Recognition of a surface loop of the lipoyl domain underlies substrate channelling in the pyruvate dehydrogenase multienzyme complex

Journal of Molecular Biology

Volumn 263, Issue 3, 1996, Pages 463-474

  Wallis, Nicola G ^a,d   Allen, Mark D ^a,b   Broadhurst, R William ^a   Lessard, Ivan A D ^a,c   Perham, Richard N ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b NATL INST BIOSCI HUM TECHNOL   (Japan)

^c HARVARD MEDICAL SCHOOL   (United States)

^d GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Lipoyl domain; Molecular recognition; Protein structure; Pyruvate dehydrogenase complex; Substrate channeling

Indexed keywords

ACYLTRANSFERASE; LYSINE; MULTIENZYME COMPLEX; NITROGEN 15; PYRUVATE DEHYDROGENASE;

AMINO TERMINAL SEQUENCE; ARTICLE; ENZYME SUBSTRATE; GENE MUTATION; GEOBACILLUS STEAROTHERMOPHILUS; MOLECULAR RECOGNITION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

GEOBACILLUS STEAROTHERMOPHILUS;

EID: 0030298405     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0589     Document Type: Article

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