Synthesis and bioactivity evaluation of ethyl 1-arylmethyl-3-aryl-1H- pyrazole-5-carboxylate derivatives

Chinese Journal of Organic Chemistry

Volumn 27, Issue 12, 2007, Pages 1542-1546

  Ding, Xiao Ling ^a,b   Meng, Ning ^a   Xia, Yong ^a   Wang, Li Juan ^a,c   Zhang, Xiao Feng ^a   Zhao, Bao Xiang ^a   Miao, Jun Ying ^a  

^a SHANDONG UNIVERSITY   (China)

^b QINGDAO UNIVERSITY   (China)

^c Qingdao DIC Fine Chemical Co Ltd   (China)

Author keywords

Apoptosis; Characterization; Pyrazole derivative; Synthesis; Vascular endothelial cell

Indexed keywords

EID: 38749119390     PISSN: 02532786     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Tao, Z. F.; Sowin, T. J.; Lin, N.-H. Tetrahedron Lett. 2005, 46, 7615.
2. Yoshida, M.; Hayakawa, I.; Hayashi, N.; Agatsuma, T.; Oda, Y.; Tanzawa, F.; Iwasaki, S.; Koyama, K.; Furukawa, H.; Kurakata, S.; Sugano, Y. Bioorg. Med. Chem. Lett. 2005, 15, 3328.
3. Li, J.; Lynch, M. P.; DeMello, K. L.; Sakya, S. M.; Cheng, H.; Rafka, R. J.; Bronk, B. S.; Jaynes, B. H.; Kilroy, C.; Mann, D. W.; Haven, M. L.; Kolosko, N. L.; Petras, C.; Seibel, S. C.; Lund, L. A. Bioorg. Med. Chem. 2005, 13, 1805.
4. Sato, N.; Takahashi, T.; Shibata, T.; Haga, Y.; Sakuraba, A.; Hirose, M.; Sato, M.; Nonoshita, K.; Koike, Y.; Kitazawa, H.; Fujino, N.; Ishii, Y.; Ishihara, A.; Kanatani, A.; Fukami, T. J. Med. Chem. 2003, 46, 666.
5. Wen, L.-Y.; Li, M.; Jing, S.-X.; Cao, W.; Yang, H.-Z. Chin. J. Org. Chem. 2005, 25, 197 (in Chinese).
6. Tan, C.-X.; Shen, D.-L.; Weng, J.-Q.; Ou, X.-M. Chin. J. Org. Chem. 2005, 25, 1454 (in Chinese).
7. Wang, H.-Q.; Liu, H.; Liu, Z.-J. Chin. J. Org. Chem. 2004, 24, 1563 (in Chinese).
8. Jin, M.; Yang, Q.-X.; Lu, R.; Pan, L.-Y.; Zhao, Y.-Y. Chem. J. Chin. Univ. 2003, 24, 143 (in Chinese).
9. Brough, P. A.; Barril, X.; Beswick, M.; Dymock, B. W.; Drysdale, M. J.; Wright, L.; Grant, K.; Massey, A.; Surgenor, A.; Workman, P. Bioorg. Med. Chem. Lett. 2005, 15, 5197.
10. Du, H.-T.; Ouyang, G.-P.; Du, H.-J.; Shi, D.-B.; Jin, L.-H. Chin. J. Org. Chem. 2006, 26, 383 (in Chinese).
11. Alekseeva, O. O.; Mahadevan, A.; Wiley, J. L.; Martin, B. R.; Razdan, R. K. Tetrahedron Lett. 2005, 46, 2159.
12. Demir, A. S.; Emrullahoglu, M. Tetrahedron 2005, 61, 10482.
13. Zhao, B.-X.; Wang, D.-W.; Zuo, H.; Qiang, G.-T.; Miao, J.-Y. Chin. J. Org. Chem. 2003, 23, 1026 (in Chinese).
14. Tan, W.; Zhao, B.-X.; Shi, M.; Sha, L.; Miao, J.-Y.; Shin, D.-S. Chin. J. Chem. 2006, 24, 396.
15. Tan, W.; Zhao, B.-X.; Sha, L.; Jiao, P.-F.; Wan, M.-S.; Lei, S. Chin. J. Org. Chem. 2005, 25, 1011 (in Chinese).
16. Tan, W.; Zhao, B.-X.; Sha, L.; Jiao, P.-F.; Wan, M.-S.; Su, L.; Shin, D.-S. Synth. Commun. 2006, 36, 1353.
17. Wan, M.-S.; Zhao, B.-X.; He, Q.-X.; Jiao, P.-F.; Wang, D.-W.; Miao, J.-Y. Chin. J. Org. Chem. 2006, 26, 1248 (in Chinese).
18. Jiao, P.-F.; Zhao, B.-X.; Wang, W.-W.; He, Q.-X.; Wan, M.-S.; Shin, D.-S.; Miao, J.-Y. Bioorg. Med. Chem. Lett. 2006, 16, 2862.
19. Wei, F.; Zhao, B.-X.; Huang, B.; Zhang, L.; Sun, C.-H.; Dong, W.-L.; Shin, D.-S.; Miao, J.-Y. Bioorg. Med. Chem. Lett. 2006, 16, 6342.
20. Crane, J. D.; Fox, O. D.; Sinn, E. J. Chem. Soc., Dalton Trans. 1999, 1461.
21. Cusmano Gaeetta Chim. Ital. 1940, 70, 235.
22. Xia, Y.; Ding, X.-L.; Ge, Y.-Q.; Liu, L.-D.; Zhao, B.-X. Acta Crystallogr. 2007, E63, o394.