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Volumn 19, Issue 1, 2005, Pages 114-123

DNA sequence analysis of 1-nitropyrene-4,5-oxide and 1-nitropyrene-9,10- oxide induced mutations in the hprt gene of Chinese hamster ovary cells

Author keywords

1 Nitropyrene 4,5 Oxide; 1 Nitropyrene 9,10 Oxide; Hprt gene; Mutagen; Mutation Spectrum

Indexed keywords

1 NITROPYRENE; 1 NITROPYRENE 4,5 EPOXIDE; 1 NITROPYRENE 9,10 EPOXIDE; ADENINE; ALANINE; DIMETHYL SULFOXIDE; GLYCINE; GUANINE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MESSENGER RNA; PURINE DERIVATIVE; UNCLASSIFIED DRUG; 1-NITROPYRENE-4,5-OXIDE; 1-NITROPYRENE-9,10-OXIDE; MUTAGENIC AGENT; PYRENE DERIVATIVE;

EID: 22844436532     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (46)
  • 1
    • 0031857816 scopus 로고    scopus 로고
    • Ki-ras mutation and cell proliferation of lung lesions induced by 1-nitropyrene in A/J mice
    • Bai, F., Nakanishi, Y., Takayama, K., Pei, X. H., Tokiwa, H., et al. (1998) Ki-ras mutation and cell proliferation of lung lesions induced by 1-nitropyrene in A/J mice. Mol. Carcinogenesis 22, 258-264.
    • (1998) Mol. Carcinogenesis , vol.22 , pp. 258-264
    • Bai, F.1    Nakanishi, Y.2    Takayama, K.3    Pei, X.H.4    Tokiwa, H.5
  • 2
    • 0000037422 scopus 로고
    • Metabolic activation and DNA adducts of aromatic amines and nitroaromatic hydrocarbons
    • Cooper, C. S. and Grover, P. L. (eds.), Springer-Verlag, Berlin
    • Beland, F. A. and Kadlubar, F. F. (1990) Metabolic activation and DNA adducts of aromatic amines and nitroaromatic hydrocarbons; in Handbook of Experimental Pharmacology, Vol. 94, Cooper, C. S. and Grover, P. L. (eds.), pp. 267-325, Springer-Verlag, Berlin.
    • (1990) Handbook of Experimental Pharmacology , vol.94 , pp. 267-325
    • Beland, F.A.1    Kadlubar, F.F.2
  • 3
    • 0026731367 scopus 로고
    • Metabolic activation of 1-nitropyrene to a mammalian cell mutagen and a carcinogen
    • Beland, F. A., Smith, B. A., Thornton-Mannins, J. R., and Heflich, R. H. (1992) Metabolic activation of 1-nitropyrene to a mammalian cell mutagen and a carcinogen. Xenobiotica 22, 1121-1133.
    • (1992) Xenobiotica , vol.22 , pp. 1121-1133
    • Beland, F.A.1    Smith, B.A.2    Thornton-Mannins, J.R.3    Heflich, R.H.4
  • 4
    • 0033118956 scopus 로고    scopus 로고
    • Comparative metabolism of 1-, 2-, and 4-nitropyrene by human hepatic and pulmonary microsomes
    • Chae, Y.-H., Tomas, T., Guengerich, F. P., Fu, P. P., and El-Bayoumy, K. (1999) Comparative metabolism of 1-, 2-, and 4-nitropyrene by human hepatic and pulmonary microsomes. Cancer Res. 59, 1473-1480.
    • (1999) Cancer Res. , vol.59 , pp. 1473-1480
    • Chae, Y.-H.1    Tomas, T.2    Guengerich, F.P.3    Fu, P.P.4    El-Bayoumy, K.5
  • 6
    • 0024544818 scopus 로고
    • Mutagenicity of the phenolic microsomal metabolites of 3-nitrofluoranthene and 1 -nitropyrene in strains of Samonella typhimurium
    • Console, M. C., Anders, M., and Howard, P. C. (1989) Mutagenicity of the phenolic microsomal metabolites of 3-nitrofluoranthene and 1 -nitropyrene in strains of Samonella typhimurium. Muatat. Res. 210, 263-269.
