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Volumn 28, Issue 2, 2008, Pages 200-213

Protective effect of Kalpaamruthaa in combating the oxidative stress posed by aflatoxin B1-induced hepatocellular carcinoma with special reference to flavonoid structure-activity relationship

Author keywords

Aflatoxin B1; Antioxidants; Flavonoids; Glutathione metabolizing enzymes; Kalpaamruthaa; Lipid peroxidation; Oxidative stress

Indexed keywords

AFLATOXIN B1; AYURVEDIC DRUG; CATALASE; EMBLICA OFFICINALIS EXTRACT; FLAVONOID; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; KALPAAMRUTHAA; LIPID PEROXIDE; MALONALDEHYDE; SEMECARPUS ANACARDIUM EXTRACT; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOL; UNCLASSIFIED DRUG;

EID: 38849161464     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2007.01615.x     Document Type: Article
Times cited : (37)

References (116)
  • 1
    • 0023667777 scopus 로고
    • Oxygen free radicals linked to many disease conditions
    • Marx JL. Oxygen free radicals linked to many disease conditions. Science 1985; 235: 529-31.
    • (1985) Science , vol.235 , pp. 529-531
    • Marx, J.L.1
  • 2
    • 0022559216 scopus 로고
    • Oxy-radicals and related species, their formation, lifetimes and reactions
    • Pryor W. Oxy-radicals and related species, their formation, lifetimes and reactions. Ann Rev Physiol 1986; 48: 657-67.
    • (1986) Ann Rev Physiol , vol.48 , pp. 657-667
    • Pryor, W.1
  • 3
    • 0033576675 scopus 로고    scopus 로고
    • More than one way to die: Apoptosis, necrosis and reactive oxygen damage
    • Fiers W, Beyaert R, Declercq W, Vandenabeele P. More than one way to die: Apoptosis, necrosis and reactive oxygen damage. Oncogene 1999; 18: 7719-30.
    • (1999) Oncogene , vol.18 , pp. 7719-7730
    • Fiers, W.1    Beyaert, R.2    Declercq, W.3    Vandenabeele, P.4
  • 4
    • 0032874845 scopus 로고    scopus 로고
    • Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defense against oxidative stress
    • Hayes JD, Mclellan LI. Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defense against oxidative stress. Free Radical Res 1999; 31: 273-300.
    • (1999) Free Radical Res , vol.31 , pp. 273-300
    • Hayes, J.D.1    Mclellan, L.I.2
  • 5
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications in diabetes
    • Baynes JW. Role of oxidative stress in development of complications in diabetes. Diabetes 1991; 40: 405-12.
    • (1991) Diabetes , vol.40 , pp. 405-412
    • Baynes, J.W.1
  • 7
    • 0023264732 scopus 로고
    • Subcellular effects of adriamycin in the heart: A concise review
    • Singal PK, Deally CMR, Weinberg LL. Subcellular effects of adriamycin in the heart: A concise review. J Mol Cell Cardiol 1987; 19: 817-28.
    • (1987) J Mol Cell Cardiol , vol.19 , pp. 817-828
    • Singal, P.K.1    Deally, C.M.R.2    Weinberg, L.L.3
  • 8
    • 0025334004 scopus 로고
    • Doxorubicin selectively inhibits muscle gene expression in cardiac muscle cells in vivo and in vitro
    • Ito H, Miller SC, Billingham ME, et al. Doxorubicin selectively inhibits muscle gene expression in cardiac muscle cells in vivo and in vitro. Proc Natl Acad Sci USA 1990; 87: 4275-9.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4275-4279
    • Ito, H.1    Miller, S.C.2    Billingham, M.E.3
  • 9
    • 12444252114 scopus 로고    scopus 로고
    • Host-pathogen interactions during apoptosis
    • Hasnain SE, Begum R, Ramaiah KVA, et al. Host-pathogen interactions during apoptosis. J Biosci 2003; 28: 101-10.
    • (2003) J Biosci , vol.28 , pp. 101-110
    • Hasnain, S.E.1    Begum, R.2    Ramaiah, K.V.A.3
  • 10
    • 0025126555 scopus 로고
    • Role of free radicals and catalytic metal ions in human disease - An overview
    • Halliwell B, Gutteridge JMC. Role of free radicals and catalytic metal ions in human disease - an overview. Methods Enzymol 1990; 186: 1-185.
    • (1990) Methods Enzymol , vol.186 , pp. 1-185
    • Halliwell, B.1    Gutteridge, J.M.C.2
  • 12
    • 0001347025 scopus 로고
    • Epidemiology of Aflatoxin-related Disease
    • D.L. Eaton and J.D. Groopman Hall A.J. Wild C.P. eds Academic Press New York, USA
    • Hall AJ, Wild CP. Epidemiology of aflatoxin-related disease. In: Eaton DL, Groopman JD, eds. The Toxicology of Aflatoxins: Human Health, Veterinary and Agricultural Significance. New York, USA: Academic Press, 1994; 233-58.
    • (1994) The Toxicology of Aflatoxins: Human Health, Veterinary and Agricultural Significance , pp. 233-258
  • 13
    • 0031956813 scopus 로고    scopus 로고
    • The role of oxidative stress in chemical carcinogenesis
    • Klaunig JE, Xu Y, Isenberg JS, et al. The role of oxidative stress in chemical carcinogenesis. Environ Health Perspect 1998; 106: 289-95.
    • (1998) Environ Health Perspect , vol.106 , pp. 289-295
    • Klaunig, J.E.1    Xu, Y.2    Isenberg, J.S.3
  • 14
    • 0021243855 scopus 로고
    • Evidence for membrane-mediated chromosomal damage by aflatoxin B1 in human lymphocytes
    • Amstad P, Levy A, Emerit I, Cerutti P. Evidence for membrane-mediated chromosomal damage by aflatoxin B1 in human lymphocytes. Carcinogenesis 1984; 5: 719-23.
