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Volumn 283, Issue 1-2, 2008, Pages 1-11

The involvement of phosphatidylinositol 3-kinase in gonadotropin-releasing hormone-induced gonadotropin α- and FSHβ-subunit genes expression in clonal gonadotroph LβT2 cells

Author keywords

ERK; Gonadotroph; Gonadotropin; L T2; PI3K; PKB

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; FOLLITROPIN BETA SUBUNIT; GONADORELIN; GONADOTROPIN; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 39149102117     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2007.12.001     Document Type: Review
Times cited : (15)

References (46)
  • 1
    • 0033839153 scopus 로고    scopus 로고
    • IGF-I stimulation of luteinizing hormone secretion, IGF-binding proteins (IGFBPs) and expression of mRNAs for IGFs. IGF receptors and IGFBPs in the ovine pituitary gland
    • Adam C.L., Gadd T.S., Findlay P.A., and Wathes D.C. IGF-I stimulation of luteinizing hormone secretion, IGF-binding proteins (IGFBPs) and expression of mRNAs for IGFs. IGF receptors and IGFBPs in the ovine pituitary gland. J. Endocrinol. 166 (2000) 247-254
    • (2000) J. Endocrinol. , vol.166 , pp. 247-254
    • Adam, C.L.1    Gadd, T.S.2    Findlay, P.A.3    Wathes, D.C.4
  • 2
    • 0038071673 scopus 로고    scopus 로고
    • Differential regulation of gonadotropin subunit gene promoter activity by pulsatile gonadotropin-releasing hormone (GnRH) in perifused L beta T2 cells: role of GnRH receptor concentration
    • Bedecarrats G.Y., and Kaiser U.B. Differential regulation of gonadotropin subunit gene promoter activity by pulsatile gonadotropin-releasing hormone (GnRH) in perifused L beta T2 cells: role of GnRH receptor concentration. Endocrinology 144 (2003) 1802-1811
    • (2003) Endocrinology , vol.144 , pp. 1802-1811
    • Bedecarrats, G.Y.1    Kaiser, U.B.2
  • 3
    • 2042441750 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase, Jun N-terminal kinase, p38, and c-Src are involved in gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone follicle-stimulating hormone beta-subunit promoter
    • Bonfil D., Chuderland D., Kraus S., Shahbazian D., Friedberg I., Seger R., and Naor Z. Extracellular signal-regulated kinase, Jun N-terminal kinase, p38, and c-Src are involved in gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone follicle-stimulating hormone beta-subunit promoter. Endocrinology 145 (2004) 2228-2244
    • (2004) Endocrinology , vol.145 , pp. 2228-2244
    • Bonfil, D.1    Chuderland, D.2    Kraus, S.3    Shahbazian, D.4    Friedberg, I.5    Seger, R.6    Naor, Z.7
  • 4
    • 0032814586 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone activates the equine luteinizing hormone beta promoter through a protein kinase C/mitogen-activated protein kinase pathway
    • Call G.B., and Wolfe M.W. Gonadotropin-releasing hormone activates the equine luteinizing hormone beta promoter through a protein kinase C/mitogen-activated protein kinase pathway. Biol. Reprod. 61 (1999) 715-723
    • (1999) Biol. Reprod. , vol.61 , pp. 715-723
    • Call, G.B.1    Wolfe, M.W.2
  • 5
    • 0026667730 scopus 로고
    • AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas
    • Cheng J.Q., Godwin A.K., Bellacosa A., Taguchi T., Franke T.F., Hamilton T.C., Tsichlis P.N., and Testa J.R. AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas. Proc Natl Acad Sci USA 89 19 (1992) 9267-9271
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.19 , pp. 9267-9271
    • Cheng, J.Q.1    Godwin, A.K.2    Bellacosa, A.3    Taguchi, T.4    Franke, T.F.5    Hamilton, T.C.6    Tsichlis, P.N.7    Testa, J.R.8
