Cholinergic location of δ-opioid receptors in canine atria and SA node

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 294, Issue 2, 2008, Pages

  Deo, Shekhar H ^a   Barlow, Matthew A ^a   Gonzalez, Leticia ^a   Yoshishige, Darice ^a   Caffrey, James L ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

Opioids; Vagal function

Indexed keywords

ACETYLCHOLINE; DELTA OPIATE RECEPTOR; DIMER; MONOMER; NORADRENALIN; SYNAPSIN I; TYROSINE 3 MONOOXYGENASE; VESICULAR ACETYLCHOLINE TRANSPORTER;

ADRENERGIC SYSTEM; ANIMAL TISSUE; ARTICLE; CHOLINERGIC NERVE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DOG; GENE LOCATION; HEART ATRIUM; HEART RIGHT ATRIUM; IMMUNOFLUORESCENCE; ISCHEMIC PRECONDITIONING; MOLECULAR WEIGHT; NEUROTRANSMISSION; NONHUMAN; PARASYMPATHETIC NERVE; PRIORITY JOURNAL; REGULATORY MECHANISM; SINUS NODE; SYNAPTOSOME; TISSUE SLICE; WESTERN BLOTTING;

ACETYLCHOLINE; ANIMALS; BLOTTING, WESTERN; DOGS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLUORESCENT ANTIBODY TECHNIQUE; HEART; HEART ATRIA; IMMUNOHISTOCHEMISTRY; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MYOCARDIUM; NOREPINEPHRINE; PARASYMPATHETIC FIBERS, POSTGANGLIONIC; PARASYMPATHETIC NERVOUS SYSTEM; RECEPTORS, OPIOID, DELTA; SINOATRIAL NODE; SYMPATHETIC NERVOUS SYSTEM; SYNAPTOSOMES; VESICULAR ACETYLCHOLINE TRANSPORT PROTEINS;

EID: 39149095279     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01141.2007     Document Type: Article

References (40)