    • (1984) Carcinogenesis , vol.5 , pp. 719-723
    • Amstad, P.1    Levy, A.2    Emerit, I.3    Cerutti, P.4
  • 15
    • 0025612838 scopus 로고
    • Enzymatic and non-enzymatic formation of free radicals from aflatoxin B1
    • Kodama M, Inoue F, Akao M. Enzymatic and non-enzymatic formation of free radicals from aflatoxin B1. Free Radical Res Commun 1990; 10: 137-42.
    • (1990) Free Radical Res Commun , vol.10 , pp. 137-142
    • Kodama, M.1    Inoue, F.2    Akao, M.3
  • 16
    • 0029052918 scopus 로고
    • Involvement of reactive oxygen species in aflatoxin B1-induced cell injury in cultured rat hepatocytes
    • Shen HM, Ong CN, Shi CY. Involvement of reactive oxygen species in aflatoxin B1-induced cell injury in cultured rat hepatocytes. Toxicology 1995; 99: 115-23.
    • (1995) Toxicology , vol.99 , pp. 115-123
    • Shen, H.M.1    Ong, C.N.2    Shi, C.Y.3
  • 19
    • 0003822811 scopus 로고
    • Mrs. Bishen Singh, Mahendra Pal Singh Dehra Dun, India
    • Kirthikar KR, Basu BD. Indian Medicinal Plants. Dehra Dun, India: Mrs. Bishen Singh, Mahendra Pal Singh, 1975; 667-9.
    • (1975) Indian Medicinal Plants , pp. 667-669
    • Kirthikar, K.R.1    Basu, B.D.2
  • 20
    • 0015898761 scopus 로고
    • Study of complete regression in four cases of cancer
    • Vad BG. Study of complete regression in four cases of cancer. Indian Pract 1973; 26: 253-63.
    • (1973) Indian Pract , vol.26 , pp. 253-263
    • Vad, B.G.1
  • 21
    • 0002619281 scopus 로고
    • Recent advances in the isolation of structural elucidation of antineoplastic agents of higher plants
    • J.L. Beal and E. Reeinhard Cassady J.M. Chang C.J. Mclaughlin J.L. eds Hippokrates, Verlag
    • Cassady JM, Chang CJ, Mclaughlin JL. Recent advances in the isolation of structural elucidation of antineoplastic agents of higher plants. In: Beal JL, Reeinhard E, eds. Natural Products as Medicinal Agents. Hippokrates, Verlag, 1981; 93-124.
    • (1981) Natural Products As Medicinal Agents , pp. 93-124
    • Cassady, J.M.1    Chang, C.J.2    Mclaughlin, J.L.3
  • 22
    • 0018844259 scopus 로고
    • Antitumour activity of the extract of Semecarpus anacardium L. nuts in experimental tumour models
    • Chitinis MP, Bhatia KG, Phatak MK, Kesava Rao KV. Antitumour activity of the extract of Semecarpus anacardium L. nuts in experimental tumour models. Indian J Exp Biol 1980; 18: 6-8.
    • (1980) Indian J Exp Biol , vol.18 , pp. 6-8
    • Chitinis, M.P.1    Bhatia, K.G.2    Phatak, M.K.3    Kesava Rao, K.V.4
  • 23
    • 0031473591 scopus 로고    scopus 로고
    • Semecarpus anacardium nut extract induced changes in enzymic antioxidants studied in aflatoxin B caused hepatocellular carcinoma bearing Wistar rats
    • Premalatha B, Muthulakhsmi V, Vijayalakshmi T, Sachdanandam P. Semecarpus anacardium nut extract induced changes in enzymic antioxidants studied in aflatoxin B caused hepatocellular carcinoma bearing Wistar rats. Int J Pharmacognosy 1997; 35: 1-6.
    • (1997) Int J Pharmacognosy , vol.35 , pp. 1-6
    • Premalatha, B.1    Muthulakhsmi, V.2    Vijayalakshmi, T.3    Sachdanandam, P.4
  • 26
    • 0025277403 scopus 로고
    • Modificaton of clastogenicity of lead and aluminum in mouse bone marrow cells by dietary ingestion of Phyllanthus emblica fruit extract
    • Dhir H, Roy AK, Sharma A, Talukder G. Modificaton of clastogenicity of lead and aluminum in mouse bone marrow cells by dietary ingestion of Phyllanthus emblica fruit extract. Mut Res 1990; 241: 305-12.
    • (1990) Mut Res , vol.241 , pp. 305-312
    • Dhir, H.1    Roy, A.K.2    Sharma, A.3    Talukder, G.4
  • 27
    • 0026654256 scopus 로고
    • Modification of metal induced micronuclei formation in mouse bone marrow erythrocytes by phyllanthus fruit extract and ascorbic acid
    • Roy AK, Dhir H, Sharma A, Talukder G. Modification of metal induced micronuclei formation in mouse bone marrow erythrocytes by phyllanthus fruit extract and ascorbic acid. Toxicol Lett 1992; 62: 9-17.
    • (1992) Toxicol Lett , vol.62 , pp. 9-17
    • Roy, A.K.1    Dhir, H.2    Sharma, A.3    Talukder, G.4
  • 28
    • 0030657924 scopus 로고    scopus 로고
    • Dietary chemoprevention of clastogenic effects of 3,4-benz [a] pyrene by Emblica oficinalis Gaetrn. Fruit extract
    • Nandi P, Talukder G, Sharma A. Dietary chemoprevention of clastogenic effects of 3,4-benz [a] pyrene by Emblica oficinalis Gaetrn. Fruit extract. Br J Cancer 1997; 76: 1279-83.
