Dietary influences on membrane function: Importance in protection against oxidative damage and disease

Journal of Nutritional Biochemistry

Volumn 7, Issue 1, 1996, Pages 2-15

  Wiseman, Helen ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Cancer; Cardiovascular disease; Dietary antioxidants; Dietary membrane modulators; Low density lipoprotein particles; Oxidative membrane damage

Indexed keywords

EID: 0030041836     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/0955-2863(95)00152-2     Document Type: Review

References (165)

1. Peck, M.D. (1994). Interactions of lipids with immune function I: Biochemical effects of dietary lipids on plasma membranes. J. Nutr. Biochem. 5, 466-478
2. Halliwell, B. and Gutteridge, J.M.C. (1989). Free Radicals in Biology and Medicine, 2nd ed. Clarendon Press, Oxford UK
3. Gutteridge, J.M.C. and Halliwell, B. (1994). Antioxidants in Nutrition, Health and Disease. Oxford University Press, Oxford UK
4. Wiseman, H. (1994). Tamoxifen: Molecular Basis of Use in Cancer Treatment and Prevention. John Wiley & Sons, Ltd., Chichester UK
5. Morrissey, P.A., Quinn, P.B., and Sheehy, P.J.A. (1994). Newer aspects of micronutrients in chronic disease: Vitamin E. Proc. Nutr. Soc. 53, 571-582
6. Wiseman, H. (1993). Vitamin D is a membrane antioxidant. Ability to inhibit iron-dependent lipid peroxidation in liposomes compared to cholesterol, ergosterol and tamoxifen and relevance to anticancer action. FEBS Lett. 326, 285-288
7. Thurnham, D.I. (1994). Newer aspects of micronutrients in chronic disease: β-carotene, Are we misreading the signals in risk groups? Some analogies with vitamin C. Proc. Nutr. Soc. 53, 557-569
8. Thompson, L.U. (1994). Antioxidants and hormone-mediated health benefits of whole grains. Crit. Rev. Food Sci. Nutr. 34, 473-497
9. Morton, M.S., Wilcox, G., Wahlqvist, M.L., and Griffiths, K. (1994). Determination of lignans and isoflavonoids in human female plasma following dietary supplementation. J. Endocrinol. 142, 251-259
10. Hendrich, S., Lee, K.W., Xu, X., Wang, H.J., and Murphy, P.A. (1994). Defining food components as new nutrients. J. Nutr. 124(Suppl), 1789s-1792s
11. Aldercreutz, H., Fotis, T., Watanabe, S., Lampe, J., Wahala, K., Makela, T., and Hase, T. (1994). Determination of lignans and isoflavonoids in plasma by isotope dilution gas chromatography-mass spectrometry. Cancer Detect. Prevent. 18, 259-271
12. Messina, M.J., Persky, V., Setchell, K.D., and Barnes, S. (1994). Soy intake and cancer risk: A review of the in vitro and in vivo data. Nutr. Cancer 21, 113-131
13. Esterbauer, H. (1993). Cytotoxicity and genotoxicity of lipid-oxidation products. Am. J. Clin. Nutr. 57(Suppl), 779s-786s
14. Halliwell, B. (1993). The role of oxygen radicals in human disease, with particular reference to the vascular system. Haemostasis 23(Suppl), 118-126
15. Halliwell, B. (1994). Free radicals and antioxidants: a personal view. Nutr. Rev. 52, 253-265
16. Halliwell, B. (1994). Free radicals, antioxidants and human disease: curiosity, cause or consequence? Lancet 344, 721-724
17. Diplock, A.T., Rice-Evans, C.A., and Burdon, R.H. (1994). Is there a significant role for lipid peroxidation in the causation of malignancy and for antioxidants in cancer prevention. Cancer Res. 54(Suppl), 1952s-1956s
18. Cerutti, P. (1994). Oxy-radicals and cancer. Lancet 344, 862-863
19. Esterbauer, H., Gebicki, J., Puhl, H., and Jurgens, G. (1992). The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Radical Biol. Med. 13, 341-390
20. Witzum, J.L. (1994). The oxidation hypothesis of atherosclerosis. Lancet 344, 792-795
21. Parthasarathy, S. and Santanam, N. (1994). Mechanisms of oxidation, antioxidants and atherosclerosis. Curr. Opinion Lipidol. 5, 371-375
22. Holvoet, P. and Collen, D. (1994). Oxidized lipoproteins in atherosclerosis and thrombosis. FASEB J. 15, 1279-1284
