메뉴 건너뛰기




Volumn 55, Issue 6, 2007, Pages 821-837

Antibodies to oxidized low density lipoprotein: Epidemiological studies and potential clinical applications in cardiovascular disease

Author keywords

Antibodies; Cardiovascular diseases; LDL; Lipoproteins

Indexed keywords

ANTIBODY; AUTOANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LOW DENSITY LIPOPROTEIN;

EID: 38649095192     PISSN: 00264725     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (70)

References (119)
  • 1
    • 0035936802 scopus 로고    scopus 로고
    • Atherosclerosis, the road ahead
    • Glass CK, Witztum JL. Atherosclerosis, the road ahead. Cell 2001;104:503-16.
    • (2001) Cell , vol.104 , pp. 503-516
    • Glass, C.K.1    Witztum, J.L.2
  • 2
    • 0022549920 scopus 로고
    • A receptor-mediated pathway for cholesterol homeostasis
    • Brown MS, Goldstein JL. A receptor-mediated pathway for cholesterol homeostasis. Science 1986;232:34-47.
    • (1986) Science , vol.232 , pp. 34-47
    • Brown, M.S.1    Goldstein, J.L.2
  • 3
    • 0024603895 scopus 로고
    • Beyond cholesterol: Modifications of low-density lipoprotein that Increase its atherogenicity
    • Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol: Modifications of low-density lipoprotein that Increase its atherogenicity. New Engl J Med 1989;320:915-24.
    • (1989) New Engl J Med , vol.320 , pp. 915-924
    • Steinberg, D.1    Parthasarathy, S.2    Carew, T.E.3    Khoo, J.C.4    Witztum, J.L.5
  • 6
    • 0021691725 scopus 로고
    • Immunogenicity of homologous low density lipoprotein after methylation, ethylation, acetylation, or carbamylation: Generation of antibodies specific for derivatized lysine
    • Steinbrecher UP, Fisher M, Witztum JL, Curtiss LK. Immunogenicity of homologous low density lipoprotein after methylation, ethylation, acetylation, or carbamylation: generation of antibodies specific for derivatized lysine. J Lipid Res 1984;25:1109-16.
    • (1984) J Lipid Res , vol.25 , pp. 1109-1116
    • Steinbrecher, U.P.1    Fisher, M.2    Witztum, J.L.3    Curtiss, L.K.4
  • 8
    • 0024439446 scopus 로고
    • Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man
    • Yla-Herttuala S, Palinski W, Rosenfeld ME, Parthasarathy S, Carew TE, Butler S et al. Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man. J Clin Invest 1989;84:1086-95.
    • (1989) J Clin Invest , vol.84 , pp. 1086-1095
    • Yla-Herttuala, S.1    Palinski, W.2    Rosenfeld, M.E.3    Parthasarathy, S.4    Carew, T.E.5    Butler, S.6
  • 9
    • 0036720318 scopus 로고    scopus 로고
    • The fetal origins of atherosclerosis: Maternal hypercholesterolemia, and cholesterol-lowering or antioxidant treatment during pregnancy influence in utero programming and postnatal susceptibility to atherogenesis
    • Palinski W, Napoli C. The fetal origins of atherosclerosis: maternal hypercholesterolemia, and cholesterol-lowering or antioxidant treatment during pregnancy influence in utero programming and postnatal susceptibility to atherogenesis. FASEB J 2002;16:1348-60.
    • (2002) FASEB J , vol.16 , pp. 1348-1360
    • Palinski, W.1    Napoli, C.2
  • 10
    • 0029097852 scopus 로고
    • Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor-deficient mice with increased atherosclerosis
    • Palinski W, Tangirala RK, Miller E, Young SG, Witztum JL. Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor-deficient mice with increased atherosclerosis. Arterioscler Thromb Vasc Biol 1995;15:1569-76.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 1569-1576
    • Palinski, W.1    Tangirala, R.K.2    Miller, E.3    Young, S.G.4    Witztum, J.L.5
  • 11
    • 0035170772 scopus 로고    scopus 로고
    • Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptor-deficient mice
    • Tsimikas S, Palinski W, Witztum JL. Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol 2001;21:95-100.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 95-100
    • Tsimikas, S.1    Palinski, W.2    Witztum, J.L.3
  • 12
    • 0035901582 scopus 로고    scopus 로고
    • Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes
    • Ehara S, Ueda M, Naruko T, Haze K, Itoh A, Otsuka M et al. Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes. Circulation 2001;103:1955-60.
