메뉴 건너뛰기




Volumn 12, Issue 3, 2008, Pages 385-394

The effects of ibuprofen and the neurokinin-1 receptor antagonist GR205171A on Fos expression in the ferret trigeminal nucleus following tooth pulp stimulation

Author keywords

Fos; Ibuprofen; Neurokinin 1 receptor; Tooth pulp; Trigeminal nucleus

Indexed keywords

IBUPROFEN; NEUROKININ 1 RECEPTOR ANTAGONIST; PROTEIN FOS; VOFOPITANT;

EID: 39049167740     PISSN: 10903801     EISSN: 15322149     Source Type: Journal    
DOI: 10.1016/j.ejpain.2007.07.010     Document Type: Article
Times cited : (5)

References (60)
  • 1
    • 0030798999 scopus 로고    scopus 로고
    • Inflammation increases the distribution of dorsal horn neurons that internalize the neurokinin-1 receptor in response to noxious and non-noxious stimulation
    • Abbadie C., Trafton J., Liu H., Mantyh P.W., and Basbaum A.I. Inflammation increases the distribution of dorsal horn neurons that internalize the neurokinin-1 receptor in response to noxious and non-noxious stimulation. J Neurosci 17 (1997) 8049-8060
    • (1997) J Neurosci , vol.17 , pp. 8049-8060
    • Abbadie, C.1    Trafton, J.2    Liu, H.3    Mantyh, P.W.4    Basbaum, A.I.5
  • 2
    • 0030877822 scopus 로고    scopus 로고
    • Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: imaging peptide action in vivo
    • Allen B.J., Rogers S.D., Ghilardi J.R., Menning P.M., Kuskowski M.A., Basbaum A.I., et al. Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: imaging peptide action in vivo. J Neurosci 17 (1997) 5921-5927
    • (1997) J Neurosci , vol.17 , pp. 5921-5927
    • Allen, B.J.1    Rogers, S.D.2    Ghilardi, J.R.3    Menning, P.M.4    Kuskowski, M.A.5    Basbaum, A.I.6
  • 3
    • 0037393782 scopus 로고    scopus 로고
    • Review of the analgesic efficacy of ibuprofen
    • Beaver W.T. Review of the analgesic efficacy of ibuprofen. Int J Clin Pract Suppl (2003) 13-17
    • (2003) Int J Clin Pract Suppl , pp. 13-17
    • Beaver, W.T.1
  • 4
    • 0030597962 scopus 로고    scopus 로고
    • Up-regulation of cyclooxygenase-2 mRNA in the rat spinal cord following peripheral inflammation
    • Beiche F., Scheuerer S., Brune K., Geisslinger G., and Goppelt-Struebe M. Up-regulation of cyclooxygenase-2 mRNA in the rat spinal cord following peripheral inflammation. FEBS Lett 390 (1996) 165-169
    • (1996) FEBS Lett , vol.390 , pp. 165-169
    • Beiche, F.1    Scheuerer, S.2    Brune, K.3    Geisslinger, G.4    Goppelt-Struebe, M.5
  • 5
    • 0033008936 scopus 로고    scopus 로고
    • Involvement of substance P in the anti-inflammatory effects of the peripherally selective kappa-opioid asimadoline and the NK1 antagonist GR205171
    • Binder W., Scott C., and Walker J.S. Involvement of substance P in the anti-inflammatory effects of the peripherally selective kappa-opioid asimadoline and the NK1 antagonist GR205171. Eur J Neurosci 11 (1999) 2065-2072
    • (1999) Eur J Neurosci , vol.11 , pp. 2065-2072
    • Binder, W.1    Scott, C.2    Walker, J.S.3
  • 6
    • 0028999428 scopus 로고
    • Morphological characterization of substance P receptor-immunoreactive neurons in the rat spinal cord and trigeminal nucleus caudalis