23. O'Keefe, J.H. Jr, Lavie, C.J. Jr., and McCallister, B.D. (1995). Insights into the pathogenesis and prevention of coronary artery disease. Mayo Clinic Proc. 70, 69-79
24. Gurr M.I. and Harwood J.L. (1991). Lipid Biochemistry: An Introduction, Fourth Edition. Chapman and Hall, London, UK
25. Zachowski, A. (1993). Phospholipids in animal eukaryotic membranes: transverse asymmetry and movement. Biochem. J. 294, 1-14
26. Williamson, P. and Schlegel, R.A. (1994). Back and forth: the regulation and function of transbilayer phospholipid movement in eukaryotic cells Mol. Membrane Biol. 11, 199-216
27. New, R.R.C. (1992). Liposomes: A Practical Approach, IRL Press, Oxford, UK
28. Berlin, E., Bhathena, S.J., Judd, J.T., Nair, P.P., Peters, R.C., Bhagavan, H.N., Ballard-Barbash, R., and Taylor, P.R. (1992). Effects of omega-3 fatty acid and vitamin E supplementation on erythrocyte membrane fluidity, tocopherols, insulin binding, and lipid composition in adult men. J. Nutr. Biochem. 3, 392-400
29. Berlin, E., Bhathena, S.J., Judd, J.J., Clevidence, B.A., and Peters, R.C. (1994). Human erythrocyte membrane fluidity and insulin binding are independent of dietary trans fatty acids. J. Nutr. Biochem. 5, 591-598
30. Barzanti, V., Pregnolato, P., Maranesi, M., Bosi, I., Baracca, A., Solaini, G., and Turchetto, E. (1995). Effect of dietary oils containing graded amounts of 18:3 n-6 and 18:4 n-3 on cell plasma membranes. J. Nutr. Biochem. 6, 21-26
31. Darley-Usmar, V., Wiseman, H., and Halliwell, B. (1995). Nitric oxide and oxygen radicals: A question of balance. FEBS Lett., 36(9), 131-135
32. Dean, R.T., Gieseg, S., and Davies, M.J. (1993). Reactive species and their accumulation on radical-damaged proteins. Trends Biochem. Sci. 18, 437-441
33. Stadtman, E.R. (1993). Oxidation of free amino acids and amino acid residues in proteins by radiolysis and by metal-catalysed reactions. Ann. Rev. Biochem. 62, 797-821
34. Oliver, C.N., Ahn, B-W, Moerman, E.J., Goldstein, S., and Stadtman, E.R. (1987). Age-related changes in oxidized proteins. J. Biol. Chem. 262, 5488-5491
35. Halliwell, B. (1990). How to characterize a biological antioxidant. Free Radical Res. Commun. 9, 1-32
36. Ames, B.N. (1989). Endogenous oxidative DNA damage, aging and cancer. Free Radical Res. Commun. 7, 121-128
37. Salganik, R.I., Solovyova, N.A., Dikalov, S.I. Grishaeva, O.N., Semenova, L.A., and Popovsky, A.V. (1994). Inherited enhancement of hydroxyl radical generation and lipid peroxidation in the S strain rats results in DNA rearrangements, degenerative diseases and premature aging. Biochem. Biophys. Res. Commun. 199, 726-733
38. Wiseman, H. and Halliwell, B. (1995). Damage to DNA by reactive oxygen and nitrogen species: Role in inflammatory disease and progression to cancer. Biochem. J., in press
39. Girelli, D., Olivieri, O., Stanzial, A.M., Guarini, P., Trevisan, M.T., Bassi, A., and Corrocher, R. (1994). Factors affecting the thiobarbituric acid test as index of red blood cell susceptibility to lipid peroxidation: A multivariate analysis. Clin. Chim. Acta 227, 45-57
40. Chatterjee, S.N. and Agarwal, S. (1988). Liposomes as a membrane model for study of lipid peroxidation. Free Radical Biol. Med. 4, 51-72
41. Halliwell, B. and Chirico, S. (1993). Lipid peroxidation: Its mechanism, measurement and significance. Am. J. Clin. Nutr. 57, 15S-25S
42. Saito, M. and Nakatsugawa, K. (1994). Increased susceptibility of liver to lipid peroxidation after ingestion of a high fish oil diet. Int. J. Vit. Miner. Res. 64, 144-151
43. Reddy, A.C.P. and Lokesh, B.R. (1994). Alterations in lipid peroxides in rat liver by dietary n-3 fatty acids: modulation of antioxidant enzymes by curcumin, eugenol, and vitamin E. J. Nutr. Biochem. 5, 181-188