    • (1997) Br J Cancer , vol.76 , pp. 1279-1283
    • Nandi, P.1    Talukder, G.2    Sharma, A.3
  • 29
    • 84996001121 scopus 로고
    • Antioxidant activity of Emblica officinalis
    • Jeena K, Kuttan R. Antioxidant activity of Emblica officinalis. J Clin Biochem Nutr 1995; 19: 63-70.
    • (1995) J Clin Biochem Nutr , vol.19 , pp. 63-70
    • Jeena, K.1    Kuttan, R.2
  • 30
    • 2742589144 scopus 로고    scopus 로고
    • Active constituents of Emblica officinalis: Part 1. The chemistry and antioxidative effects of two new hydrolysable tannins, Emblicanin A and B
    • Ghosal S, Tripathi VK, Chauhan S. Active constituents of Emblica officinalis: Part 1. The chemistry and antioxidative effects of two new hydrolysable tannins, Emblicanin A and B. Indian J Chem 1996; 35B: 941-8.
    • (1996) Indian J Chem , vol.35 B , pp. 941-948
    • Ghosal, S.1    Tripathi, V.K.2    Chauhan, S.3
  • 31
    • 0942289870 scopus 로고    scopus 로고
    • Evaluation of the phenolic contents and antioxidant capacities of two Malaysian floral honeys
    • Aljadi AM, Kamaruddin MY. Evaluation of the phenolic contents and antioxidant capacities of two Malaysian floral honeys. Food Chem 2004; 85: 513-8.
    • (2004) Food Chem , vol.85 , pp. 513-518
    • Aljadi, A.M.1    Kamaruddin, M.Y.2
  • 32
    • 0036727368 scopus 로고    scopus 로고
    • Antioxidant activities and total phenolics of different types of honey
    • Al-Mamary M, Al-Meeri A, Al-Habori M. Antioxidant activities and total phenolics of different types of honey. Nutr Res 2002; 22: 1041-7.
    • (2002) Nutr Res , vol.22 , pp. 1041-1047
    • Al-Mamary, M.1    Al-Meeri, A.2    Al-Habori, M.3
  • 33
    • 0037041949 scopus 로고    scopus 로고
    • Antioxidant capacity of honeys from various floral sources based on the determination of oxygen radical absorbance capacity and inhibition of in vitro lipoprotein oxidation in human serum samples
    • Gheldof N, Engeseth NJ. Antioxidant capacity of honeys from various floral sources based on the determination of oxygen radical absorbance capacity and inhibition of in vitro lipoprotein oxidation in human serum samples. J Agric Food Chem 2002; 50: 3050-5.
    • (2002) J Agric Food Chem , vol.50 , pp. 3050-3055
    • Gheldof, N.1    Engeseth, N.J.2
  • 34
    • 0037048732 scopus 로고    scopus 로고
    • Identification and quantification of antioxidant components of honeys from various floral sources
    • Gheldof N, Wang XH, Engeseth NH. Identification and quantification of antioxidant components of honeys from various floral sources. J Agric Food Chem 2002; 50: 5870-7.
    • (2002) J Agric Food Chem , vol.50 , pp. 5870-5877
    • Gheldof, N.1    Wang, X.H.2    Engeseth, N.H.3
  • 37
    • 1442360983 scopus 로고    scopus 로고
    • Phenolic acids and abscissic acid in Australian Eucalyptus honeys and their potential for floral authentication
    • Yao L, Jiang Y, Singanusong R, Datta N, Raymont K. Phenolic acids and abscissic acid in Australian Eucalyptus honeys and their potential for floral authentication. Food Chem 2003; 86: 169-77.
    • (2003) Food Chem , vol.86 , pp. 169-177
    • Yao, L.1    Jiang, Y.2    Singanusong, R.3    Datta, N.4    Raymont, K.5
  • 39
    • 0025192807 scopus 로고
    • The antitumor properties of honey
    • Gribel NV, Pashinskii VG. The antitumor properties of honey. Vopr Onkol 1990; 36: 704-9.
    • (1990) Vopr Onkol , vol.36 , pp. 704-709
    • Gribel, N.V.1    Pashinskii, V.G.2
  • 41
    • 0019322618 scopus 로고
    • Honey for necrotic malignant breast ulcers
    • Keast-Butler J. Honey for necrotic malignant breast ulcers. Lancet 1980; 11: 809.
    • (1980) Lancet , vol.11 , pp. 809
    • Keast-Butler, J.1
  • 42
    • 0026458746 scopus 로고
    • Effect of caffeic acid esters on carcinogen-induced mutagenicity and human colon adenocarcinoma cell growth
    • Rao CV, Desai D, Kaul B, Amin S, Reddy BS. Effect of caffeic acid esters on carcinogen-induced mutagenicity and human colon adenocarcinoma cell growth. Chem Biol Interact 1992; 84: 277-90.
    • (1992) Chem Biol Interact , vol.84 , pp. 277-290
    • Rao, C.V.1    Desai, D.2    Kaul, B.3    Amin, S.4    Reddy, B.S.5
  • 43
    • 0029047621 scopus 로고
    • Chemoprevention of colon carcinogenesis by phenylethyl-3-methylcaffeate
    • Rao CV, Desai D, Rivenson A, Simi B, Amin S, Reddy BS. Chemoprevention of colon carcinogenesis by phenylethyl-3-methylcaffeate. Cancer Res 1995; 55: 2310-5.
