Proton-decoupled 31P MRS in untreated pediatric brain tumors

Magnetic Resonance in Medicine

Volumn 53, Issue 1, 2005, Pages 22-29

  Albers, Mark J ^a   Krieger, Mark D ^a,b   Gonzalez Gomez, Ignacio ^a   Gilles, Floyd H ^a   McComb, J Gordon ^a,b   Nelson Jr , Marvin D ^a   Blüml, Stefan ^a,c  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c Rudi Schulte Research Institute   (United States)

Author keywords

In vivo; Proton decoupled 31P MRS; Untreated pediatric brain tumors

Indexed keywords

BRAIN; CLASSIFICATION (OF INFORMATION); PEDIATRICS;

BRAIN TUMORS; GLYCEROPHOSPHOCHOLINE; IN-VIVO; NEUROECTODERMAL TUMORS; PEDIATRIC PATIENTS; PHOSPHOETHANOLAMINE; QUANTITATIVE COMPARISON; TUMOR CLASSIFICATION;

TUMORS;

CHOLINE; CREATINE; GLYCEROPHOSPHOETHANOLAMINE; GLYCEROPHOSPHORYLCHOLINE; PHOSPHOETHANOLAMINE; PHOSPHORYLCHOLINE; DIAGNOSTIC AGENT; ETHANOLAMINE DERIVATIVE; PHOSPHATIDYLETHANOLAMINE;

ARTICLE; BRAIN TUMOR; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DERMATOFIBROMA; EPENDYMOMA; FEMALE; HUMAN; HUMAN TISSUE; IN VIVO STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; METABOLITE; NEUROECTODERM TUMOR; PH; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PROGNOSIS; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; TUMOR CLASSIFICATION; TUMOR GROWTH; BRAIN; CASE CONTROL STUDY; CHEMISTRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

BRAIN; BRAIN NEOPLASMS; CASE-CONTROL STUDIES; CHILD; CHOLINE; CREATINE; ETHANOLAMINES; FEMALE; GLYCERYLPHOSPHORYLCHOLINE; HUMANS; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MALE; PHOSPHATIDYLETHANOLAMINES; PHOSPHORYLCHOLINE;

EID: 12144270414     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.20312     Document Type: Article

References (30)

