Myosin light-chain kinase regulates endothelial calcium entry and endothelium-dependent vasodilation

FASEB Journal

Volumn 15, Issue 2, 2001, Pages 282-284

  Watanabe, Hiroshi ^a   Tran, Quang Kim ^a   Takeuchi, Kazuhiko ^a   Fukao, Mitsuhiro ^b   Liu, Ming Y ^b   Kanno, Morio ^b   Hayashi, Toshio ^c   Iguchi, Akihisa ^c   Seto, Minoru ^d   Ohashi, Kyoichi ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d ASAHI CHEMICAL INDUSTRY CO   (Japan)

Author keywords

Calcium; Endothelium derived; Hyperpolarizing factor; Nitric oxide

Indexed keywords

ACETYLCHOLINE; ANTISENSE OLIGONUCLEOTIDE; BRADYKININ; CALCIUM; CALYCULIN A; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; ENDOTHELIUM DERIVED RELAXING FACTOR; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN KINASE; NITRIC OXIDE; THAPSIGARGIN; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENETIC TRANSFECTION; HYPERPOLARIZATION; MALE; MESENTERIC ARTERY; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; SMOOTH MUSCLE CELL; SMOOTH MUSCLE FIBER MEMBRANE; VASODILATATION; ANIMAL; CALCIUM SIGNALING; DRUG EFFECT; GENETICS; IN VITRO STUDY; METABOLISM; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

ACETYLCHOLINE; ANIMALS; BRADYKININ; CALCIUM; CALCIUM SIGNALING; ENDOTHELIUM, VASCULAR; MUSCLE, SMOOTH, VASCULAR; MYOSIN-LIGHT-CHAIN KINASE; RECOMBINANT PROTEINS; THAPSIGARGIN; TRANSFECTION; VASODILATION;

EID: 0035257363     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.00-0587fje     Document Type: Article

References (30)

