Up-regulation of Murid herpesvirus 4 ORF50 by hypoxia: Possible implication for virus reactivation from latency

Virus Research

Volumn 132, Issue 1-2, 2008, Pages 257-262

  Polcicova, Katarina ^a   Hrabovska, Zuzana ^b   Mistrikova, Jela ^b   Tomaskova, Jana ^a   Pastorek, Jaromir ^a   Pastorekova, Silvia ^a   Kopacek, Juraj ^a  

^a INSTITUTE OF VIROLOGY   (Slovakia)

^b Physics and Informatics   (Slovakia)

Author keywords

Hypoxia; Latent infection; Murid herpesvirus 4; ORF50

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 2ALPHA; LUCIFERASE;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC TRANSFECTION; HERPES VIRUS; HYPOXIA; IMMUNOFLUORESCENCE; MURID HERPESVIRUS 4; NONHUMAN; OPEN READING FRAME; ORF50 GENE; OXYGEN CONCENTRATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; VIRUS GENE; VIRUS LATENCY; VIRUS REACTIVATION;

ANIMALS; ANTIGENS, VIRAL; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL HYPOXIA; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, VIRAL; GENES, REPORTER; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; OPEN READING FRAMES; OXYGEN; PROMOTER REGIONS (GENETICS); RHADINOVIRUS; TIME FACTORS; TRANSCRIPTION FACTORS; UP-REGULATION; VIRUS ACTIVATION; VIRUS LATENCY;

MURID HERPESVIRUS 4; MUS;

EID: 39149093009     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virusres.2007.12.004     Document Type: Article

References (41)

