Orally active 1,2,4-trioxepanes: Synthesis and antimalarial activity of a series of 7-arylvinyl-1,2,4-trioxepanes against multidrug-resistant Plasmodium yoelii in Swiss mice

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 4, 2008, Pages 1816-1821

  Singh, Chandan ^a   Pandey, Shilpi ^a   Sharma, Malvika ^a   Puri, Sunil K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

1,2,4 Trioxane; 1,2,4 Trioxepane; Malaria chemotherapy; Multidrug resistant Plasmodium yoelii; Orally active

Indexed keywords

ANTIMALARIAL AGENT; OXEPANE DERIVATIVE;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; MOUSE; NONHUMAN; PARASITEMIA; PLASMODIUM YOELII;

ANIMALS; ANTIMALARIALS; DRUG RESISTANCE, MULTIPLE; HETEROCYCLIC COMPOUNDS, 1-RING; MICE; PARASITEMIA; PLASMODIUM YOELII; PROPANOLS; STRUCTURE-ACTIVITY RELATIONSHIP;

MUS; PLASMODIUM YOELII; PLASMODIUM YOELII NIGERIENSIS;

EID: 38949188265     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.11.012     Document Type: Article

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