Biotransformation of lithocholic acid by rat hepatic microsomes: Metabolite analysis by liquid chromatography/mass spectrometry

Drug Metabolism and Disposition

Volumn 36, Issue 2, 2008, Pages 442-450

  Deo, Anand K ^a   Bandiera, Stelvio M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

3 OXOCHOLANIC ACID; 6 KETOLITHOCHOLIC ACID; ALPHA MURICHOLIC ACID; BETA MURICHOLIC ACID; BILE ACID; CHENODEOXYCHOLIC ACID; CHOLIC ACID; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2A; CYTOCHROME P450 2A2; CYTOCHROME P450 2B1; CYTOCHROME P450 2C; CYTOCHROME P450 2C11; CYTOCHROME P450 2C13; CYTOCHROME P450 2C6; CYTOCHROME P450 2D1; CYTOCHROME P450 2D6; CYTOCHROME P450 3A1; CYTOCHROME P450 3A2; DEOXYCHOLIC ACID; HYODEOXYCHOLIC ACID; ISOLITHOCHOLIC ACID; LITHOCHOLIC ACID; MURIDEOXYCHOLIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CATALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; DETOXIFICATION; FEMALE; HYDROXYLATION; LIQUID CHROMATOGRAPHY; LIVER METABOLISM; LIVER MICROSOME; MALE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT;

ANIMALS; BIOTRANSFORMATION; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; LITHOCHOLIC ACID; MALE; MASS SPECTROMETRY; MICROSOMES, LIVER; RATS; RATS, LONG-EVANS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECOMBINANT PROTEINS;

RATTUS;

EID: 38749105796     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.017533     Document Type: Article

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