    • (2001) Circulation , vol.103 , pp. 1955-1960
    • Ehara, S.1    Ueda, M.2    Naruko, T.3    Haze, K.4    Itoh, A.5    Otsuka, M.6
  • 14
    • 0033033340 scopus 로고    scopus 로고
    • Radiolabeled MDA2, an oxidation-specific, monoclonal antibody, identifies native atherosclerotic lesions in vivo
    • Tsimikas S, Palinski W, Halpern SE, Yeung DW, Curtiss LK, Witztum JL. Radiolabeled MDA2, an oxidation-specific, monoclonal antibody, identifies native atherosclerotic lesions in vivo. J Nucl Cardiol 1999;6:41-53.
    • (1999) J Nucl Cardiol , vol.6 , pp. 41-53
    • Tsimikas, S.1    Palinski, W.2    Halpern, S.E.3    Yeung, D.W.4    Curtiss, L.K.5    Witztum, J.L.6
  • 15
    • 10644252010 scopus 로고    scopus 로고
    • Reduced in vivo aortic uptake of radiolabeled oxidation-specific antibodies reflects changes in plaque composition consistent with plaque stabilization
    • Torzewski M, Shaw PX, Han KR, Shortal B, Lackner KJ, Witztum JL et al. Reduced in vivo aortic uptake of radiolabeled oxidation-specific antibodies reflects changes in plaque composition consistent with plaque stabilization. Arterioscler Thromb Vasc Biol 2004;24:2307-12.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 2307-2312
    • Torzewski, M.1    Shaw, P.X.2    Han, K.R.3    Shortal, B.4    Lackner, K.J.5    Witztum, J.L.6
  • 16
    • 0033372489 scopus 로고    scopus 로고
    • Oxidants and antioxidants in atherogenesis. An appraisal
    • In Process Citation
    • Parthasarathy S, Santanam N, Ramachandran S, Meilhac O. Oxidants and antioxidants in atherogenesis. An appraisal [In Process Citation]. J Lipid Res 1999;40:2143-57.
    • (1999) J Lipid Res , vol.40 , pp. 2143-2157
    • Parthasarathy, S.1    Santanam, N.2    Ramachandran, S.3    Meilhac, O.4
  • 17
    • 0025310826 scopus 로고
    • Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein
    • Palinski W, Ylä-Herttuala S, Rosenfeld ME, Butler SW, Socher SA, Parthasarathy S et al. Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein. Arteriosclerosis 1990;10:325-35.
    • (1990) Arteriosclerosis , vol.10 , pp. 325-335
    • Palinski, W.1    Ylä-Herttuala, S.2    Rosenfeld, M.E.3    Butler, S.W.4    Socher, S.A.5    Parthasarathy, S.6
  • 18
    • 0034035885 scopus 로고    scopus 로고
    • Immune responses to oxidative neoepitopes on LDL and phospholipids modulate the development of atherosclerosis
    • Palinski W, Witztum JL. Immune responses to oxidative neoepitopes on LDL and phospholipids modulate the development of atherosclerosis. J Intern Med 2000;247:371-80.
    • (2000) J Intern Med , vol.247 , pp. 371-380
    • Palinski, W.1    Witztum, J.L.2
  • 21
    • 0038445605 scopus 로고    scopus 로고
    • Lipoprotein autoantibodies: Measurement and significance
    • Virella G, Lopes-Virella MF. Lipoprotein autoantibodies: Measurement and significance. Clin Diagn Lab Immunol 2003;10:499.
    • (2003) Clin Diagn Lab Immunol , vol.10 , pp. 499
    • Virella, G.1    Lopes-Virella, M.F.2
  • 22
    • 33744969769 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein autoantibodies, chronic infections, and carotid atherosclerosis in a population-based study
    • Mayr M, Kiechl S, Tsimikas S, Miller E, Sheldon J, Willeit J et al. Oxidized low-density lipoprotein autoantibodies, chronic infections, and carotid atherosclerosis in a population-based study. J Am Coll Cardiol 2006;47:2436-43.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 2436-2443
    • Mayr, M.1    Kiechl, S.2    Tsimikas, S.3    Miller, E.4    Sheldon, J.5    Willeit, J.6
  • 23
    • 33646190667 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein in children with familial hypercholesterolemia and unaffected siblings: Effect of pravastatin
    • Rodenburg J, Vissers MN, Wiegman A, Miller ER, Ridker PM, Witztum JL et al. Oxidized low-density lipoprotein in children with familial hypercholesterolemia and unaffected siblings: effect of pravastatin. J Am Coll Cardiol 2006;47:1803-10.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 1803-1810
    • Rodenburg, J.1    Vissers, M.N.2    Wiegman, A.3    Miller, E.R.4    Ridker, P.M.5    Witztum, J.L.6
  • 24
    • 38649132983 scopus 로고    scopus 로고
    • Relationship of IgM and IgG autoantibodies to oxidized low density lipoprotein and apolipoprotein B100-immune complexes with angiographically determined coronary artery disease and cardiovascular events
    • Tsimikas S, Brilakis ES, Lennon RJ, Miller ER, Witztum JL, McConnell JP et al. Relationship of IgM and IgG autoantibodies to oxidized low density lipoprotein and apolipoprotein B100-immune complexes with angiographically determined coronary artery disease and cardiovascular events. J Lipid Res 2006.