44. Wolff, S.P. and Dean, R.T. (1987). Glucose autoxidation and protein modification: The potential role of "autoxidative glycosylation" in diabetes. Biochem. J. 245, 243-250
45. Kagan, V.E., Serbinova, E.A., Bakalova, R.A., Stoytchev, T.S., Erin, A.N., Prilipko, L.L., and Evstigneeva, R.P. (1990). Mechanisms of stabilization of biomembranes by alpha-tocopherol. Biochem. Pharmacol. 40, 2403-2413
46. Kaneko, T., Kaji, K., and Matsuo, M. (1994). Protection of linoleic acid and hydroperoxide-induced cytotoxicity by phenolic antioxidants Free Radical Biol. Med. 16, 405-409
47. Pellett, L.J., Anderson, H.J., Chen, H., and Tappel, A.L. (1994). β-carotene alters vitamin E protection against heme protein oxidation and lipid peroxidation in chicken liver slices. J. Nutr. Biochem. 5, 479-484
48. Nordmann, R. (1994). Alcohol and antioxidant systems. Alcohol Alcoholism 29, 513-522
49. Frei, B., Kim, M.C., and Ames, B.N. (1990). Ubiquinol-10 is an effective lipid-souble antioxidant at physiological concentrations. Proc. Natl. Acad. Sci. USA 87, 4879-4883
50. Barja, G., Lopez-Torres, M., Perez-Campo, R., Rojas, C., Cadenas, S., Prat, J., and Pamplona, R. (1994). Dietary vitamin C decreases endogenous protein oxidative damage, malondialdehyde, and lipid peroxidation and maintains fatty acid unsaturation in the guinea pig liver. Free Radical Biol Med. 17, 105-115
51. Burton, G.W. and Ingold, K.U. (1984). β-carotene: An unusual type of lipid antioxidant. Science 224, 569-573
52. Allard, J.P., Royall, D., Kurian, R., Muggli, R., and Jeejeebhoy, K.N. (1994). Effects of β-carotene supplementation on lipid peroxidation in humans. Am. J. Clin. Nutr. 59, 884-890
53. Anderson, J.J.B, and Toverud, S.U. (1994). Diet and vitamin D: A review with an emphasis on human function. J. Nutr. Biochem. 5, 58-65
54. Laughton, M.J., Halliwell, B., Evans, P.J., and Hoult, J.R. (1989). Antioxidant and pro-oxidant actions of the plant phenolics quercetin, gossypol and myricetin. Effects on lipid peroxidation, hydroxyl radical generation and bleomycin-dependent damage to DNA. Biochem. Pharmacol. 38, 2849-2865
55. Vinson, J.A. and Hontz, B.A. (1995). Phenol antioxidant index: comparative effectiveness of red and white wines. J. Agric. Food Sci. 43, 401-403
56. Sanz, M.J., Ferrandiz, M.L., Cejudo, M., Terencio, M.C., Gil, B., Bustos, G., Ubeda, A., Gunasegaran, R., and Alcaraz, M.J. (1994). Influence of a series of natural flavonoids on free radical generating systems and oxidative stress. Xenobiotica 24, 689-699
57. Shimoi, K., Masuda, S., Furugori, M., and Kinae, N. (1994). Radioprotective effect of antioxidative flavonoids in gamma-ray irradiated mice. Carcinogenesis 15, 2669-2672
58. Jha, H.C., von Recklinghausen, G., and Zilliken, F. (1985). Inhibition of in vitro microsomal lipid peroxidation by isoflavonoids. Biochem. Pharmacol. 34, 1367-1369
59. Sugioka, K., Shimosegawa, M., and Nakano, M. (1987). Estrogens as natural antioxidants of membrane phospholipid peroxidation. FEBS Lett. 210, 192-194
60. Wiseman, H., Laughton, M.J., Arnstein, H.R.V., Cannon, M., and Halliwell, B. (1990). The antioxidant action of tamoxifen and its metabolites. Inhibition of lipid peroxidation. FEBS Lett. 263, 192-194
61. Wiseman, H. (1994). The antioxidant action of a pure antioestrogen. Ability to inhibit lipid peroxidation compared to tamoxifen and 17 β-oestradiol and relevance to its anticancer potential. Biochem. Pharmacol. 47, 493-498
62. Ruiz-Larrea, M.B., Leal, A.M., Liza, M., Lacort, M., and de Groot, H. (1994). Antioxidant effects of estradiol and 2-hydroxyestradiol on iron-induced lipid peroxidation in rat liver microsomes. Steroids 59, 383-388
63. Lacort, M., Leal, A.M., Liza, M., Martin, C., Martinez, R., and Ruiz-Larrea, M.B. (1995). Protective effect of estrogens and catechol estrogens against peroxidative membrane damage in vitro. Lipids 30, 141-146
