-
1
-
-
0030897031
-
Structure of 20S proteasome from yeast at 2.4 A resolution
-
Groll, M., Ditzel, L., Lowe, J., Stock, D., Bochtler, M., Bartunik, H. D., and Huber, R. (1997) Structure of 20S proteasome from yeast at 2.4 A resolution. Nature 386, 463-471.
-
(1997)
Nature
, vol.386
, pp. 463-471
-
-
Groll, M.1
Ditzel, L.2
Lowe, J.3
Stock, D.4
Bochtler, M.5
Bartunik, H.D.6
Huber, R.7
-
2
-
-
0032867676
-
The 26S proteasome: A molecular machine designed for controlled proteolysis
-
Voges, D., Zwickl, P., and Baumeister, W. (1999) The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu. Rev. Biochem. 68, 1015-1068.
-
(1999)
Annu. Rev. Biochem
, vol.68
, pp. 1015-1068
-
-
Voges, D.1
Zwickl, P.2
Baumeister, W.3
-
4
-
-
0030457014
-
Ubiquitin-dependent protein degradation
-
Hochstrasser, M. (1996) Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30, 405-439.
-
(1996)
Annu. Rev. Genet
, vol.30
, pp. 405-439
-
-
Hochstrasser, M.1
-
5
-
-
0030926777
-
Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation
-
Craiu, A., Gaczynska, M., Akopian, T., Gramm, C. F., Fenteany, G., Goldberg, A. L., and Rock, K. L. (1997) Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation. J. Biol. Chem. 272, 13437-13445.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 13437-13445
-
-
Craiu, A.1
Gaczynska, M.2
Akopian, T.3
Gramm, C.F.4
Fenteany, G.5
Goldberg, A.L.6
Rock, K.L.7
-
6
-
-
0025123346
-
The multicatalytic proteinase complex, a major extralysosomal proteolytic system
-
Orlowski, M. (1990) The multicatalytic proteinase complex, a major extralysosomal proteolytic system. Biochemistry 29, 10289-10297.
-
(1990)
Biochemistry
, vol.29
, pp. 10289-10297
-
-
Orlowski, M.1
-
7
-
-
0030016595
-
Structure and functions of the 20S and 26S proteasomes
-
Coux, O., Tanaka, K., and Goldberg, A. L. (1996) Structure and functions of the 20S and 26S proteasomes. Annu. Rev. Biochem. 65, 801-847.
-
(1996)
Annu. Rev. Biochem
, vol.65
, pp. 801-847
-
-
Coux, O.1
Tanaka, K.2
Goldberg, A.L.3
-
8
-
-
0034864799
-
Proteasome inhibitors: From research tools to drug candidates
-
Kisselev, A. F., and Goldberg, A. L. (2001) Proteasome inhibitors: from research tools to drug candidates. Chem. Biol. 8, 739-758.
-
(2001)
Chem. Biol
, vol.8
, pp. 739-758
-
-
Kisselev, A.F.1
Goldberg, A.L.2
-
9
-
-
0034091579
-
Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus
-
Duan, D., Yue, Y., Yan, Z., Yang, J., and Engelhardt, J. F. (2000) Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus. J. Clin. Invest. 105, 1573-1587.
-
(2000)
J. Clin. Invest
, vol.105
, pp. 1573-1587
-
-
Duan, D.1
Yue, Y.2
Yan, Z.3
Yang, J.4
Engelhardt, J.F.5
-
11
-
-
0035037237
-
Hydrodynamics-based gene delivery
-
Liu, D., and Knapp, J. E. (2001) Hydrodynamics-based gene delivery. Curr. Opin. Mol. Ther. 3, 192-197.
-
(2001)
Curr. Opin. Mol. Ther
, vol.3
, pp. 192-197
-
-
Liu, D.1
Knapp, J.E.2
-
12
-
-
0037309716
-
Barriers to non viral gene delivery
-
Wiethoff, C. M., and Middaugh, C. R. (2003) Barriers to non viral gene delivery. J. Pharm. Sci. 92, 203-217.
-
(2003)
J. Pharm. Sci
, vol.92
, pp. 203-217
-
-
Wiethoff, C.M.1
Middaugh, C.R.2
-
13
-
-
27544454761
-
The proteasome metabolizes peptide-mediated nonviral gene delivery systems
-
Kim, J., Chen, C.-P., and Rice, K. G. (2005) The proteasome metabolizes peptide-mediated nonviral gene delivery systems. Gene Ther. 12, 1581-1590.