1. Arvidsson U, Dado RJ, Riedl M, Lee JH, Law PY, Loh HH, Elde R, Wessendorf MW. δ-Opioid receptor immunoreactivity: distribution in brainstem and spinal cord, and relationship to biogenic amines and enkephalin. J Neurosci 15: 1215-1235, 1995.
2. Arvidsson U, Riedl M, Elde R, Meister B. Vesicular acetylcholine transporter (VAChT) protein: a novel and unique marker for cholinergic neurons in the central and peripheral nervous systems. J Comp Neurol 378: 454-467, 1997.
3. Barlow MA, Deo S, Johnson S, Caffrey JL. Vagotonic effects of enkephalin are not mediated by sympatholytic mechanisms. Exp Biol Med (Maywood) 231: 387-395, 2006.
4. Baryla J, Greniuk G, Lakomy M. The adrenergic and cholinergic innervation of the thyroid chicken gland. Folia Morphol (Warsz) 62: 247-249, 2003.
5. Caffrey JL, Mateo Z, Napier LD, Gaugl JF, Barron BA. Intrinsic cardiac enkephalins inhibit vagal bradycardia in the dog. Am J Physiol Heart Circ Physiol 268: H848-H855, 1995.
6. Cheng Z, Powley TL. Nucleus ambiguus projections to cardiac ganglia of rat atria: an anterograde tracing study. J Comp Neurol 424: 588-606, 2000.
7. Cheng Z, Powley TL, Schwaber JS, Doyle FJ. Projections of the dorsal motor nucleus of the vagus to cardiac ganglia of rat atria: an anterograde tracing study. J Comp Neurol 410: 320-341, 1999.
8. Crain SM, Shen KF. After chronic opioid exposure sensory neurons become supersensitive to the excitatory effects of opioid agonists and antagonists as occurs after acute elevation of GM1 ganglioside. Brain Res 575: 13-24, 1992.
9. Cvejic S, Devi LA. Dimerization of the delta opioid receptor: implication for a role in receptor internalization. J Biol Chem 272: 26959-26964, 1997.
10. Farias M, Jackson K, Johnson M, Caffrey JL. Cardiac enkephalins attenuate vagal bradycardia: interactions with NOS-1-cGMP systems in canine sinoatrial node. Am J Physiol Heart Circ Physiol 285: H2001-H2012, 2003.
11. 2-opioid receptors in sinoatrial node. Am J Physiol Heart Circ Physiol 284: H1693-H1701, 2003.
12. Farias M, Jackson K, Stanfill A, Caffrey JL. Local opiate receptors in the sinoatrial node moderate vagal bradycardia. Auton Neurosci 87: 9-15, 2001.
13. Farias M, Jackson K, Yoshishige D, Caffrey JL. Bimodal δ-opioid receptors regulate vagal bradycardia in canine sinoatrial node. Am J Physiol Heart Circ Physiol 285: H1332-H1339, 2003.
14. Fields HL, Emson PC, Leigh BK, Gilbert RF, Iversen LL. Multiple opiate receptor sites on primary afferent fibres. Nature 284: 351-353, 1980.
15. Fryer RM, Pratt PF, Hsu AK, Gross GJ. Differential activation of extracellular signal regulated kinase isoforms in preconditioning and opioid-induced cardioprotection. J Pharmacol Exp Ther 296: 642-649, 2001.
16. Gaveriaux-Ruff C, Peluso J, Befort K, Simonin F, Zilliox C, Kieffer BL. Detection of opioid receptor mRNA by RT-PCR reveals alternative splicing for the delta- and kappa-opioid receptors. Brain Res Mol Brain Res 48: 298-304, 1997.
17. Gross GJ. Role of opioids in acute and delayed preconditioning. J Mol Cell Cardiol 35: 709-718, 2003.
18. Gu H, Barron BA, Gaugl JF, Caffrey JL. Dynorphin, naloxone, and overflow of norepinephrine during cardiac nerve stimulation in dogs. Am J Physiol Heart Circ Physiol 263: H153-H161, 1992.
19. Hersh LB. Degradation of enkephalins: the search for an enkephalinase. Mol Cell Biochem 47: 35-43, 1982.
20. Howells RD, Kilpatrick DL, Bailey LC, Noe M, Udenfriend S. Proenkephalin mRNA in rat heart. Proc Natl Acad Sci USA 83: 1960-1963, 1986.
21. 2-adrenergic receptor: role of the intrinsic cardiac adrenergic cell. Am J Physiol Heart Circ Physiol 293: H376-H384, 2007.
22. Jackson KE, Farias M, Stanfill AS, Caffrey JL. Transient arterial occlusion raises enkephalin in the canine sinoatrial node and improves vagal bradycardia. Auton Neurosci 94: 84-92, 2001.
23. James TN. Structure and function of the sinus node, AV node and his bundle of the human heart. II. Function. Prog Cardiovasc Dis 45: 327-360, 2003.
24. Lewis RV. Enkephalin biosynthesis in the adrenal medulla. Adv Biochem Psychopharmacol 33: 167-174, 1982.
25. Lonergan T, Goodchild AK, Christie MJ, Pilowsky PM. Presynaptic delta opioid receptors differentially modulate rhythm and pattern generation in the ventral respiratory group of the rat. Neuroscience 121: 959-973, 2003.
26. Paradis P, Dumont M, Belichard P, Rouleau JL, Lemaire S, Brakier-Gingras L. Increased preproenkephalin A gene expression in the rat heart after induction of a myocardial infarction. Biochem Cell Biol 70: 593-598, 1992.
27. Patel HH, Head BP, Petersen HN, Niesman IR, Huang D, Gross GJ, Insel PA, Roth DM. Protection of adult rat cardiac myocytes from ischemic cell death: role of caveolar microdomains and δ-opioid receptors. Am J Physiol Heart Circ Physiol 291: H344-H350, 2006.
28. Portoghese PS. From models to molecules: opioid receptor dimers, bivalent ligands, and selective opioid receptor probes. J Med Chem 44: 2259-2269, 2001.
29. Rabgaoui N, Slaoui-Hasnaoui A, Torreilles J. Boomerang effect between [Met]-enkephalin derivatives and human polymorphonuclear leukocytes. Free Radic Biol Med 14: 519-529, 1993.
30. 3H]D-aspartate release from rat frontal cortex in vitro. Neuropharmacology 49: 59-72, 2005.
31. Schultz JE, Hsu AK, Gross GJ. Ischemic preconditioning in the intact rat heart is mediated by delta1- but not mu- or kappa-opioid receptors. Circulation 97: 1282-1289, 1998.
32. Schultz JJ, Hsu AK, Gross GJ. Ischemic preconditioning and morphine-induced cardioprotection involve the delta (δ)-opioid receptor in the intact rat heart. J Mol Cell Cardiol 29: 2187-2195, 1997.
33. Stanfill AA, Jackson K, Farias M, Barlow M, Deo S, Johnson S, Caffrey JL. Leucine-enkephalin interrupts sympathetically mediated tachycardia prejunctionally in the canine sinoatrial node. Exp Biol Med (Maywood) 228: 898-906, 2003.
34. Surratt CK, Adams WR. G protein-coupled receptor structural motifs: relevance to the opioid receptors. Curr Top Med Chem 5: 315-324, 2005.
35. Takasaki Y, Wolff RA, Chien GL, van Winkle DM. Met5-enkephalin protects isolated adult rabbit cardiomyocytes via δ-opioid receptors. Am J Physiol Heart Circ Physiol 277: H2442-H2450, 1999.
36. Urbani A, Bongiorno L, Marini M, Zona C, Roda LG. Hydrolysis of leucine enkephalin and its association to the K562(S) erythroleukaemic cell line. Immunopharmacology 27: 119-130, 1994.
37. Varga EV, Li X, Stropova D, Zalewska T, Landsman RS, Knapp RJ, Malatynska E, Kawai K, Mizusura A, Nagase H, Calderon SN, Rice K, Hruby VJ, Roeske WR, Yamamura HI. The third extracellular loop of the human delta-opioid receptor determines the selectivity of delta-opioid agonists. Mol Pharmacol 50: 1619-1624, 1996.
38. Whittaker VP, Michaelson IA, Kirkland RJ. The separation of synaptic vesicles from nerve-ending particles ("synaptosomes"). Biochem J 90: 293-303, 1964.
39. Younes A, Pepe S, Barron BA, Spurgeon HA, Lakatta EG, Caffrey JL. Cardiac synthesis, processing, and coronary release of enkephalin-related peptides. Am J Physiol Heart Circ Physiol 279: H1989-H1998, 2000.
40. Zhang X, Bao L, Arvidsson U, Elde R, Hokfelt T. Localization and regulation of the delta-opioid receptor in dorsal root ganglia and spinal cord of the rat and monkey: evidence for association with the membrane of large dense-core vesicles. Neuroscience 82: 1225-1242, 1998.