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Volumn 2, Issue 12, 2007, Pages 3063-3073

Subtractive single-chain antibody (Scfv) phagedisplay: Tailoring phage-display for high specificity against function-specific conformations of cell membrane molecules

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; EPITOPE; IMMUNOGLOBULIN FRAGMENT; LIGAND; PEPTIDE LIBRARY;

EID: 38849132141     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2007.455     Document Type: Article
Times cited : (69)

References (28)
  • 1
    • 0025835310 scopus 로고
    • Making antibody fragments using phage display libraries
    • Clackson, T., Hoogenboom, H.R., Griffiths, A.D. & Winter, G. Making antibody fragments using phage display libraries. Nature 352, 624-628 (1991).
    • (1991) Nature , vol.352 , pp. 624-628
    • Clackson, T.1    Hoogenboom, H.R.2    Griffiths, A.D.3    Winter, G.4
  • 3
    • 18244407799 scopus 로고    scopus 로고
    • Steps toward mapping the human vasculature by phage display
    • Arap, W. et al. Steps toward mapping the human vasculature by phage display. Nat. Med. 8, 121-127 (2002).
    • (2002) Nat. Med , vol.8 , pp. 121-127
    • Arap, W.1
  • 4
    • 9444277172 scopus 로고    scopus 로고
    • Single-chain antibodies forthe conformation-specific blockade of activated platelet integrin alphaIIbbeta3 designed by subtractive selection from naive human phage libraries
    • Schwarz, M. etal. Single-chain antibodies forthe conformation-specific blockade of activated platelet integrin alphaIIbbeta3 designed by subtractive selection from naive human phage libraries. FASEB J. 1704-1706 (2004).
    • (2004) FASEB J , pp. 1704-1706
    • Schwarz, M.1
  • 5
    • 34147152321 scopus 로고    scopus 로고
    • Generation of activation-specific human anti-alphaM/beta2 single-chain antibodies as potential diagnostic tools and therapeutic agents
    • Eisenhardt, S.U. etal. Generation of activation-specific human anti-alphaM/beta2 single-chain antibodies as potential diagnostic tools and therapeutic agents. Blood 109, 3521-3528 (2007).
    • (2007) Blood , vol.109 , pp. 3521-3528
    • Eisenhardt, S.U.1
  • 6
    • 33746234764 scopus 로고    scopus 로고
    • Conformation-specific blockade of the integrin GPIIb/IIIa: A novel antiplatelet strategy that selectively targets activated platelets
    • Schwarz, M. et al. Conformation-specific blockade of the integrin GPIIb/IIIa: a novel antiplatelet strategy that selectively targets activated platelets. Circ. Res. 99, 25-33 (2006).
    • (2006) Circ. Res , vol.99 , pp. 25-33
    • Schwarz, M.1
  • 7
    • 14744287360 scopus 로고
    • Targeting recombinant antibodies to the surface of Escherichia coli: Fusion to a peptidoglycan associated lipoprotein
    • Fuchs, P., Breitling, F., Dubel, S., Seehaus, T. & Little, M. Targeting recombinant antibodies to the surface of Escherichia coli: fusion to a peptidoglycan associated lipoprotein. Biotechnology 9, 1369-1372 (1991).
    • (1991) Biotechnology , vol.9 , pp. 1369-1372
    • Fuchs, P.1    Breitling, F.2    Dubel, S.3    Seehaus, T.4    Little, M.5
  • 8
    • 33847634290 scopus 로고    scopus 로고
    • Ribosome display: Selecting and evolving proteins in vitro that specifically bind to a target
    • Zahnd, C., Amstutz, P. & Pluckthun, A. Ribosome display: selecting and evolving proteins in vitro that specifically bind to a target. Nat. Methods 4, 269-279 (2007).