-
(2005)
Gene Ther
, vol.12
, pp. 1581-1590
-
-
Kim, J.1
Chen, C.-P.2
Rice, K.G.3
-
14
-
-
22744459051
-
Peptidyl vinyl ester derivatives: New class of selective inhibitors of proteasome trypsin-like activity
-
Marastoni, M., Baldisserotto, A., Cellini, S., Gavioli, R., and Tomatis, R. (2005) Peptidyl vinyl ester derivatives: new class of selective inhibitors of proteasome trypsin-like activity. J. Med. Chem. 48, 5038-5042.
-
(2005)
J. Med. Chem
, vol.48
, pp. 5038-5042
-
-
Marastoni, M.1
Baldisserotto, A.2
Cellini, S.3
Gavioli, R.4
Tomatis, R.5
-
15
-
-
33646202322
-
P3 and P4 position analysis of vinyl ester pseudopeptide proteasome inhibitors
-
Marastoni, M., Baldisserotto, A., Trapella, C., Gavioli, R., and Tomatis, R. (2006) P3 and P4 position analysis of vinyl ester pseudopeptide proteasome inhibitors. Bioorg. Med. Chem. Lett. 16, 3125-3130.
-
(2006)
Bioorg. Med. Chem. Lett
, vol.16
, pp. 3125-3130
-
-
Marastoni, M.1
Baldisserotto, A.2
Trapella, C.3
Gavioli, R.4
Tomatis, R.5
-
16
-
-
33746837791
-
Synthesis and biological evaluation of new vinyl ester pseudotripeptide proteasome inhibitors
-
Marastoni, M., Baldisserotto, A., Trapella, C., Gavioli, R., and Tomatis, R. (2006) Synthesis and biological evaluation of new vinyl ester pseudotripeptide proteasome inhibitors. Eur. J. Med. Chem. 41, 978-984.
-
(2006)
Eur. J. Med. Chem
, vol.41
, pp. 978-984
-
-
Marastoni, M.1
Baldisserotto, A.2
Trapella, C.3
Gavioli, R.4
Tomatis, R.5
-
17
-
-
34248182988
-
Glutamine vinyl ester proteasome inhibitors selective for trypsin-like (beta2) subunit
-
Baldisserotto, A., Marastoni, M., Trapella, C., Gavioli, R., Ferretti, V., Pretto, L., and Tomatis, R. (2007) Glutamine vinyl ester proteasome inhibitors selective for trypsin-like (beta2) subunit. Eur. J. Med. Chem. 42, 586-592.
-
(2007)
Eur. J. Med. Chem
, vol.42
, pp. 586-592
-
-
Baldisserotto, A.1
Marastoni, M.2
Trapella, C.3
Gavioli, R.4
Ferretti, V.5
Pretto, L.6
Tomatis, R.7
-
18
-
-
85004872164
-
An efficient synthesis of optically active α-(t-butoxycarbonylamino)-aldehydes from α-amino acids
-
Fehrentz, J.-A., and Castro, B. (1983) An efficient synthesis of optically active α-(t-butoxycarbonylamino)-aldehydes from α-amino acids. Synthesis 8, 676-678.
-
(1983)
Synthesis
, vol.8
, pp. 676-678
-
-
Fehrentz, J.-A.1
Castro, B.2
-
19
-
-
0037386706
-
Synthesis of chiral 3,4-disubstituted pyrroles from L-amino acids
-
Hover, J. A., Bock, C. W., and Bhat, K. L. (2003) Synthesis of chiral 3,4-disubstituted pyrroles from L-amino acids. Heterocycles 60, 791-798.
-
(2003)
Heterocycles
, vol.60
, pp. 791-798
-
-
Hover, J.A.1
Bock, C.W.2
Bhat, K.L.3
-
20
-
-
0034616214
-
A potent new class of reductively activated peptide gene delivery agents
-
McKenzie, D. L., Kwok, K. Y., and Rice, K. G. (2000) A potent new class of reductively activated peptide gene delivery agents. J. Biol. Chem. 275, 9970-9977.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 9970-9977
-
-
McKenzie, D.L.1
Kwok, K.Y.2
Rice, K.G.3
-
21
-
-
0031834992
-
Stability of peptide-condensed plasmid DNA formulations
-
Adami, R. C., Collard, W. T., Gupta, S. A., Kwok, K. Y., Bonadio, J., and Rice, K. G. (1998) Stability of peptide-condensed plasmid DNA formulations. J. Pharm. Sci. 87, 678-683.
