Molecular architecture and mechanism of an icosahedral pyruvate dehydrogenase complex: A multifunctional catalytic machine

EMBO Journal

Volumn 21, Issue 21, 2002, Pages 5587-5598

  Milne, Jacqueline L S ^a   Shi, Dan ^a   Rosenthal, Peter B ^a   Sunshine, Joshua S ^a   Domingo, Gonzalo J ^a   Wu, Xiongwu ^a   Brooks, Bernard R ^a   Perham, Richard N ^a   Henderson, Richard ^a   Subramaniam, Sriram ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Electron microscopy; Molecular machine; Pyruvate dehydrogenase; Single particle analysis; Three dimensional reconstruction

Indexed keywords

ACETYL COENZYME A; LIPID; PYRUVATE DEHYDROGENASE; PYRUVIC ACID;

ARTICLE; CATALYSIS; CITRIC ACID CYCLE; COMPLEX FORMATION; CRYOELECTRON MICROSCOPY; DECARBOXYLATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STRUCTURE; GLYCOLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; THREE DIMENSIONAL IMAGING;

CATALYSIS; MICROSCOPY, ELECTRON; PROTEIN CONFORMATION; PYRUVATE DEHYDROGENASE COMPLEX;

EID: 18744386656     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf574     Document Type: Article

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