    • (1989) Muatat. Res. , vol.210 , pp. 263-269
    • Console, M.C.1    Anders, M.2    Howard, P.C.3
  • 7
    • 0022991291 scopus 로고
    • Oxidative microsomal metabolism of 1-nitropyrene and DNA-binding of oxidized metabolites following nitroreduction
    • Djuric, Z., Fifer, E. K., Howard, P. C., and Beland, F. A. (1986) Oxidative microsomal metabolism of 1-nitropyrene and DNA-binding of oxidized metabolites following nitroreduction. Carcinogenesis 7, 1073-1079.
    • (1986) Carcinogenesis , vol.7 , pp. 1073-1079
    • Djuric, Z.1    Fifer, E.K.2    Howard, P.C.3    Beland, F.A.4
  • 8
    • 0023638696 scopus 로고
    • In vivo and in vitro formation of glutathione conjugates from the K-region epoxides of 1-nitropyrene
    • Djuric, Z., Coles, B., Fifer, E. K., Ketterer, B., and Beland, F. A. (1987) In vivo and in vitro formation of glutathione conjugates from the K-region epoxides of 1-nitropyrene. Carcinogenesis 8, 1781-1786.
    • (1987) Carcinogenesis , vol.8 , pp. 1781-1786
    • Djuric, Z.1    Coles, B.2    Fifer, E.K.3    Ketterer, B.4    Beland, F.A.5
  • 9
    • 0020957475 scopus 로고
    • The role of intestinal microflora in the metabolic reduction of 1-nitropyrene to 1-aminopyrene in conventional and germfree rats and in humans
    • El-Bayoumy, K., Sharma, C., Louis, Y. M., Reddy, B., and Hecht S. S. (1983) The role of intestinal microflora in the metabolic reduction of 1-nitropyrene to 1-aminopyrene in conventional and germfree rats and in humans. Cancer Lett. 19, 311-316.
    • (1983) Cancer Lett. , vol.19 , pp. 311-316
    • El-Bayoumy, K.1    Sharma, C.2    Louis, Y.M.3    Reddy, B.4    Hecht, S.S.5
  • 10
    • 0021715043 scopus 로고
    • Tumorigenicity and metabolism of 1-nitropyrene in A/J mice
    • El-Bayoumy, K., Hecht, S. S., Sackl, T., and Stoner, G. D. (1984a) Tumorigenicity and metabolism of 1-nitropyrene in A/J mice. Carcinogenesis 5, 1449-1452.
    • (1984) Carcinogenesis , vol.5 , pp. 1449-1452
    • El-Bayoumy, K.1    Hecht, S.S.2    Sackl, T.3    Stoner, G.D.4
  • 11
    • 0021188119 scopus 로고
    • Identification of ring oxidized metabolites of 1-nitropyrene in the feces and urine of germfree F344 rats
    • El-Bayoumy, K., Reddy, B., and Hecht, S. S. (1984b) Identification of ring oxidized metabolites of 1-nitropyrene in the feces and urine of germfree F344 rats. Carcinogenesis 5, 1371-1373.
    • (1984) Carcinogenesis , vol.5 , pp. 1371-1373
    • El-Bayoumy, K.1    Reddy, B.2    Hecht, S.S.3
  • 12
    • 0022893941 scopus 로고
    • Synthesis and mutagenicity of 1-nitropyrene 4,5-oxide and 1-nitropyrene 9,10-oxide, microsomal metabolites of 1-nitropyrene
    • Fifer, E. K., Howard, P. C., Heflich, R. H., and Beland, F. A. (1986) Synthesis and mutagenicity of 1-nitropyrene 4,5-oxide and 1-nitropyrene 9,10-oxide, microsomal metabolites of 1-nitropyrene. Mutagenesis 1, 433-438.