    • (1995) Cancer Res , vol.55 , pp. 2310-2315
    • Rao, C.V.1    Desai, D.2    Rivenson, A.3    Simi, B.4    Amin, S.5    Reddy, B.S.6
  • 44
    • 0027880285 scopus 로고
    • Inhibitory effect of caffeic acid esters on azoxymethane-induced biochemical changes and aberrant crypt foci formation in rat colon
    • Rao CV, Desai D, Simi B, Kulkarni N, Amin S, Reddy BS. Inhibitory effect of caffeic acid esters on azoxymethane-induced biochemical changes and aberrant crypt foci formation in rat colon. Cancer Res 1993; 53: 4182-8.
    • (1993) Cancer Res , vol.53 , pp. 4182-4188
    • Rao, C.V.1    Desai, D.2    Simi, B.3    Kulkarni, N.4    Amin, S.5    Reddy, B.S.6
  • 46
    • 0004295113 scopus 로고
    • 2nd edn. India: The Indian Medical Practitioners Co-Operative Pharmacy and Stores Ltd, 1972
    • Formulary of Siddha Medicine, 2nd edn. India: The Indian Medical Practitioners Co-Operative Pharmacy and Stores Ltd, 1972, pp. 197.
    • (1972) Formulary of Siddha Medicine , pp. 197
  • 47
    • 0025163020 scopus 로고
    • A single dose - Response effect of aflatoxin B1 on rapid liver cancer induction in two strains of rats
    • Angsubhakorn S, Get-Ngern P, Miyamoto M, Bhamarapravati N. A single dose - response effect of aflatoxin B1 on rapid liver cancer induction in two strains of rats. Int J Cancer 1990; 46: 664-8.
    • (1990) Int J Cancer , vol.46 , pp. 664-668
    • Angsubhakorn, S.1    Get-Ngern, P.2    Miyamoto, M.3    Bhamarapravati, N.4
  • 48
    • 0031238382 scopus 로고    scopus 로고
    • Modulating effect of Semecarpus anacardium Linn. nut extract on glucose metabolizing enzymes in aflatoxin B1-induced experimental hepatocellular carcinoma
    • Premalatha B, Sujatha V, Sachdanandam P. Modulating effect of Semecarpus anacardium Linn. nut extract on glucose metabolizing enzymes in aflatoxin B1-induced experimental hepatocellular carcinoma. Pharmacol Res 1997; 36: 187-92.
    • (1997) Pharmacol Res , vol.36 , pp. 187-192
    • Premalatha, B.1    Sujatha, V.2    Sachdanandam, P.3
  • 50
    • 0017065248 scopus 로고
    • Simple fluorimetric assay for lipid peroxidation in blood plasma
    • Yagi K. Simple fluorimetric assay for lipid peroxidation in blood plasma. Biochem Med 1976; 15: 212-5.
    • (1976) Biochem Med , vol.15 , pp. 212-215
    • Yagi, K.1
  • 51
  • 52
    • 0023261434 scopus 로고
    • Decreased lipid peroxidation in the rat kidney during gestation
    • Devasagayam TPA, Tarachand O. Decreased lipid peroxidation in the rat kidney during gestation. Biochem Biophys Res Commun 1987; 145: 134-8.
    • (1987) Biochem Biophys Res Commun , vol.145 , pp. 134-138
    • Devasagayam, T.P.A.1    Tarachand, O.2
  • 53
    • 0016272750 scopus 로고
    • Involvement of superoxide anion radical in the autooxidation of pyrogallol and a convenient assay for superoxide dismutase
    • Marklund S, Marklund G. Involvement of superoxide anion radical in the autooxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974; 47: 469-74.
    • (1974) Eur J Biochem , vol.47 , pp. 469-474
    • Marklund, S.1    Marklund, G.2
  • 54
    • 0015353270 scopus 로고
    • Colorimetric assay of catalase
    • Sinha AK. Colorimetric assay of catalase. Anal Biochem 1972; 47: 389-94.
    • (1972) Anal Biochem , vol.47 , pp. 389-394
    • Sinha, A.K.1
  • 55
    • 0015918166 scopus 로고
    • Selenium: Biochemical role as a component of glutathione peroxidase purification and assay
    • Rotruck JT, Pope AL, Ganther HE, et al. Selenium: Biochemical role as a component of glutathione peroxidase purification and assay. Science 1973; 179: 588-90.
    • (1973) Science , vol.179 , pp. 588-590
    • Rotruck, J.T.1    Pope, A.L.2    Ganther, H.E.3
  • 56
    • 0014668096 scopus 로고
    • Purification and properties of glutathione reductase of human erythrocytes
    • Staal GEJ, Visser J, Veeger C. Purification and properties of glutathione reductase of human erythrocytes. Biochim Biophys Acta 1969; 185: 39-48.
    • (1969) Biochim Biophys Acta , vol.185 , pp. 39-48
    • Staal, G.E.J.1    Visser, J.2    Veeger, C.3
  • 57
    • 0027251053 scopus 로고
    • The pecking order of free radicals and antioxidants: Lipid peroxidation, a-tocopherol and ascorbate
    • Buettner GR. The pecking order of free radicals and antioxidants: Lipid peroxidation, a-tocopherol and ascorbate. Arch Biochem Biophys 1993; 300: 535-43.
    • (1993) Arch Biochem Biophys , vol.300 , pp. 535-543
    • Buettner, G.R.1
  • 58
    • 0018327389 scopus 로고
    • Levels of glutathione, glutathione reductase and glutathione-S-transferase activities in rat lung and liver
    • Moron MS, Difieree JW, Mannerwik KB. Levels of glutathione, glutathione reductase and glutathione-S-transferase activities in rat lung and liver. Biochim Biophys Acta 1979; 582: 67-78.