64. Burri, J., Graf, M., Lambelet, P., and Loliger, J. (1989). Vanillin: More than a flavouring agent-a potent antioxidant. J. Sci. Food Agric. 48, 49-56
65. Aruoma, O.I., Halliwell, B., Aesschback, R., and Loligers, J. (1992). Antioxidant and pro-oxidant properties of active rosemary constituents: carnosol and carnosic acid. Xenobiotica 22, 257-268
66. Stadler, R.H., Turesky, R.J., Muller, O., Markovic, J., and Leong-Morgenthaler, P.M. (1994). The inhibitory effects of coffee on radical-mediated oxidation and mutagenicity. Mutat. Res. 308, 177-190
67. Imai, J., Ide, N., Nagae, S., Moriguchi, T., Matsura, H., and Itakura, Y. (1994). Antioxidant and radical scavenging effects of aged garlic extract and its constituents. Planta Medico 60, 417-420
68. Xu, Z. and Bray, T.M. (1994). Electron spin resonance spin trapping studies of the effects of dietary zinc deficiency on free radical production in vitro and in vivo under acute oxidative stress. J. Nutr. Biochem. 5, 490-494
69. Michiels, C., Raes, M., Toussaint, O., and Remade, J. (1994). Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell against oxidative stress. Free Radical Biol. Med 17, 235-248
70. White, A.C., Thannickal, V.J., and Fanburg, B.L. (1994). Glutathione deficiency in human disease. J. Nutr. Biochem. 5, 218-226
71. Zhang, D., Yasuda, T., Yu, Y., and Okada, S. (1994) Physiocochemical damage to liposomal membrane induced by iron-or copper-mediated lipid peroxidation. Acta Medico Okayama 48, 131-136
72. Strain, J.J. (1994). Newer aspects of micronutrients in chronic disease: copper. Proc. Nutr. Soc. 53, 583-598
73. Costanzo, L.L., De Guidi, G., Giuffrida, S., Condorelli, G. and Pappalardo, G. (1995). Antioxidant effect of copper(II) on photosensitized lipid peroxidation. J. Inorg. Biochem. 57, 115-125
74. Dutta-Roy, A.K., Gordon, M.J., Campbell, P.M., Duthie, G.G., and James, W.P.T. (1994). Vitamin E requirements, transport, and metabolism: Role of α-tocopherol-binding proteins. J. Nutr. Biochem. 5, 562-570
75. Dmitriev, L.F., Ivanova, M.V., and Lankin, V.Z. (1994). Interaction of tocopherol with peroxyl radicals does not lead to the formation of lipid hydroperoxides in liposomes. Chem. Phys. Lipids 69, 35-39
76. Buettner, G.R. (1993). The pecking order of free radicals and antioxidants: lipid peroxidation, α-tocopherol and ascorbate. Arch. Biochem. Biophys. 300, 535-543
77. Beyer, R.E. (1994). The role of ascorbate in antioxidant protection of biomembranes: interaction with vitamin E and coenzyme Q. J. Bioenerg. Biomemb. 26, 349-358
78. Kagan, V., Serbinova, E., and Packer, L. (1990). Antioxidant effects of ubiquinones in microsomes and mitochondria are mediated by tocopherol recycling. Biochem. Biophys. Res. Commun. 169, 851-857
79. Bisby, R.H. (1990). Interactions of vitamin E with free radicals and membranes. Free Rad. Res Commun. 8, 299-306
80. Clarke, R., van den Berg, H.W., and Murphy, R.F. (1990). Reduction of the membrane fluidity of human breast cancer cells by tamoxifen and 17β-estradiol. J. Natl. Cancer Inst. 82, 1702-1705
81. Wiseman, H., Quinn, P., and Halliwell, B. (1993). Tamoxifen and related compounds decrease membrane fluidity in liposomes. Mechanism for the antioxidant action of tamoxifen and relevance to its anticancer and cardioprotective actions? FEBS Lett. 330, 53-56
82. Viret, J., Daveloose, D., and Leterrier, F. (1990). Modulation of the activity of functional membrane proteins by the lipid bilayer fluidity. In Membrane Transport and Information Storage (R.C. Aloia, C.C. Curtain, and L.M. Gordon, eds.), p. 239-253, Wiley-Liss, New York, NY USA
83. van Ginkel, G. and Sevanian, A. (1994). Lipid peroxidation-induced membrane structural alterations. Meth. Enzymol. 233, 273-288
