Synthesis of novel 5-substituted pyrazole derivatives as cannabinoid antagonists

Tetrahedron Letters

Volumn 46, Issue 12, 2005, Pages 2159-2161

  Alekseeva, Olga O ^a   Mahadevan, Anu ^a   Wiley, Jenny L ^b   Martin, Billy R ^b   Razdan, Raj K ^a  

^a ORGANIX INC   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antagonists; Cannabinoid receptors; Substituted pyrazoles; Synthesis

Indexed keywords

CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; PYRAZOLE DERIVATIVE; RIMONABANT;

ARTICLE; BINDING AFFINITY; DRUG BINDING; DRUG INDICATION; DRUG POTENCY; DRUG SYNTHESIS; OBESITY; PROCESS DEVELOPMENT; QUANTUM YIELD; SUBSTITUTION REACTION; SUZUKI REACTION;

EID: 14644406845     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.01.165     Document Type: Article

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