-
1
-
-
1842484230
-
The development of the antitumour benzothiazole prodrug, Phortress, as a clinical candidate
-
Bradshaw TD and Westwell AD: The development of the antitumour benzothiazole prodrug, Phortress, as a clinical candidate. Curr Med Chem 11: 1009-1021, 2004.
-
(2004)
Curr Med Chem
, vol.11
, pp. 1009-1021
-
-
Bradshaw, T.D.1
Westwell, A.D.2
-
2
-
-
0037463319
-
DNA damage and cell cycle arrest induced by 2-(4-amino-3-methylphenyl)-5- fluoro-benzothiazole (5F 203, NSC 703786) is attenuated in aryl hydrocarbon receptor deficient MCF-7 cells
-
Trapani V, Patel V, Leong CO, et al: DNA damage and cell cycle arrest induced by 2-(4-amino-3-methylphenyl)-5-fluoro-benzothiazole (5F 203, NSC 703786) is attenuated in aryl hydrocarbon receptor deficient MCF-7 cells. Br J Cancer 88: 599-605, 2003.
-
(2003)
Br J Cancer
, vol.88
, pp. 599-605
-
-
Trapani, V.1
Patel, V.2
Leong, C.O.3
-
3
-
-
0036463840
-
Preclinical evaluation of amino acid prodrugs of novel antitumor 2-(4-amino-3-methylphenyl)benzothiazoles
-
Bradshaw TD, Bibby MC, Double JA, et al: Preclinical evaluation of amino acid prodrugs of novel antitumor 2-(4-amino-3-methylphenyl)benzothiazoles. Mol Cancer Ther 1: 239-246, 2002.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 239-246
-
-
Bradshaw, T.D.1
Bibby, M.C.2
Double, J.A.3
-
4
-
-
9444263203
-
Fluorinated 2-(4-amino-3-methylphenyl)benzothiazoles induce CYP1A1 expression, become metabolized, and bind to macromolecules in sensitive human cancer cells
-
Brantley E, Trapani V, Alley MC, et al: Fluorinated 2-(4-amino-3- methylphenyl)benzothiazoles induce CYP1A1 expression, become metabolized, and bind to macromolecules in sensitive human cancer cells. Drug Metab Dispos 32: 1392-1401, 2004.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 1392-1401
-
-
Brantley, E.1
Trapani, V.2
Alley, M.C.3
-
5
-
-
0037428819
-
Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo
-
Leong CO, Gaskell M, Martin EA, et al: Antitumour 2-(4-aminophenyl) benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo. Br J Cancer 88: 470-477, 2003.
-
(2003)
Br J Cancer
, vol.88
, pp. 470-477
-
-
Leong, C.O.1
Gaskell, M.2
Martin, E.A.3
-
6
-
-
12344263872
-
In vitro, in vivo, and in silico analyses of the antitumor activity of 2-(4-amino-3-methylphenyl)-5-fluoro-benzothiazoles
-
Leong CO, Suggitt M, Swaine DJ, Bibby MC, Stevens MF and Bradshaw TD: In vitro, in vivo, and in silico analyses of the antitumor activity of 2-(4-amino-3-methylphenyl)-5-fluoro-benzothiazoles. Mol Cancer Ther 3: 1565-1575, 2004.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 1565-1575
-
-
Leong, C.O.1
Suggitt, M.2
Swaine, D.J.3
Bibby, M.C.4
Stevens, M.F.5
Bradshaw, T.D.6
-
7
-
-
0015822275
-
Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria
-
Jaffe EA, Nachman RL, Becker CG and Minick CR: Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 52: 2745-2756, 1973.
-
(1973)
J Clin Invest
, vol.52
, pp. 2745-2756
-
-
Jaffe, E.A.1
Nachman, R.L.2
Becker, C.G.3
Minick, C.R.4
-
8
-
-
14844293843
-
Cytotoxic and antiangiogenic activity of AW464 (NSC 706704), a novel thioredoxin inhibitor: An in vitro study
-
Mukherjee A, Westwell AD, Bradshaw TD, Stevens MF, Carmichael J and Martin SG: Cytotoxic and antiangiogenic activity of AW464 (NSC 706704), a novel thioredoxin inhibitor: an in vitro study. Br J Cancer 92: 350-358, 2005.