84. Biagi, P.L., Bordoni, A., Hrelia, S., Celadon, M., and Turchetto, E (1993). The effect of dietary polyphosphatidylcholine on microsomal delta-6-desaturase activity, fatty acid composition and microviscosity in rat liver under oxidative stress. J. Nutr. Biochem. 4. 690-694
85. Houslay, M.D. (1985). Regulation of adenylate cyclase (EC4.6.1.1.) activity by its lipid environment. Proc. Nutr. Soc. 44. 157-165
86. Jansson, C., Harmala, A.S., Torvola, D.M., and Slotte, J.P. (1993) Effects of the phospholipid environment in the plasma membrane on receptor interaction with the adenylyl cyclase complex of intact cells. Biochim. Biophys. Acta 1145, 311-319
87. Gschwent, M., Kittstein, W., and Marks, F. (1991). Protein kinase C activation by phorbol esters: do cysteine-rich regions and pseudosubstrate motifs play as role? Trends Biochem. Sci. 16, 167-169
88. Burns, D.J. and Bell, R.M. (1992). Lipid regulation of protein kinase C. In Protein kinase C: Current Concepts and Future Prospectives (D.S. Lester and R.M. Epand, eds.), p. 25-40, Ellis Horwood, Chichester, UK
89. Kagan, V.E., Bakalova, R.A., Koynova, G.M., Tyurin, V.A., Serbinova, E.A., Petkov, V.V., Petkov, V.D., Staneva, D.S., and Packer, L. (1992). Antioxidant protection of the brain against oxidative stress. In Free Radicals in the Brain: Aging, Neurological, and Mental Disorders (L. Packer, L. Prilipko, and Y. Christen. eds.), p. 49-61, Springer-Verlag, Berlin
90. Kolesnick, R. and Golde, D.W. (1994). The spingomyelin pathway in tumor necrosis factor and interleukin-1 signaling. Cell 77, 325-328
91. Hubbard, S.R., Wei, L., Ellis, L., and Hendrickson, W.A. (1994). Crystal structure of the tyrosine kinase domain of the human insulin receptor. Nature 372, 746-753
92. McCallum, C.D. and Epand, R.M. (1995). Insulin receptor autophosphorylation and signalling is altered by modulation of membrane physical properties. Biochemistry 34, 1815-1824
93. Bhathena, S.J., Berlin, E., Revett, K., and Ommaya, A.E.K. (1986). Modulation of erythrocyte insulin receptors by dietary lipid. Ann. N.Y. Acad. Sci. 463, 165-167
94. Barnard, D.E. Sampugna, J., Berlin, E., Bhathena, S.J., and Knapka, J.J. (1990). Dietary trans fatty acids modulate erythrocyte membrane fatty acyl composition and insulin binding in monkeys. J. Nutr. Biochem. 1, 190-195
95. Ohyashiki, T., Kumada, Y., Hatanaka, N., and Matsui, K. (1994). Oxygen radical-induced inhibition of alkaline phosphatase activity in reconstituted membranes. Arch. Biochem. Biophys. 313, 310-317
96. Ohyashiki, T., Sakata, N., and Matsui, K. (1994). Changes in SH reactivity of the protein in porcine intestinal brush-border membranes associated with lipid peroxidation. J. Biochem. 115, 224-229
97. Holting, T., Siperstein, A.E., Clark, O.H., and Duh, Q.Y. (1995). Epidermal growth factor (EGF)-and transforming growth factor α-stimulated invasion and growth of follicular thyroid cancer cells can be blocked by antagonism to the EGF receptor and tyrosine kinase in vitro. Eur. J. Endocrinol. 132, 229-235
98. Gamou, S. and Shimizu, N. (1995). Hydrogen peroxide preferentially enhances the tyrosine phosphorylation of epidermal growth factor receptor. FEBS Lett. 357, 161-164
99. Dumont, I.E., Jauniaux, J.C., and Rogers, P.P. (1989). The cyclic AMP-mediated stimulation of cell proliferation. Trends Biochem. Sci. 14, 67-71
100. Hertog, M.G.L., Hollman, P.C., Katan, M.B., and Kromhout, D. (1993). Intakes of potentially anticardinogenic flavonoids and their determinants in adults in The Netherlands. Nutr. Cancer 20, 21-29
101. Collins, A., Duthie, S., and Ross., M. (1994). Micronutrients and oxidative stress in the aetiology of cancer. Proc. Nutr. Soc. 53, 67-75
102. Pagliacci, M.C., Smacchia, M., Migliorati, G., Riccardi, C., and Nicoletti, I. (1994). Growth-inhibitory effects of the natural phytooestrogen genistein in MCF-7 human breast cancer cells. Eur. J. Cancer 30A, 1675-1682
