Differential involvement of mitochondria during ursolic acid-induced apoptotic process in HaCaT and M4Beu cells

Oncology Reports

Volumn 19, Issue 1, 2008, Pages 145-149

  Duval, Raphaël Emmanuel ^a,d   Harmand, Pierre Olivier ^a,e   Jayat Vignoles, Chantal ^b   Cook Moreau, Jeanne ^c   Pinon, Aline ^a   Delage, Christiane ^a   Simon, Alain ^a  

^a UNIVERSITY OF LIMOGES   (France)

^b CNRS   (France)

^c FR 3503 GEIST EA 1069 Laboratoire de Chimie des Substances Naturelles GDR CNRS 3049 Faculte de Ph   (France)

^d NANCY UNIVERSITÉ   (France)

^e INSERM   (France)

Author keywords

Apoptosis; HaCaT; M4Beu; Mitochondria; Ursolic acid

Indexed keywords

PROTEIN BAX; PROTEIN BCL 2; TRITERPENOID; URSOLIC ACID;

APOPTOSIS; ARTICLE; CANCER CELL; CELL PROLIFERATION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; KERATINOCYTE; MELANOMA CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PLEIOTROPY; PRIORITY JOURNAL; STAINING; WESTERN BLOTTING;

EID: 38749121666     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: 10.3892/or.19.1.145     Document Type: Article

References (32)

1. Liu J: Oleanolic acid and ursolic acid: research perspectives. J Ethnopharmacol 100: 92-94, 2005.
2. Rona C, Vailati F and Berardesca E: The cosmetic treatment of wrinkles. J Cosmet Dermatol 3: 26-34, 2004.
3. Yarosh DB, Both D and Brown D: Liposomal ursolic acid (merotaine) increases ceramides and collagen in human skin. Horm Res 54: 318-321, 2000.
4. Soo Lee Y, Jinn DQ, Beak SM, Lee ES and Kim JA: Inhibition of ultraviolet-A-modulated signaling pathways by asiatic acid and ursolic acid in HaCaT human keratinocytes. Eur J Pharmacol 476: 173-178, 2003.
5. Huang MT, Ho CT, Wang ZY, et al: Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid. Cancer Res 54: 701-708, 1994.
6. Tokuda H, Ohigashi H, Koshimizu K and Ito Y: Inhibitory effects of ursolic and oleanolic acid on skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Cancer Lett 33: 279-285, 1986.
7. Baek JH, Lee YS, Kang CM, Kim JA, Kwon KS, Son HC and Kim KW: Intracellular Ca2+ release mediates ursolic acid-induced apoptosis in human leukemic HL-60 cells. Int J Cancer 73: 725-728, 1997.
8. Lauthier F, Taillet L, Trouillas P, Delage C and Simon A: Ursolic acid triggers calcium-dependent apoptosis in human Daudi cells. Anticancer Drugs 11: 737-745, 2000.
9. Hollosy F, Idei M, Csorba G, et al: Activation of caspase-3 protease during the process of ursolic acid and its derivative-induced apoptosis. Anticancer Res 21: 3485-3491, 2001.
10. Hsu YL, Kuo PL and Lin CC: Proliferative inhibition, cell-cycle dysregulation, and induction of apoptosis by ursolic acid in human non-small cell lung cancer A549 cells. Life Sci 75: 2303-2316, 2004.
11. Satomi Y, Nishino H and Shibata S: Glycyrrhetinic acid and related compounds induce G1 arrest and apoptosis in human hepatocellular carcinoma HepG2. Anticancer Res 25: 4043-4047, 2005.
12. Achiwa Y, Hasegawa K, Komiya T and Udagawa Y: Ursolic acid induces Bax-dependent apoptosis through the caspase-3 pathway in endometrial cancer SNG-II cells. Oncol Rep 13: 51-57, 2005.
13. Achiwa Y, Hasegawa K and Udagawa Y: Molecular mechanism of ursolic acid induced apoptosis in poorly differentiated endometrial cancer HEC108 cells. Oncol Rep 14: 507-512, 2005.
14. Hannand PO, Duval R, Liagre B, Jayat-Vignoles C, Beneytout JL, Delage C and Simon A: Ursolic acid induces apoptosis through caspase-3 activation and cell cycle arrest in HaCat cells. Int J Oncol 23: 105-112, 2003.
15. Harmand PO, Duval R, Delage C and Simon A: Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and caspase-3 activation in M4Beu melanoma cells, Int J Cancer 114: 1-11, 2005.
16. Roy S and Nicholson DW: Cross-talk in cell death signalling. J Exp Med 192: 21-26, 2000.
17. Stennicke HR, Jurgensmeier JM, Shin H, et al: Pro-caspase-3 is a major physiologic target of caspase-8. J Biol Chem 273: 27084-27090, 1998.
18. Antonsson B and Martinou JC: The Bcl-2 protein family. Exp Cell Res 256: 50-57, 2000.
19. Borner C: The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions. Mol Immunol 39: 615-647, 2003.
20. Zuliani T, Duval R, Jayat C, Schnebert S, Andre P, Dumas M and Ratinaud MH: Sensitive and reliable JC-1 and TOTO-3 double staining to assess mitochondrial transmembrane potential and plasma membrane integrity: interest for cell death investigations. Cytometry 54: 100-108, 2003.
21. Liu J: Pharmacology of oleanolic acid and ursolic acid. J Ethnopharmacol 49: 57-68, 1995.
22. Novotny L, Vachalkova A and Biggs D: Ursolic acid: an antitumorigenic and chemopreventive activity (Minireview). Neoplasma 48: 241-246, 2001.
23. Ovesna Z, Vachalkova A, Horvathova K and Tothova D: Pentacyclic triterpenoic acids: new chemoprotective compounds (Minireview). Neoplasma 51: 327-333, 2004.
24. Alnemri ES, Livingston DJ, Nicholson DW, Salvesen G, Thornberry NA, Wong WW and Yuan J: Human ICE/CED-3 protease nomenclature. Cell 87: 171, 1996.
25. Earnshaw WC, Martins LM and Kaufmann SH: Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu Rev Biochem 68: 383-424, 1999.
26. Loeffler M and Kroemer G: The mitochondrion in cell death control: certainties and incognita. Exp Cell Res 256: 19-26, 2000.
27. Reed JC, Jurgensmeier JM and Matsuyama S: Bcl-2 family proteins and mitochondria. Biochim Biophys Acta 1366: 127-137, 1998.
28. Darzynkiewicz Z, Traganos F, Staiano-Coico L, Kapuscinski J and Melamed MR: Interaction of rhodamine 123 with living cells studied by flow cytometry. Cancer Res 42: 799-806, 1982.
29. Shapiro HM: Cell membrane potential analysis. Methods Cell Biol 41: 121-133, 1994.
30. Cossarizza A, Baccarani-Contri M, Kalashnikova G and Franceschi C: A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro- 1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1). Biochem Biophys Res Connnun 197: 40-45, 1993.
31. Kroemer G and Reed JC: Mitochondrial control of cell death. Nat Med 6: 513-519, 2000.
32. Kroemer G: Mitochondrial control of apoptosis. Bull Acad Natl Med 185: 1135-1143, 2001.