-
(2005)
Br J Cancer
, vol.92
, pp. 350-358
-
-
Mukherjee, A.1
Westwell, A.D.2
Bradshaw, T.D.3
Stevens, M.F.4
Carmichael, J.5
Martin, S.G.6
-
9
-
-
0023130372
-
Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing
-
Carmichael J, De Graff WG, Gazdar AF, Minna JD and Mitchell JB: Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res 47: 936-942, 1987. (Pubitemid 17027905)
-
(1987)
Cancer Research
, vol.47
, Issue.4
, pp. 936-942
-
-
Carmichael, J.1
DeGraff, W.G.2
Gazdar, A.F.3
-
10
-
-
0023158779
-
Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of radiosensitivity
-
Carmichael J, De Graff WG, Gazdar AF, Minna JD and Mitchell JB: Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of radiosensitivity. Cancer Res 47: 943-946, 1987. (Pubitemid 17027906)
-
(1987)
Cancer Research
, vol.47
, Issue.4
, pp. 943-946
-
-
Carmichael, J.1
DeGraff, W.G.2
Gazdar, A.F.3
-
11
-
-
0031020572
-
Paclitaxel-induced apoptosis in MCF-7 breast-cancer cells
-
Saunders DE, Lawrence WD, Christensen C, Wappler NL, Ruan H and Deppe G: Paclitaxel-induced apoptosis in MCF-7 breast-cancer cells. Int J Cancer 70: 214-220, 1997.
-
(1997)
Int J Cancer
, vol.70
, pp. 214-220
-
-
Saunders, D.E.1
Lawrence, W.D.2
Christensen, C.3
Wappler, N.L.4
Ruan, H.5
Deppe, G.6
-
12
-
-
0027517847
-
Cytotoxic studies of paclitaxel (Taxol) in human tumour cell lines
-
Liebmann JE, Cook JA, Lipschultz C, Teague D, Fisher J and Mitchell JB: Cytotoxic studies of paclitaxel (Taxol) in human tumour cell lines. Br J Cancer 68: 1104-1109, 1993.
-
(1993)
Br J Cancer
, vol.68
, pp. 1104-1109
-
-
Liebmann, J.E.1
Cook, J.A.2
Lipschultz, C.3
Teague, D.4
Fisher, J.5
Mitchell, J.B.6
-
14
-
-
0034798718
-
Targeting angiogenic processes by combination rofecoxib and ionizing radiation
-
Dicker AP, Williams TL and Grant DS: Targeting angiogenic processes by combination rofecoxib and ionizing radiation. Am J Clin Oncol 24: 438-442, 2001.
-
(2001)
Am J Clin Oncol
, vol.24
, pp. 438-442
-
-
Dicker, A.P.1
Williams, T.L.2
Grant, D.S.3
-
15
-
-
0942294665
-
In vitro Matrigel angiogenesis assays
-
Murray JC (ed.) Humana Press, Totowa, NJ
-
Ponce ML: In vitro Matrigel angiogenesis assays. In: Angiogenesis Protocols. Murray JC (ed.) Humana Press, Totowa, NJ, pp205-212, 2000.
-
(2000)
Angiogenesis Protocols
, pp. 205-212
-
-
Ponce, M.L.1
-
16
-
-
0030634825
-
Differential effects of taxol on two human cancer cell lines
-
Banerjee S, Fallis AG and Brown DL: Differential effects of taxol on two human cancer cell lines. Oncol Res 9: 237-248, 1997. (Pubitemid 127825976)
-
(1997)
Oncology Research
, vol.9
, Issue.5
, pp. 237-248
-
-
Banerjee, S.1
Fallis, A.G.2
Brown, D.L.3
-
17
-
-
0030809343
-
Paclitaxel and N-Methylformamide: In vitro interactions in human colon cancer cell line
-
Valenti AM, Niero A, Monti G, Marangolo F and Marangolo M: Paclitaxel and N-methylformamide: in vitro interactions in human colon cancer cell line. Anticancer Res 17A: 2491-2497, 1997. (Pubitemid 27352642)
-
(1997)
Anticancer Research
, vol.17
, Issue.4 A
, pp. 2491-2497
-
-
Valenti, A.M.1
Niero, A.2
Monti, G.3
Marangolo, F.4
Marangolo, M.5
-
18
-
-
0029802685
-
The microtubule-affecting drug paclitaxel has antiangiogenic activity
-
Belotti D, Vergani V, Drudis T, et al: The microtubule-affecting drug paclitaxel has antiangiogenic activity. Clin Cancer Res 2: 1843-1849, 1996.