  • 6
    • 18244394308 scopus 로고    scopus 로고
    • IGF-1 in the brain as a regulator of reproductive neuroendocrine function
    • Daftary S.S., and Gore A.C. IGF-1 in the brain as a regulator of reproductive neuroendocrine function. Exp. Biol. Med. (Maywood) 230 (2005) 292-306
    • (2005) Exp. Biol. Med. (Maywood) , vol.230 , pp. 292-306
    • Daftary, S.S.1    Gore, A.C.2
  • 7
    • 0041306994 scopus 로고    scopus 로고
    • Microarray analysis and identification of novel molecules involved in insulin-like growth factor-1 receptor signaling and gene expression
    • Dupont J., Dunn S.E., Barrett J.C., and LeRoith D. Microarray analysis and identification of novel molecules involved in insulin-like growth factor-1 receptor signaling and gene expression. Recent Prog. Horm. Res. 58 (2003) 325-342
    • (2003) Recent Prog. Horm. Res. , vol.58 , pp. 325-342
    • Dupont, J.1    Dunn, S.E.2    Barrett, J.C.3    LeRoith, D.4
  • 8
    • 0032053709 scopus 로고    scopus 로고
    • Mechanisms and consequences of activation of protein kinase B/Akt
    • Downward J. Mechanisms and consequences of activation of protein kinase B/Akt. Curr. Opin. Cell Biol. 10 (1998) 262-267
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 262-267
    • Downward, J.1
  • 9
    • 4544266128 scopus 로고    scopus 로고
    • IGF-I inhibits apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway in pituitary cells
    • Fernandez M., Sanchez-Franco F., Palacios N., Sanchez I., Fernandez C., and Cacicedo L. IGF-I inhibits apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway in pituitary cells. J. Mol. Endocrinol. 33 (2004) 155-163
    • (2004) J. Mol. Endocrinol. , vol.33 , pp. 155-163
    • Fernandez, M.1    Sanchez-Franco, F.2    Palacios, N.3    Sanchez, I.4    Fernandez, C.5    Cacicedo, L.6
  • 10
    • 33748535456 scopus 로고    scopus 로고
    • Mechanisms for pulsatile regulation of the gonadotropin subunit genes by GNRH1
    • Ferris H.A., and Shupnik M.A. Mechanisms for pulsatile regulation of the gonadotropin subunit genes by GNRH1. Biol. Reprod. 74 6 (2006) 993-998
    • (2006) Biol. Reprod. , vol.74 , Issue.6 , pp. 993-998
    • Ferris, H.A.1    Shupnik, M.A.2
  • 11
    • 0036721166 scopus 로고    scopus 로고
    • Regulation of human glycoprotein hormone alpha-subunit gene transcription in LbetaT2 gonadotropes by protein kinase C and extracellular signal-regulated kinase 1/2
    • Fowkes R.C., King P., and Burrin J.M. Regulation of human glycoprotein hormone alpha-subunit gene transcription in LbetaT2 gonadotropes by protein kinase C and extracellular signal-regulated kinase 1/2. Biol. Reprod. 67 (2002) 725-734
    • (2002) Biol. Reprod. , vol.67 , pp. 725-734
    • Fowkes, R.C.1    King, P.2    Burrin, J.M.3
  • 12
    • 0042721571 scopus 로고    scopus 로고
    • Gomperts B.D. (Ed), Academic Press, An Elsevier Science Imprint, San Diego, CA, USA
    • In: Gomperts B.D. (Ed). Signal Transduction (2002), Academic Press, An Elsevier Science Imprint, San Diego, CA, USA
    • (2002) Signal Transduction
  • 14
    • 0038237592 scopus 로고    scopus 로고
    • The calcium component of gonadotropin-releasing hormone-stimulated luteinizing hormone subunit gene transcription is mediated by calcium/calmodulin-dependent protein kinase type II
    • Haisenleder D.J., Ferris H.A., and Shupnik M.A. The calcium component of gonadotropin-releasing hormone-stimulated luteinizing hormone subunit gene transcription is mediated by calcium/calmodulin-dependent protein kinase type II. Endocrinology 144 (2003) 2409-2416
    • (2003) Endocrinology , vol.144 , pp. 2409-2416