103. Scholar, E.M. and Toews, M.L. (1994). Inhibition of invasion of murine mammary carcinoma cells by the tyrosine kinase inhibitor genistein. Cancer Lett. 87, 159-162
104. Lipkin, M. and Boone, C.W. (1991). Calcium, vitamin D and cancer. Cancer Res. 51, 3069-3070
105. Colston, K.W., MacKay, A.G., James, S.Y., Binderup, L., Chander, S., and Coombes, C. (1992). EB1089: A new vitamin D analogue that inhibits the growth of breast cancer cell in vivo and in vitro. Biochem. Pharmacol. 44, 2273-2280
106. Hunter, D.J., Manson, J.E., Colditz, G.A., Stampfer, M.J., Rosner, B., Hennekens, C.H., Speizer, F.E., and Willet, W.C. (1993). A prospective study of the intake of vitamins C, E and A and the risk of breast cancer. New Engl. J. Med. 329, 234-240
107. Pasman, P.C. and Schouten, H.C. (1993). Multidrug resistance mediated by P-glycoprotein in haematological malignancies. Netherlands J. Med 42, 218-231
108. Leonessa, F., Jacobson, M., Boyle, B., Lippmann, J., McGarvey, M., and Clarke, R. (1994). Effect of tamoxifen on the multidrugresistant phenotype in human breast cancer cells: isobologram, drug accumulation, and Mr 170,000 glycoprotein (gp170) binding studies. Cancer Res. 54, 441-447
109. Kayyali, R., Marriott, C., and Wiseman, H. (1994). Tamoxifen decreases drug efflux from liposomes. Relevance to its ability to reverse multidrug resistance in cancer cells. FEBS Lett. 344, 221-224
110. Takeda, Y., Nishio, K., and Saijo, N. (1994). Reversal of multidrug resistance by tyrosine-kinase inhibitors in a non-P-glycoprotein-mediated multidrug-resistant cell line. Int. J. Cancer 57, 229-239
111. Burns, C.P. and Spector, A.A. (1994). Biochemical effects of lipids on cancer therapy. J. Nutr. Biochem. 5, 114-123
112. Wagner, B.A., Beuttner, G.R., and Burns, C.P. (1993). Increased generation of lipid-derived and ascorbate free radicals by L1210 cells exposed to the ether lipid edelfosine. Cancer Res. 53, 711-713
113. Wagner, B.A., Beuttner, G.R., and Burns, C.P. (1992). Membrane peroxidative damage by the ether lipid class of antineoplastic agents. Cancer Res. 52, 6045-6051
114. Madhavi, N. and Das, U.N. (1994). Effect of n-6 and n-3 fatty acids on the survival of vincristine sensitive and resistant human cervical carcinoma cells in vitro. Cancer Lett. 84, 31-41
115. Cheeseman, K.H. (1993). Lipid peroxidation and cancer. In DNA and Free Radicals (B. Halliwell and O.I. Aruoma eds.), p. 109-144, Ellis Horwood, Chichester, UK
116. Goldring, C.E.P., Rice-Evans, C.A., Burdon, R.H., Rao, R., Haq, I., and Diplock, A.T. (1993). α-tocopherol uptake and its influence on cell proliferation and lipid peroxidation in transformed and non-transformed baby hamster kidney cells. Arch. Biochem. Biophys. 303, 429-435
117. Boyd, N.F. and McGuire, V. (1991). The possible role of lipid peroxidation in breast cancer risk. Free Radical Biol. Med. 10, 185-190
118. Rosin, M.P. Anwar, W.A., and Ward, A.J. (1994). Inflammation, chromosomal instability and cancer: the Schistosomiasis model. Cancer Res. 54(Suppl), 1929s-1933s
119. Shigenaga, M.K., Hagen, T.M., and Ames, B.N. (1994). Oxidative damage and mitochondrial decay in aging. Proc. Natl. Acad. Sci. USA 91, 10771-10778
120. Jenner, P. (1994). Oxidative damage in neurodegenerative disease Lancet 344, 796-798
121. Tritschler, H.J., Packer, L., and Medori, R. (1994). Oxidative stress and mitochondrial dysfunction in neurodegeneration. Biochem. Mol. Biol. Int. 34, 169-181
122. Hruszkewycz, A.M. (1992). Lipid peroxidation and mtDNA degeneration. A hypothesis. Mutation Res. 275, 243-248
123. Arnheim, N. and Cortopassi, G. (1992) Deleterious mitochondrial DNA mutations accumulate in aging human tissues. Mutation Res. 275, 169-180
124. Mecocci, P., MacGarvey, U, and Beal, M.F. (1995). Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease. Ann. Neurol. 36, 747-751