    • (1986) Mutagenesis , vol.1 , pp. 433-438
    • Fifer, E.K.1    Howard, P.C.2    Heflich, R.H.3    Beland, F.A.4
  • 13
    • 0030976320 scopus 로고    scopus 로고
    • Strand asymmetries in DNA evolution
    • Francino, M. P. and Ochman, H. (1997) Strand asymmetries in DNA evolution. Trends. Genet. 13, 240-245.
    • (1997) Trends. Genet. , vol.13 , pp. 240-245
    • Francino, M.P.1    Ochman, H.2
  • 14
    • 0021914480 scopus 로고
    • 1-Nitropyrene: An intermediate in the metabolic activation of 1-nitropyrene to a mutagen in Samonella typhimurium TA1538
    • Heflich, R. H., Howard, P. C., and Beland, F. A. (1985) 1-Nitropyrene: an intermediate in the metabolic activation of 1-nitropyrene to a mutagen in Samonella typhimurium TA1538. Mutat. Res. 149, 25-32.
    • (1985) Mutat. Res. , vol.149 , pp. 25-32
    • Heflich, R.H.1    Howard, P.C.2    Beland, F.A.3
  • 15
    • 0022544160 scopus 로고
    • An examination of the weak mutagenic response of 1-nitropyrene in Chinese hamster ovary cells
    • Heflich, R. H., Fullerton, N. F., and Beland, F. A. (1986) An examination of the weak mutagenic response of 1-nitropyrene in Chinese hamster ovary cells. Mutat. Res. 161, 99-108.
    • (1986) Mutat. Res. , vol.161 , pp. 99-108
    • Heflich, R.H.1    Fullerton, N.F.2    Beland, F.A.3
  • 16
    • 0025042152 scopus 로고
    • Mutagenicity of oxidized microsomal metabolites of 1-nitropyrene in Chinese hamster ovary cells
    • Heflich, R. H., Thornton-Manning, J. R., Kinouchi, T., and Beland, F. A. (1990) Mutagenicity of oxidized microsomal metabolites of 1-nitropyrene in Chinese hamster ovary cells. Mutagenesis 5, 151-157.
    • (1990) Mutagenesis , vol.5 , pp. 151-157
    • Heflich, R.H.1    Thornton-Manning, J.R.2    Kinouchi, T.3    Beland, F.A.4
  • 17
    • 0021325373 scopus 로고
    • Induction of rat mammary gland tumors by 1-nitropyrene, a recently recognized environmental mutagen
    • Hirose, M., Lee, M. S., Wang, C. Y., and King, C. M. (1984) Induction of rat mammary gland tumors by 1-nitropyrene, a recently recognized environmental mutagen. Cancer Res. 44, 1158-1162.
    • (1984) Cancer Res. , vol.44 , pp. 1158-1162
    • Hirose, M.1    Lee, M.S.2    Wang, C.Y.3    King, C.M.4
  • 18
    • 0020966452 scopus 로고
    • Reduction of the carcinogen 1-nitropyrene to 1-aminopyrene by rat intestinal bacteria
    • Howard, P. C., Beland, F. A., and Cerniglia, C. E. (1983a) Reduction of the carcinogen 1-nitropyrene to 1-aminopyrene by rat intestinal bacteria. Carcinogenesis 4, 985-990.
    • (1983) Carcinogenesis , vol.4 , pp. 985-990
    • Howard, P.C.1    Beland, F.A.2    Cerniglia, C.E.3
  • 19
    • 0020583530 scopus 로고
    • Transformation of normal human skin fibroblasts by 1-nitropyrene and 6-nitrobenzopyrene
    • Howard, P. C., Gerard, J. A., Milo, C. E., Fu, P. P., Beland, F. A., et al. (1983b) Transformation of normal human skin fibroblasts by 1-nitropyrene and 6-nitrobenzopyrene. Carcinogenesis 4, 353-355.