1. Alain T., Hirasawa K., Pon K.J., Nishikawa S.G., Urbanski S.J., Auer Y., Luider J., Martin A., Johnston R.N., Janowska-Wieczorek A., Lee P.W., and Kossakowska A.E. Reovirus therapy of lymphoid malignancies. Blood 100 12 (2002) 4146-4153
2. Andreansky S.S., He B., Gillespie G.Y., Soroceanu L., Markert J., Chou J., Roizman B., and Whitley R.J. The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors. Proc. Natl. Acad. Sci. U.S.A. 93 21 (1996) 11313-11318
3. Bais C., Santomasso B., Coso O., Arvanitakis L., Raaka E.G., Gutkind J.S., Asch A.S., Cesarman E., Gershengorn M.C., and Mesri E.A. G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator. Nature 391 6662 (1998) 86-89
4. Balachandran S., Porosnicu M., and Barber G.N. Oncolytic activity of vesicular stomatitis virus is effective against tumors exhibiting aberrant p53, Ras, or myc function and involves the induction of apoptosis. J. Virol. 75 7 (2001) 3474-3479
5. Binley K., Askham Z., Martin L., Spearman H., Day D., Kingsman S., and Naylor S. Hypoxia-mediated tumour targeting. Gene Ther. 10 7 (2003) 540-549
6. Blaskovic D., Stancekova M., Svobodova J., and Mistrikova J. Isolation of five strains of herpesviruses from two species of free living small rodents. Acta Virol. 24 6 (1980) 468
7. Cai Q., Lan K., Verma S.C., Si H., Lin D., and Robertson E.S. Kaposi's sarcoma-associated herpesvirus latent protein LANA interacts with HIF-1 alpha to upregulate RTA expression during hypoxia: latency control under low oxygen conditions. J. Virol. 80 16 (2006) 7965-7975
8. Davis D.A., Rinderknecht A.S., Zoeteweij J.P., Aoki Y., Read-Connole E.L., Tosato G., Blauvelt A., and Yarchoan R. Hypoxia induces lytic replication of Kaposi sarcoma-associated herpesvirus. Blood 97 10 (2001) 3244-3250
9. Flamme I., Frohlich T., von Reutern M., Kappel A., Damert A., and Risau W. HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 alpha and developmentally expressed in blood vessels. Mech. Dev. 63 1 (1997) 51-60
10. Giatromanolaki A., and Harris A.L. Tumour hypoxia, hypoxia signaling pathways and hypoxia inducible factor expression in human cancer. Anticancer Res. 21 6B (2001) 4317-4324
11. Hair J.R., Lyons P.A., Smith K.G., and Efstathiou S. Control of Rta expression critically determines transcription of viral and cellular genes following gammaherpesvirus infection. J. Gen. Virol. 88 Pt 6 (2007) 1689-1697
12. Haque M., Davis D.A., Wang V., Widmer I., and Yarchoan R. Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) contains hypoxia response elements: relevance to lytic induction by hypoxia. J. Virol. 77 12 (2003) 6761-6768
13. Hardcastle J., Kurozumi K., Chiocca E.A., and Kaur B. Oncolytic viruses driven by tumor-specific promoters. Curr. Cancer Drug Targets 7 2 (2007) 181-189
14. Hsu J.L., and Glaser S.L. Epstein-barr virus-associated malignancies: epidemiologic patterns and etiologic implications. Crit. Rev. Oncol. Hematol. 34 1 (2000) 27-53
15. Jiang J.H., Wang N., Li A., Liao W.T., Pan Z.G., Mai S.J., Li D.J., Zeng M.S., Wen J.M., and Zeng Y.X. Hypoxia can contribute to the induction of the Epstein-Barr virus (EBV) lytic cycle. J. Clin. Virol. 37 2 (2006) 98-103
16. Kondo S., Seo S.Y., Yoshizaki T., Wakisaka N., Furukawa M., Joab I., Jang K.L., and Pagano J.S. EBV latent membrane protein 1 up-regulates hypoxia-inducible factor 1alpha through Siah1-mediated down-regulation of prolyl hydroxylases 1 and 3 in nasopharyngeal epithelial cells. Cancer Res. 66 20 (2006) 9870-9877
17. Kozuch O., Reichel M., Lesso J., Remenova A., Labuda M., Lysy J., and Mistrikova J. Further isolation of murine herpesviruses from small mammals in southwestern Slovakia. Acta Virol. 37 1 (1993) 101-105
18. Liu S., Pavlova I.V., Virgin H.W.t., and Speck S.H. Characterization of gammaherpesvirus 68 gene 50 transcription. J. Virol. 74 4 (2000) 2029-2037
19. Liu J., Harada H., Ogura M., Shibata T., and Hiraoka M. Adenovirus-mediated hypoxia-targeting cytosine deaminase gene therapy enhances radiotherapy in tumour xenografts. Br. J. Cancer 96 12 (2007) 1871-1878
20. Lofstedt T., Fredlund E., Holmquist-Mengelbier L., Pietras A., Ovenberger M., Poellinger L., and Pahlman S. Hypoxia inducible factor-2alpha in cancer. Cell Cycle 6 8 (2007) 919-926
