Identification of novel inhibitors of fibroblast growth factor (FGF-2) binding to heparin and endothelial cell survival from a structurally diverse carbohybrid library

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 22, 2002, Pages 3287-3290

  Murphy, Paul V ^a   Pitt, Nigel ^a   O'Brien, Alan ^a   Enright, Philomena M ^a   Dunne, Amanda ^a   Wilson, Stephen J ^a   Duane, Rhona M ^a   O'Boyle, Kathy M ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; FIBROBLAST GROWTH FACTOR 2; GLUCURONIC ACID; HEPARIN; PROTEOHEPARAN SULFATE; ANGIOGENESIS INHIBITOR;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CONJUGATE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; NONHUMAN; PROTEIN PROTEIN INTERACTION; ANIMAL; AORTA; CATTLE; CHEMISTRY; COMBINATORIAL CHEMISTRY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PROTEIN BINDING; STRUCTURE ACTIVITY RELATION; VASCULAR ENDOTHELIUM;

ANGIOGENESIS INHIBITORS; ANIMALS; AORTA; CATTLE; CELL SURVIVAL; COMBINATORIAL CHEMISTRY TECHNIQUES; ENDOTHELIUM, VASCULAR; FIBROBLAST GROWTH FACTOR 2; GLUCURONIC ACID; HEPARIN; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037131770     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00700-X     Document Type: Article

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