients in combination with chemotherapy and irradiation in patients with small-cell lung cancer. Anticancer Res 12: 599-606
35. Jarvinen K, Soini Y, Kahlos K, Kinnula VL (2002) Overexpression of gamma-glutamylcysteine synthetase in human malignant mesothelioma. Hum Pathol 33: 748-755
36. Jatoi A, Williams B, Nichols F et al. (2005) Is voluntary vitamin and mineral supplementation associated with better outcome in non-small cell lung cancer patients? Results from the Mayo Clinic lung cancer cohort. Lung Cancer 49: 77-84
37. Kamphuis MH, Geerlings MI, Grobbee DE, Kromhout D (2007) Dietary intake of B(6-9-12) vitamins, serum homocysteine levels and their association with depressive symptoms: the Zutphen Elderly Study. Eur J Clin Nutr
38. Kennedy KA (1987) Hypoxic cells as specific drug targets for chemotherapy. Anticancer Drug Des 2: 181-194
39. Kinnula K, Linnainmaa K, Raivio KO, Kinnula VL (1998) Endogenous antioxidant enzymes and glutathione S-transferase in protection of mesothelioma cells against hydrogen peroxide and epirubicin toxicity. Br J Cancer 77: 1097-1102
40. Kinnula VL, Paakko P, Soini Y (2004) Antioxidant enzymes and redox regulating thiol proteins in malignancies of human lung. FEBS Lett 569: 1-6
41. Kinnula VL, Lehtonen S, Sormunen R et al. (2002) Overexpression of peroxiredoxins I, II, III, V, and VI in malignant mesothelioma. J Pathol 196: 316-323
42. Krasner N, Dymock IW (1974) Ascorbic acid deficiency in malignant diseases: a clinical and biochemical study. Br J Cancer 30: 142-145
43. Kumaraguruparan R, Kabalimoorthy J, Nagini S (2005) Correlation of tissue lipid peroxidation and antioxidants with clinical stage and menopausal status in patients with adenocarcinoma of the breast. Clin Biochem 38: 154-158
44. Kumaraguruparan R, Subapriya R, Viswanathan P, Nagini S (2002) Tissue lipid peroxidation and antioxidant status in patients with adenocarcinoma of the breast. Clin Chim Acta 325: 165-170
45. Kumaraguruparan R, Kabalimoorthy J, Nagini S (2005) Correlation of tissue lipid peroxidation and antioxidants with clinical stage and menopausal status in patients with adenocarcinoma of the breast. Clin Biochem 38: 154-158
46. Lehr HA, Germann G, McGregor GP et al. (2006) Consensus meeting on.,Relevance of parenteral vitamin C in acute endothelial dependent pathophysiological conditions (EDPC)". Eur J Med Res 11: 516-526
47. Leung SW, Mitchell JB, al-Nabulsi I et al. (1993) Effect of L-buthionine sulfoximine on the radiation response of human renal carcinoma cell lines. Cancer 71: 2276-2285
48. Lesperance ML, Olivotto IA, Forde N et al. (2002) Mega-dose vitamins and minerals in the treatment of non-metastatic breast cancer: an historical cohort study. Breast Cancer Res Treat 76: 137-143
49. Li QQ, Wang WJ, Xu JD et al. (2007) Up-regulation of CD147 and matrix metalloproteinase-2, -9 induced by P-glycoprotein substrates in multidrug resistant breast cancer cells. Cancer Sci 98: 1767-1774
50. McGregor GP, Biesalski HK (2006) Rationale and impact of vitamin C in clinical nutrition. Curr Opin Clin Nutr Metab Care 9: 697-703
51. Meyskens FL Jr, Kopecky KJ, Appelbaum FR et al. (1995) Effects of vitamin A on survival in patients with chronic myelogenous leukemia: a SWOG randomized trial. Leuk Res 19: 605-612
52. Mongan NP, Gudas LJ (2007) Diverse actions of retinoid receptors in cancer prevention and treatment. Differentiation
53. Mook OR, Frederiks WM, Van Noorden CJ (2004) The role of gelatinases in colorectal cancer progression and metastasis. Biochim Biophys Acta 1705: 69-89; Review
54. Murley JS, Kataoka Y, Cao D et al. (2004) Delayed radioprotection by NFkappaB-mediated induction of Sod2 (MnSOD) in SA-NH tumor cells after exposure to clinically used thiol-containing drugs. Radiat Res 162: 536-546
55. Myers C, Bonow R, Palmeri S et al. (1983) A randomized controlled trial assessing the prevention of doxorubicin cardiomyopathy by N-acetylcysteine. Semin Oncol 10: 53-55
56. Mystakidou K, Tsilika E, Parpa E et al. (2005) Assessment of anxiety and depression in advanced cancer patients and their relationship with quality of life. Qual Life Res 14: 1825-1833
57. Neuzil J, Zhao M, Ostermann G et al. (2002) Alpha-tocopheryl succinate, an agent with in vivo anti-tumour activity, induces apoptosis by causing lysosomal instability. Biochem J 362: 709-715
