The role of loop and β-turn residues as structural and functional determinants for the lipoyl domain from the Escherichia coli 2-oxoglutarate dehydrogenase complex

Biochemical Journal

Volumn 409, Issue 2, 2008, Pages 357-366

  Jones, D Dafydd ^a,b   Perham, Richard N ^c  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c NONE

Author keywords

2 oxoglutarate dehydrogenase; Lipoyl domain; Post translational modification; Protein misfolding; Protein protein interaction; Substrate channelling

Indexed keywords

ACETYLATION; AMINO ACIDS; ESCHERICHIA COLI; PROTEINS;

LIPOIC ACID; LIPOYL DOMAIN STRUCTURE; MULTIENZYME COMPLEX; PROTEIN MISFOLDING; PROTEIN-PROTEIN INTERACTION; SUBSTRATE CHANNELLING;

ENZYME ACTIVITY;

BACTERIAL ENZYME; DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE; LYSINE; OXOGLUTARATE DEHYDROGENASE; PYRUVATE DECARBOXYLASE; PYRUVATE DEHYDROGENASE; THIOCTIC ACID; THREONINE;

ACETYLATION; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; ESCHERICHIA COLI; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

ACYLTRANSFERASES; CARBOXY-LYASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; KETOGLUTARATE DEHYDROGENASE COMPLEX; LIPOYLATION; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OXIDATION-REDUCTION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

ESCHERICHIA COLI;

EID: 38749121746     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20071119     Document Type: Article

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