1. Adelstein, R.S., Eisenberg, E. (1980) Regulation and kinetics of the actin-myosin-ATP interaction. Annu. Rev. Biochem. 49, 921-956
2. Kamm, K.E., Stull, J.T. (1985) The function of myosin and myosin light chain kinase phosphorylation smooth muscle. Annu. Rev. Pharmacol. Toxicol. 25, 593-620
3. Saitoh, M., Ishikawa, T., Matsushima, S., Naka, M., and Hidaka, H. (1987) Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase. J. Biol. Chem. 262, 7796-7801
4. Nakanishi, S., Kakita, S., Takahashi, I., Kawahara, K., Tsukuda, E., Sano, T., Yamada, K., Yoshida, M., Kase, H., Matsuda, Y., Hashimoto, Y., and Nonomura, Y. (1992) Wortmannin, a microbial product inhibitor of myosin light chain kinase. J. Biol. Chem. 267, 2157-2163
5. Garcia, J.G.N., Lazar, V., Gilbert-McClain, L.I., Gallagher, P.J., and Verin, A.D. (1997) Myosin light chain kinase in endothelium: molecular cloning and regulation. Am. J. Respir. Cell Mol. Biol. 16, 489-494
6. Wysolmerski, R.B., and Lagunoff, D. (1990) Involvement of myosin light-chain kinase in endothelial cell retraction. Proc. Natl. Acad. Sci. USA 87, 16-20
7. Watanabe, H., Takahashi, R., Zhang, X.X., Goto, Y., Hayashi, H., Ando, J., Isshiki, M., Seto, M., Hidaka, H., Niki, I., and Ohno, R. (1998) An essential role of myosin light-chain kinase in the regulation of agonist- and fluid flow-stimulated Ca2++ influx in endothelial cells. FASEB J. 12, 341-348
8. Curry, F. E. (1992) Modulation of venular microvessel permeability by calcium influx into endothelial cells. FASEB J. 6, 2456-2466
9. Palmer, R.M., Ashton, D.S., and Moncada, S. (1998) Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 333, 664-666
10. Ignarro, L.J. (1989) Endothelium-derived nitric oxide: actions and properties. FASEB J. 3, 31-36
11. Furchgott, R. F., and Vanhoutte, P. M. (1989) Endotheliumderived relaxing and contracting factors. FASEB J. 3, 2007-2018
12. Chen, G.F., and Suzuki, H. (1990) Calcium dependency of the endothelium-dependent hyperpolarization in smooth muscle cells of the rabbit carotid artery. J. Physiol. (Lond) 421, 521-534
13. Fukao, M., Hattori, Y., Kanno, M., Sakuma, I., and Kitabatake, A. (1997) Sources of Ca2++ in relation to generation of acetylcholineinduced endothelium-dependent hyperpolarization in rat mesenteric artery. Br. J. Pharmacol. 120, 1328-1334
14. Lückhoff, A., Pohl, U., Mulsch, A., and Busse, R. (1988) Differential role of extra- and intracellular calcium in the release of EDRF and prostacyclin from cultured endothelial cells. Br. J. Pharmacol. 95, 189-196
15. Hallam, T.J., Pearson, J.D., and Needham, A. (1988) Thrombinstimulated elevation of human endothelial-cell cytoplasmic free calcium concentration causes prostacyclin production. Biochem. J. 251, 243-249
16. Piper, H.M., Spahr, R., Mertens, S., Krützfeldt, A., and Watanabe, H. Microvascular endothelial cells from heart. In Cell Culture Techniques in Heart and Vessel Research; Piper, H.M. Ed. Springer- Verlag Berlin Heidelberg: Germany, 1990; pp. 158-177
17. Byron, K.L., Babnigg, G., and Villereal, M.L. (1992) Bradykinininduced Ca2++ entry, release, and refilling of intracellular Ca2++ stores. J. Biol. Chem. 267, 108-118
18. Berridge, M.J. (1993) Inositol trisphosphate and calcium signaling. Nature 361, 315-25
19. Putney, J.W., and Bird, G.J. (1993) The inositol phosphatecalcium signaling system in nonexcitable cells. Endocrin. Rev. 14, 610-631
20. Thastrup, O., Cullen, P.J., Drobak, B.K., Hanley, M.R., and Dawson, A.P. (1990) Thapsigargin, a tumor promoter, discharges intracellular Ca2++ stores by specific inhibition of the endoplasmic reticulum Ca2++-ATPase. Proc. Natl. Acad. Sci. USA. 87, 2466-2470
21. Chartier, L., Rankin, L.L., Allen, R.E., Kato, Y., Fusetani, N., Karaki, H., Watabe, S., and Hartshorne, D.J. (1991) Calyculin-A increases the level of protein phosphorylation and changes the shape of 3T3 fibroblasts. Cell Motil. Cytoskeleton 18, 26-40
22. Rameh, L.E., Rhee, S.G., Spokes, K., Kazlauskas, A., Cantley, L.C., and Cantley, L.G. (1998) Phosphoinositide 3-kinase regulates phospholipase C gamma-mediated calcium signaling. J. Biol. Chem. 273, 23750-23757
23. Gerland, C.J., Plane, F., Kemp, B.K., and Cocks, T.M. (1995) Endothelium-dependent hyperpolarization: a role in the control of the vascular tone. Trends Pharmacol. Sci. 16, 23-30
24. Adam, D.J., Barakeh, J., Laskey, R., and van Breemen, C. (1989) Ion channels and regulation of intracellular calcium in vascular endothelial cells. FASEB J. 3, 2389-2400
25. Randriamampita, C., Tsien, R.Y. (1993) Emptying of intracellular Ca2++ stores releases a novel small messenger that stimulates Ca2++ influx. Nature 364, 809-814
26. Lin, S., Fagan, K.A., Li, K.X., Shaul, P.W., Cooper, D.M., and Rodman, D.M. (2000) Sustained endothelial nitric-oxide synthase activation requires capacitative Ca2++ entry. J. Biol. Chem. 275, 17979-17985
27. Edwards, G., Dora, K.A., Gardener, M.J., Garland, C.J., and Weston, A.H. (1998) K+ is an endothelium-derived hyperpolarizing factor in rat arteries. Nature 396, 269-272
28. Bolz, S.S., Fisslthaler, B., Pieperhoff, S., Wit, C.D., Fleming, I., Busse, R., and Pohl, U. (2000) Antisense oligonucleotides against cytochrome P450 2C8 attenuate EDHF-mediated Ca2++ changes and dilation in isolated resistance arteries. FASEB J. 14, 255-260
29. Nathanson, N.M. (1987) Molecular properties of the muscarinic acetylcholine receptor. Annu. Rev. Neurosci. 10, 195-236
30. Fukao, M., Hattori, Y., Kanno, M., Sakuma, I., and Kitabatake, A. (1995) Thapsigargin- and cyclopiazonic acid-induced endotheliumdependent hyperpolarization in rat mesenteric artery. Br. J. Pharmacol. 115, 987-992