Aberrant overexpression of an epithelial marker, 14-3-3σ, in a subset of hematological malignancies

BMC Cancer

Volumn 7, Issue , 2007, Pages

  Motokura, Toru ^a   Nakamura, Yukari ^a   Sato, Hiroyuki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARF PROTEIN; BISULFITE; CELL SURFACE MARKER; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 2A; EPITHELIAL SURFACE MARKER; MESSENGER RNA; PROTEIN 14 3 3; PROTEIN P53; STRATIFIN; UNCLASSIFIED DRUG; ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; EXONUCLEASE; SFN PROTEIN, HUMAN; TUMOR MARKER; TUMOR PROTEIN;

ACUTE LEUKEMIA; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DNA METHYLATION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE MUTATION; GENE OVEREXPRESSION; GENETIC ANALYSIS; GENETIC IDENTIFICATION; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN CELL; IN VIVO STUDY; LYMPHOMA; NUCLEOTIDE SEQUENCE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR GROWTH; WESTERN BLOTTING; BIOSYNTHESIS; BLOOD DISEASE; CELL CULTURE; CELL CYCLE; GENETICS; METABOLISM; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE; UPREGULATION;

ADP-RIBOSYLATION FACTORS; BASE SEQUENCE; BLOTTING, WESTERN; CELL CYCLE; DNA METHYLATION; EXONUCLEASES; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P16; HEMATOLOGIC NEOPLASMS; HUMANS; NEOPLASM PROTEINS; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 38949208774     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-7-217     Document Type: Article

References (35)