    • (1983) Carcinogenesis , vol.4 , pp. 353-355
    • Howard, P.C.1    Gerard, J.A.2    Milo, C.E.3    Fu, P.P.4    Beland, F.A.5
  • 20
    • 84965821854 scopus 로고
    • Oxidative metabolism of 1 -nitropyrene by rabbit liver microsomes and purified microsomal cytochrome P-450 isozymes
    • Howard, P. C., Reed, K. A., and Koop, D. R. (1988) Oxidative metabolism of 1 -nitropyrene by rabbit liver microsomes and purified microsomal cytochrome P-450 isozymes. Cancer Res. 48, 4261-4265.
    • (1988) Cancer Res. , vol.48 , pp. 4261-4265
    • Howard, P.C.1    Reed, K.A.2    Koop, D.R.3
  • 22
    • 3042700496 scopus 로고    scopus 로고
    • Bcl-2 inhibits tumor necrosis factor-α-mediated increase of glycolytic enzymatic activities and enhances pyruvate carboxylase activity
    • Kim, Y H. and Kim, S. S. (2003) Bcl-2 inhibits tumor necrosis factor-α-mediated increase of glycolytic enzymatic activities and enhances pyruvate carboxylase activity. Mol. Cells 16, 67-73.
    • (2003) Mol. Cells , vol.16 , pp. 67-73
    • Kim, Y.H.1    Kim, S.S.2
  • 23
    • 0023008797 scopus 로고
    • Metabolic activation of 1-nitropyrene and 1,6-dinitropyrene by nitroreductase from Bacteroides fragilis and distribution of nitroreductase activity in rats
    • Kinouchi, T. and Ohnishi, Y. (1986) Metabolic activation of 1-nitropyrene and 1,6-dinitropyrene by nitroreductase from Bacteroides fragilis and distribution of nitroreductase activity in rats. Microbiol. Immunol. 30, 979-992.
    • (1986) Microbiol. Immunol. , vol.30 , pp. 979-992
    • Kinouchi, T.1    Ohnishi, Y.2
  • 24
    • 0022885599 scopus 로고
    • Detection of 1-nitropyrene in yakitori (grilled chicken)
    • Kinouchi, T., Tsutsui, H., and Ohnishi, Y. (1986) Detection of 1-nitropyrene in yakitori (grilled chicken). Mutat. Res. 171, 105-113.
    • (1986) Mutat. Res. , vol.171 , pp. 105-113
    • Kinouchi, T.1    Tsutsui, H.2    Ohnishi, Y.3
  • 25
    • 0037975747 scopus 로고    scopus 로고
    • Mutations induced by 1,3-butadiene metabolites, butadiene diolepoxide and 1,2,3,4-diepoxybutane, at the hprt locus in CHO-K1 cells
    • Lee, D.-H., Kim, T.-H., Lee, S.-Y., Kim, H.-J., Rhee, S. K., et al. (2002) Mutations induced by 1,3-butadiene metabolites, butadiene diolepoxide and 1,2,3,4-diepoxybutane, at the hprt locus in CHO-K1 cells. Mol. Cells 14, 411-419.
    • (2002) Mol. Cells , vol.14 , pp. 411-419
    • Lee, D.-H.1    Kim, T.-H.2    Lee, S.-Y.3    Kim, H.-J.4    Rhee, S.K.5
  • 26
    • 0020697480 scopus 로고
    • The 1-nitropyrene reductase of Salmonella typhimurium
    • Lu, C., McCalla, D. R., and McCarry, B. E. (1983) The 1-nitropyrene reductase of Salmonella typhimurium. Chem. Biol. Interact. 43, 67-71.
    • (1983) Chem. Biol. Interact. , vol.43 , pp. 67-71
    • Lu, C.1    McCalla, D.R.2    McCarry, B.E.3
  • 27
    • 0027994418 scopus 로고
    • Kinds and locations of mutations induced in the hypoxanthine-guanine phosphoribosyltransferase gene of human T-lymphocytes by 1-nitrosopyrene, including those caused by V(D)J recombinase
    • McGregor, W. G., Mahar, V. M., and McCormick, J. J. (1994) Kinds and locations of mutations induced in the hypoxanthine-guanine phosphoribosyltransferase gene of human T-lymphocytes by 1-nitrosopyrene, including those caused by V(D)J recombinase. Cancer Res. 54, 4207-4213.