21. Lopez-Ocejo O., Viloria-Petit A., Bequet-Romero M., Mukhopadhyay D., Rak J., and Kerbel R.S. Oncogenes and tumor angiogenesis: the HPV-16 E6 oncoprotein activates the vascular endothelial growth factor (VEGF) gene promoter in a p53 independent manner. Oncogene 19 40 (2000) 4611-4620
22. Masood R., Cai J., Zheng T., Smith D.L., Naidu Y., and Gill P.S. Vascular endothelial growth factor/vascular permeability factor is an autocrine growth factor for AIDS-Kaposi sarcoma. Proc. Natl. Acad. Sci. U.S.A. 94 3 (1997) 979-984
23. Maxwell P.H., Wiesener M.S., Chang G.W., Clifford S.C., Vaux E.C., Cockman M.E., Wykoff C.C., Pugh C.W., Maher E.R., and Ratcliffe P.J. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399 6733 (1999) 271-275
24. Mistrikova J., Blaskovicova J., Pappova M., and Hricova M. Establishment and characterization of a tumor cell line derived from a mouse infected with murine gammaherpesvirus 78. Acta Virol. 50 4 (2006) 223-227
25. Rajcani J., and Kudelova M. Murine herpesvirus pathogenesis: a model for the analysis of molecular mechanisms of human gamma herpesvirus infections. Acta Microbiol. Immunol. Hung. 52 1 (2005) 41-71
26. Semenza G.L. Expression of hypoxia-inducible factor 1: mechanisms and consequences. Biochem. Pharmacol. 59 1 (2000) 47-53
27. Semenza G.L., Jiang B.H., Leung S.W., Passantino R., Concordet J.P., Maire P., and Giallongo A. Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J. Biol. Chem. 271 51 (1996) 32529-32537
28. Simas J.P., and Efstathiou S. Murine gammaherpesvirus 68: a model for the study of gammaherpesvirus pathogenesis. Trends Microbiol. 6 7 (1998) 276-282
29. Sinkovics J.G., and Horvath J.C. Newcastle disease virus (NDV): brief history of its oncolytic strains. J. Clin. Virol. 16 1 (2000) 1-15
30. Sunil-Chandra N.P., Efstathiou S., Arno J., and Nash A.A. Virological and pathological features of mice infected with murine gamma-herpesvirus 68. J. Gen. Virol. 73 Pt 9 (1992) 2347-2356
31. Sunil-Chandra N.P., Efstathiou S., and Nash A.A. Murine gammaherpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo. J. Gen. Virol. 73 Pt 12 (1992) 3275-3279
32. Sunil-Chandra N.P., Arno J., Fazakerley J., and Nash A.A. Lymphoproliferative disease in mice infected with murine gammaherpesvirus 68. Am. J. Pathol. 145 4 (1994) 818-826
33. Svobodova J., Stancekova M., Blaskovic D., Mistrikova J., Lesso J., Russ G., and Masarova P. Antigenic relatedness of alphaherpesviruses isolated from free-living rodents. Acta Virol. 26 6 (1982) 438-443
34. Tang X., Zhang Q., Nishitani J., Brown J., Shi S., and Le A.D. Overexpression of human papillomavirus type 16 oncoproteins enhances hypoxia-inducible factor 1 alpha protein accumulation and vascular endothelial growth factor expression in human cervical carcinoma cells. Clin. Cancer Res. 13 9 (2007) 2568-2576
35. Viejo-Borbolla A., and Schulz T.F. Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8): key aspects of epidemiology and pathogenesis. AIDS Rev. 5 4 (2003) 222-229
36. Virgin H.W.t., Latreille P., Wamsley P., Hallsworth K., Weck K.E., Dal Canto A.J., and Speck S.H. Complete sequence and genomic analysis of murine gammaherpesvirus 68. J. Virol. 71 8 (1997) 5894-5904
37. Wang G.L., and Semenza G.L. Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia. J. Biol. Chem. 268 29 (1993) 21513-21518
38. Weck K.E., Barkon M.L., Yoo L.I., Speck S.H., and Virgin H.I. Mature B cells are required for acute splenic infection, but not for establishment of latency, by murine gammaherpesvirus 68. J. Virol. 70 10 (1996) 6775-6780
39. Wiesener M.S., Turley H., Allen W.E., Willam C., Eckardt K.U., Talks K.L., Wood S.M., Gatter K.C., Harris A.L., Pugh C.W., Ratcliffe P.J., and Maxwell P.H. Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha. Blood 92 7 (1998) 2260-2268
40. Yoo Y.G., Oh S.H., Park E.S., Cho H., Lee N., Park H., Kim D.K., Yu D.Y., Seong J.K., and Lee M.O. Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway. J. Biol. Chem. 278 40 (2003) 39076-39084
41. Yoo Y.G., Cho S., Park S., and Lee M.O. The carboxy-terminus of the hepatitis B virus X protein is necessary and sufficient for the activation of hypoxia-inducible factor-1alpha. FEBS Lett. 577 1-2 (2004) 121-126