1. Mackintosh C Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes Biochem J 2004, 381:329-342 1133837 15167810 10.1042/BJ20031332
2. Aitken A 14-3-3 proteins: A historic overview Semin Cancer Biol 2006, 16:162-172 10.1016/j.semcancer.2006.03.005 16678438
3. Hermeking H The 14-3-3 cancer connection Nat Rev Cancer 2003, 3:931-943 10.1038/nrc1230 14737123
4. Hermeking H Lengauer C Polyak K He TC Zhang L Thiagalingam S Kinzler KW Vogelstein B 14-3-3sigma is a p53-regulated inhibitor of G2/M progression Mol Cell 1997, 1:3-11 10.1016/S1097-2765(00)80002-7 9659898
5. Chan TA Hermeking H Lengauer C Kinzler KW Vogelstein B 14-3-3sigma is required to prevent mitotic catastrophe after DNA damage Nature 1999, 401:616-620 10.1038/44188 10524633
6. Prasad GL Valverius EM McDuffie E Cooper HL Complementary DNA cloning of a novel epithelial cell marker protein, HME1, that may be down-regulated in neoplastic mammary cells Cell Growth Differ 1992, 3:507-513 1390337
7. Dellambra E Golisano O Bondanza S Siviero E Lacal P Molinari M D'Atri S De Luca M Downregulation of 14-3-3sigma prevents clonal evolution and leads to immortalization of primary human keratinocytes J Cell Biol 2000, 149:1117-1130 10.1083/jcb.149.5.1117 10831615
8. Ferguson AT Evron E Umbricht CB Pandita TK Chan TA Hermeking H Marks JR Lambers AR Futreal PA Stampfer MR Sukumar S High frequency of hypermethylation at the 14-3-3sigma locus leads to gene silencing in breast cancer Proc Natl Acad Sci USA 2000, 97:6049-6054 18556 10811911 10.1073/pnas.100566997
9. Umbricht CB Evron E Gabrielson E Ferguson A Marks J Sukumar S Hypermethylation of 14-3-3sigma (stratifin) is an early event in breast cancer Oncogene 2001, 20:3348-3353 10.1038/sj.onc.1204438 11423985
10. Iwata N Yamamoto H Sasaki S Itoh F Suzuki H Kikuchi T Kaneto H Iku S Ozeki I Karino Y Satoh T Toyota J Satoh M Endo T Imai K Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 sigma gene in human hepatocellular carcinoma Oncogene 2000, 19:5298-5302 10.1038/sj.onc.1203898 11077447
11. Gasco M Bell AK Heath V Sullivan A Smith P Hiller L Yulug I Numico G Merlano M Farrell PJ Tavassoli M Gusterson B Crook T Epigenetic inactivation of 14-3-3 sigma in oral carcinoma: Association with p16INK4a silencing and human papillomavirus negativity Cancer Res 2002, 62:2072-2076 11929827
12. Osada H Tatematsu Y Yatabe Y Nakagawa T Konishi H Harano T Tezel E Takada M Takahashi T Frequent and histological type-specific inactivation of 14-3-3sigma in human lung cancers Oncogene 2002, 21:2418-2424 10.1038/sj.onc.1205303 11948426
13. Urano T Saito T Tsukui T Fujita M Hosoi T Muramatsu M Ouchi Y Inoue S Efp targets 14-3-3sigma for proteolysis and promotes breast tumour growth Nature 2002, 417:871-875 10.1038/nature00826 12075357
14. Samuel T Weber HO Rauch P Verdoodt B Eppel JT McShea A Hermeking H Funk JO The G2/M regulator 14-3-3sigma prevents apoptosis through sequestration of Bax J Biol Chem 2001, 276:45201-45206 10.1074/ jbc.M106427200 11574543
15. Iacobuzio-Donahue CA Maitra A Olsen M Lowe AW van Heek NT Rosty C Walter K Sato N Parker A Ashfaq R Jaffee E Ryu B Jones J Eshleman JR Yeo CJ Cameron JL Kern SE Hruban RH Brown PO Goggins M Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays Am J Pathol 2003, 162:1151-1162 1851213 12651607
16. Ito Y Miyoshi E Uda E Yoshida H Uruno T Takamura Y Miya A Kobayashi K Matsuzuka F Matsuura N Kakudo K Kuma K Miyauchi A 14-3-3 sigma possibly plays a constitutive role in papillary carcinoma, but not in follicular tumor of the thyroid Cancer Lett 2003, 200:161-166 10.1016/ S0304-3835(03)00282-9 14568170
17. Nakayama H Sano T Motegi A Oyama T Nakajima T Increasing 14-3-3 sigma expression with declining estrogen receptor alpha and estrogen-responsive finger protein expression defines malignant progression of endometrial carcinoma Pathol Int 2005, 55:707-715 10.1111/ j.1440-1827.2005.01900.x 16271083
18. Sato H Nakamura Y Motokura T Differential 14-3-3sigma DNA methylation and expression in c-myc- and activated H-ras-transformed cells under r- and K-selection Cancer Lett 2006, 236:105-114 10.1016/ j.canlet.2005.05.004 15979784
19. Satoh J Tabunoki H Nanri Y Arima K Yamamura T Human astrocytes express 14-3-3 sigma in response to oxidative and DNA-damaging stresses Neurosci Res 2006, 56:61-72 10.1016/j.neures.2006.05.007 16797759
20. Bhatia K Siraj AK Hussain A Bu R Gutierrez MI The tumor suppressor gene 14-3-3 sigma is commonly methylated in normal and malignant lymphoid cells Cancer Epidemiol Biomarkers Prev 2003, 12:165-169 12582028
21. Moenkemann H Flammer J Wunderlich K Breipohl W Schild HH Golubnitschaja O Increased DNA breaks and up-regulation of both G1 and G2 checkpoint genes p21WAF1/CIP1 and 14-3-3 sigma in circulating leukocytes of glaucoma patients and vasospastic individuals Amino Acids 2005, 28:199-205 10.1007/s00726-005-0169-x 15723242
22. Uchimaru K Taniguchi T Yoshikawa M Asano S Arnold A Fujita T Motokura T Detection of cyclin D1 (bcl-1, PRAD1) overexpression by a simple competitive reverse transcription-polymerase chain reaction assay in t(11;14)(q13;q32)-bearing B-cell malignancies and/or mantle cell lymphoma Blood 1997, 89:965-974 9028328
23. Taniguchi T Chikatsu N Takahashi S Fujita A Uchimaru K Asano S Fujita T Motokura T Expression of p16INK4A and p14ARF in hematological malignancies Leukemia 1999, 13:1760-1769 10.1038/sj/leu/2401557 10557050
24. Hill HD Straka JG Protein determination using bicinchoninic acid in the presence of sulfhydryl reagents Anal Biochem 1988, 170:203-208 10.1016/ 0003-2697(88)90109-1 3389511
25. Uchimaru K Taniguchi T Yoshikawa M Fujinuma H Fujita T Motokura T Growth arrest associated with 12-o-tetradecanoylphorbol-13-acetate-induced hematopoietic differentiation with a defective retinoblastoma tumor suppressor-mediated pathway Leuk Res 1998, 22:413-420 10.1016/ S0145-2126(98)00004-6 9652727
26. Herman JG Graff JR Myohanen S Nelkin BD Baylin SB Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands Proc Natl Acad Sci USA 1996, 93:9821-9826 38513 8790415 10.1073/pnas.93.18.9821
27. Chikatsu N Nakamura Y Sato H Fujita T Asano S Motokura T p53 mutations and tetraploids under r- and K-selection Oncogene 2002, 21:3043-3049 10.1038/sj.onc.1205413 12082535
28. Sugano K Kyogoku A Fukayama N Ohkura H Shimosato Y Sekiya T Hayashi K Methods in laboratory investigation. Rapid and simple detection of c-Ki-ras2 gene codon 12 mutations by nonradioisotopic single-strand conformation polymorphism analysis Lab Invest 1993, 68:361-366 8450652
29. Kamijo T Zindy F Roussel MF Quelle DE Downing JR Ashmun RA Grosveld G Sherr CJ Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF Cell 1997, 91:649-659 10.1016/ S0092-8674(00)80452-3 9393858
30. Quelle DE Zindy F Ashmun RA Sherr CJ Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest Cell 1995, 83:993-1000 10.1016/ 0092-8674(95)90214-7 8521522
31. Drexler HG Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia-lymphoma cells Leukemia 1998, 12:845-859 10.1038/sj.leu.2401043 9639410
32. Nakamura Y Sato H Motokura T Development of multidrug resistance due to multiple factors including P-glycoprotein overexpression under K-selection after MYC and HRAS oncogene activation Int J Cancer 2006, 118:2448-2454 10.1002/ijc.21691 16353156
33. Liu Y Liu H Han B Zhang JT Identification of 14-3-3sigma as a contributor to drug resistance in human breast cancer cells using functional proteomic analysis Cancer Res 2006, 66:3248-3255 10.1158/ 0008-5472.CAN-05-3801 16540677
34. Sanchez-Aguilera A Sanchez-Beato M Garcia JF Prieto I Pollan M Piris MA p14ARF nuclear overexpression in aggressive B-cell lymphomas is a sensor of malfunction of the common tumor suppressor pathways Blood 2002, 99:1411-1418 10.1182/blood.V99.4.1411 11830494
35. Guweidhi A Kleeff J Giese N El Fitori J Ketterer K Giese T Buchler MW Korc M Friess H Enhanced expression of 14-3-3sigma in pancreatic cancer and its role in cell cycle regulation and apoptosis Carcinogenesis 2004, 25:1575-1585 10.1093/carcin/bgh159 15073049