    • (2007) Nat. Methods , vol.4 , pp. 269-279
    • Zahnd, C.1    Amstutz, P.2    Pluckthun, A.3
  • 9
    • 0030817279 scopus 로고    scopus 로고
    • RNA-peptide fusions for the in vitro selection of peptides and proteins
    • Roberts, R.W. & Szostak, J.W. RNA-peptide fusions for the in vitro selection of peptides and proteins. Proc. Natl. Acad. Sci. USA 94, 12297-12302 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12297-12302
    • Roberts, R.W.1    Szostak, J.W.2
  • 10
    • 0030994634 scopus 로고    scopus 로고
    • Yeast surface display for screening combinatorial polypeptide libraries
    • Boder, E.T. & Wittrup, K.D. Yeast surface display for screening combinatorial polypeptide libraries. Nat. Biotechnol. 15, 553-557 (1997).
    • (1997) Nat. Biotechnol , vol.15 , pp. 553-557
    • Boder, E.T.1    Wittrup, K.D.2
  • 11
    • 0021818675 scopus 로고
    • Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface
    • Smith, G.P. Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. Science 228,1315-1317 (1985).
    • (1985) Science , vol.228 , pp. 1315-1317
    • Smith, G.P.1
  • 12
    • 0025838021 scopus 로고
    • Assembly of combinatorial antibody libraries on phage surfaces: The gene III site
    • Barbas, C.F. III, Kang, A.S., Lerner, R.A. & Benkovic, S.J. Assembly of combinatorial antibody libraries on phage surfaces: the gene III site. Proc. Natl. Acad. Sci. USA 88, 7978-7982 (1991).
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7978-7982
    • Barbas, C.1    Kang, A.S.2    Lerner, R.A.3    Benkovic, S.J.4
  • 13
    • 0036883549 scopus 로고    scopus 로고
    • The production of a genus- specific recombinant antibody (ScFv) using a recombinant potyvirus protease
    • Hust, M., Maiss, E., Jacobsen, H.J. & Reinard, T. The production of a genus- specific recombinant antibody (scFv) using a recombinant potyvirus protease. J. Virol. Methods 106, 225-233 (2002).
    • (2002) J. Virol. Methods , vol.106 , pp. 225-233
    • Hust, M.1    Maiss, E.2    Jacobsen, H.J.3    Reinard, T.4
  • 14
    • 0035368621 scopus 로고    scopus 로고
    • Site-specific anti-C3a receptor single-chain antibodies selected by differential panning on cellulose sheets
    • Hawlisch, H. et al. Site-specific anti-C3a receptor single-chain antibodies selected by differential panning on cellulose sheets. Anal. Biochem. 293, 142-145 (2001).
    • (2001) Anal. Biochem , vol.293 , pp. 142-145
    • Hawlisch, H.1
  • 15
    • 0141656689 scopus 로고    scopus 로고
    • Identification of scFv antibody fragments that specifically recognise the heroin metabolite 6-monoacetylmorphine but not morphine
    • Moghaddam, A. et al. Identification of scFv antibody fragments that specifically recognise the heroin metabolite 6-monoacetylmorphine but not morphine. J. Immunol. Methods 280, 139-155 (2003).
    • (2003) J. Immunol. Methods , vol.280 , pp. 139-155
    • Moghaddam, A.1
  • 16
    • 33846010537 scopus 로고    scopus 로고
    • Identification of human scFvs targeting atherosclerotic lesions: Selection by single round in vivo phage display
    • Robert, R. et al. Identification of human scFvs targeting atherosclerotic lesions: selection by single round in vivo phage display. J. Biol. Chem. 281, 40135-40143 (2006).
    • (2006) J. Biol. Chem , vol.281 , pp. 40135-40143
    • Robert, R.1
  • 17
    • 0033499630 scopus 로고    scopus 로고
    • Generation of a large complex antibody library from multiple donors
    • Little, M. et al. Generation of a large complex antibody library from multiple donors. J. Immunol. Methods 231, 3-9 (1999).
    • (1999) J. Immunol. Methods , vol.231 , pp. 3-9
    • Little, M.1
  • 18
    • 0342871971 scopus 로고    scopus 로고
    • Antibodies to steroids from a small human naive IgM library
    • Dorsam, H. et al. Antibodies to steroids from a small human naive IgM library. FEBS Lett. 414, 7-13 (1997).