    • (2006) J Lipid Res
    • Tsimikas, S.1    Brilakis, E.S.2    Lennon, R.J.3    Miller, E.R.4    Witztum, J.L.5    McConnell, J.P.6
  • 25
    • 0032951483 scopus 로고    scopus 로고
    • Antibodies to oxidized LDL and LDL-containing immune complexes as risk factors for coronary artery disease in diabetes mellitus
    • Lopes-Virella MF, Virella G, Orchard TJ, Koskinen S, Evans RW, Becker DJ et al. Antibodies to oxidized LDL and LDL-containing immune complexes as risk factors for coronary artery disease in diabetes mellitus. Clin Immunol 1999;90:165-72.
    • (1999) Clin Immunol , vol.90 , pp. 165-172
    • Lopes-Virella, M.F.1    Virella, G.2    Orchard, T.J.3    Koskinen, S.4    Evans, R.W.5    Becker, D.J.6
  • 26
    • 0033990553 scopus 로고    scopus 로고
    • Inverse relationship between circulating oxidized low density lipoprotein (oxLDL) and anti-oxLDL antibody levels in healthy subjects
    • Shoji T, Nishizawa Y, Fukumoto M, Shimamura K, Kimura J, Kanda H et al. Inverse relationship between circulating oxidized low density lipoprotein (oxLDL) and anti-oxLDL antibody levels in healthy subjects. Atherosclerosis 2000;148:171-7.
    • (2000) Atherosclerosis , vol.148 , pp. 171-177
    • Shoji, T.1    Nishizawa, Y.2    Fukumoto, M.3    Shimamura, K.4    Kimura, J.5    Kanda, H.6
  • 27
    • 4544346640 scopus 로고    scopus 로고
    • High-dose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein B-100 in patients with acute coronary syndromes in the MIRACL trial
    • Tsimikas S, Witztum JL, Miller ER, Sasiela WJ, Szarek M, Olsson AG et al. High-dose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein B-100 in patients with acute coronary syndromes in the MIRACL trial. Circulation 2004;110:1406-12.
    • (2004) Circulation , vol.110 , pp. 1406-1412
    • Tsimikas, S.1    Witztum, J.L.2    Miller, E.R.3    Sasiela, W.J.4    Szarek, M.5    Olsson, A.G.6
  • 28
    • 33748153794 scopus 로고    scopus 로고
    • Measures of oxidative stress
    • Tsimikas S. Measures of oxidative stress. Clin Lab Med 2006;26:571-90.
    • (2006) Clin Lab Med , vol.26 , pp. 571-590
    • Tsimikas, S.1
  • 29
    • 3042613703 scopus 로고    scopus 로고
    • Autoantibodies to OxLDL fail to alter the clearance of injected OxLDL in apolipoprotein E-deficient mice
    • Reardon CA, Miller ER, Blachowicz L, Lukens J, Binder CJ, Witztum JL et al. Autoantibodies to OxLDL fail to alter the clearance of injected OxLDL in apolipoprotein E-deficient mice. J Lipid Res 2004;45:1347-54.
    • (2004) J Lipid Res , vol.45 , pp. 1347-1354
    • Reardon, C.A.1    Miller, E.R.2    Blachowicz, L.3    Lukens, J.4    Binder, C.J.5    Witztum, J.L.6
  • 30
    • 34247574624 scopus 로고    scopus 로고
    • Patients with early rheumatoid arthritis exhibit elevated autoantibody titers against mildly oxidized low-density lipoprotein and exhibit decreased activity of the lipoprotein-associated phospholipase A2
    • Lourida ES, Georgiadis AN, Papavasiliou EC, Papathanasiou AI, Drosos AA, Tselepis AD. Patients with early rheumatoid arthritis exhibit elevated autoantibody titers against mildly oxidized low-density lipoprotein and exhibit decreased activity of the lipoprotein-associated phospholipase A2. Arthritis Res Ther 2007;9:R19.
    • (2007) Arthritis Res Ther , vol.9
    • Lourida, E.S.1    Georgiadis, A.N.2    Papavasiliou, E.C.3    Papathanasiou, A.I.4    Drosos, A.A.5    Tselepis, A.D.6
  • 31
    • 34250374608 scopus 로고    scopus 로고
    • Short- and long-term elevation of autoantibody titers against oxidized LDL in patients with acute coronary syndromes Role of the lipoprotein-associated phospholipase A(2) and the effect of atorvastatin treatment
    • Papathanasiou AI, Lourida ES, Tsironis LD, Goudevenos JA, Tselepis AD. Short- and long-term elevation of autoantibody titers against oxidized LDL in patients with acute coronary syndromes Role of the lipoprotein-associated phospholipase A(2) and the effect of atorvastatin treatment. Atherosclerosis 2006.