1. Griffiths JR, Cady E, Edwards RHT, McCready VR, Wilkie DR, Wiltshaw E. 31P-NMR studies of human tumour in situ. The Lancet 1983;i:1435-1436.
2. Evanochko WT, Sakai TT, Ng TC, Krishna NR, Kim HD, Zeidler RB, Ghanta VK, Brockman RW, Schiffer LM, Braunschweiger PG, Glickson JD. NMR study of RIF-1 tumors: analysis of perchloric acid extracts and identification of 1H, 31P and 13C resonances. Biochim Biophys Acta 1984;805:104-116.
3. Podo F. Tumor phospholipid metabolism. NMR Biomed 1999;12:413-439.
4. Daly PF, Lyon RC, Faustino PJ, Cohen JS. Phospholipid metabolism in cancer cells monitored by 31P NMR spectroscopy. J Biol Chem 1987; 262:14875-14878.
5. Radda GK, Oberhaensli RD, Taylor JD. The biochemistry of human diseases as studied by 31P NMR in man and animal models. Ann NY Acad Sci 1987;508:300-308.
6. Usenius JP, Vainis P, Hernesmiemi J, Kauppinen RA. Choline-containing compounds in human astrcytomas studied by 1H NMR spectroscopy in vivo and in vitro. J Neurochem 1994;63:1538-1543.
7. Bell JD, Bhakoo KK. Metabolic changes underlying 31P MR spectral alterations in human hepatic tumours. NMR Biomed 1998;11:354-359.
8. Bhakoo KK, Williams SR, Florian CL, Land H, Nobel MD. Immortalization and transformation are associated with specific alterations in choline metabolism. Cancer Res 1996;56:4630-4635.
9. Luyten PR, Bruntink G, Sloff FM, Vermeulen JW, van der Heijden JI, den Hollander JA, Heerschap A. Broadband proton decoupling in human 31P NMR spectroscopy. NMR Biomed 1989;1:177-183.
10. Shaka AJ KJ, Frenkiel, Freeman R. An improved sequence for broad-band decoupling: WALTZ-16. J Magn Reson 1983;52:335-338.
11. FDA. Guidance for the submission of premarket notifications for magnetic resonance diagnostic devices. Operating mode limits for RF power. US Department of Health and Human Services, Food and Drug Administration 1998; http://www.fda.gov/cdrh/ode/mri340.pdf (http://www.fda.gov/cdrh/ode/mri340.pdf)
12. Bluml S, Seymour KJ, Ross BD. Developmental changes in choline- and ethanolamine-containing compounds measured with proton-decoupled (31)P MRS in vivo human brain. Magn Reson Med 1999;42: 643-654.
13. Gupta RK, Gupta P, Yushok WD, Rose ZB. Measurement of the dissociation constant of MgATP at physiological nucleotide levels by a combination of 31P NMR and optical absorbance spectroscopy. Biochem Biophys Res Commun 1983;117:210-216.
14. Kreis R, Ernst T, Ross BD. Development of the human brain: in vivo quantification of metabolite and water content with proton magnetic resonance spectroscopy. Magn Reson Med 1993;30:424-437.
15. Ernst T, Kreis R, Ross BD. Absolute quantitation of water and metabolites in the human brain. I. Compartments and water J Magn Reson 1993;102:1-8.
16. Kreis R. Quantitative localized 1H MR spectroscopy for clinical use. Prog NMR Spectrosc 1997;31:155-195.
17. Kreis R, Hofmann L, Kuhlmann B, Boesch C, Bossi E, Hueppi PS. Brain metabolite composition during early human brain development as measured by quantitative in vivo 1H magnetic resonance spectroscopy. Magn Reson Med 2002;48:949-958.
18. Jope RS, Jenden DJ. Choline and phospholipid metabolism and the synthesis of acetylcholine in rat brain. J Neurosci Res 1979;4:69-82.
19. Sabatier J, Guard V, Malet-Martino M, Ranjeva JP, Terrai C, Breil S, Delisle MB, Manelfe C, Tremoulet M, Berry I. Characterization of choline compounds with in vitro 1H magnetic resonance spectroscopy for the discrimination of primary brain tumors. Invest Radiol 1999;34: 230-235.
20. Lentner C. Geigy Scientific Tables. In: Ciba-Geigy, editor. Basel, Switzerland: Ciba-Geigy; 1981. p 222.
21. Blüml S, Philippart M, Schiffmann R, Seymour K, Ross BD. Membrane phospholipids and high-energy metabolites in childhood ataxia with CNS hypomyelination. Neurology 2003;61:648-654.
22. Negendank WG, Padavic-Shaller KA, Li CW, Murphy-Boesch J, Stoyanova R, Krigel RL, Schilder RJ, Smith MR, Brown TR. Metabolic characterization of human non-Hodgkin's lymphomas in vivo with the use of proton-decoupled phosphorus magnetic resonance spectroscopy. Cancer Res 1995;55:3286-3294.
23. Kinoshita Y, Yokota A, Koga Y. Phosphorylethanolamine content of human brain tumors. Neurol Med Chir 1994;34:803-806.
24. Kinoshita Y, Yokota A. Absolute concentrations of metabolites in human brain tumors using in vitro proton magnetic resonance spectroscopy. NMR Biomed 1997;10:2-12.
25. Gillies RJ, Barry JA, Ross BD. In vitro and in vivo 13C and 31P NMR analyses of phosphocholine metabolism in rat glioma cells. Magn Reson Med 1994;32:310-318.
26. Evelhoch JL, Keller NA, Corbett TH. Response-specific adriamycin sensitvity markers provided by in vivo 31P nuclear magnetic resonance spectroscopy in murine mammary adenocarcinomas. Cancer Res 1987; 47:3396-3401.
27. Miller BL. A review of chemical issues in 1H NMR spectroscopy: N-acetyl-L-aspartate, creatine and choline. NMR Biomed 1991;4:47-52.
28. Negendank WG. Studies of human tumors by MRS: a review. NMR Biomed 1992;5:303-324.
29. Gillies RJ, Raghunand N, Karczmar GS, Bhujwalla ZM. MRI of the tumor microenvironment. J Magn Reson Imaging 2002;16:430-450.
30. Sijens PE, Oudkerk M. 1H chemical shift imaging characterization of human brain tumor and edema. Eur Radiology 2002;12:2056-2061.