    • Brown J.L., Liu H., Maggio J.E., Vigna S.R., Mantyh P.W., and Basbaum A.I. Morphological characterization of substance P receptor-immunoreactive neurons in the rat spinal cord and trigeminal nucleus caudalis. J Comp Neurol 356 (1995) 327-344
    • (1995) J Comp Neurol , vol.356 , pp. 327-344
    • Brown, J.L.1    Liu, H.2    Maggio, J.E.3    Vigna, S.R.4    Mantyh, P.W.5    Basbaum, A.I.6
  • 7
    • 0020701547 scopus 로고
    • Thresholds to electrical stimulation of nerves in cat canine tooth-pulp with A beta-, A delta- and C-fibre conduction velocities
    • Cadden S.W., Lisney S.J., and Matthews B. Thresholds to electrical stimulation of nerves in cat canine tooth-pulp with A beta-, A delta- and C-fibre conduction velocities. Brain Res 261 (1983) 31-41
    • (1983) Brain Res , vol.261 , pp. 31-41
    • Cadden, S.W.1    Lisney, S.J.2    Matthews, B.3
  • 8
    • 4243393312 scopus 로고    scopus 로고
    • Validation of the dual channel weight average as an instrument of the measurement of clinically relevant pain
    • Clayton N.M., Oakley I., Thompson S.A.W., Sargent B., and Bountra C. Validation of the dual channel weight average as an instrument of the measurement of clinically relevant pain. Br J Pharmacol 120 Proc Suppl (1997) 219P
    • (1997) Br J Pharmacol , vol.120 , Issue.Proc SUPPL
    • Clayton, N.M.1    Oakley, I.2    Thompson, S.A.W.3    Sargent, B.4    Bountra, C.5
  • 9
    • 29144498985 scopus 로고    scopus 로고
    • Fos, nociception and the dorsal horn
    • Coggeshall R.E. Fos, nociception and the dorsal horn. Prog Neurobiol 77 (2005) 299-352
    • (2005) Prog Neurobiol , vol.77 , pp. 299-352
    • Coggeshall, R.E.1
  • 10
    • 0032401787 scopus 로고    scopus 로고
    • Reversal of behavioural and electrophysiological correlates of experimental peripheral neuropathy by the NK1 receptor antagonist GR205171 in rats
    • Cumberbatch M.J., Carlson E., Wyatt A., Boyce S., Hill R.G., and Rupniak N.M. Reversal of behavioural and electrophysiological correlates of experimental peripheral neuropathy by the NK1 receptor antagonist GR205171 in rats. Neuropharmacology 37 (1998) 1535-1543
    • (1998) Neuropharmacology , vol.37 , pp. 1535-1543
    • Cumberbatch, M.J.1    Carlson, E.2    Wyatt, A.3    Boyce, S.4    Hill, R.G.5    Rupniak, N.M.6
  • 11
    • 0037391891 scopus 로고    scopus 로고
    • Relative efficacy of selective COX-2 inhibitors compared with over-the-counter ibuprofen
    • Dionne R. Relative efficacy of selective COX-2 inhibitors compared with over-the-counter ibuprofen. Int J Clin Pract Suppl (2003) 18-22
    • (2003) Int J Clin Pract Suppl , pp. 18-22
    • Dionne, R.1
  • 13
    • 0023950602 scopus 로고
    • Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the cat
    • Duggan A.W., Hendry I.A., Morton C.R., Hutchison W.D., and Zhao Z.Q. Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the cat. Brain Res 451 (1988) 261-273
    • (1988) Brain Res , vol.451 , pp. 261-273
    • Duggan, A.W.1    Hendry, I.A.2    Morton, C.R.3    Hutchison, W.D.4    Zhao, Z.Q.5
  • 14
    • 0032541192 scopus 로고    scopus 로고