    • (2006) Atherosclerosis
    • Papathanasiou, A.I.1    Lourida, E.S.2    Tsironis, L.D.3    Goudevenos, J.A.4    Tselepis, A.D.5
  • 32
    • 33747830793 scopus 로고    scopus 로고
    • The low-density lipoprotein (LDL)-associated PAF-acetylhydrolase activity and the extent of LDL oxidation are important determinants of the autoantibody titers against oxidized LDL in patients with coronary artery disease
    • Lourida ES, Papathanasiou AI, Goudevenos JA, Tselepis AD. The low-density lipoprotein (LDL)-associated PAF-acetylhydrolase activity and the extent of LDL oxidation are important determinants of the autoantibody titers against oxidized LDL in patients with coronary artery disease. Prostaglandins Leukot Essent Fatty Acids 2006;75:117-26.
    • (2006) Prostaglandins Leukot Essent Fatty Acids , vol.75 , pp. 117-126
    • Lourida, E.S.1    Papathanasiou, A.I.2    Goudevenos, J.A.3    Tselepis, A.D.4
  • 33
    • 0019425854 scopus 로고
    • Demonstration of immunoglobulin in the neighbourhood of advanced atherosclerotic plaques
    • Parums O, Mitchinson MJ. Demonstration of immunoglobulin in the neighbourhood of advanced atherosclerotic plaques. Arteriosclerosis 1981;38:211-6.
    • (1981) Arteriosclerosis , vol.38 , pp. 211-216
    • Parums, O.1    Mitchinson, M.J.2
  • 34
    • 0019193179 scopus 로고
    • Ultrastructural studies on the localization of IgG in the aortic endothelium and subendothelial intima of atherosclerotic and nonatherosclerotic rabbits
    • Hansson GK, Bondjers G, Bylock A, Hjalmarsson L. Ultrastructural studies on the localization of IgG in the aortic endothelium and subendothelial intima of atherosclerotic and nonatherosclerotic rabbits. Exp Mol Pathol 1980;33:302-15.
    • (1980) Exp Mol Pathol , vol.33 , pp. 302-315
    • Hansson, G.K.1    Bondjers, G.2    Bylock, A.3    Hjalmarsson, L.4
  • 35
    • 0024381339 scopus 로고
    • Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit
    • Boyd HC, Gown AM, Wolfbauer G, Chait A. Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit. Am J Pathol 1989;135:815-25.
    • (1989) Am J Pathol , vol.135 , pp. 815-825
    • Boyd, H.C.1    Gown, A.M.2    Wolfbauer, G.3    Chait, A.4
  • 36
    • 0023687897 scopus 로고
    • Malondialdehyde-altered protein occurs in atheroma of Watanabe heritable hyperlipidemic rabbits
    • Haberland ME, Fong D, Cheng L. Malondialdehyde-altered protein occurs in atheroma of Watanabe heritable hyperlipidemic rabbits. Science 1988;241:215-8.
    • (1988) Science , vol.241 , pp. 215-218
    • Haberland, M.E.1    Fong, D.2    Cheng, L.3
  • 37
    • 0025353845 scopus 로고
    • Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits
    • Rosenfeld ME, Palinski W, Ylä-Herttuala S, Butler S, Witztum JL. Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits. Arteriosclerosis 1990;10:336-49.
    • (1990) Arteriosclerosis , vol.10 , pp. 336-349
    • Rosenfeld, M.E.1    Palinski, W.2    Ylä-Herttuala, S.3    Butler, S.4    Witztum, J.L.5
  • 38
    • 0028198105 scopus 로고
    • ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum
    • Palinski W, Ord VA, Plump AS, Breslow JL, Steinberg D, Witztum JL. ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum. Arterioscler Thromb 1994;14:605-16.
    • (1994) Arterioscler Thromb , vol.14 , pp. 605-616
    • Palinski, W.1    Ord, V.A.2    Plump, A.S.3    Breslow, J.L.4    Steinberg, D.5    Witztum, J.L.6
  • 39
    • 0027519515 scopus 로고
    • Immunostaining of human autopsy aortas with antibodies to modified apolipoprotein B and apoprotein(a)
    • Jürgens G, Chen Q, Esterbauer H, Mair S, Ledinski G, Dinges HP. Immunostaining of human autopsy aortas with antibodies to modified apolipoprotein B and apoprotein(a). Arterioscler Thromb 1993;13:1689-99.