    • (1979) Biochim Biophys Acta , vol.582 , pp. 67-78
    • Moron, M.S.1    Difieree, J.W.2    Mannerwik, K.B.3
  • 59
    • 0000147996 scopus 로고
    • Chemical estimation of vitamin E in tissue and a-tocopherol content of normal tissues
    • Quaife MC, Dju MY. Chemical estimation of vitamin E in tissue and a-tocopherol content of normal tissues. J Biol Chem 1948; 180: 263-72.
    • (1948) J Biol Chem , vol.180 , pp. 263-272
    • Quaife, M.C.1    Dju, M.Y.2
  • 60
    • 0018369625 scopus 로고
    • Selected methods for the determination of ascorbic acid in animal cells, tissues and fluids
    • Omaye ST, Turabull JD, Sauberlich HE. Selected methods for the determination of ascorbic acid in animal cells, tissues and fluids. Meth Enzymol 1979; 62: 1-11.
    • (1979) Meth Enzymol , vol.62 , pp. 1-11
    • Omaye, S.T.1    Turabull, J.D.2    Sauberlich, H.E.3
  • 61
    • 77049201260 scopus 로고
    • Determination of uric acid in serum by a carbonate method
    • Caraway T. Determination of uric acid in serum by a carbonate method. Am J Clin Pathol 1955; 25: 840-5.
    • (1955) Am J Clin Pathol , vol.25 , pp. 840-845
    • Caraway, T.1
  • 62
    • 0022336547 scopus 로고
    • Mechanisms of lipid peroxidation
    • Girotti MW. Mechanisms of lipid peroxidation. Free Radical Biol Med 1985; 1: 87-95.
    • (1985) Free Radical Biol Med , vol.1 , pp. 87-95
    • Girotti, M.W.1
  • 63
    • 0030041836 scopus 로고    scopus 로고
    • Dietary influences on membrane function: Importance in protection against oxidative damage and disease
    • Wiseman H. Dietary influences on membrane function: Importance in protection against oxidative damage and disease. J Nutr Biochem 1996; 7: 2-15.
    • (1996) J Nutr Biochem , vol.7 , pp. 2-15
    • Wiseman, H.1
  • 64
    • 0029867672 scopus 로고    scopus 로고
    • Flavonoids chemistry, metabolism, cardioprotective effects, and dietary sources
    • Cook NC, Samman S. Flavonoids chemistry, metabolism, cardioprotective effects, and dietary sources. J Nutr Biochem 1996; 7: 66-76.
    • (1996) J Nutr Biochem , vol.7 , pp. 66-76
    • Cook, N.C.1    Samman, S.2
  • 67
    • 0020626421 scopus 로고
    • Flavonoids, a class of natural products of high pharmacological potency
    • Havsteen B. Flavonoids, a class of natural products of high pharmacological potency. Biochem Pharmacol 1983; 32: 1141-8.
    • (1983) Biochem Pharmacol , vol.32 , pp. 1141-1148
    • Havsteen, B.1
  • 68
    • 0026785423 scopus 로고
    • Flavonoids: Biochemical effects and therapeutic applications
    • Brandi ML. Flavonoids: Biochemical effects and therapeutic applications. Bone Mineral 1992; 19: S14.
    • (1992) Bone Mineral , vol.19
    • Brandi, M.L.1
  • 69
    • 0027724739 scopus 로고
    • The antioxidant properties of five O-(/3-Hydroxyethyl)-rutosides of the flavonoid mixture Venoruton
    • Haenen GRMM, Jansen FP, Bast A. The antioxidant properties of five O-(/ 3-Hydroxyethyl)-rutosides of the flavonoid mixture Venoruton. Phlebology 1993; 1 (Suppl.): 10-7.
    • (1993) Phlebology , vol.1 , Issue.SUPPL. , pp. 10-17
    • Haenen, G.R.M.M.1    Jansen, F.P.2    Bast, A.3
  • 71
    • 2742589144 scopus 로고    scopus 로고
    • Active constituents of Emblica officinalis: Part 1. The chemistry and antioxidative effects of two new hydrolysable tannins, Emblicanin A and B
    • Ghosal S, Tripathi VK, Chauhan S. Active constituents of Emblica officinalis: Part 1. The chemistry and antioxidative effects of two new hydrolysable tannins, Emblicanin A and B. Indian J Chem 1996; 35B: 941-8.
    • (1996) Indian J Chem , vol.35 B , pp. 941-948
    • Ghosal, S.1    Tripathi, V.K.2    Chauhan, S.3
  • 73
    • 0020626421 scopus 로고
    • Flavonoids, a class of natural products of high pharmacological potency
    • Havsteen B. Flavonoids, a class of natural products of high pharmacological potency. Biochem Pharmacol 1983; 32: 1141-8.
    • (1983) Biochem Pharmacol , vol.32 , pp. 1141-1148
    • Havsteen, B.1
  • 74
    • 0027291905 scopus 로고
    • Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands
    • Hertog MGL, Hollman PCH, Katan MB, Kromhout D. Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands. Nutr Cancer 1993; 20: 21-9.
    • (1993) Nutr Cancer , vol.20 , pp. 21-29
    • Hertog, M.G.L.1    Hollman, P.C.H.2    Katan, M.B.3    Kromhout, D.4
  • 75
    • 0016906546 scopus 로고
    • The flavonoids. A class of semi-essential food components: Their role in human nutrition
    • Kuehnau J. The flavonoids. A class of semi-essential food components: their role in human nutrition. World Rev Nutr Diet 1976; 24: 117-91.
    • (1976) World Rev Nutr Diet , vol.24 , pp. 117-191
    • Kuehnau, J.1
  • 76
    • 0028001597 scopus 로고
    • Influence of a series of natural flavonoids on free radical generating systems and oxidative stress
    • Sanz MJ, Ferrandiz ML, Cejudo M, et al. Influence of a series of natural flavonoids on free radical generating systems and oxidative stress. Xenobiotica 1994; 24: 689-99.
