Hybrid angiogenesis inhibitors: Synthesis and biological evaluation of bifunctional compounds based on 1-deoxynojirimycin and aryl-1,2,3-triazoles

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 3, 2008, Pages 954-958

  Zhou, Ying ^a   Zhao, Yunxue ^a   O' Boyle, Kathy M ^a   Murphy, Paul V ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

1 Deoxynojirimycin; Alpha glucosidase; Angiogenesis; Aryl 1,2,3 triazole; Bifunctional compound; Hybrid; Inhibitor; Methionine aminopeptidase

Indexed keywords

1 DEOXYNOJIRIMYCIN; ANGIOGENESIS INHIBITOR; FUMAGILLIN; METHIONYL AMINOPEPTIDASE 2; OLIGOSACCHARIDE; OVALICIN; PPI 2458; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ANGIOGENESIS; ARTICLE; CELL SURFACE; CONTROLLED STUDY; CYCLOADDITION; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; HUMAN; HUMAN CELL;

1-DEOXYNOJIRIMYCIN; ALPHA-GLUCOSIDASES; AMINOPEPTIDASES; ANGIOGENESIS INHIBITORS; ANIMALS; ENDOTHELIAL CELLS; HUMANS; METALLOENDOPEPTIDASES; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; TRIAZOLES;

EID: 38849143209     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.12.034     Document Type: Article

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