125. Sohal, R.S., Ku, H-H., Agarwal, S., Forster, M.J., and Lal, H. (1994). Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging in response to food restriction in the mouse. Mech. Ageing Dev. 74, 121-133
126. Sandhir, R., Julka, D., and Gill, K.D. (1994). Lipoperoxidative damage on lead exposure in rat brain and its implications on membrane bound enzymes. Pharmacol. Toxicol. 74, 66-71
127. Olivieri, O., Stanzial, A.M., Girelli, D., Trevisan, M.T., Guarini, P., Terzi, M., Caffi, S., Fontana, F., Casaril, M., Ferrari, S., and Corrocher, R. (1994). Selenium status, fatty acids, vitamins A and E and aging: The Nove study. Am. J. Clin. Nutr. 60, 510-517
128. Hightower, K.R., McCready, J.P., and Borchman, D. (1994). Membrane damage in UV-irradiated lenses. Photochem. Photobiol. 59, 485-490
129. Barrett, B.M., Sowell, A., Gunter, E., and Wang, M. (1994). Potential role of ascorbic acid and β-carotene in the prevention of preterm rupture of fetal membranes. Int. J. Vitamin Miner. Res. 64, 192-197
130. Favier, A., Sappey, C., Leclerc, P., Faure, P., and Micoud, M. (1994). Antioxidant status and lipid peroxidation in patients infected with HIV. Chem. Biol. Int. 91, 165-180
131. Gramlich, L.M. and Mascioli, E.A. (1995). Nutrition and HIV infection. J. Nutr. Biochem. 6, 2-11
132. Rice-Evans, C.A. and Bruckdorfer, K.R. (1992). Free radicals, lipoproteins and cardiovascular dysfunction. Molec. Aspects Med. 13, 1-111
133. Ferretti, G., Alleva, R., Taus, M., Simonetti, O., Cinti, B., Offidani, A.M., Bossi, G., and Curatola, G. (1994). Abnormalities of plasma lipoprotein composition and fluidity in psoriasis. Acta DermatoVenereologica 74, 171-175
134. Nyyssonen, K., Porkkala, E., Salonen, R., Korpela, H., and Salonen, J.T. (1994). Increase in oxidation resistance of atherogenic serum lipoproteins following antioxidant supplementation: A randomized double-blind placebo-controlled clinical trial. Eur. J. Clin. Nutr. 48, 633-642
135. Huffman, R.M. and Garewall, H.S. (1995). Antioxidants and the prevention of coronary heart disease. Arch. Int.Med. 155, 241-246
136. Smith, C., Mitchinson, M., Aruoma, O.I. and Halliwell, B. (1992). Stimulation of lipid peroxidation and hydroxyl radical generation by the contents of human atherosclerotic lesions. Biochem. J. 286, 901-905
137. 2+-stimulated oxidation of low-density lipoprotein. Arch. Biochem. Biophys. 315, 244-254
138. Parfitt, V.J., Rubba, P., Bolton, C., Marotta, G., Hartog, M., and Mancini, M. (1994). A comparison of antioxidant status and free radical peroxidation of plasma lipoproteins in healthy young persons from Naples and Bristol. Eur. Heart J. 15, 871-876
139. Croft, K.D., Williams, P., Dimmitt, S., Abu-Amsha, R., and Beilin, L.J. (1995). Oxidation of low-density lipoproteins: Effect of antioxidant content, fatty acid composition and intrinsic phospholipase activity on susceptibility to metal ion-induced oxidation. Biochim. Biophys. Acta 1254, 250-256
140. Visioli, F. and Galli, C. (1994). Oleuropein protects low density lipoprotein from oxidation. Life Sci. 55, 1965-1971
141. Beare-Rogers, J. (1994). Controversies in lipid nutrition. Chem. Industry 20 February, 131-134
142. Pollard, L., Oakely, F.R., and Sanders, T.A.B. (1994). Influence of dietary n-3 fatty acids on susceptibility of LDL to oxidation in man. Proc. Nutr. Sec. 53, 78A
143. Manning, J.M., Gebre, A.K., Edwards, I.J., Wagner, W.D., Rudel, L.L., and Parks, J.S. (1994). Dietary polyunsaturated fat decreases interaction between low density lipoproteins and arterial proteoglycans. Lipids 29, 635-641
144. Suzukawa, M., Ishikawa, T., Yoshida, H., Hosoai, K., NIshio, E., Yamashita, T., Nakamura, H., Hashizume, N., and Susuki, K. (1994). Effects of alcohol consumption on antioxidant content and susceptibility of low density lipoprotein to oxidative modification. J. Am. College Nutr. 13, 237-242
