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Volumn 19, Issue 1, 2008, Pages 370-376

A novel class of intrinsic proteasome inhibitory gene transfer peptides

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BENZYLOXYCARBONYLLEUCYLLEUCYLNORVALINAL; CYSTEINE; LYSINE; MG 115; PROTEASOME; PROTEASOME INHIBITOR; TRIPEPTIDE; TRYPTOPHAN; UNCLASSIFIED DRUG;

EID: 38949133405     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc700362b     Document Type: Article
Times cited : (8)

References (30)
  • 2
    • 0032867676 scopus 로고    scopus 로고
    • The 26S proteasome: A molecular machine designed for controlled proteolysis
    • Voges, D., Zwickl, P., and Baumeister, W. (1999) The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu. Rev. Biochem. 68, 1015-1068.
    • (1999) Annu. Rev. Biochem , vol.68 , pp. 1015-1068
    • Voges, D.1    Zwickl, P.2    Baumeister, W.3
  • 4
    • 0030457014 scopus 로고    scopus 로고
    • Ubiquitin-dependent protein degradation
    • Hochstrasser, M. (1996) Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30, 405-439.
    • (1996) Annu. Rev. Genet , vol.30 , pp. 405-439
    • Hochstrasser, M.1
  • 5
    • 0030926777 scopus 로고    scopus 로고
    • Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation
    • Craiu, A., Gaczynska, M., Akopian, T., Gramm, C. F., Fenteany, G., Goldberg, A. L., and Rock, K. L. (1997) Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation. J. Biol. Chem. 272, 13437-13445.
    • (1997) J. Biol. Chem , vol.272 , pp. 13437-13445
    • Craiu, A.1    Gaczynska, M.2    Akopian, T.3    Gramm, C.F.4    Fenteany, G.5    Goldberg, A.L.6    Rock, K.L.7
  • 6
    • 0025123346 scopus 로고
    • The multicatalytic proteinase complex, a major extralysosomal proteolytic system
    • Orlowski, M. (1990) The multicatalytic proteinase complex, a major extralysosomal proteolytic system. Biochemistry 29, 10289-10297.
    • (1990) Biochemistry , vol.29 , pp. 10289-10297
    • Orlowski, M.1
  • 7
    • 0030016595 scopus 로고    scopus 로고
    • Structure and functions of the 20S and 26S proteasomes
    • Coux, O., Tanaka, K., and Goldberg, A. L. (1996) Structure and functions of the 20S and 26S proteasomes. Annu. Rev. Biochem. 65, 801-847.
    • (1996) Annu. Rev. Biochem , vol.65 , pp. 801-847
    • Coux, O.1    Tanaka, K.2    Goldberg, A.L.3
  • 8
    • 0034864799 scopus 로고    scopus 로고
    • Proteasome inhibitors: From research tools to drug candidates
    • Kisselev, A. F., and Goldberg, A. L. (2001) Proteasome inhibitors: from research tools to drug candidates. Chem. Biol. 8, 739-758.
    • (2001) Chem. Biol , vol.8 , pp. 739-758
    • Kisselev, A.F.1    Goldberg, A.L.2
  • 9
    • 0034091579 scopus 로고    scopus 로고
    • Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus
    • Duan, D., Yue, Y., Yan, Z., Yang, J., and Engelhardt, J. F. (2000) Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus. J. Clin. Invest. 105, 1573-1587.
    • (2000) J. Clin. Invest , vol.105 , pp. 1573-1587
    • Duan, D.1    Yue, Y.2    Yan, Z.3    Yang, J.4    Engelhardt, J.F.5
  • 11
    • 0035037237 scopus 로고    scopus 로고
    • Hydrodynamics-based gene delivery
    • Liu, D., and Knapp, J. E. (2001) Hydrodynamics-based gene delivery. Curr. Opin. Mol. Ther. 3, 192-197.
    • (2001) Curr. Opin. Mol. Ther , vol.3 , pp. 192-197
    • Liu, D.1    Knapp, J.E.2
  • 12
    • 0037309716 scopus 로고    scopus 로고
    • Barriers to non viral gene delivery
    • Wiethoff, C. M., and Middaugh, C. R. (2003) Barriers to non viral gene delivery. J. Pharm. Sci. 92, 203-217.
    • (2003) J. Pharm. Sci , vol.92 , pp. 203-217
    • Wiethoff, C.M.1    Middaugh, C.R.2
  • 13
    • 27544454761 scopus 로고    scopus 로고
    • The proteasome metabolizes peptide-mediated nonviral gene delivery systems
    • Kim, J., Chen, C.-P., and Rice, K. G. (2005) The proteasome metabolizes peptide-mediated nonviral gene delivery systems. Gene Ther. 12, 1581-1590.
    • (2005) Gene Ther , vol.12 , pp. 1581-1590
    • Kim, J.1    Chen, C.-P.2    Rice, K.G.3
  • 14
    • 22744459051 scopus 로고    scopus 로고
    • Peptidyl vinyl ester derivatives: New class of selective inhibitors of proteasome trypsin-like activity
    • Marastoni, M., Baldisserotto, A., Cellini, S., Gavioli, R., and Tomatis, R. (2005) Peptidyl vinyl ester derivatives: new class of selective inhibitors of proteasome trypsin-like activity. J. Med. Chem. 48, 5038-5042.