    • The tachykinin NK1 receptor antagonist GR205171 prevents vagal stimulation-induced retching but not neuronal transmission from emetic vagal afferents to solitary nucleus neurons in dogs
    • Fukuda H., Koga T., Furukawa N., Nakamura E., and Shiroshita Y. The tachykinin NK1 receptor antagonist GR205171 prevents vagal stimulation-induced retching but not neuronal transmission from emetic vagal afferents to solitary nucleus neurons in dogs. Brain Res 802 (1998) 221-231
    • (1998) Brain Res , vol.802 , pp. 221-231
    • Fukuda, H.1    Koga, T.2    Furukawa, N.3    Nakamura, E.4    Shiroshita, Y.5
  • 15
    • 0032589003 scopus 로고    scopus 로고
    • The tachykinin NK1 receptor antagonist GR205171 abolishes the retching activity of neurons comprising the central pattern generator for vomiting in dogs
    • Fukuda H., Koga T., Furukawa N., Nakamura E., and Shiroshita Y. The tachykinin NK1 receptor antagonist GR205171 abolishes the retching activity of neurons comprising the central pattern generator for vomiting in dogs. Neurosci Res 33 (1999) 25-32
    • (1999) Neurosci Res , vol.33 , pp. 25-32
    • Fukuda, H.1    Koga, T.2    Furukawa, N.3    Nakamura, E.4    Shiroshita, Y.5
  • 16
    • 0030603866 scopus 로고    scopus 로고
    • GR205171: a novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity
    • Gardner C.J., Armour D.R., Beattie D.T., Gale J.D., Hawcock A.B., Kilpatrick G.J., et al. GR205171: a novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity. Regul Pept 65 (1996) 45-53
    • (1996) Regul Pept , vol.65 , pp. 45-53
    • Gardner, C.J.1    Armour, D.R.2    Beattie, D.T.3    Gale, J.D.4    Hawcock, A.B.5    Kilpatrick, G.J.6
  • 17
    • 0026637909 scopus 로고
    • Enhanced release of immunoreactive CGRP and substance P from spinal dorsal horn slices occurs during carrageenan inflammation
    • Garry M.G., and Hargreaves K.M. Enhanced release of immunoreactive CGRP and substance P from spinal dorsal horn slices occurs during carrageenan inflammation. Brain Res 582 (1992) 139-142
    • (1992) Brain Res , vol.582 , pp. 139-142
    • Garry, M.G.1    Hargreaves, K.M.2
  • 18
    • 0031841875 scopus 로고    scopus 로고
    • Substance P blockade with the potent and centrally acting antagonist GR205171 does not effect central trigeminal activity with superior sagittal sinus stimulation
    • Goadsby P.J., Hoskin K.L., and Knight Y.E. Substance P blockade with the potent and centrally acting antagonist GR205171 does not effect central trigeminal activity with superior sagittal sinus stimulation. Neuroscience 86 (1998) 337-343
    • (1998) Neuroscience , vol.86 , pp. 337-343
    • Goadsby, P.J.1    Hoskin, K.L.2    Knight, Y.E.3
  • 22
    • 39049155216 scopus 로고    scopus 로고
    • Gooch CL. The emetic response to cisplatin in the ferret: immunohistochemical and gastrointestinal studies. PhD thesis. University of Sheffield, UK; 2003.
    • Gooch CL. The emetic response to cisplatin in the ferret: immunohistochemical and gastrointestinal studies. PhD thesis. University of Sheffield, UK; 2003.
  • 24
    • 0034214841 scopus 로고    scopus 로고
    • NK1 (substance P) receptor antagonists - why are they not analgesic in humans?