    • (1997) FEBS Lett , vol.414 , pp. 7-13
    • Dorsam, H.1
  • 19
    • 0036697001 scopus 로고    scopus 로고
    • Integrin activation and structural rearrangement
    • Takagi, J. & Springer, T.A. Integrin activation and structural rearrangement. Immunol. Rev. 186, 141-163 (2002).
    • (2002) Immunol. Rev , vol.186 , pp. 141-163
    • Takagi, J.1    Springer, T.A.2
  • 20
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes, R.O. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69, 11-25 (1992).
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 21
    • 34147152321 scopus 로고    scopus 로고
    • Generation of activation-specific human anti-alphaMbeta2 single-chain antibodies as potential diagnostic tools and therapeutic agents
    • Eisenhardt, S.U. etal. Generation of activation-specific human anti-alphaMbeta2 single-chain antibodies as potential diagnostic tools and therapeutic agents. Blood 109, 3521-3528 (2007).
    • (2007) Blood , vol.109 , pp. 3521-3528
    • Eisenhardt, S.U.1
  • 22
    • 0029803982 scopus 로고    scopus 로고
    • Directing phage selections towards specific epitopes
    • Parsons, H.L. etal. Directing phage selections towards specific epitopes. Protein Eng. 9, 1043-1049 (1996).
    • (1996) Protein Eng , vol.9 , pp. 1043-1049
    • Parsons, H.L.1
  • 24
    • 0031902108 scopus 로고    scopus 로고
    • Directed selection of MIP-1 alpha neutralizing CCR5 antibodies from a phage display human antibody library
    • Osbourn, J.K. et al. Directed selection of MIP-1 alpha neutralizing CCR5 antibodies from a phage display human antibody library. Nat. Biotechnol. 16, 778-781 (1998).
    • (1998) Nat. Biotechnol , vol.16 , pp. 778-781
    • Osbourn, J.K.1
  • 25
    • 0032502930 scopus 로고    scopus 로고
    • Stochastic modeling and optimization of phage display
    • Levitan, B. Stochastic modeling and optimization of phage display. J. Mol. Biol. 277, 893-916 (1998).
    • (1998) J. Mol. Biol , vol.277 , pp. 893-916
    • Levitan, B.1
  • 26
    • 0034425742 scopus 로고    scopus 로고
    • Antibody arrays for high-throughput screening of antibody-antigen interactions
    • de Wildt, R.M., Mundy, C.R., Gorick, B.D. & Tomlinson, I.M. Antibody arrays for high-throughput screening of antibody-antigen interactions. Nat. Biotechnol. 18, 989-994 (2000).
    • (2000) Nat. Biotechnol , vol.18 , pp. 989-994
    • De Wildt, R.M.1    Mundy, C.R.2    Gorick, B.D.3    Tomlinson, I.M.4
  • 27
    • 0032801102 scopus 로고    scopus 로고
    • Di-, tri- and tetrameric single chain Fv antibody fragments against human CD19: Effect of valency on cell binding
    • Le Gall, F., Kipriyanov, S.M., Moldenhauer, G. & Little, M. Di-, tri- and tetrameric single chain Fv antibody fragments against human CD19: effect of valency on cell binding. FEBS Lett. 453,164-168 (1999).
    • (1999) FEBS Lett , vol.453 , pp. 164-168
    • Le Gall, F.1    Kipriyanov, S.M.2    Moldenhauer, G.3    Little, M.4
  • 28
    • 0031022084 scopus 로고    scopus 로고
    • High level production of soluble single chain antibodies in small-scale Escherichia coli cultures
    • Kipriyanov, S.M., Moldenhauer, G. & Little, M. High level production of soluble single chain antibodies in small-scale Escherichia coli cultures. J. Immunol. Methods 200, 69-77 (1997).
    • (1997) J. Immunol. Methods , vol.200 , pp. 69-77
    • Kipriyanov, S.M.1    Moldenhauer, G.2    Little, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.