    • (2005) J. Med. Chem , vol.48 , pp. 5038-5042
    • Marastoni, M.1    Baldisserotto, A.2    Cellini, S.3    Gavioli, R.4    Tomatis, R.5
  • 16
    • 33746837791 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of new vinyl ester pseudotripeptide proteasome inhibitors
    • Marastoni, M., Baldisserotto, A., Trapella, C., Gavioli, R., and Tomatis, R. (2006) Synthesis and biological evaluation of new vinyl ester pseudotripeptide proteasome inhibitors. Eur. J. Med. Chem. 41, 978-984.
    • (2006) Eur. J. Med. Chem , vol.41 , pp. 978-984
    • Marastoni, M.1    Baldisserotto, A.2    Trapella, C.3    Gavioli, R.4    Tomatis, R.5
  • 18
    • 85004872164 scopus 로고
    • An efficient synthesis of optically active α-(t-butoxycarbonylamino)-aldehydes from α-amino acids
    • Fehrentz, J.-A., and Castro, B. (1983) An efficient synthesis of optically active α-(t-butoxycarbonylamino)-aldehydes from α-amino acids. Synthesis 8, 676-678.
    • (1983) Synthesis , vol.8 , pp. 676-678
    • Fehrentz, J.-A.1    Castro, B.2
  • 19
    • 0037386706 scopus 로고    scopus 로고
    • Synthesis of chiral 3,4-disubstituted pyrroles from L-amino acids
    • Hover, J. A., Bock, C. W., and Bhat, K. L. (2003) Synthesis of chiral 3,4-disubstituted pyrroles from L-amino acids. Heterocycles 60, 791-798.
    • (2003) Heterocycles , vol.60 , pp. 791-798
    • Hover, J.A.1    Bock, C.W.2    Bhat, K.L.3
  • 20
    • 0034616214 scopus 로고    scopus 로고
    • A potent new class of reductively activated peptide gene delivery agents
    • McKenzie, D. L., Kwok, K. Y., and Rice, K. G. (2000) A potent new class of reductively activated peptide gene delivery agents. J. Biol. Chem. 275, 9970-9977.
    • (2000) J. Biol. Chem , vol.275 , pp. 9970-9977
    • McKenzie, D.L.1    Kwok, K.Y.2    Rice, K.G.3
  • 23
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann, T. (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 24
    • 0030041813 scopus 로고    scopus 로고
    • Synthesis of ketones and aldehydes via reactions of Weinreb-type amides on solid support
    • Dinh, T. Q., and Armstrong, R. W. (1996) Synthesis of ketones and aldehydes via reactions of Weinreb-type amides on solid support. Tetrahedron Lett. 37, 1161-1164.
    • (1996) Tetrahedron Lett , vol.37 , pp. 1161-1164
    • Dinh, T.Q.1    Armstrong, R.W.2
  • 27
    • 0031048568 scopus 로고    scopus 로고
    • Peptide-mediated gene delivery: Influence of peptide structure on gene expression
    • Wadhwa, M. S., Collard, W. T., Adami, R. C., McKenzie, D. L., and Rice, K. G. (1997) Peptide-mediated gene delivery: influence of peptide structure on gene expression. Bioconjugate Chem. 8, 81-88.
    • (1997) Bioconjugate Chem , vol.8 , pp. 81-88
    • Wadhwa, M.S.1    Collard, W.T.2    Adami, R.C.3    McKenzie, D.L.4    Rice, K.G.5
  • 28
    • 0027980319 scopus 로고
    • Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
    • Rock, K. L., Gramm, C., Rothstein, L., Clark, K., Stein, R., Dick, L., Hwang, D., and Goldberg, A. L. (1994) Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 78, 761-771.
    • (1994) Cell , vol.78 , pp. 761-771
    • Rock, K.L.1    Gramm, C.2    Rothstein, L.3    Clark, K.4    Stein, R.5    Dick, L.6    Hwang, D.7    Goldberg, A.L.8
  • 29
    • 0141704418 scopus 로고    scopus 로고
    • The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites
    • Kisselev, A. F., Garcia-Calvo, M., Overkleeft, H. S., Peterson, E., Pennington, M. W., Ploegh, H. L., Thornberry, N. A., and Goldberg, A. L. (2003) The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites. J. Biol. Chem. 278, 35869-35877.
    • (2003) J. Biol. Chem , vol.278 , pp. 35869-35877
    • Kisselev, A.F.1    Garcia-Calvo, M.2    Overkleeft, H.S.3    Peterson, E.4    Pennington, M.W.5    Ploegh, H.L.6    Thornberry, N.A.7    Goldberg, A.L.8
  • 30
    • 0033197542 scopus 로고    scopus 로고
    • Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown
    • Kisselev, A. F., Akopian, T. N., Castillo, V., and Goldberg, A. L. (1999) Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown. Mol. Cell 4, 395-402.
    • (1999) Mol. Cell , vol.4 , pp. 395-402
    • Kisselev, A.F.1    Akopian, T.N.2    Castillo, V.3    Goldberg, A.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.