    • Hill R. NK1 (substance P) receptor antagonists - why are they not analgesic in humans?. Trends Pharmacol Sci 21 (2000) 244-246
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 244-246
    • Hill, R.1
  • 25
    • 33646349493 scopus 로고    scopus 로고
    • The use of COX-2 inhibitors for acute dental pain: a second look
    • Huber M.A., and Terezhalmy G.T. The use of COX-2 inhibitors for acute dental pain: a second look. J Am Dent Assoc 137 (2006) 480-487
    • (2006) J Am Dent Assoc , vol.137 , pp. 480-487
    • Huber, M.A.1    Terezhalmy, G.T.2
  • 26
    • 0037817385 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is induced in the endothelial cells throughout the central nervous system during carrageenan-induced hind paw inflammation; its possible role in hyperalgesia
    • Ibuki T., Matsumura K., Yamazaki Y., Nozaki T., Tanaka Y., and Kobayashi S. Cyclooxygenase-2 is induced in the endothelial cells throughout the central nervous system during carrageenan-induced hind paw inflammation; its possible role in hyperalgesia. J Neurochem 86 (2003) 318-328
    • (2003) J Neurochem , vol.86 , pp. 318-328
    • Ibuki, T.1    Matsumura, K.2    Yamazaki, Y.3    Nozaki, T.4    Tanaka, Y.5    Kobayashi, S.6
  • 27
    • 33751440393 scopus 로고    scopus 로고
    • Synergistic interactions between the dual serotonergic, noradrenergic reuptake inhibitor duloxetine and the non-steroidal anti-inflammatory drug ibuprofen in inflammatory pain in rodents
    • Jones C.K., Peters S.C., and Shannon H.E. Synergistic interactions between the dual serotonergic, noradrenergic reuptake inhibitor duloxetine and the non-steroidal anti-inflammatory drug ibuprofen in inflammatory pain in rodents. Eur J Pain 11 (2007) 208-215
    • (2007) Eur J Pain , vol.11 , pp. 208-215
    • Jones, C.K.1    Peters, S.C.2    Shannon, H.E.3
  • 28
    • 0026440476 scopus 로고
    • Excitation of cutaneous afferent nerve endings in vitro by a combination of inflammatory mediators and conditioning effect of substance P
    • Kessler W., Kirchhoff C., Reeh P.W., and Handwerker H.O. Excitation of cutaneous afferent nerve endings in vitro by a combination of inflammatory mediators and conditioning effect of substance P. Exp Brain Res 91 (1992) 467-476
    • (1992) Exp Brain Res , vol.91 , pp. 467-476
    • Kessler, W.1    Kirchhoff, C.2    Reeh, P.W.3    Handwerker, H.O.4
  • 30
    • 0027225257 scopus 로고
    • Peptides and the primary afferent nociceptor
    • Levine J.D., Fields H.L., and Basbaum A.I. Peptides and the primary afferent nociceptor. J Neurosci 13 (1993) 2273-2286
    • (1993) J Neurosci , vol.13 , pp. 2273-2286
    • Levine, J.D.1    Fields, H.L.2    Basbaum, A.I.3
  • 31
    • 0034082781 scopus 로고    scopus 로고
    • The relationship between neurokinin-1 receptor and substance P in the medullary dorsal horn: a light and electron microscopic immunohistochemical study in the rat
    • Li J.L., Wang D., Kaneko T., Shigemoto R., Nomura S., and Mizuno N. The relationship between neurokinin-1 receptor and substance P in the medullary dorsal horn: a light and electron microscopic immunohistochemical study in the rat. Neurosci Res 36 (2000) 327-334
    • (2000) Neurosci Res , vol.36 , pp. 327-334
    • Li, J.L.1    Wang, D.2    Kaneko, T.3    Shigemoto, R.4    Nomura, S.5    Mizuno, N.6
  • 32
    • 0029012284 scopus 로고
    • The types of neuron in spinal dorsal horn which possess neurokinin-1 receptors
    • Littlewood N.K., Todd A.J., Spike R.C., Watt C., and Shehab S.A. The types of neuron in spinal dorsal horn which possess neurokinin-1 receptors. Neuroscience 66 (1995) 597-608
    • (1995) Neuroscience , vol.66 , pp. 597-608
    • Littlewood, N.K.1    Todd, A.J.2    Spike, R.C.3    Watt, C.4    Shehab, S.A.5
