-
2
-
-
14044274098
-
-
T. Pellegrino et al., Small 1, 48 (2005).
-
T. Pellegrino et al., Small 1, 48 (2005).
-
-
-
-
3
-
-
34948894584
-
-
M. Ringler et al., Nano Lett. 7, 2753 (2007).
-
(2007)
Nano Lett
, vol.7
, pp. 2753
-
-
Ringler, M.1
-
7
-
-
34848919386
-
-
G. Binnig, H. Rohrer, C. Gerber, E. Weibel, Phys. Rev. Lett. 49, 57 (1982).
-
(1982)
Phys. Rev. Lett
, vol.49
, pp. 57
-
-
Binnig, G.1
Rohrer, H.2
Gerber, C.3
Weibel, E.4
-
9
-
-
0024286273
-
-
P. K. Hansma, V. B. Elings, O. Marti, C. E. Bracker, Science 242, 209 (1988).
-
(1988)
Science
, vol.242
, pp. 209
-
-
Hansma, P.K.1
Elings, V.B.2
Marti, O.3
Bracker, C.E.4
-
10
-
-
0026917533
-
-
M. Radmacher, R. W. Tillmann, M. Fritz, H. E. Gaub, Science 257, 1900 (1992).
-
(1992)
Science
, vol.257
, pp. 1900
-
-
Radmacher, M.1
Tillmann, R.W.2
Fritz, M.3
Gaub, H.E.4
-
14
-
-
0033614026
-
-
R. D. Piner, J. Zhu, F. Xu, S. Hong, C. A. Mirkin, Science 283, 661 (1999).
-
(1999)
Science
, vol.283
, pp. 661
-
-
Piner, R.D.1
Zhu, J.2
Xu, F.3
Hong, S.4
Mirkin, C.A.5
-
15
-
-
38849125632
-
-
C. P. Collier et al., Science 289, 1172 (2000).
-
C. P. Collier et al., Science 289, 1172 (2000).
-
-
-
-
16
-
-
0026108692
-
-
S. P. Fodor et al., Science 251, 767 (1991).
-
(1991)
Science
, vol.251
, pp. 767
-
-
Fodor, S.P.1
-
17
-
-
0028566558
-
-
C. M. Niemeyer, T. Sano, C. L. Smith, C. R. Cantor, Nucleic Acids Res. 22, 5530 (1994).
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 5530
-
-
Niemeyer, C.M.1
Sano, T.2
Smith, C.L.3
Cantor, C.R.4
-
18
-
-
0030948781
-
-
E. Delamarche, A. Bernard, H. Schmid, B. Michel, H. Biebuyck, Science 276, 779 (1997).
-
(1997)
Science
, vol.276
, pp. 779
-
-
Delamarche, E.1
Bernard, A.2
Schmid, H.3
Michel, B.4
Biebuyck, H.5
-
20
-
-
0032403465
-
-
D. C. Duffy, J. C. McDonald, O. J. A. Schueller, G. M. Whitesides, Anal. Chem. 70, 4974 (1998).
-
(1998)
Anal. Chem
, vol.70
, pp. 4974
-
-
Duffy, D.C.1
McDonald, J.C.2
Schueller, O.J.A.3
Whitesides, G.M.4
-
21
-
-
0038638476
-
-
C. Albrecht et al., Science 301, 367 (2003).
-
(2003)
Science
, vol.301
, pp. 367
-
-
Albrecht, C.1
-
22
-
-
38849201872
-
-
A hand-waving argument: Upon separation, the binding energy is overcome in the shear geometry within a much shorter distance than in the unzip geometry, therefore the force to overcome the energy barrier is much lower in the unzip geometry. Because the forced unbinding of the oligomer in shear geometry is a nonequilibrium process, its unbinding force is rate-dependent. In all experiments shown here, the duplexes were loaded with a rate of 3000 pN/s.
-
A hand-waving argument: Upon separation, the binding energy is overcome in the shear geometry within a much shorter distance than in the unzip geometry, therefore the force to overcome the energy barrier is much lower in the unzip geometry. Because the forced unbinding of the oligomer in shear geometry is a nonequilibrium process, its unbinding force is rate-dependent. In all experiments shown here, the duplexes were loaded with a rate of 3000 pN/s.
-
-
-
-
23
-
-
0018101150
-
-
G. I. Bell, Science 200, 618 (1978).
-
(1978)
Science
, vol.200
, pp. 618
-
-
Bell, G.I.1
-
28
-
-
34848825294
-
-
J. Morfill et al., Biophys. J. 93, 2400 (2007).
-
(2007)
Biophys. J
, vol.93
, pp. 2400
-
-
Morfill, J.1
-
29
-
-
0033613073
-
-
T. Strunz, K. Oroszlan, R. Schafer, H. J. Guntherodt, Proc. Natl. Acad. Sci. U.S.A. 96, 11277 (1999).
-
(1999)
Proc. Natl. Acad. Sci. U.S.A
, vol.96
, pp. 11277
-
-
Strunz, T.1
Oroszlan, K.2
Schafer, R.3
Guntherodt, H.J.4
-
30
-
-
0029879228
-
-
R. D. Vale et al., Nature 380, 451 (1996).
-
(1996)
Nature
, vol.380
, pp. 451
-
-
Vale, R.D.1
-
35
-
-
38849159254
-
-
Helpful discussions with P. Hansma, G. M. Whitesides, J. Fernandez, H. Heus, P. Tinnefeld, J. Morfill, C. Albrecht, and L. Whetton are gratefully acknowledged. Supported by the German Science Foundation and the Nanosystems Initiative Munich
-
Helpful discussions with P. Hansma, G. M. Whitesides, J. Fernandez, H. Heus, P. Tinnefeld, J. Morfill, C. Albrecht, and L. Whetton are gratefully acknowledged. Supported by the German Science Foundation and the Nanosystems Initiative Munich.
-
-
-
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