    • Haisenleder, D.J.1    Ferris, H.A.2    Shupnik, M.A.3
  • 15
    • 0032893316 scopus 로고    scopus 로고
    • The protein kinase C system acts through the early growth response protein 1 to increase LHbeta gene expression in synergy with steroidogenic factor-1
    • Halvorson L.M., Kaiser U.B., and Chin W.W. The protein kinase C system acts through the early growth response protein 1 to increase LHbeta gene expression in synergy with steroidogenic factor-1. Mol. Endocrinol. 13 (1999) 106-116
    • (1999) Mol. Endocrinol. , vol.13 , pp. 106-116
    • Halvorson, L.M.1    Kaiser, U.B.2    Chin, W.W.3
  • 16
    • 0036173664 scopus 로고    scopus 로고
    • Activation of MAPK cascades by GnRH: ERK and Jun N-terminal kinase are involved in basal and GnRH-stimulated activity of the glycoprotein hormone LHbeta-subunit promoter
    • Harris D., Bonfil D., Chuderland D., Kraus S., Seger R., and Naor Z. Activation of MAPK cascades by GnRH: ERK and Jun N-terminal kinase are involved in basal and GnRH-stimulated activity of the glycoprotein hormone LHbeta-subunit promoter. Endocrinology 143 (2002) 1018-1025
    • (2002) Endocrinology , vol.143 , pp. 1018-1025
    • Harris, D.1    Bonfil, D.2    Chuderland, D.3    Kraus, S.4    Seger, R.5    Naor, Z.6
  • 17
    • 0037318494 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase and c-Src, but not Jun N-terminal kinase, are involved in basal and gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone alpha-subunit promoter
    • Harris D., Chuderland D., Bonfil D., Kraus S., Seger R., and Naor Z. Extracellular signal-regulated kinase and c-Src, but not Jun N-terminal kinase, are involved in basal and gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone alpha-subunit promoter. Endocrinology 144 (2003) 612-622
    • (2003) Endocrinology , vol.144 , pp. 612-622
    • Harris, D.1    Chuderland, D.2    Bonfil, D.3    Kraus, S.4    Seger, R.5    Naor, Z.6
  • 19
    • 0033630476 scopus 로고    scopus 로고
    • GnRH receptor and apoptotic signaling
    • Imai A., and Tamaya T. GnRH receptor and apoptotic signaling. Vitam. Horm. 59 (2000) 1-33
    • (2000) Vitam. Horm. , vol.59 , pp. 1-33
    • Imai, A.1    Tamaya, T.2
  • 20
    • 0025882091 scopus 로고
    • Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily
    • Jones P.F., Jakubowicz T., Pitossi F.J., Maurer F., and Hemmings B.A. Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 4171-4175
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 4171-4175
    • Jones, P.F.1    Jakubowicz, T.2    Pitossi, F.J.3    Maurer, F.4    Hemmings, B.A.5
  • 21
    • 0029608730 scopus 로고
    • A mechanism for the differential regulation of gonadotropin subunit gene expression by gonadotropin-releasing hormone
    • Kaiser U.B., Sabbagh E., Katzenellenbogen R.A., Conn P.M., and Chin W.W. A mechanism for the differential regulation of gonadotropin subunit gene expression by gonadotropin-releasing hormone. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 12280-12284
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 12280-12284
    • Kaiser, U.B.1    Sabbagh, E.2    Katzenellenbogen, R.A.3    Conn, P.M.4    Chin, W.W.5
  • 22
    • 11244278074 scopus 로고    scopus 로고
    • Oct-1 and nuclear factor Y bind to the SURG-1 element to direct basal and gonadotropin-releasing hormone (GnRH)-stimulated mouse GnRH receptor gene transcription
    • Kam K.Y., Jeong K.H., Norwitz E.R., Jorgensen E.M., and Kaiser U.B. Oct-1 and nuclear factor Y bind to the SURG-1 element to direct basal and gonadotropin-releasing hormone (GnRH)-stimulated mouse GnRH receptor gene transcription. Mol. Endocrinol. 19 (2005) 148-162
