Differential epigenetic regulation of Aiolos expression in human tumoral cell lines and primary cells

FEBS Letters

Volumn 582, Issue 3, 2008, Pages 457-467

  Duhamel, Marianne ^a   Navarro, Pablo ^b   Cario Andre, Muriel ^c   Billot, Katy ^a   Arrouss, Issam ^a   Rebollo, Angelita ^a  

^a Laboratoire d'Immunologie Cellulaire et Tissulaire CNRS URA 625   (France)

^b INSTITUT PASTEUR   (France)

^c UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

Aiolos; CpG islands; DNA methylation; Histone modifications; Transcriptional regulation

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; HISTONE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AIOLOS; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EPIGENETICS; EUCHROMATIN; GENE SILENCING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL;

ACETYLATION; ANTINEOPLASTIC AGENTS; AZACITIDINE; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CHROMATIN; CPG ISLANDS; DNA METHYLATION; DRUG COMBINATIONS; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONE ACETYLTRANSFERASES; HISTONES; HUMANS; HYDROXAMIC ACIDS; JURKAT CELLS; NEOPLASMS; PROMOTER REGIONS (GENETICS); TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; U937 CELLS;

EID: 38749125842     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.01.010     Document Type: Article

References (25)

1. Glimcher L.H., and Singh H. Transcription factors in lymphocyte development-T and B cells get together. Cell 96 (1999) 13-23
2. Georgopoulos K., Moore D.D., and Derfler B. Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment. Science 258 (1992) 808-812
3. Morgan B., et al. Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation. Embo J. 16 (1997) 2004-2013
4. Winandy S., Wu P., and Georgopoulos K. A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma. Cell 83 (1995) 289-299
5. Nakase K., Ishimaru F., Fujii K., Tabayashi T., Kozuka T., Sezaki N., Matsuo Y., and Harada M. Overexpression of novel short isoforms of Helios in a patient with T-cell acute lymphoblastic leukemia. Exp. Hematol. 30 (2002) 313-317
6. Romero F., Martinez A.C., Camonis J., and Rebollo A. Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization. Embo J. 18 (1999) 3419-3430
7. Vignali M., Hassan A.H., Neely K.E., and Workman J.L. ATP-dependent chromatin-remodeling complexes. Mol. Cell Biol. 20 (2000) 1899-1910
8. Lee D.Y., Hayes J.J., Pruss D., and Wolffe A.P. A positive role for histone acetylation in transcription factor access to nucleosomal DNA. Cell 72 (1993) 73-84
9. Roh T.Y., Cuddapah S., Cui K., and Zhao K. The genomic landscape of histone modifications in human T cells. Proc. Natl. Acad. Sci. USA 103 (2006) 15782-15787
10. Zhu X., Asa S.L., and Ezzat S. Ikaros is regulated through multiple histone modifications and DNA methylation in the pituitary. Mol. Endocrinol. 21 (2007) 1205-1215
11. Navarro P., Page D.R., Avner P., and Rougeulle C. Tsix-mediated epigenetic switch of a CTCF-flanked region of the Xist promoter determines the Xist transcription program. Genes Dev. 20 (2006) 2787-9272
12. Ghadiri A., Duhamel M., Fleischer A., Reimann A., Dessauge F., and Rebollo A. Critical function of Ikaros in controlling Aiolos gene expression. FEBS Lett. 581 (2007) 1605-1616
13. Park J.G., and Chapman V.M. CpG island promoter region methylation patterns of the inactive-X-chromosome hypoxanthine phosphoribosyltransferase (Hprt) gene. Mol. Cell Biol. 14 (1994) 7975-7983
14. Campanero M.R., Armstrong M.I., and Flemington E.K. CpG methylation as a mechanism for the regulation of E2F activity. Proc. Natl. Acad. Sci. USA 97 (2000) 6481-6486
15. Kass S.U., Landsberger N., and Wolffe A.P. DNA methylation directs a time-dependent repression of transcription initiation. Curr. Biol. 7 (1997) 157-165
16. McKeon C., Ohkubo H., Pastan I., and de Crombrugghe B. Unusual methylation pattern of the alpha 2 (l) collagen gene. Cell 29 (1982) 203-210
17. Bird A.P., Taggart M.H., Nicholls R.D., and Higgs D.R. Non-methylated CpG-rich islands at the human alpha-globin locus: implications for evolution of the alpha-globin pseudogene. Embo J. 6 (1987) 999-1004
18. Sims III R.J., Chen C.F., Santos-Rosa H., Kouzarides T., Patel S.S., and Reinberg D. Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains. J. Biol. Chem. 280 (2005) 41789-41792
19. Wysocka J., et al. WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell 121 (2005) 859-872
20. Francis N.J., Kingston R.E., and Woodcock C.L. Chromatin compaction by a polycomb group protein complex. Science 306 (2004) 1574-1577
21. Kirmizis A., Bartley S.M., Kuzmichev A., Margueron R., Reinberg D., Green R., and Farnham P.J. Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27. Genes Dev. 18 (2004) 1592-1605
22. Koyanagi M., Baguet A., Martens J., Margueron R., Jenuwein T., and Bix M. EZH2 and histone 3 trimethyl lysine 27 associated with Il4 and Il13 gene silencing in Th1 cells. J. Biol. Chem. 280 (2005) 31470-31477
23. Bernstein B.E., et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125 (2006) 315-326
24. Cameron E.E., Bachman K.E., Myohanen S., Herman J.G., and Baylin S.B. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat. Genet. 21 (1999) 103-107
25. Selker E.U. Trichostatin A causes selective loss of DNA methylation in neurospora. Proc. Natl. Acad. Sci. USA 95 (1998) 9430-9435