Regulation of MAPK signaling in yeast

Topics in Current Genetics

Volumn 20, Issue , 2008, Pages 187-204

  Rudolf, Fabian ^a   Pelet, Serge ^a   Peter, Matthias ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 38649142482     PISSN: 16102096     EISSN: 16106970     Source Type: Book Series    
DOI: 10.1007/4735_2007_0250     Document Type: Review

References (45)

1. Bell M, Capone R, Pashtan I, Levitzki A, Engelberg D (2001) Isolation of hyperactive mutants of the MAPK p38/Hog1 that are independent of MAPK kinase activation. J Biol Chem 276:25351-25358
2. Bell M, Engelberg D (2003) Phosphorylation of Tyr-176 of the yeast MAPK Hog1/p38 is not vital for Hog1 biological activity. J Biol Chem 278:14603-14606
3. Bhattacharyya RP, Remenyi A, Good MC, Bashor CJ, Falick AM, Lim WA (2006) The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway. Science 311:822-826
4. Chasse SA, Flanary P, Parnell SC, Hao N, Cha JY, Siderovski DP, Dohlman HG (2006) Genome-scale analysis reveals Sst2 as the principal regulator of mating pheromone signaling in the yeast Saccharomyces cerevisiae Eukaryot Cell 5:330-346
5. Choi KY, Satterberg B, Lyons DM, Elion EA (1994) Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae. Cell 78:499-512
6. Colman-Lerner A, Gordon A, Serra E, Chin T, Resnekov O, Endy D, Pesce CG, Brent R (2005) Regulated cell-to-cell variation in a cell-fate decision system. Nature 437:699-706
7. Dohlman HG, Thorner JW (2001) Regulation of G protein-initiated signal transduction in yeast: Paradigms and principles. Annu Rev Biochem 70:703-754
8. Doi K, Gartner A, Ammerer G, Errede B, Shinkawa H, Sugimoto K, Matsumoto K (1994) MSG5, a novel protein phosphatase promotes adaptation to pheromone response in S. cerevisiae. Embo J 13:61-70
9. Drogen F, O'Rourke SM, Stucke VM, Jaquenoud M, Neiman AM, Peter M (2000) Phosphorylation of the MEKK Ste11p by the PAK-like kinase Ste20p is required for MAP kinase signaling in vivo. Curr Biol 10:630-639
10. Elion EA (2001) The Ste5p scaffold. J Cell Sci 114:3967-3978
11. Esch RK, Errede B (2002) Pheromone induction promotes Ste11 degradation through a MAPK feedback and ubiquitin-dependent mechanism. Proc Natl Acad Sci USA 99:9160-9165
12. Garrenton LS, Young SL, Thorner J (2006) Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain. Genes Dev 20:1946-1958
13. Gasch AP, Spellman PT, Kao CM, Carmel-Harel O, Eisen MB, Storz G, Botstein D, Brown PO (2000) Genomic expression programs in the response of yeast cells to environmental changes. Mol Biol Cell 11:4241-4257
14. Hao N, Behar M, Parnell SC, Torres MP, Borchers CH, Elston TC, Dohlman HG (2007) A systems-biology analysis of feedback inhibition in the Sho1 osmotic-stress-response pathway. Curr Biol 17:659-667
15. Hartwell LH (1980) Mutants of Saccharomyces cerevisiae unresponsive to cell division control by polypeptide mating hormone. J Cell Biol 85:811-822
16. Heinrich M, Köhler T, Mösch HU (2006) Role of the Cdc42-Cla4 interaction in the, pheromone response of Saccharomyces cerevisiae Eukaryot Cell 6:317-327
17. Hicke L, Riezman H (1996) Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis. Cell 84:277-287
18. Hohmann S (2002) Osmotic stress signaling and osmoadaptation in yeasts. Microbiol Mol Biol Rev 66:300-372
19. Huang CY, Ferrell JE Jr (1996) Ultrasensitivity in the mitogen-activated protein kinase cascade. Proc Natl Acad Sci USA 93:10078-10083
20. Inouye C, Dhillon N, Thorner J (1997) Ste5 RING-H2 domain: Role in Ste4-promoted oligomerization for yeast pheromone signaling. Science 278:103-106
21. Jacoby T, Flanagan H, Faykin A, Seto AG, Mattison C, Ota I (1997) Two protein-tyrosine phosphatases inactivate the osmotic stress response pathway in yeast by targeting the mitogen-activated protein kinase, Hog1. J Biol Chem 272:17749-17755
22. Lamson RE, Takahashi S, Winters MJ, Pryciak PM (2006) Dual role for membrane localization in yeast MAP kinase cascade activation and its contribution to signaling fidelity. Curr Biol 16:618-623