    • (2005) Mol. Endocrinol. , vol.19 , pp. 148-162
    • Kam, K.Y.1    Jeong, K.H.2    Norwitz, E.R.3    Jorgensen, E.M.4    Kaiser, U.B.5
  • 23
    • 0025830250 scopus 로고
    • Effect of insulin-like growth factor I on gonadotropin release from the hypothalamus-pituitary axis in vitro
    • Kanematsu T., Irahara M., Miyake T., Shitsukawa K., and Aono T. Effect of insulin-like growth factor I on gonadotropin release from the hypothalamus-pituitary axis in vitro. Acta Endocrinol. (Copenh) 125 (1991) 227-233
    • (1991) Acta Endocrinol. (Copenh) , vol.125 , pp. 227-233
    • Kanematsu, T.1    Irahara, M.2    Miyake, T.3    Shitsukawa, K.4    Aono, T.5
  • 24
    • 0027402935 scopus 로고
    • Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (alpha IR-3)
    • Kato H., Faria T.N., Stannard B., Roberts Jr. C.T., and LeRoith D. Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (alpha IR-3). J. Biol. Chem. 268 (1993) 2655-2661
    • (1993) J. Biol. Chem. , vol.268 , pp. 2655-2661
    • Kato, H.1    Faria, T.N.2    Stannard, B.3    Roberts Jr., C.T.4    LeRoith, D.5
  • 25
    • 0035044213 scopus 로고    scopus 로고
    • Clinical review 125: The insulin receptor and its cellular targets
    • Kido Y., Nakae J., and Accili D. Clinical review 125: The insulin receptor and its cellular targets. J. Clin. Endocrinol. Metab. 86 (2001) 972-979
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 972-979
    • Kido, Y.1    Nakae, J.2    Accili, D.3
  • 27
    • 0041355688 scopus 로고    scopus 로고
    • c-Src is activated by the epidermal growth factor receptor in a pathway that mediates JNK and ERK activation by gonadotropin-releasing hormone in COS7 cells
    • Kraus S., Benard O., Naor Z., and Seger R. c-Src is activated by the epidermal growth factor receptor in a pathway that mediates JNK and ERK activation by gonadotropin-releasing hormone in COS7 cells. J. Biol. Chem. 278 (2003) 32618-32630
    • (2003) J. Biol. Chem. , vol.278 , pp. 32618-32630
    • Kraus, S.1    Benard, O.2    Naor, Z.3    Seger, R.4
  • 28
    • 4143145476 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone induces apoptosis of prostate cancer cells: role of c-Jun NH2-terminal kinase, protein kinase B, and extracellular signal-regulated kinase pathways
    • Kraus S., Levy G., Hanoch T., Naor Z., and Seger R. Gonadotropin-releasing hormone induces apoptosis of prostate cancer cells: role of c-Jun NH2-terminal kinase, protein kinase B, and extracellular signal-regulated kinase pathways. Cancer Res. 64 (2004) 5736-5744
    • (2004) Cancer Res. , vol.64 , pp. 5736-5744
    • Kraus, S.1    Levy, G.2    Hanoch, T.3    Naor, Z.4    Seger, R.5
  • 29
    • 0035676783 scopus 로고    scopus 로고
    • Intracellular signaling pathways mediated by the gonadotropin-releasing hormone (GnRH) receptor
    • Kraus S., Naor Z., and Seger R. Intracellular signaling pathways mediated by the gonadotropin-releasing hormone (GnRH) receptor. Arch. Med. Res. 32 (2001) 499-509
    • (2001) Arch. Med. Res. , vol.32 , pp. 499-509
    • Kraus, S.1    Naor, Z.2    Seger, R.3
  • 30
    • 0035374998 scopus 로고    scopus 로고
    • Transient activation of Jun N-terminal kinases and protection from apoptosis by the insulin-like growth factor I receptor can be suppressed by dicumarol
    • Krause D., Lyons A., Fennelly C., and O'Connor R. Transient activation of Jun N-terminal kinases and protection from apoptosis by the insulin-like growth factor I receptor can be suppressed by dicumarol. J. Biol. Chem. 276 (2001) 19244-19252