    • (1994) Cancer Res. , vol.54 , pp. 4207-4213
    • McGregor, W.G.1    Mahar, V.M.2    McCormick, J.J.3
  • 28
    • 0028178052 scopus 로고
    • Defective splicing induced by 4NQO in the hamster hprt gene
    • Menichini, P., Inga, A., Fronza, G., Iannone, R., Degan, P., et al. (1994) Defective splicing induced by 4NQO in the hamster hprt gene. Mutat. Res. 323, 159-165.
    • (1994) Mutat. Res. , vol.323 , pp. 159-165
    • Menichini, P.1    Inga, A.2    Fronza, G.3    Iannone, R.4    Degan, P.5
  • 29
    • 0018677062 scopus 로고
    • Mutagenicity of metal cations in cultured cells from Chinese hamster
    • Miyaki, M., Akamatsu, N., Ono, T., and Koyama, H. (1979) Mutagenicity of metal cations in cultured cells from Chinese hamster. Mutat. Res. 68, 259-263.
    • (1979) Mutat. Res. , vol.68 , pp. 259-263
    • Miyaki, M.1    Akamatsu, N.2    Ono, T.3    Koyama, H.4
  • 30
    • 0021061819 scopus 로고
    • Rapid colorimetic assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann, T. (1983) Rapid colorimetic assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 31
    • 0030944206 scopus 로고    scopus 로고
    • Model for XPC-independent transcription-coupled repair of pyrimidine dimers in human
    • Mu, D. and Sancar, A. (1997) Model for XPC-independent transcription-coupled repair of pyrimidine dimers in human. J. Biol. Chem. 272, 7570-7573.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7570-7573
    • Mu, D.1    Sancar, A.2
  • 32
    • 0026523150 scopus 로고
    • DNA sequence analysis of 1-nitrosopyrene-induced mutations in the hprt gene of Chinese hamster ovary cells
    • Newton, R. K., Mittelstaedt, R. A., Manjanatha, M., and Heflich, R. H. (1992) DNA sequence analysis of 1-nitrosopyrene-induced mutations in the hprt gene of Chinese hamster ovary cells. Carcinogenesis 13, 819-825.
    • (1992) Carcinogenesis , vol.13 , pp. 819-825
    • Newton, R.K.1    Mittelstaedt, R.A.2    Manjanatha, M.3    Heflich, R.H.4
  • 33
    • 0020030488 scopus 로고
    • Carcinogenicity in rats of the mutagenic compounds 1-nitropyrene and 3-nitriofluoranthene
    • Ohgaki, H., Matsukura, N., Morino, K., Kawachi, T., Sugimura, T., et al. (1982) Carcinogenicity in rats of the mutagenic compounds 1-nitropyrene and 3-nitriofluoranthene. Cancer Lett. 15, 1-7.
    • (1982) Cancer Lett. , vol.15 , pp. 1-7
    • Ohgaki, H.1    Matsukura, N.2    Morino, K.3    Kawachi, T.4    Sugimura, T.5
  • 34
    • 0006564156 scopus 로고
    • Nitro compounds in environmental mixtures and foods
    • Waters, M. D., Sandhu, S. S., Lewtas, J., Claxton, L., Strauss, G, and Nesnow, S. (eds.), IV. Plenum, New York
    • Ohnishi, Y., Kinouchi, T., Manabe, Y., Tsutsui, H., Otsuka, H., et al. (1985) Nitro compounds in environmental mixtures and foods; in Short-Term Bioassay in the Analysis of Complex Environmental Mixtures, Waters, M. D., Sandhu, S. S., Lewtas, J., Claxton, L., Strauss, G, and Nesnow, S. (eds.), IV. Plenum, pp. 195-204, New York.