    • (1994) Xenobiotica , vol.24 , pp. 689-699
    • Sanz, M.J.1    Ferrandiz, M.L.2    Cejudo, M.3
  • 79
    • 0025004502 scopus 로고
    • Flavonoids as antioxidants: Determination of radical-scavenging efficiencies
    • L. Packer and A.N. Glazer Bors W. Heller W. Michel C. Saran M. eds Academic Press Inc. New York
    • Bors W, Heller W, Michel C, Saran M. Flavonoids as antioxidants: determination of radical-scavenging efficiencies. In: Packer L, Glazer AN, eds. Methods in Enzymology: Oxygen Radicals in Biological Systems. New York: Academic Press Inc., 1990; 343-55.
    • (1990) Methods in Enzymology: Oxygen Radicals in Biological Systems , pp. 343-355
  • 80
    • 0036379137 scopus 로고    scopus 로고
    • Emblica cascading antioxidant: A novel natural skin care ingredient
    • Chaudhuri RK. Emblica cascading antioxidant: A novel natural skin care ingredient. Skin Pharmacol Appl Skin Physiol 2002; 15: 374-80.
    • (2002) Skin Pharmacol Appl Skin Physiol , vol.15 , pp. 374-380
    • Chaudhuri, R.K.1
  • 81
    • 0017413691 scopus 로고
    • Superoxide dismutase and glutathione peroxidase activities in tumours
    • Peskin AV, Koen YM, Zbarsky IB. Superoxide dismutase and glutathione peroxidase activities in tumours. FEBS Lett 1977; 78: 41-5.
    • (1977) FEBS Lett , vol.78 , pp. 41-45
    • Peskin, A.V.1    Koen, Y.M.2    Zbarsky, I.B.3
  • 82
    • 0018749490 scopus 로고
    • Role of superoxide dismutase in cancer: A review
    • Oberley LW, Buettner NR. Role of superoxide dismutase in cancer: A review. Cancer Res 1979; 39: 1141-9.
    • (1979) Cancer Res , vol.39 , pp. 1141-1149
    • Oberley, L.W.1    Buettner, N.R.2
  • 84
    • 0017252234 scopus 로고
    • Enzymes defence against reactive oxygen derivatives II. Erythrocytes and tumour cells
    • Bozzi A, Mavelli I, Finazzi Agro A, et al. Enzymes defence against reactive oxygen derivatives II. Erythrocytes and tumour cells. Mol Cell Biochem 1976; 10: 11-6.
    • (1976) Mol Cell Biochem , vol.10 , pp. 11-16
    • Bozzi, A.1    Mavelli, I.2    Finazzi Agro, A.3
  • 85
    • 0009424743 scopus 로고
    • Catalse: A tetrameric enzyme with four tightly bound molecules of NADPH
    • Kirkman HN, Gaetani GF. Catalse: A tetrameric enzyme with four tightly bound molecules of NADPH. Proc Natl Acad Sci USA 1984; 81: 4343-7.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 4343-4347
    • Kirkman, H.N.1    Gaetani, G.F.2
  • 86
    • 0029909010 scopus 로고    scopus 로고
    • Neuroprotection by the metabolic antioxidant α-lipoic acid
    • Packer L, Tritschler HJ, Wessel K. Neuroprotection by the metabolic antioxidant α-lipoic acid. Free Radical Biol Med 1997; 22: 359-78.
    • (1997) Free Radical Biol Med , vol.22 , pp. 359-378
    • Packer, L.1    Tritschler, H.J.2    Wessel, K.3
  • 87
    • 0032571852 scopus 로고    scopus 로고
    • Enhancement of expression of stress proteins by agents that lower the levels of glutathione in cells
    • Ito H, Okamoto K, Kato K. Enhancement of expression of stress proteins by agents that lower the levels of glutathione in cells. Biochim Biophys Acta 1998; 1397: 223-30.
    • (1998) Biochim Biophys Acta , vol.1397 , pp. 223-230
    • Ito, H.1    Okamoto, K.2    Kato, K.3
  • 89
    • 0017749491 scopus 로고
    • Prolactin binding to 7,12-dimethylbenz(a)anthracene-induced mammary tumors and liver in diabetic rats
    • Smith RD, Hilf R, Senior AE. Prolactin binding to 7,12-dimethylbenz(a)anthracene-induced mammary tumors and liver in diabetic rats. Cancer Res 1977; 37: 4070-4.
    • (1977) Cancer Res , vol.37 , pp. 4070-4074
    • Smith, R.D.1    Hilf, R.2    Senior, A.E.3
  • 91
    • 0029890646 scopus 로고    scopus 로고
    • Relationship between glutathione and DL alpha-lipoic acid against cadmium-induced hepatotoxicity
    • Sumathi R, Baskaran G, Varalakshmi P. Relationship between glutathione and DL alpha-lipoic acid against cadmium-induced hepatotoxicity. Jpn J Med Sci Biol 1996; 49: 39-48.
    • (1996) Jpn J Med Sci Biol , vol.49 , pp. 39-48
    • Sumathi, R.1    Baskaran, G.2    Varalakshmi, P.3
  • 92
    • 0028839684 scopus 로고
    • Activation and selective inhibition of a cyclic AMP-specific phosphodiesterase, PDE-4D3
    • Alvarez R, Sette C, Yang D, et al. Activation and selective inhibition of a cyclic AMP-specific phosphodiesterase, PDE-4D3. Mol Pharmacol 1995; 48: 616-22.