    • (2001) J. Biol. Chem. , vol.276 , pp. 19244-19252
    • Krause, D.1    Lyons, A.2    Fennelly, C.3    O'Connor, R.4
  • 31
    • 0033190522 scopus 로고    scopus 로고
    • The insulin-like growth factor (IGF) system and gonadotropin regulation: actions and interactions
    • Lackey B.R., Gray S.L., and Henricks D.M. The insulin-like growth factor (IGF) system and gonadotropin regulation: actions and interactions. Cytokine Growth Factor Rev. 10 (1999) 201-217
    • (1999) Cytokine Growth Factor Rev. , vol.10 , pp. 201-217
    • Lackey, B.R.1    Gray, S.L.2    Henricks, D.M.3
  • 32
    • 0028957113 scopus 로고
    • Molecular and cellular aspects of the insulin-like growth factor I receptor
    • LeRoith D., Werner H., Beitner-Johnson D., and Roberts Jr. C.T. Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr. Rev. 16 (1995) 143-163
    • (1995) Endocr. Rev. , vol.16 , pp. 143-163
    • LeRoith, D.1    Werner, H.2    Beitner-Johnson, D.3    Roberts Jr., C.T.4
  • 33
    • 0038022927 scopus 로고    scopus 로고
    • Gonadotropin releasing hormone (GnRH) and estradiol (E(2)) regulation of cell cycle in gonadotrophs
    • Lewy H., Ashkenazi I.E., and Naor Z. Gonadotropin releasing hormone (GnRH) and estradiol (E(2)) regulation of cell cycle in gonadotrophs. Mol. Cell Endocrinol. 203 (2003) 25-32
    • (2003) Mol. Cell Endocrinol. , vol.203 , pp. 25-32
    • Lewy, H.1    Ashkenazi, I.E.2    Naor, Z.3
  • 34
    • 0037199927 scopus 로고    scopus 로고
    • Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor-mediated signaling in L beta T2 cells
    • Liu F., Usui I., Evans L.G., Austin D.A., Mellon P.L., Olefsky J.M., and Webster N.J. Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor-mediated signaling in L beta T2 cells. J. Biol. Chem. 277 (2002) 32099-32108
    • (2002) J. Biol. Chem. , vol.277 , pp. 32099-32108
    • Liu, F.1    Usui, I.2    Evans, L.G.3    Austin, D.A.4    Mellon, P.L.5    Olefsky, J.M.6    Webster, N.J.7
  • 35
    • 0346458794 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone receptor-mediated growth suppression of immortalized LbetaT2 gonadotrope and stable HEK293 cell lines
    • Miles L.E., Hanyaloglu A.C., Dromey J.R., Pfleger K.D., and Eidne K.A. Gonadotropin-releasing hormone receptor-mediated growth suppression of immortalized LbetaT2 gonadotrope and stable HEK293 cell lines. Endocrinology 145 (2004) 194-204
    • (2004) Endocrinology , vol.145 , pp. 194-204
    • Miles, L.E.1    Hanyaloglu, A.C.2    Dromey, J.R.3    Pfleger, K.D.4    Eidne, K.A.5
  • 36
    • 33746547892 scopus 로고    scopus 로고
    • Dependence of GnRH-induced phosphorylation of CREB and BAD on EGF receptor transactivation in GT1-7 neuronal cells
    • Neithardt A., Farshori M.P., Shah F.B., Catt K.J., and Shah B.H. Dependence of GnRH-induced phosphorylation of CREB and BAD on EGF receptor transactivation in GT1-7 neuronal cells. J. Cell. Physiol. 208 (2006) 586-593
    • (2006) J. Cell. Physiol. , vol.208 , pp. 586-593
    • Neithardt, A.1    Farshori, M.P.2    Shah, F.B.3    Catt, K.J.4    Shah, B.H.5
  • 37
    • 0031955451 scopus 로고    scopus 로고
    • Stimulatory effect of insulin-like growth factor I on proliferation of mouse pituitary cells in serum-free culture
    • Oomizu S., Takeuchi S., and Takahashi S. Stimulatory effect of insulin-like growth factor I on proliferation of mouse pituitary cells in serum-free culture. J. Endocrinol. 157 (1998) 53-62
    • (1998) J. Endocrinol. , vol.157 , pp. 53-62
    • Oomizu, S.1    Takeuchi, S.2    Takahashi, S.3
  • 39
    • 0031014651 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways
    • Parrizas M., Saltiel A.R., and LeRoith D. Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways. J. Biol. Chem. 272 (1997) 154-161
    • (1997) J. Biol. Chem. , vol.272 , pp. 154-161
    • Parrizas, M.1    Saltiel, A.R.2    LeRoith, D.3
  • 40
    • 10644258616 scopus 로고    scopus 로고
    • The luteinizing hormone-releasing hormone inhibits the anti-apoptotic activity of insulin-like growth factor-1 in pituitary alphaT3 cells by protein kinase Calpha-mediated negative regulation of Akt
    • Rose A., Froment P., Perrot V., Quon M.J., LeRoith D., and Dupont J. The luteinizing hormone-releasing hormone inhibits the anti-apoptotic activity of insulin-like growth factor-1 in pituitary alphaT3 cells by protein kinase Calpha-mediated negative regulation of Akt. J. Biol. Chem. 279 (2004) 52500-52516
    • (2004) J. Biol. Chem. , vol.279 , pp. 52500-52516
    • Rose, A.1    Froment, P.2    Perrot, V.3    Quon, M.J.4    LeRoith, D.5    Dupont, J.6
  • 41
    • 0031762011 scopus 로고    scopus 로고
    • Differential use of signal transduction pathways in the gonadotropin-releasing hormone-mediated regulation of gonadotropin subunit gene expression
    • Saunders B.D., Sabbagh E., Chin W.W., and Kaiser U.B. Differential use of signal transduction pathways in the gonadotropin-releasing hormone-mediated regulation of gonadotropin subunit gene expression. Endocrinology 139 (1998) 1835-1843
    • (1998) Endocrinology , vol.139 , pp. 1835-1843
    • Saunders, B.D.1    Sabbagh, E.2    Chin, W.W.3    Kaiser, U.B.4
  • 42
    • 28444445601 scopus 로고    scopus 로고
    • Role of EGF receptor transactivation in phosphoinositide 3-kinase-dependent activation of MAP kinase by GPCRs
    • Shah B.H., Neithardt A., Chu D.B., Shah F.B., and Catt K.J. Role of EGF receptor transactivation in phosphoinositide 3-kinase-dependent activation of MAP kinase by GPCRs. J. Cell. Physiol. 206 (2006) 47-57
    • (2006) J. Cell. Physiol. , vol.206 , pp. 47-57
    • Shah, B.H.1    Neithardt, A.2    Chu, D.B.3    Shah, F.B.4    Catt, K.J.5
  • 43
    • 0028414816 scopus 로고
    • Effect of insulin-like growth factor I on anterior pituitary function
    • Trainer P.J. Effect of insulin-like growth factor I on anterior pituitary function. Acta Paediatr. Suppl. 399 (1994) 173-175
    • (1994) Acta Paediatr. Suppl. , vol.399 , pp. 173-175
    • Trainer, P.J.1
  • 44
    • 0036721555 scopus 로고    scopus 로고
    • Different signaling pathways control acute induction versus long-term repression of LHbeta transcription by GnRH
    • Vasilyev V.V., Lawson M.A., Dipaolo D., Webster N.J., and Mellon P.L. Different signaling pathways control acute induction versus long-term repression of LHbeta transcription by GnRH. Endocrinology 143 (2002) 3414-3426
    • (2002) Endocrinology , vol.143 , pp. 3414-3426
    • Vasilyev, V.V.1    Lawson, M.A.2    Dipaolo, D.3    Webster, N.J.4    Mellon, P.L.5
  • 45
    • 0032230357 scopus 로고    scopus 로고
    • Differential gonadotropin-releasing hormone stimulation of rat luteinizing hormone subunit gene transcription by calcium influx and mitogen-activated protein kinase-signaling pathways
    • Weck J., Fallest P.C., Pitt L.K., and Shupnik M.A. Differential gonadotropin-releasing hormone stimulation of rat luteinizing hormone subunit gene transcription by calcium influx and mitogen-activated protein kinase-signaling pathways. Mol. Endocrinol. 12 (1998) 451-457
    • (1998) Mol. Endocrinol. , vol.12 , pp. 451-457
    • Weck, J.1    Fallest, P.C.2    Pitt, L.K.3    Shupnik, M.A.4


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