-
(1996)
Clin Cancer Res
, vol.2
, pp. 1843-1849
-
-
Belotti, D.1
Vergani, V.2
Drudis, T.3
-
19
-
-
0031842757
-
Drug resistance and P-glycoprotein expression in endothelial cells of newly formed capillaries induced by tumors
-
Iwahana M, Utoguchi N, Mayumi T, Goryo M and Okada K: Drug resistance and P-glycoprotein expression in endothelial cells of newly formed capillaries induced by tumors. Anticancer Res 18C: 2977-2980, 1998. (Pubitemid 28388801)
-
(1998)
Anticancer Research
, vol.18
, Issue.4 C
, pp. 2977-2980
-
-
Iwahana, M.1
Utoguchi, N.2
Mayumi, T.3
Goryo, M.4
Okada, K.5
-
20
-
-
0025204095
-
Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth
-
Ingber D, Fujita T, Kishimoto S, et al: Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth. Nature 348: 555-557, 1990. (Pubitemid 120015110)
-
(1990)
Nature
, vol.348
, Issue.6301
, pp. 555-557
-
-
Ingber, D.1
Fujita, T.2
Kishimoto, S.3
Sudo, K.4
Kanamaru, T.5
Brem, H.6
Folkman, J.7
-
21
-
-
4344616516
-
Quantitative angiogenesis assays in vivo - A review
-
DOI 10.1023/B:AGEN.0000037338.51851.d1
-
Hasan J, Shnyder SD, Bibby M, Double JA, Bicknel R and Jayson GC: Quantitative angiogenesis assays in vivo - a review. Angiogenesis 7: 1-16, 2004. (Pubitemid 39127766)
-
(2004)
Angiogenesis
, vol.7
, Issue.1
, pp. 1-16
-
-
Hasan, J.1
Shnyder, S.D.2
Bibby, M.3
Double, J.A.4
Bicknel, R.5
Jayson, G.C.6
-
22
-
-
0028359292
-
AGM-1470 inhibits the growth of human glioblastoma cells in vitro and in vivo
-
Takamiya Y, Brem H, Ojeifo J, Mineta T and Martuza RL: AGM-1470 inhibits the growth of human glioblastoma cells in vitro and in vivo. Neurosurgery 34: 869-875, 1994. (Pubitemid 24130067)
-
(1994)
Neurosurgery
, vol.34
, Issue.5
, pp. 869-875
-
-
Takamiya, Y.1
Brem, H.2
Ojeifo, J.3
Mineta, T.4
Martuza, R.L.5
Kornblith, P.L.6
Sawaya, R.7
-
23
-
-
78650283647
-
Preclinical aspects of drug discovery and development
-
3rd edition. Lippincott, Williams and Wilikins, Philadelphia, PA, lwwoncology.com
-
Chabner BA and Longo DL: Preclinical aspects of drug discovery and development. In: Cancer Chemotherapy and Biotherapy. 3rd edition. Lippincott, Williams and Wilikins, Philadelphia, PA, lwwoncology.com, 2002.
-
(2002)
Cancer Chemotherapy and Biotherapy
-
-
Chabner, B.A.1
Longo, D.L.2
-
24
-
-
0034694214
-
Evaluation of benzo(a) pyrene-induced DNA damage in human endothelial cells using alkaline single cell gel electrophoresis
-
Annas A, Brittebo E and Hellman B: Evaluation of benzo(a) pyrene-induced DNA damage in human endothelial cells using alkaline single cell gel electrophoresis. Mutat Res 471: 145-155, 2000.