    • (1995) Mol Pharmacol , vol.48 , pp. 616-622
    • Alvarez, R.1    Sette, C.2    Yang, D.3
  • 93
    • 0024595407 scopus 로고
    • Catalase and glutathione peroxidase are equally active in detoxification of hydrogen peroxide in human erythrocytes
    • Gaetani GF, Galiano S, Canepa L, Ferraris AM, Kirkman HN. Catalase and glutathione peroxidase are equally active in detoxification of hydrogen peroxide in human erythrocytes. Blood 1989; 73: 334-9.
    • (1989) Blood , vol.73 , pp. 334-339
    • Gaetani, G.F.1    Galiano, S.2    Canepa, L.3    Ferraris, A.M.4    Kirkman, H.N.5
  • 94
    • 0027982869 scopus 로고
    • Influence of vitamins A, C, and E and beta-carotene on aflatoxin B1 binding to DNA in woodchuck hepatocytes
    • Yu MW, Zhang YJ, Blaner WS, Santella RM. Influence of vitamins A, C, and E and beta-carotene on aflatoxin B1 binding to DNA in woodchuck hepatocytes. Cancer 1994; 73: 596-604.
    • (1994) Cancer , vol.73 , pp. 596-604
    • Yu, M.W.1    Zhang, Y.J.2    Blaner, W.S.3    Santella, R.M.4
  • 95
    • 0018368359 scopus 로고
    • The role of glutathione and glutathione S-transferase in the metabolism of chemical carcinogens and other electrophilic agents
    • Chasseaud LF. The role of glutathione and glutathione S-transferase in the metabolism of chemical carcinogens and other electrophilic agents. Adv Cancer Res 1979; 29: 175-274.
    • (1979) Adv Cancer Res , vol.29 , pp. 175-274
    • Chasseaud, L.F.1
  • 96
    • 0027763570 scopus 로고
    • Tissue glutathione, nutrition and oxidative stress
    • Bray TM, Taylor CG. Tissue glutathione, nutrition and oxidative stress. Can J Physiol Pharmacol 1993; 71: 746-51.
    • (1993) Can J Physiol Pharmacol , vol.71 , pp. 746-751
    • Bray, T.M.1    Taylor, C.G.2
  • 97
    • 0015851719 scopus 로고
    • Accumulation of hepatic mitochondria in 2-methyl-4-dimethyl-aminoazobenzene fed rats as a result of decreased degradation
    • Fiala ES, Kettering WG, Fiala S. Accumulation of hepatic mitochondria in 2-methyl-4-dimethyl-aminoazobenzene fed rats as a result of decreased degradation. Naturwissenschaften 1973; 60: 394-5.
    • (1973) Naturwissenschaften , vol.60 , pp. 394-395
    • Fiala, E.S.1    Kettering, W.G.2    Fiala, S.3
  • 98
    • 0018071643 scopus 로고
    • Glutathione synthesis and degradation in fetal and adult rat liver and Novikoff hepatoma
    • Wirth PJ, Thorgeirsson SS. Glutathione synthesis and degradation in fetal and adult rat liver and Novikoff hepatoma. Cancer Res 1978; 38: 2861-5.
    • (1978) Cancer Res , vol.38 , pp. 2861-2865
    • Wirth, P.J.1    Thorgeirsson, S.S.2
  • 99
    • 0028001597 scopus 로고
    • Influence of a series of natural flavonoids on free radical generating systems and oxidative stress
    • Sanz MJ, Ferrandiz ML, Cejudo M, et al. Influence of a series of natural flavonoids on free radical generating systems and oxidative stress. Xenobiotica 1994; 24: 689-99.
    • (1994) Xenobiotica , vol.24 , pp. 689-699
    • Sanz, M.J.1    Ferrandiz, M.L.2    Cejudo, M.3
  • 100
    • 0028300426 scopus 로고
    • Conjugation of glutathione and other thiols with bioreductively activated mitomycin C. Effect of thiols on the reductive activation rate
    • Sharma M, Tomasz M. Conjugation of glutathione and other thiols with bioreductively activated mitomycin C. Effect of thiols on the reductive activation rate. Chem Res Toxicol 1994; 7: 390-400.
    • (1994) Chem Res Toxicol , vol.7 , pp. 390-400
    • Sharma, M.1    Tomasz, M.2
  • 101
    • 0021776272 scopus 로고
    • Vitamin E: Interactions with free radicals and ascorbate
    • McCay PB. Vitamin E: Interactions with free radicals and ascorbate. Annu Rev Nutr 1985; 5: 323-40.
    • (1985) Annu Rev Nutr , vol.5 , pp. 323-340
    • McCay, P.B.1
  • 102
    • 0037505644 scopus 로고    scopus 로고
    • Analysis of glutathione: Implication in redox and detoxification
    • Pastore A, Federici G, Bertini E, Piemonte F. Analysis of glutathione: implication in redox and detoxification. Clin Chim Acta 2003; 333: 19-39.
    • (2003) Clin Chim Acta , vol.333 , pp. 19-39
    • Pastore, A.1    Federici, G.2    Bertini, E.3    Piemonte, F.4
  • 103
    • 0025192067 scopus 로고
    • Effect of aflatoxin B1 treatment in vivo on the in vitro activity of hepatic and extrahepatic glutathione S-transferase
    • Carrillo MC, Carnovale CE, Monti JA. Effect of aflatoxin B1 treatment in vivo on the in vitro activity of hepatic and extrahepatic glutathione S-transferase. Toxicol Lett 1990; 50: 107-16.
    • (1990) Toxicol Lett , vol.50 , pp. 107-116
    • Carrillo, M.C.1    Carnovale, C.E.2    Monti, J.A.3
  • 104
    • 0029873843 scopus 로고    scopus 로고
    • Pathological aspects of active oxygens/free radicals
    • Nakazawa H, Genka C, Fujishima M. Pathological aspects of active oxygens/ free radicals. Jpn J Physiol 1996; 46: 15-32.