    • (1985) Short-Term Bioassay in the Analysis of Complex Environmental Mixtures , pp. 195-204
    • Ohnishi, Y.1    Kinouchi, T.2    Manabe, Y.3    Tsutsui, H.4    Otsuka, H.5
  • 35
    • 0020579803 scopus 로고
    • Mutagenicity and genotoxicity of nitroarenes, all nitre-containing chemicals were not created equal
    • Rosenkranz, H. S. and Mermelstein, R. (1983) Mutagenicity and genotoxicity of nitroarenes, all nitre-containing chemicals were not created equal. Mutat. Res. 114, 217-267.
    • (1983) Mutat. Res. , vol.114 , pp. 217-267
    • Rosenkranz, H.S.1    Mermelstein, R.2
  • 36
    • 0019230518 scopus 로고
    • Nitropyrenes: Isolation, identification, and reduction of mutagenic impurities in carbon black and toners
    • Rosenkranz, H. S., McCoy, E. C., Sander, D. R., Buitier, M., Kinazides, D. K., et al. (1980) Nitropyrenes: isolation, identification, and reduction of mutagenic impurities in carbon black and toners. Science 209, 1039-1043.
    • (1980) Science , vol.209 , pp. 1039-1043
    • Rosenkranz, H.S.1    McCoy, E.C.2    Sander, D.R.3    Buitier, M.4    Kinazides, D.K.5
  • 37
    • 0027905034 scopus 로고
    • Molecular mechanism of transcription-repair coupling
    • Selby, C. P. and Sancar, A. (1993) Molecular mechanism of transcription-repair coupling. Science 260, 53-58.
    • (1993) Science , vol.260 , pp. 53-58
    • Selby, C.P.1    Sancar, A.2
  • 38
    • 0026442730 scopus 로고
    • Cytochrome P-450 3A4 (nifedipine oxidase) is responsible for the C-oxidative metabolism of 1-nitropyrene in human microsomal samples
    • Silvers, K. J., Chazinski, T., McManus, M. E., Bauer, S. L., Gonzalez, F. J., et al. (1992) Cytochrome P-450 3A4 (nifedipine oxidase) is responsible for the C-oxidative metabolism of 1-nitropyrene in human microsomal samples. Cancer Res. 52, 6237-6243.
    • (1992) Cancer Res. , vol.52 , pp. 6237-6243
    • Silvers, K.J.1    Chazinski, T.2    McManus, M.E.3    Bauer, S.L.4    Gonzalez, F.J.5
  • 39
    • 0021923072 scopus 로고
    • Evidence for N-(deoxyguanosin-8-yl)-1-aminopyrene as a major DNA adduct in female rats treated with 1-nitropyrene
    • Stanton, C. A., Chow, F. L., Phillips, D. H., Grover, P. L., Garner, R. C., et al. (1985) Evidence for N-(deoxyguanosin-8-yl)-1-aminopyrene as a major DNA adduct in female rats treated with 1-nitropyrene. Carcinogenesis 6, 535-538.
    • (1985) Carcinogenesis , vol.6 , pp. 535-538
    • Stanton, C.A.1    Chow, F.L.2    Phillips, D.H.3    Grover, P.L.4    Garner, R.C.5
  • 40
    • 0025934810 scopus 로고
    • S-9 mediated metabolism of 1-nitropyrene to a mutagen in Chinese hamster ovary cells by ring-oxidation under aerobic conditions and nitroreduction under anaerobic condition
    • Thornton-manning, J. R., Smith, B. A., Beland, F. A., and Heflich, R. H. (1991) S-9 mediated metabolism of 1-nitropyrene to a mutagen in Chinese hamster ovary cells by ring-oxidation under aerobic conditions and nitroreduction under anaerobic condition. Carcinogenesis 12, 2317-2323.
    • (1991) Carcinogenesis , vol.12 , pp. 2317-2323
    • Thornton-manning, J.R.1    Smith, B.A.2    Beland, F.A.3    Heflich, R.H.4
  • 41
    • 0022994152 scopus 로고
    • Fibroblasts from patients with inherited predisposition to retinoblastoma exhibit normal sensitivity to the mutagenic effects of ionizing radiation
    • Wang, Y., Parks, W. C., Wigle, J. C., Maher, V. M., and McCormick, J. J. (1986) Fibroblasts from patients with inherited predisposition to retinoblastoma exhibit normal sensitivity to the mutagenic effects of ionizing radiation. Mutat. Res. 175, 107-114.