-
(1998)
J. Pharm. Sci
, vol.87
, pp. 678-683
-
-
Adami, R.C.1
Collard, W.T.2
Gupta, S.A.3
Kwok, K.Y.4
Bonadio, J.5
Rice, K.G.6
-
22
-
-
0022186670
-
Measurement of protein using bicinchoninic acid
-
Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Gartner, F. H., Provenzano, M. D., Fujumoto, E. K., Goeke, N. M., Olson, B. J., and Klenk, D. C. (1985) Measurement of protein using bicinchoninic acid. Anal. Biochem. 150, 76-85.
-
(1985)
Anal. Biochem
, vol.150
, pp. 76-85
-
-
Smith, P.K.1
Krohn, R.I.2
Hermanson, G.T.3
Mallia, A.K.4
Gartner, F.H.5
Provenzano, M.D.6
Fujumoto, E.K.7
Goeke, N.M.8
Olson, B.J.9
Klenk, D.C.10
-
23
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann, T. (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63.
-
(1983)
J. Immunol. Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
24
-
-
0030041813
-
Synthesis of ketones and aldehydes via reactions of Weinreb-type amides on solid support
-
Dinh, T. Q., and Armstrong, R. W. (1996) Synthesis of ketones and aldehydes via reactions of Weinreb-type amides on solid support. Tetrahedron Lett. 37, 1161-1164.
-
(1996)
Tetrahedron Lett
, vol.37
, pp. 1161-1164
-
-
Dinh, T.Q.1
Armstrong, R.W.2
-
25
-
-
0000883039
-
Solid phase synthesis of C-terminal peptide aldehydes
-
Fehrentz, J. A., Paris, M., Heitz, A., Velek, J., Winternitz, F., and Martinez, J. (1997) Solid phase synthesis of C-terminal peptide aldehydes. J. Org. Chem. 62, 6792-6796.
-
(1997)
J. Org. Chem
, vol.62
, pp. 6792-6796
-
-
Fehrentz, J.A.1
Paris, M.2
Heitz, A.3
Velek, J.4
Winternitz, F.5
Martinez, J.6
-
26
-
-
0028825668
-
Improved solid phase synthesis of C-terminal peptide aldehydes
-
Fehrentz, J.-A., Paris, M., Heitz, A., Velek, J., Liu, C.-F., Winternitz, F., and Martinez, J. (1995) Improved solid phase synthesis of C-terminal peptide aldehydes. Tetrahedron Lett. 36, 7871-7874.
-
(1995)
Tetrahedron Lett
, vol.36
, pp. 7871-7874
-
-
Fehrentz, J.-A.1
Paris, M.2
Heitz, A.3
Velek, J.4
Liu, C.-F.5
Winternitz, F.6
Martinez, J.7
-
27
-
-
0031048568
-
Peptide-mediated gene delivery: Influence of peptide structure on gene expression
-
Wadhwa, M. S., Collard, W. T., Adami, R. C., McKenzie, D. L., and Rice, K. G. (1997) Peptide-mediated gene delivery: influence of peptide structure on gene expression. Bioconjugate Chem. 8, 81-88.
-
(1997)
Bioconjugate Chem
, vol.8
, pp. 81-88
-
-
Wadhwa, M.S.1
Collard, W.T.2
Adami, R.C.3
McKenzie, D.L.4
Rice, K.G.5
-
28
-
-
0027980319
-
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
-
Rock, K. L., Gramm, C., Rothstein, L., Clark, K., Stein, R., Dick, L., Hwang, D., and Goldberg, A. L. (1994) Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 78, 761-771.
-
(1994)
Cell
, vol.78
, pp. 761-771
-
-
Rock, K.L.1
Gramm, C.2
Rothstein, L.3
Clark, K.4
Stein, R.5
Dick, L.6
Hwang, D.7
Goldberg, A.L.8
-
29
-
-
0141704418
-
The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites
-
Kisselev, A. F., Garcia-Calvo, M., Overkleeft, H. S., Peterson, E., Pennington, M. W., Ploegh, H. L., Thornberry, N. A., and Goldberg, A. L. (2003) The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites. J. Biol. Chem. 278, 35869-35877.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 35869-35877
-
-
Kisselev, A.F.1
Garcia-Calvo, M.2
Overkleeft, H.S.3
Peterson, E.4
Pennington, M.W.5
Ploegh, H.L.6
Thornberry, N.A.7
Goldberg, A.L.8
-
30
-
-
0033197542
-
Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown
-
Kisselev, A. F., Akopian, T. N., Castillo, V., and Goldberg, A. L. (1999) Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown. Mol. Cell 4, 395-402.
-
(1999)
Mol. Cell
, vol.4
, pp. 395-402
-
-
Kisselev, A.F.1
Akopian, T.N.2
Castillo, V.3
Goldberg, A.L.4
|