-
(2000)
Mutat Res
, vol.471
, pp. 145-155
-
-
Annas, A.1
Brittebo, E.2
Hellman, B.3
-
25
-
-
0028953763
-
Induction of cytochrome P4501A1 by aryl hydrocarbon receptor agonists in porcine aorta endothelial cells in culture and cytochrome P4501A1 activity in intact cells
-
Stegeman JJ, Hahn ME, Weisbrod R, et al: Induction of cytochrome P4501A1 by aryl hydrocarbon receptor agonists in porcine aorta endothelial cells in culture and cytochrome P4501A1 activity in intact cells. Mol Pharmacol 47: 296-306, 1995.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 296-306
-
-
Stegeman, J.J.1
Hahn, M.E.2
Weisbrod, R.3
-
26
-
-
17744417304
-
Glucocorticoid potentiation of cytochrome P4501A1 induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin in porcine and human endothelial cells in culture
-
Celander M, Weisbrod R and Stegeman JJ: Glucocorticoid potentiation of cytochrome P4501A1 induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin in porcine and human endothelial cells in culture. Biochem Biophys Res Commun 232: 749-753, 1997.
-
(1997)
Biochem Biophys Res Commun
, vol.232
, pp. 749-753
-
-
Celander, M.1
Weisbrod, R.2
Stegeman, J.J.3
-
27
-
-
0034665390
-
Role of Cyp1A1 in modulation of antitumor properties of the novel agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203, NSC 674495) in human breast cancer cells
-
Chua MS, Kashiyama E, Bradshaw TD, Stinson SF, Brantley E, Sausville EA and Stevens MF: Role of Cyp1A1 in modulation of antitumor properties of the novel agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203, NSC 674495) in human breast cancer cells. Cancer Res 60: 5196-5203, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 5196-5203
-
-
Chua, M.S.1
Kashiyama, E.2
Bradshaw, T.D.3
Stinson, S.F.4
Brantley, E.5
Sausville, E.A.6
Stevens, M.F.7
-
28
-
-
0036140930
-
Aryl hydrocarbon receptor mediates sensitivity of MCF-7 breast cancer cells to antitumor agent 2-(4-Amino-3-methylphenyl) benzothiazole
-
DOI 10.1124/mol.61.1.13
-
Loaiza-Perez AI, Trapani V, Hose C, Singh SS, Trepel JB, Stevens MF and Bradshaw TD: Aryl hydrocarbon receptor mediates sensitivity of MCF-7 breast cancer cells to antitumor agent 2-(4-amino-3-methylphenyl) benzothiazole. Mol Pharmacol 61: 13-19, 2002. (Pubitemid 34049507)
-
(2002)
Molecular Pharmacology
, vol.61
, Issue.1
, pp. 13-19
-
-
Loaiza-Perez, A.I.1
Trapani, V.2
Hose, C.3
Singh, S.S.4
Trepel, J.B.5
Stevens, M.F.G.6
Bradshaw, T.D.7
Sausville, E.A.8
-
29
-
-
0034049570
-
Mechanisms of acquired resistance to 2-(4-aminophenyl)benzothiazole (CJM 126, NSC 34445)
-
Bradshaw TD, Chua MS, Orr S, Matthews CS and Stevens MF: Mechanisms of acquired resistance to 2-(4-aminophenyl)benzothiazole (CJM 126, NSC 34445). Br J Cancer 83: 270-277, 2000. (Pubitemid 30411729)
-
(2000)
British Journal of Cancer
, vol.83
, Issue.2
, pp. 270-277
-
-
Bradshaw, T.D.1
Chua, M.-S.2
Orr, S.3
Matthews, C.S.4
Stevens, M.F.G.5
-
30
-
-
4544294382
-
The experimental antitumor agents phortress and doxorubicin are equiactive against human-derived breast carcinoma xenograft models
-
DOI 10.1023/B:BREA.0000041586.64371.88
-
Fichtner I, Monks A, Hose C, Stevens MF and Bradshaw TD: The experimental antitumor agents Phortress and doxorubicin are equiactive against human-derived breast carcinoma xenograft models. Breast Cancer Res Treat 87: 97-107, 2004. (Pubitemid 39237787)
-
(2004)
Breast Cancer Research and Treatment
, vol.87
, Issue.1
, pp. 97-107
-
-
Fichtner, I.1
Monks, A.2
Hose, C.3
Stevens, M.F.G.4
Bradshaw, T.D.5
|