    • (1993) Arterioscler Thromb , vol.13 , pp. 1689-1699
    • Jürgens, G.1    Chen, Q.2    Esterbauer, H.3    Mair, S.4    Ledinski, G.5    Dinges, H.P.6
  • 41
    • 0034737582 scopus 로고    scopus 로고
    • The binding of oxidized low density lipoprotein to mouse CD36 is mediated in part by oxidized phospholipids that are associated with both the lipid and protein moieties of the lipoprotein
    • Boullier A, Gillotte KL, Hörkkö S, Green SR, Friedman P, Dennis EA et al. The binding of oxidized low density lipoprotein to mouse CD36 is mediated in part by oxidized phospholipids that are associated with both the lipid and protein moieties of the lipoprotein. J Biol Chem 2000;275:9163-9.
    • (2000) J Biol Chem , vol.275 , pp. 9163-9169
    • Boullier, A.1    Gillotte, K.L.2    Hörkkö, S.3    Green, S.R.4    Friedman, P.5    Dennis, E.A.6
  • 42
    • 0028862192 scopus 로고
    • Quantitation of atherosclerosis in murine models: Correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice
    • Tangirala RK, Rubin EM, Palinski W. Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice. J Lipid Res 1995;36:2320-8.
    • (1995) J Lipid Res , vol.36 , pp. 2320-2328
    • Tangirala, R.K.1    Rubin, E.M.2    Palinski, W.3
  • 43
    • 0032752579 scopus 로고    scopus 로고
    • Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice
    • Cyrus T, Witztum JL, Rader DJ, Tangirala R, Fazio S, Linton MF et al. Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice. J Clin Invest 1999;103:1597-604.
    • (1999) J Clin Invest , vol.103 , pp. 1597-1604
    • Cyrus, T.1    Witztum, J.L.2    Rader, D.J.3    Tangirala, R.4    Fazio, S.5    Linton, M.F.6
  • 44
    • 0035826892 scopus 로고    scopus 로고
    • Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein E-deficient mice
    • Cyrus T, Praticó D, Zhao L, Witztum JL, Rader DJ, Rokach J et al. Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein E-deficient mice. Circulation 2001;103:2277-82.
    • (2001) Circulation , vol.103 , pp. 2277-2282
    • Cyrus, T.1    Praticó, D.2    Zhao, L.3    Witztum, J.L.4    Rader, D.J.5    Rokach, J.6
  • 45
    • 0035863925 scopus 로고    scopus 로고
    • Circulating autoantibodies to oxidized cardiolipin correlate with isoprostane F(2alpha)-VI levels and the extent of atherosclerosis in ApoE-deficient mice: Modulation bv vitamin E
    • Pratico D, Tangirala RK, Horkko S, Witztum JL, Palinski W, FitzGerald GA. Circulating autoantibodies to oxidized cardiolipin correlate with isoprostane F(2alpha)-VI levels and the extent of atherosclerosis in ApoE-deficient mice: modulation bv vitamin E. Blood 2001;97:459-64.
    • (2001) Blood , vol.97 , pp. 459-464
    • Pratico, D.1    Tangirala, R.K.2    Horkko, S.3    Witztum, J.L.4    Palinski, W.5    FitzGerald, G.A.6
  • 46
    • 0032905706 scopus 로고    scopus 로고
    • Circulating antibodies recognizing oxidatively modified low-density lipoprotein in children
    • Iughetti L, Volta C, Maggi E, Palladini G, Perugini C, Bellomo G et al. Circulating antibodies recognizing oxidatively modified low-density lipoprotein in children. Pediatr Res 1999;45:94-9.
    • (1999) Pediatr Res , vol.45 , pp. 94-99
    • Iughetti, L.1    Volta, C.2    Maggi, E.3    Palladini, G.4    Perugini, C.5    Bellomo, G.6
  • 47
    • 0036105960 scopus 로고    scopus 로고
    • Increased levels of anti-oxidized low-density lipoprotein antibodies are associated with reduced levels of cholesterol in the general population
    • Tinahones FJ, Mez-Zumaquero JM, Rojo M, Cardona F, de Antonio IE, de Adana MSR et al. Increased levels of anti-oxidized low-density lipoprotein antibodies are associated with reduced levels of cholesterol in the general population. Metabolism 2002;51:429-31.
