DNA: A programmable force sensor

Science

Volumn 301, Issue 5631, 2003, Pages 367-370

  Albrecht, Christian ^a   Blank, Kerstin ^a   Lalic Mülthaler, Mio ^a   Hirler, Siegfried ^a   Mai, Thao ^a   Gilbert, Ilka ^a   Schiffmann, Susanne ^a   Bayer, Tom ^a   Clausen Schaumann, Hauke ^a   Gaub, Hermann E ^b  

^a Nanotype GmbH   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BIOSENSORS; CHEMICAL BONDS;

BIOMOLECULAR INTERACTION;

DNA;

DNA; DOUBLE STRANDED DNA;

DNA; PROTEIN; SENSOR;

ARTICLE; BASE MISPAIRING; CROSS REACTION; DNA BINDING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN BIOCHIP; REFERENCE VALUE; SEMICONDUCTOR; SENSITIVITY AND SPECIFICITY; SENSOR; SINGLE MOLECULE FORCE SPECTROSCOPY; SPECTROSCOPY;

ANIMALS; ANTIBODIES; BASE PAIR MISMATCH; BIOSENSING TECHNIQUES; CARBOCYANINES; CROSS REACTIONS; DIMETHYLPOLYSILOXANES; DNA; FLUORESCENCE; FLUORESCENT DYES; GLASS; HUMANS; IMMUNOASSAY; INTERLEUKIN-5; MICE; MICROSCOPY, ATOMIC FORCE; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HYBRIDIZATION; OLIGODEOXYRIBONUCLEOTIDES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN ARRAY ANALYSIS; PROTEIN BINDING; SILICONES; TEMPERATURE; THERMODYNAMICS;

EID: 0038638476     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1084713     Document Type: Article

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51. We thank M. Rief for kindly providing the total internal reflection flourescence (TIRF) data showing single-molecule fluorescence, M. Benoit for technical support, F. Oesterhelt, C. Duschl, and D. Mendik for helpful discussions. Supported by the Nanobiotechnology and Proteomics program of the Bundesministerium for Bildung and Forschung (grants 13N8141 and O312821A) and the Bayerische Forschungsstiftung.