  • 34
    • 0000822075 scopus 로고    scopus 로고
    • Neurokinin antagonists as potential agents for use in pain management
    • Ma O.-P., and Hill R.G. Neurokinin antagonists as potential agents for use in pain management. Curr Opin Invest Drug 1 (1999) 65-71
    • (1999) Curr Opin Invest Drug , vol.1 , pp. 65-71
    • Ma, O.-P.1    Hill, R.G.2
  • 35
    • 0028999848 scopus 로고
    • Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation
    • Mantyh P.W., DeMaster E., Malhotra A., Ghilardi J.R., Rogers S.D., Mantyh C.R., et al. Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation. Science 268 (1995) 1629-1632
    • (1995) Science , vol.268 , pp. 1629-1632
    • Mantyh, P.W.1    DeMaster, E.2    Malhotra, A.3    Ghilardi, J.R.4    Rogers, S.D.5    Mantyh, C.R.6
  • 36
    • 32944464344 scopus 로고    scopus 로고
    • Synergism between paracetamol and nonsteroidal anti-inflammatory drugs in experimental acute pain
    • Miranda H.F., Puig M.M., Prieto J.C., and Pinardi G. Synergism between paracetamol and nonsteroidal anti-inflammatory drugs in experimental acute pain. Pain 121 (2006) 22-28
    • (2006) Pain , vol.121 , pp. 22-28
    • Miranda, H.F.1    Puig, M.M.2    Prieto, J.C.3    Pinardi, G.4
  • 38
    • 13044305848 scopus 로고    scopus 로고
    • Transmission of chronic nociception by spinal neurons expressing the substance P receptor
    • Nichols M.L., Allen B.J., Rogers S.D., Ghilardi J.R., Honore P., Luger N.M., et al. Transmission of chronic nociception by spinal neurons expressing the substance P receptor. Science 286 (1999) 1558-1561
    • (1999) Science , vol.286 , pp. 1558-1561
    • Nichols, M.L.1    Allen, B.J.2    Rogers, S.D.3    Ghilardi, J.R.4    Honore, P.5    Luger, N.M.6
  • 39
    • 39049123040 scopus 로고    scopus 로고
    • Correlation of substance P and calcitonin gene-related peptide with trigeminal Fos expression
    • Oakden E.L., and Boissonade F.M. Correlation of substance P and calcitonin gene-related peptide with trigeminal Fos expression. J Dent Res 76 (1997) 1074
    • (1997) J Dent Res , vol.76 , pp. 1074
    • Oakden, E.L.1    Boissonade, F.M.2
  • 40
    • 0031961326 scopus 로고    scopus 로고
    • Fos expression in the ferret trigeminal nuclear complex following tooth pulp stimulation
    • Oakden E.L., and Boissonade F.M. Fos expression in the ferret trigeminal nuclear complex following tooth pulp stimulation. Neuroscience 84 (1998) 1197-1208
    • (1998) Neuroscience , vol.84 , pp. 1197-1208
    • Oakden, E.L.1    Boissonade, F.M.2
  • 41
    • 0001297080 scopus 로고
    • On the anatomical and functional organization of the spinal trigeminal nucleus
    • Olszewski J. On the anatomical and functional organization of the spinal trigeminal nucleus. J Comp Neurol 92 (1950) 401-413
    • (1950) J Comp Neurol , vol.92 , pp. 401-413
    • Olszewski, J.1
  • 42
    • 33646891527 scopus 로고    scopus 로고
    • Brain uptake of nonsteroidal anti-inflammatory drugs: ibuprofen, flurbiprofen, and indomethacin
    • Parepally J.M., Mandula H., and Smith Q.R. Brain uptake of nonsteroidal anti-inflammatory drugs: ibuprofen, flurbiprofen, and indomethacin. Pharm Res 23 (2006) 873-881
    • (2006) Pharm Res , vol.23 , pp. 873-881
    • Parepally, J.M.1    Mandula, H.2    Smith, Q.R.3
  • 43
    • 0030935008 scopus 로고    scopus 로고
    • The non-peptide NK-1 receptor antagonist LY303870 inhibits neurogenic dural inflammation in guinea pigs
    • Phebus L.A., Johnson K.W., Stengel P.W., Lobb K.L., Nixon J.A., and Hipskind P.A. The non-peptide NK-1 receptor antagonist LY303870 inhibits neurogenic dural inflammation in guinea pigs. Life Sci 60 (1997) 1553-1561
    • (1997) Life Sci , vol.60 , pp. 1553-1561
    • Phebus, L.A.1    Johnson, K.W.2    Stengel, P.W.3    Lobb, K.L.4    Nixon, J.A.5    Hipskind, P.A.6