    • (2002) Metabolism , vol.51 , pp. 429-431
    • Tinahones, F.J.1    Mez-Zumaquero, J.M.2    Rojo, M.3    Cardona, F.4    de Antonio, I.E.5    de Adana, M.S.R.6
  • 48
    • 0038222531 scopus 로고    scopus 로고
    • Identification of immune responses against aldehyde-modified peptide sequences in apoB associated with cardiovascular disease
    • Fredrikson GN, Hedblad B, Berglund G, Alm R, Ares M, Cercek B et al. Identification of immune responses against aldehyde-modified peptide sequences in apoB associated with cardiovascular disease. Arterioscler Thromb Vasc Biol 2003;23:872-8.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 872-878
    • Fredrikson, G.N.1    Hedblad, B.2    Berglund, G.3    Alm, R.4    Ares, M.5    Cercek, B.6
  • 51
    • 0029929276 scopus 로고    scopus 로고
    • Autoantibody titers to oxidized low-density lipoprotein in patients with coronary atherosclerosis
    • Bui MN, Sack MN, Moutsatsos G, Lu DY, Katz P, McCown R et al. Autoantibody titers to oxidized low-density lipoprotein in patients with coronary atherosclerosis. Am Heart J 1996;131:663-7.
    • (1996) Am Heart J , vol.131 , pp. 663-667
    • Bui, M.N.1    Sack, M.N.2    Moutsatsos, G.3    Lu, D.Y.4    Katz, P.5    McCown, R.6
  • 52
    • 0035281469 scopus 로고    scopus 로고
    • Clinical significance of antibody against oxidized low density lipoprotein in patients with atherosclerotic coronary artery disease
    • Inoue T, Uchida T, Kamishirado H, Takayanagi K, Hayashi T, Morooka S. Clinical significance of antibody against oxidized low density lipoprotein in patients with atherosclerotic coronary artery disease. J Am Coll Cardiol 2001;37:775-9.
    • (2001) J Am Coll Cardiol , vol.37 , pp. 775-779
    • Inoue, T.1    Uchida, T.2    Kamishirado, H.3    Takayanagi, K.4    Hayashi, T.5    Morooka, S.6
  • 53
    • 0032920559 scopus 로고    scopus 로고
    • Autoantibodies against oxidized low density lipoprotein in patients with angiographically verified coronary artery disease
    • Lehtimaki T, Lehtinen S, Solakivi T, Nikkila M, Jaakkola O, Jokela H et al. Autoantibodies against oxidized low density lipoprotein in patients with angiographically verified coronary artery disease. Arterioscler Thromb Vasc Biol 1999;19:23-7.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 23-27
    • Lehtimaki, T.1    Lehtinen, S.2    Solakivi, T.3    Nikkila, M.4    Jaakkola, O.5    Jokela, H.6
  • 55
    • 0034700233 scopus 로고    scopus 로고
    • Circulating Immune Complexes in 50-Year-Old Men as a Strong and Independent Risk Factor for Myocardial Infarction
    • Mustafa A, Nityanand S, Berglund L, Lithell H, Lefvert AK. Circulating Immune Complexes in 50-Year-Old Men as a Strong and Independent Risk Factor for Myocardial Infarction. Circulation 2000;102:2576-81.
    • (2000) Circulation , vol.102 , pp. 2576-2581
    • Mustafa, A.1    Nityanand, S.2    Berglund, L.3    Lithell, H.4    Lefvert, A.K.5
  • 56
    • 0031459413 scopus 로고    scopus 로고
    • Antibodies against cardiolipin and oxidatively modified LDL in 50-year-old men predict myocardial infarction
    • Wu R, Nityanand S, Berglund L, Lithell H, Holm G, Lefvert AK. Antibodies against cardiolipin and oxidatively modified LDL in 50-year-old men predict myocardial infarction. Arterioscler Thromb Vasc Biol 1997;17:3159-63.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 3159-3163
    • Wu, R.1    Nityanand, S.2    Berglund, L.3    Lithell, H.4    Holm, G.5    Lefvert, A.K.6
  • 57
  • 58
    • 0029003223 scopus 로고
    • Detection of autoantibodies against oxidized low-density lipoproteins and of IgG-bound low density lipoproteins in patients with coronary artery disease
    • Bouffier A, Hamon M, Walters-Laporte E, Martin-Nizart F, Mackereel R, Fruchart JC et al. Detection of autoantibodies against oxidized low-density lipoproteins and of IgG-bound low density lipoproteins in patients with coronary artery disease. Clin Chim Acta 1995;238:1-10.
    • (1995) Clin Chim Acta , vol.238 , pp. 1-10
    • Bouffier, A.1    Hamon, M.2    Walters-Laporte, E.3    Martin-Nizart, F.4    Mackereel, R.5    Fruchart, J.C.6
  • 59
    • 0344825223 scopus 로고    scopus 로고
    • Antibodies to oxidized Low-Density Lipoproteins and angiographically assessed coronary artery disease in white patients
    • Rossi GP, Cesari M, De Toni R, Zanchetta M, Maiolino G, Pedon L et al. Antibodies to oxidized Low-Density Lipoproteins and angiographically assessed coronary artery disease in white patients. Circulation 2003;108:2467-72.