145. Frankel, E.N., Kanner, J., German, J.B., Parks, E., and Kinsella. J.E. (1993). Inhibition of oxidation of human low-density lipoproteins by phenolic substances in red wine. Lancet 341, 454-457
146. Furhrman, B., Lavy, A., and Aviram, M. (1995). Consumption of red wine with meals reduces the susceptibility of human plasma and low-density lipoprotein to lipid peroxidation. Am. J. Clin. Nutr. 61, 549-554
147. Whitehead, T.P., Robinson, D., Allaway, S., Syms, J., and Hale, A. (1995). Effect of red wine ingestion on the antioxidant capacity of serum. Clin. Chem. 41, 32-35
148. Waterhouse, A.L. (1995). Wine and heart disease. Chem. Industry 1 May, 338-341
149. Hertog, M.G.L., Feskens, E.J.M., Hollman, P.C.H., Katan, M.B., and Kromhout, D. (1993). Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen Elderly Study. Lancet 342, 1007-1011
150. Frankel, E.N., Waterhouse, A.L., and Kinsella, J.E. (1993). Inhibition of human LDL oxidation by resveratrol. Lancet 341, 1103-1104
151. Laranjinha, J.A., Almeida, L.M., and Madeira, V.M. (1994). Reactivity of dietary phenolic acids with peroxyl radicals: antioxidant activity upon low density lipoprotein peroxidation. Biochem. Pharmacol. 48, 487-494
152. Huber, L.A., Scheffler, E., Poll, T., Ziegler, R., and Dresel, H.A. (1990). 17 Beta-estradiol inhibits LDL oxidation and cholesteryl ester formation in cultured macrophages. Free Rad. Res. Commun. 8, 167-173
153. Rifici, V.A. and Khachadurian, A.K. (1992). The inhibition of low-density lipoprotein oxidation by 17-β estradiol. Metabolism 41, 1110-1114
154. Wiseman, H., Paganga, G., Rice-Evans, C., and Halliwell, B. (1993). Protective actions of tamoxifen and 4-hydroxytamoxifen against oxidative damage to human low-density lipoproteins. A mechanism accounting for the cardioprotective action of tamoxifen? Biochem. J. 292, 635-638
155. Sack, M.N., Rader, D.J., and Cannon, R.O. (1994). Oestrogen and inhibition of oxidation of low-density lipoproteins in postmenopausal women. Lancet 343, 269-270
156. Popov, I., Blumstein, A., and Lewin, G. (1994). Antioxidant effects of aqueous garlic extract. 1st communication: Direct detection using the photochemiluminescence. Arzneimittel-Forschung 44, 602-604
157. +)-initiated oxidation of low density lipoproteins. Arzneimittel-Forschung 44, 604-607
158. Imai, K. and Nakachi, K. (1995). Cross-sectional study of effects of drinking green tea on cardiovascular and liver diseases. Br. Med. J. 310, 693-696
159. Carson, C.A., Caggiula, A.W., Meilahn, E.N., Matthews, K.A., and Kuller, L.H. (1994). Coffee consumption: relationship to blood lipids in middle-aged women. Int. J. Epidemiol. 23, 523-527
160. Judd, J.T., Clevidence, B.A., Museing, R.A., Wittes, J., Sunkin, M.E., and Podczasy, J.J. (1994). Dietary trans fatty acids-effects on plasma lipids and lipoproteins. Am. J. Clin. Nutr. 59, 861-868
161. Katan, M.B., Zock, P.L., and Mensink, R.P. (1994). Effects of fats and fatty acids on blood lipids in humans: an overview. Am. J. Clin Nutr. 60(Suppl), 1017S-1022S
162. van Poppel, G., Hospers, J., Buytenhek, R., and Princen, H.M. (1994). No effect of beta-carotene supplementation on plasma lipoproteins in healthy smokers. Am. J. Clin. Nutr. 60, 730-734
163. Haffner, S.M. and Valdez, R.A. (1995). Endogenous sex hormones: impact on lipids lipoproteins, and insulin. Am. J. Med. 98, 408-475
164. Seydel, J.K., Coats, E.A., Cordes, H.P., and Wiese, M. (1994). Drug membrane interaction and the importance for drug transport, distribution, accumulation, efficacy and resistance. Archiv der Pharmazie 327, 601-610
165. Block, G., Patterson, B., and Subar, A. (1992). Fruit, vegetables and cancer prevention: A review of the epidemiological evidence. Nutr. Cancer 18, 1-29