58. Nordsmark M, Overgaard M, Overgaard J (1996) Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck. Radiother Oncol 41: 31-39
59. Pace A, Savarese A, Picardo M et al. (2003) Neuroprotective effect of vitamin E supplementation in patients treated with cisplatin chemotherapy. J Clin Oncol 21: 927-931
60. Padayatty SJ, Riordan HD, Hewitt SM et al. (2006) Intravenously administered vitamin C as cancer therapy: three cases. CMAJ 174: 937-942
61. Pathak A, Bhutani M, Guleria R et al. (2005) Chemotherapy alone vs. chemotherapy plus high dose multiple antioxidants in patients with advanced non small cell lung cancer. J Am Coll Nutr 24: 16-21
62. Peralta EA, Viegas ML, Louis S et al. (2006) Effect of vitamin E on tamoxifen-treated breast cancer cells. Surgery 140: 607-614; discussion 614-615
63. Pinthus JH, Bryskin I, Trachtenberg J et al. (2007) Androgen induces adaptation to oxidative stress in prostate cancer: implications for treatment with radiation therapy. Neoplasia 9: 68-80
64. Posthauer ME (2006) The role of nutrition in wound care. Adv Skin Wound Care 19: 43-52
65. Prasad KN (2005) Rationale for using multiple antioxidants in protecting humans against low doses of ionizing radiation. Br J Radiol 78: 485-492
66. Prasad KN (2004) Rationale for using high-dose multiple dietary antioxidants as an adjunct to radiation therapy and chemotherapy. J Nutr 134: 3182S-3183S
67. Prasad KN, Cole WC, Kumar B, Che Prasad K (2002) Pros and cons of antioxidant use during radiation therapy. Cancer Treat Rev 28: 79-91
68. Saintot M, Mathieu-Daude H, Astre C et al. (2002) Oxidant-antioxidant status in relation to survival among breast cancer patients. Int J Cancer 97: 574-579
69. Sappino AP, Busso N, Belin D, Vassalli JD (1987) Increase of urokinase-type plasminogen activator gene expression in human lung and breast carcinomas. Cancer Res 47: 4
70. Schiff R, Reddy P, Ahotupa M et al. (2000) Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo. J Natl Cancer Inst 92: 1926-1934
71. Simone CB 2nd, Simone NL, Simone V, Simone CB (2007) Antioxidants and other nutrients do not interfere with chemotherapy or radiation therapy and can increase kill and increase survival, Part 2. Altern Ther Health Med 13: 40-47
72. Subapriya R, Kumaraguruparan R, Ramachandran CR, Nagini S (2002) Oxidant-antioxidant status in patients with oral squamous cell carcinomas at different intraoral sites. Clin Biochem 35: 489-493
73. Takada Y, Hachiya M, Park SH et al. (2002) Role of reactive oxygen species in cells overexpressing manganese superoxide dismutase: mechanism for induction of radioresistance. Mol Cancer Res 1: 137-146
74. Thews O, Lambert C, Kelleher DK et al. (2007) Impact of therapeutically induced reactive oxygen species and radical scavenging by alpha-tocopherol on tumor cell adhesion. Oncol Rep 18: 965-971
75. Tipnis SR, Blake DG, Shepherd AG, McLellan LI (1999) Overexpression of the regulatory subunit of gamma-glutamylcysteine synthetase in HeLa cells increases gamma-glutamylcysteine synthetase activity and confers drug resistance. Biochem J 337: 559-566
76. Ucuncu H, Ertekin MV, Yoruk O et al. (2006) Vitamin E and L-carnitine, separately or in combination, in the prevention of radiation-induced oral mucositis and myelosuppression: a controlled study in a rat model. J Radiat Res (Tokyo) 47: 91-102
77. Bokhorst-de van der Schuer MA van, Leeuwen PA van, Kuik DJ et al. (1999) The impact of nutritional status on the prognoses of patients with advanced head and neck cancer. Cancer 86: 519-527
78. Weijl NI, Elsendoorn TJ, Lentjes EGWM et al. (2004) Supplementation with antioxidant micronutrients and chemotherapy-induced toxicity in cancer patients treated with cisplatin-based chemotherapy: a randomised, double-blind, placebo-controlled study. Eur J Cancer 40: 1713-1723
79. Wenzel U, Nickel A, Kuntz S, Daniel H (2004) Ascorbic acid suppresses drug-induced apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions. Carcinogenesis 25: 703-712
80. Yeom CH, Jung GC, Song KJ (2007) Changes of terminal cancer patients' health-related quality of life after high dose vitamin C administration. J Korean Med Sci 22: 7-11
81. Yoon SO, Kim MM, Chung AS (2001) Inhibitory effect of selenite on invasion of HT1080 tumor cells. J Biol Chem 276: 20085-20092