    • (2003) Circulation , vol.108 , pp. 2467-2472
    • Rossi, G.P.1    Cesari, M.2    De Toni, R.3    Zanchetta, M.4    Maiolino, G.5    Pedon, L.6
  • 60
    • 0029819268 scopus 로고    scopus 로고
    • Autoantibodies against oxidized LDL do not predict atherosclerotic vascular disease in non-insulin-dependent diabetes mellitus
    • Uusitupa MI, Niskanen L, Luoma J, Vilja P, Mercuri M, Rauramaa R et al. Autoantibodies against oxidized LDL do not predict atherosclerotic vascular disease in non-insulin-dependent diabetes mellitus. Arterioscler Thromb Vasc Biol 1996;16:1236-42.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 1236-1242
    • Uusitupa, M.I.1    Niskanen, L.2    Luoma, J.3    Vilja, P.4    Mercuri, M.5    Rauramaa, R.6
  • 63
    • 0028170614 scopus 로고
    • LDL oxidation in patients with severe carotid atherosclerosis. A study of in vitro and in vivo oxidation markers
    • Maggi E, Chiesa R, Melissano G, Castellano R, Astore D, Grossi A et al. LDL oxidation in patients with severe carotid atherosclerosis. A study of in vitro and in vivo oxidation markers. Arterioscler Thromb 1994;14:1892-9.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1892-1899
    • Maggi, E.1    Chiesa, R.2    Melissano, G.3    Castellano, R.4    Astore, D.5    Grossi, A.6
  • 64
    • 0035151814 scopus 로고    scopus 로고
    • Antibodies to oxidized LDL in relation to intima-media thickness in carotid and femoral arteries in 58-year-old subjectively clinically healthy men
    • Hulthe J, Bokemark L, Fagerberg B. Antibodies to oxidized LDL in relation to intima-media thickness in carotid and femoral arteries in 58-year-old subjectively clinically healthy men. Arterioscler Thromb Vasc Biol 2001;21:101-7.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 101-107
    • Hulthe, J.1    Bokemark, L.2    Fagerberg, B.3
  • 66
    • 34848825887 scopus 로고    scopus 로고
    • Autoantibody against the amino acid sequence 661-680 in apo B-100 is associated with decreased carotid stenosis and cardiovascular events
    • Fredrikson GN, Schiopu A, Berglund G, Alm R, Shah PK, Nilsson J. Autoantibody against the amino acid sequence 661-680 in apo B-100 is associated with decreased carotid stenosis and cardiovascular events. Atherosclerosis 2007.
    • (2007) Atherosclerosis
    • Fredrikson, G.N.1    Schiopu, A.2    Berglund, G.3    Alm, R.4    Shah, P.K.5    Nilsson, J.6
  • 67
    • 0242381313 scopus 로고    scopus 로고
    • Immunoglobulin M type of autoantibodies to oxidized low-density lipoprotein has an inverse relation to carotid artery atherosclerosis
    • Karvonen J, Paivansalo M, Kesaniemi YA, Hörkkö S. Immunoglobulin M type of autoantibodies to oxidized low-density lipoprotein has an inverse relation to carotid artery atherosclerosis. Circulation 2003;108:2107-12.
    • (2003) Circulation , vol.108 , pp. 2107-2112
    • Karvonen, J.1    Paivansalo, M.2    Kesaniemi, Y.A.3    Hörkkö, S.4
  • 68
    • 20144378591 scopus 로고    scopus 로고
    • Humoral immune response against defined oxidized low-density lipoprotein antigens reflects structure and disease activity of carotid plaques
    • Goncalves I, Gronholdt ML, Soderberg I, Ares MPS, Nordestgaard BG, Bentzon JF et al. Humoral immune response against defined oxidized low-density lipoprotein antigens reflects structure and disease activity of carotid plaques. Arterioscler Thromb Vasc Biol 2005;25:1250-5.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1250-1255
    • Goncalves, I.1    Gronholdt, M.L.2    Soderberg, I.3    Ares, M.P.S.4    Nordestgaard, B.G.5    Bentzon, J.F.6
  • 69
    • 34247553751 scopus 로고    scopus 로고
    • Association between IgM against an aldehyde-modified peptide in apolipoprotein B-100 and progression of carotid disease
    • Fredrikson GN, Hedblad B, Berglund G, Alm R, Nilsson JA, Schiopu A et al. Association between IgM against an aldehyde-modified peptide in apolipoprotein B-100 and progression of carotid disease. Stroke 2007;38:1495-500.