  • 44
    • 0037395424 scopus 로고    scopus 로고
    • Discovery, mechanisms of action and safety of ibuprofen
    • Rainsford K.D. Discovery, mechanisms of action and safety of ibuprofen. Int J Clin Pract Suppl (2003) 3-8
    • (2003) Int J Clin Pract Suppl , pp. 3-8
    • Rainsford, K.D.1
  • 45
    • 0002462931 scopus 로고    scopus 로고
    • Comparison of the neurokinin-1 antagonist L-754,030, to placebo, acetaminophen and ibuprofen in the dental pain model
    • Reinhardt R.R., Laub J.B., Frieke J.R., Polis A.B., and Gertz B.J. Comparison of the neurokinin-1 antagonist L-754,030, to placebo, acetaminophen and ibuprofen in the dental pain model. Clin Pharmacol Ther 63 (1998) 168
    • (1998) Clin Pharmacol Ther , vol.63 , pp. 168
    • Reinhardt, R.R.1    Laub, J.B.2    Frieke, J.R.3    Polis, A.B.4    Gertz, B.J.5
  • 46
    • 0030031674 scopus 로고    scopus 로고
    • An isobolographic analysis of the effects of N-methyl-d-aspartate and NK1 tachykinin receptor antagonists on inflammatory hyperalgesia in the rat
    • Ren K., Iadarola M.J., and Dubner R. An isobolographic analysis of the effects of N-methyl-d-aspartate and NK1 tachykinin receptor antagonists on inflammatory hyperalgesia in the rat. Br J Pharmacol 117 (1996) 196-202
    • (1996) Br J Pharmacol , vol.117 , pp. 196-202
    • Ren, K.1    Iadarola, M.J.2    Dubner, R.3
  • 47
    • 0034571251 scopus 로고    scopus 로고
    • Substance P expression in human tooth pulp in relation to caries and pain experience
    • Rodd H.D., and Boissonade F.M. Substance P expression in human tooth pulp in relation to caries and pain experience. Eur J Oral Sci 108 (2000) 467-474
    • (2000) Eur J Oral Sci , vol.108 , pp. 467-474
    • Rodd, H.D.1    Boissonade, F.M.2
  • 48
    • 0030246919 scopus 로고    scopus 로고
    • Enantioselective inhibition of the formalin paw late phase by the NK1 receptor antagonist L-733,060 in gerbils
    • Rupniak N.M., Carlson E., Boyce S., Webb J.K., and Hill R.G. Enantioselective inhibition of the formalin paw late phase by the NK1 receptor antagonist L-733,060 in gerbils. Pain 67 (1996) 189-195
    • (1996) Pain , vol.67 , pp. 189-195
    • Rupniak, N.M.1    Carlson, E.2    Boyce, S.3    Webb, J.K.4    Hill, R.G.5
  • 49
    • 0036145242 scopus 로고    scopus 로고
    • Tooth extraction-induced internalization of the substance P receptor in trigeminal nucleus and spinal cord neurons: imaging the neurochemistry of dental pain
    • Sabino M.A., Honore P., Rogers S.D., Mach D.B., Luger N.M., and Mantyh P.W. Tooth extraction-induced internalization of the substance P receptor in trigeminal nucleus and spinal cord neurons: imaging the neurochemistry of dental pain. Pain 95 (2002) 175-186
    • (2002) Pain , vol.95 , pp. 175-186
    • Sabino, M.A.1    Honore, P.2    Rogers, S.D.3    Mach, D.B.4    Luger, N.M.5    Mantyh, P.W.6
  • 50
    • 0035932121 scopus 로고    scopus 로고
    • Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity
    • Samad T.A., Moore K.A., Sapirstein A., Billet S., Allchorne A., Poole S., et al. Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature 410 (2001) 471-475
    • (2001) Nature , vol.410 , pp. 471-475
    • Samad, T.A.1    Moore, K.A.2    Sapirstein, A.3    Billet, S.4    Allchorne, A.5    Poole, S.6
  • 51
    • 0141738787 scopus 로고    scopus 로고
    • Cyclo-oxygenase-2 contributes to central sensitization in rats with peripheral inflammation
    • Seybold V.S., Jia Y.P., and Abrahams L.G. Cyclo-oxygenase-2 contributes to central sensitization in rats with peripheral inflammation. Pain 105 (2003) 47-55
    • (2003) Pain , vol.105 , pp. 47-55
    • Seybold, V.S.1    Jia, Y.P.2    Abrahams, L.G.3
  • 52
    • 0027339837 scopus 로고