    • (1986) Mutat. Res. , vol.175 , pp. 107-114
    • Wang, Y.1    Parks, W.C.2    Wigle, J.C.3    Maher, V.M.4    McCormick, J.J.5
  • 42
    • 0027160625 scopus 로고
    • Dose-dependent differences in the profile of mutations induced by (+)-7R, 8S-dihydroxy-9S, 10R-epoxy-7, 8, 9, 10-tetrahydrobenzo(a)pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in Chinese hamster V-79 cells
    • Wei, S.-J. C., Chang, R. L., Bhachech, N., Cui, X. X., Merkler, K. A., et al. (1993) Dose-dependent differences in the profile of mutations induced by (+)-7R, 8S-dihydroxy-9S, 10R-epoxy-7, 8, 9, 10-tetrahydrobenzo(a)pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in Chinese hamster V-79 cells. Cancer Res. 53, 3294-3301.
    • (1993) Cancer Res. , vol.53 , pp. 3294-3301
    • Wei, S.-J.C.1    Chang, R.L.2    Bhachech, N.3    Cui, X.X.4    Merkler, K.A.5
  • 43
    • 0022759286 scopus 로고
    • Tumorigenicity of nitrated derivatives of pyrene, benz[a]anthracene, chrysene and benzo[a]pyrene in the newborn mouse assay
    • Wislocki, P. G., Bagan, E. S., Lu, A. Y., Dooley, K. L., Fu, P. P., et al. (1986) Tumorigenicity of nitrated derivatives of pyrene, benz[a]anthracene, chrysene and benzo[a]pyrene in the newborn mouse assay. Carcinogenesis 7, 1317-1322.
    • (1986) Carcinogenesis , vol.7 , pp. 1317-1322
    • Wislocki, P.G.1    Bagan, E.S.2    Lu, A.Y.3    Dooley, K.L.4    Fu, P.P.5
  • 44
    • 0023815179 scopus 로고
    • Kinds and spectrum of mutations induced by 1-nitropyrene adducts during plasmid replication in human cells
    • Yang, J.-L., Maher, V. M., and McCormick, J. J. (1988) Kinds and spectrum of mutations induced by 1-nitropyrene adducts during plasmid replication in human cells. Mol. Cell. Biol. 8, 3364-3372.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3364-3372
    • Yang, J.-L.1    Maher, V.M.2    McCormick, J.J.3
  • 45
    • 0025866810 scopus 로고
    • Novel mutational spectrum induced by N-methyl-N'-nitro-N-nitrosoguanidine in the coding region of the HPRT gene in diploid human fibroblasts
    • Yang, J.-L., Hu, M.-C., and Wu, C.-W. (1991) Novel mutational spectrum induced by N-methyl-N'-nitro-N-nitrosoguanidine in the coding region of the HPRT gene in diploid human fibroblasts. J. Mol. Biol. 22, 421-430.
    • (1991) J. Mol. Biol. , vol.22 , pp. 421-430
    • Yang, J.-L.1    Hu, M.-C.2    Wu, C.-W.3
  • 46
    • 0026476170 scopus 로고
    • Mutational specificity of chromium (VI) compounds in the hprt locus Chinese hamster ovary-K1 cells
    • Yang, J.-L., Hsieh, Y.-C., Wu, C.-W., and Lee, T.-C. (1992) Mutational specificity of chromium (VI) compounds in the hprt locus Chinese hamster ovary-K1 cells. Carcinogenesis 13, 2053-2057.
    • (1992) Carcinogenesis , vol.13 , pp. 2053-2057
    • Yang, J.-L.1    Hsieh, Y.-C.2    Wu, C.-W.3    Lee, T.-C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.