23. O'Rourke SM, Herskowitz I (1998) The Hog1 MAPK prevents cross talk between the HOG and pheromone response MAPK pathways in Saccharomyces cerevisiae. Genes Dev 12:2874-2886
24. Oehlen LJ, Cross FR (1994) G1 cyclins CLN1 and CLN2 repress the mating factor response pathway at Start in the yeast cell cycle. Genes Dev 8:1058-1070
25. Oehlen LJ, Cross FR (1998) Potential regulation of Ste20 function by the Cln1-Cdc28 and Cln2-Cdc28 cyclin-dependent protein kinases. J Biol Chem 273:25089-25097
26. Park SH, Zarrinpar A, Lim WA (2003) Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms. Science 299:1061-1064
27. Pokholok DK, Zeitlinger J, Hannett NM, Reynolds DB, Young RA (2006) Activated signal transduction kinases frequently occupy target genes. Science 313:533-536
28. Posas F, Saito H (1997) Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: Scaffold role of Pbs2p MAPKK. Science 276:1702-1705
29. Posas F, Wurgler-Murphy SM, Maeda T, Witten EA, Thai TC, Saito H (1996) Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 "two-component" osmosensor. Cell 86:865-875
30. Proft M, Mas G, de Nadal E, Vendrell A, Noriega N, Struhl K, Posas F (2006) The stress-activated Hog1 kinase is a selective transcriptional elongation factor for genes responding to osmotic stress. Mol Cell 23:241-250
31. Reiser V, Ruis H, Ammerer G (1999) Kinase activity-dependent nuclear export opposes stress-induced nuclear accumulation and retention of Hog1 mitogen-activated protein kinase in the budding yeast Saccharomyces cerevisiae. Mol Biol 10: 1147-1161
32. Reiser V, Salah SM, Ammerer G (2000) Polarized localization of yeast Pbs2 depends on osmostress, the membrane protein Sho1 and Cdc42. Nat Cell Biol 2:620-627
33. Remenyi A, Good MC, Lim WA (2006) Docking interactions in protein kinase and phosphatase networks. Curr Opin Struct Biol 16:676-685
34. Roberts CJ, Nelson B, Marton MJ, Stoughton R, Meyer MR, Bennett HA, He YD, Dai H, Walker WL, Hughes TR, Tyers M, Boone C, Friend SH (2000) Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles. Science 287:873-880
35. Zerber Z, Ferrell JE Jr (2007) Tuning bulk electrostatics to regulate protein function. Cell 128:441-444
36. Sette C, Inouye CJ, Stroschein SL, Iaquinta PJ, Thorner J (2000) Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 scaffold protein. Mol Biol Cell 11:4033-4049
37. Strickfaden SC, Winters MJ, Ben-Ari G, Lamson RE, Tyers M, Pryciak PM (2007) A mechanism for cell-cycle regulation of MAP kinase signaling in a yeast differentiation pathway. Cell 128:519-531
38. Tatebayashi K, Yamamoto K, Tanaka K, Tomida T, Maruoka T, Kasukawa E, Saito H (2006) Adaptor functions of Cdc42, Ste50, and Sho1 in the yeast osmoregulatory HOG MAPK pathway. Embo J 25:3033-3044
39. van Drogen F, Stucke VM, Jorritsma G, Peter M (2001) MAP kinase dynamics in response to pheromones in budding yeast. Nat Cell Biol 3:1051-1059
40. Wang Y, Ge Q, Houston D, Thorner J, Errede B, Dohlman HG (2003) Regulation of Ste7 ubiquitination by Ste11 phosphorylation and the Skp1-Cullin-F-box complex. J Biol Chem 278:22284-22289
41. Wassmann K, Ammerer G (1997) Overexpression of the G1-cyclin gene CLN2 represses the mating pathway in Saccharomyces cerevisiae at the level of the MEKK Ste11. J Biol Chem 272:13180-13188
42. Westfall PJ, Thorner J (2006) Analysis of mitogen-activated protein kinase signaling specificity in response to hyperosmotic stress: Use of an analog-sensitive HOG1 allele. Eukaryot Cell 5:1215-1228
43. Winters MJ, Lamson RE, Nakanishi H, Neiman AM, Pryciak PM (2005) A membrane binding domain in the ste5 scaffold synergizes with gbetagamma binding to control localization and signaling in pheromone response. Mol Cell 20:21-32
44. Wurgler-Murphy SM, Maeda T, Witten EA, Saito H (1997) Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases. Mol Cell Biol 17:1289-1297
45. Zarrinpar A, Bhattacharyya RP, Nittler MP, Lim WA (2004) Sho1 and Pbs2 act as coscaffolds linking components in the yeast high osmolarity MAP kinase pathway. Mol Cell 14:825-832