    • The non-peptide neurokinin1 receptor antagonist, RP 67580, blocks neurogenic plasma extravasation in the dura mater of rats
    • Shepheard S.L., Williamson D.J., Hill R.G., and Hargreaves R.J. The non-peptide neurokinin1 receptor antagonist, RP 67580, blocks neurogenic plasma extravasation in the dura mater of rats. Br J Pharmacol 108 (1993) 11-12
    • (1993) Br J Pharmacol , vol.108 , pp. 11-12
    • Shepheard, S.L.1    Williamson, D.J.2    Hill, R.G.3    Hargreaves, R.J.4
  • 53
    • 0028941078 scopus 로고
    • Comparison of the effects of sumatriptan and the NK1 antagonist CP-99,994 on plasma extravasation in Dura mater and c-fos mRNA expression in trigeminal nucleus caudalis of rats
    • Shepheard S.L., Williamson D.J., Williams J., Hill R.G., and Hargreaves R.J. Comparison of the effects of sumatriptan and the NK1 antagonist CP-99,994 on plasma extravasation in Dura mater and c-fos mRNA expression in trigeminal nucleus caudalis of rats. Neuropharmacology 34 (1995) 255-261
    • (1995) Neuropharmacology , vol.34 , pp. 255-261
    • Shepheard, S.L.1    Williamson, D.J.2    Williams, J.3    Hill, R.G.4    Hargreaves, R.J.5
  • 54
    • 33745428781 scopus 로고    scopus 로고
    • The NK1-receptor antagonist TKA731 in painful diabetic neuropathy: a randomised, controlled trial
    • Sindrup S.H., Graf A., and Sfikas N. The NK1-receptor antagonist TKA731 in painful diabetic neuropathy: a randomised, controlled trial. Eur J Pain 10 (2006) 567-571
    • (2006) Eur J Pain , vol.10 , pp. 567-571
    • Sindrup, S.H.1    Graf, A.2    Sfikas, N.3
  • 55
    • 21844470257 scopus 로고    scopus 로고
    • Activation of NK1 receptor of trigeminal root ganglion via substance P paracrine mechanism contributes to the mechanical allodynia in the temporomandibular joint inflammation in rats
    • Takeda M., Tanimoto T., Nasu M., Ikeda M., Kadoi J., and Matsumoto S. Activation of NK1 receptor of trigeminal root ganglion via substance P paracrine mechanism contributes to the mechanical allodynia in the temporomandibular joint inflammation in rats. Pain 116 (2005) 375-385
    • (2005) Pain , vol.116 , pp. 375-385
    • Takeda, M.1    Tanimoto, T.2    Nasu, M.3    Ikeda, M.4    Kadoi, J.5    Matsumoto, S.6
  • 56
    • 0030246892 scopus 로고    scopus 로고
    • The spinal contribution of substance P to the generation and maintenance of inflammatory hyperalgesia in the rat
    • Traub R.J. The spinal contribution of substance P to the generation and maintenance of inflammatory hyperalgesia in the rat. Pain 67 (1996) 151-161
    • (1996) Pain , vol.67 , pp. 151-161
    • Traub, R.J.1
  • 57
    • 0034406976 scopus 로고    scopus 로고
    • NK1 receptor antagonists - are they really without effect in the pain clinic?
    • author reply 465
    • Urban L.A., and Fox A.J. NK1 receptor antagonists - are they really without effect in the pain clinic?. Trends Pharmacol Sci 21 (2000) 462-464 author reply 465
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 462-464
    • Urban, L.A.1    Fox, A.J.2
  • 59
    • 0028904320 scopus 로고
    • Noxious peripheral stimulation produces antinociception mediated via substance P and opioid mechanisms in the rat tail-flick test
    • Yashpal K., Pitcher G.M., and Henry J.L. Noxious peripheral stimulation produces antinociception mediated via substance P and opioid mechanisms in the rat tail-flick test. Brain Res 674 (1995) 97-103
    • (1995) Brain Res , vol.674 , pp. 97-103
    • Yashpal, K.1    Pitcher, G.M.2    Henry, J.L.3
  • 60
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in conscious animals
    • Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16 (1983) 109-110
    • (1983) Pain , vol.16 , pp. 109-110
    • Zimmermann, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.