    • (1996) Jpn J Physiol , vol.46 , pp. 15-32
    • Nakazawa, H.1    Genka, C.2    Fujishima, M.3
  • 105
    • 0029812476 scopus 로고    scopus 로고
    • Role of dietary phyto-oestrogens in the protection against cancer and heart disease
    • Wiseman H. Role of dietary phyto-oestrogens in the protection against cancer and heart disease. Biochem Soc Trans 1996; 24: 795-800.
    • (1996) Biochem Soc Trans , vol.24 , pp. 795-800
    • Wiseman, H.1
  • 106
    • 0028032306 scopus 로고
    • Vitamin E in the genesis and prevention of cancer. A review
    • Das S. Vitamin E in the genesis and prevention of cancer. A review. Acta Oncol 1994; 33: 615-9.
    • (1994) Acta Oncol , vol.33 , pp. 615-619
    • Das, S.1
  • 107
    • 0022402990 scopus 로고
    • Effect of retinoic acid, butylated hydroxytoluene, propylgallate and selenium on 2-acetylaminofluorene induced hepatotoxicity
    • Daoud AH, Griffin AC. Effect of retinoic acid, butylated hydroxytoluene, propylgallate and selenium on 2-acetylaminofluorene induced hepatotoxicity. Cancer Lett 1985; 29: 183-8.
    • (1985) Cancer Lett , vol.29 , pp. 183-188
    • Daoud, A.H.1    Griffin, A.C.2
  • 108
    • 0023139640 scopus 로고
    • Effect of vitamin E- and selenium-deficiency on rat liver chemiluminescence
    • Fraga CG, Arias RF, Llesuy SF, Koch OR, Boveris A. Effect of vitamin E- and selenium-deficiency on rat liver chemiluminescence. Biochem J 1987; 242: 383-6.
    • (1987) Biochem J , vol.242 , pp. 383-386
    • Fraga, C.G.1    Arias, R.F.2    Llesuy, S.F.3    Koch, O.R.4    Boveris, A.5
  • 109
    • 0018773972 scopus 로고
    • High-dose methylprednisolone, vitamin A, and vitamin C in rats bearing the rapidly growing Morris 7777 hepatoma
    • Cameron I, Grubbs B, Rogers W. High-dose methylprednisolone, vitamin A, and vitamin C in rats bearing the rapidly growing Morris 7777 hepatoma. Cancer Treat Rep 1979; 63: 477-83.
    • (1979) Cancer Treat Rep , vol.63 , pp. 477-483
    • Cameron, I.1    Grubbs, B.2    Rogers, W.3
  • 110
    • 0027251053 scopus 로고
    • The pecking order of free radicals and antioxidants: Lipid peroxidation, alpha-tocopherol, and ascorbate
    • Buettner GR. The pecking order of free radicals and antioxidants: Lipid peroxidation, alpha-tocopherol, and ascorbate. Arch Biochem Biophys 1993; 300: 535-43.
    • (1993) Arch Biochem Biophys , vol.300 , pp. 535-543
    • Buettner, G.R.1
  • 111
    • 0027973899 scopus 로고
    • The role of ascorbate in antioxidant protection of biomembranes: Interaction with vitamin E and coenzyme Q
    • Beyer RE. The role of ascorbate in antioxidant protection of biomembranes: Interaction with vitamin E and coenzyme Q. J Bioenerg Biomembr 1994; 26: 349-58.
    • (1994) J Bioenerg Biomembr , vol.26 , pp. 349-358
    • Beyer, R.E.1
  • 112
    • 0016586662 scopus 로고
    • Blocking the formation of N-nitroso compounds with ascorbic acid in vitro and in vivo
    • Mirvish SS. Blocking the formation of N-nitroso compounds with ascorbic acid in vitro and in vivo. Ann NY Acad Sci 1975; 258: 175-80.
    • (1975) Ann NY Acad Sci , vol.258 , pp. 175-180
    • Mirvish, S.S.1
  • 113
    • 0021954668 scopus 로고
    • The action of anticlastogens in human lymphocytes cultures and their modification by rat-liver S9 mix II. Studies with vitamin C and E
    • Gebhart E, Wagner H, Gziwok K, Behnsen H. The action of anticlastogens in human lymphocytes cultures and their modification by rat-liver S9 mix II. Studies with vitamin C and E. Mutat Res 1985; 49: 84-94.
    • (1985) Mutat Res , vol.49 , pp. 84-94
    • Gebhart, E.1    Wagner, H.2    Gziwok, K.3    Behnsen, H.4
  • 114
    • 85006110318 scopus 로고
    • Antagonistic activity of herbal drug (pyllanthus emblica) on cytological effects of environmental chemicals on mammalian cells
    • Giri AK, Banergee TS. Antagonistic activity of herbal drug (pyllanthus emblica) on cytological effects of environmental chemicals on mammalian cells. Cytologia 1986; 51: 375-80.
    • (1986) Cytologia , vol.51 , pp. 375-380
    • Giri, A.K.1    Banergee, T.S.2
  • 115
    • 0021833460 scopus 로고
    • Inhibition of BaP and BaP-transdihydrodiol metabolism and DNA binding in mouse lung explants by ellagic acid
    • Dixit R, Teel RW, Daniel FB, Stoner GD. Inhibition of BaP and BaP-transdihydrodiol metabolism and DNA binding in mouse lung explants by ellagic acid. Cancer Res 1985; 45: 2951-6.
    • (1985) Cancer Res , vol.45 , pp. 2951-2956
    • Dixit, R.1    Teel, R.W.2    Daniel, F.B.3    Stoner, G.D.4


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