    • (2007) Stroke , vol.38 , pp. 1495-1500
    • Fredrikson, G.N.1    Hedblad, B.2    Berglund, G.3    Alm, R.4    Nilsson, J.A.5    Schiopu, A.6
  • 71
    • 24744462348 scopus 로고    scopus 로고
    • Thematic review series: The Immune System and Atherogenesis. The role of natural antibodies in atherogenesis
    • Binder CJ, Shaw PX, Chang MK, Bouffier A, Hartvigsen K, Horkko S et al. Thematic review series: The Immune System and Atherogenesis. The role of natural antibodies in atherogenesis. Journal of Lipid Research 2005;46:1353-63.
    • (2005) Journal of Lipid Research , vol.46 , pp. 1353-1363
    • Binder, C.J.1    Shaw, P.X.2    Chang, M.K.3    Bouffier, A.4    Hartvigsen, K.5    Horkko, S.6
  • 73
    • 0037419857 scopus 로고    scopus 로고
    • Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes
    • Tsimikas S, Bergmark C, Beyer RW, Patel R, Pattison J, Miller E et al. Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes. J Am Coll Cardiol 2003;41:360-70.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 360-370
    • Tsimikas, S.1    Bergmark, C.2    Beyer, R.W.3    Patel, R.4    Pattison, J.5    Miller, E.6
  • 74
    • 0028914771 scopus 로고
    • Transient reduction of autoantibodies against oxidized LDL in patients with acute myocardial infarction
    • Schumacher M, Eber B, Tatzber F, Kaufmann P, Halwachs G, Fruhwald FM et al. Transient reduction of autoantibodies against oxidized LDL in patients with acute myocardial infarction. Free Radic Biol Med 1995;18:1087-91.
    • (1995) Free Radic Biol Med , vol.18 , pp. 1087-1091
    • Schumacher, M.1    Eber, B.2    Tatzber, F.3    Kaufmann, P.4    Halwachs, G.5    Fruhwald, F.M.6
  • 75
    • 4544261604 scopus 로고    scopus 로고
    • Percutaneous coronary intervention results in acute increases in oxidized phospholipids and lipoprotein(a): Short-term and long-term immunologic responses to oxidized low-density lipoprotein
    • Tsimikas S, Lau HK, Han KR, Shortal B, Miller ER, Segev A et al. Percutaneous coronary intervention results in acute increases in oxidized phospholipids and lipoprotein(a): Short-term and long-term immunologic responses to oxidized low-density lipoprotein. Circulation 2004;109:3164-70.
    • (2004) Circulation , vol.109 , pp. 3164-3170
    • Tsimikas, S.1    Lau, H.K.2    Han, K.R.3    Shortal, B.4    Miller, E.R.5    Segev, A.6
  • 76
    • 0036211605 scopus 로고    scopus 로고
    • The effects of lipid-lowering therapy on low-density lipoprotein auto-antibodies: Relationship with low-density lipoprotein oxidation and plasma total antioxidant status
    • Orem C, Orem A, Uydu HA, Celik S, Erdol C, Kural BV. The effects of lipid-lowering therapy on low-density lipoprotein auto-antibodies: relationship with low-density lipoprotein oxidation and plasma total antioxidant status. Coron Artery Dis 2002;13:65-71.
    • (2002) Coron Artery Dis , vol.13 , pp. 65-71
    • Orem, C.1    Orem, A.2    Uydu, H.A.3    Celik, S.4    Erdol, C.5    Kural, B.V.6
  • 77
    • 33644891902 scopus 로고    scopus 로고
    • Reduction of oxidative stress and modulation of autoantibodies against modified low-density lipoprotein after rosuvastatin therapy
    • Resch U, Tatzber F, Budinsky A, Sinzinger H. Reduction of oxidative stress and modulation of autoantibodies against modified low-density lipoprotein after rosuvastatin therapy. British Journal of Clinical Pharmacology 2006;61:262-74.
    • (2006) British Journal of Clinical Pharmacology , vol.61 , pp. 262-274
    • Resch, U.1    Tatzber, F.2    Budinsky, A.3    Sinzinger, H.4
  • 78
    • 16344379409 scopus 로고    scopus 로고
    • Natural antibodies and the autoimmunity of atherosclerosis
    • Binder CJ, Silverman GJ. Natural antibodies and the autoimmunity of atherosclerosis. Springer Semin Immunopathol 2005;26:385-404.
    • (2005) Springer Semin Immunopathol , vol.26 , pp. 385-404
    • Binder, C.J.1    Silverman, G.J.2
  • 79
    • 16344380083 scopus 로고    scopus 로고
    • Inherent specificities in natural antibodies: A key to immune defense against pathogen invasion
    • Baumgarth N, Tung JW, Herzenberg LA. Inherent specificities in natural antibodies: a key to immune defense against pathogen invasion. Springer Semin Immunopathol 2005;26:347-62.
    • (2005) Springer Semin Immunopathol , vol.26 , pp. 347-362
    • Baumgarth, N.1    Tung, J.W.2    Herzenberg, L.A.3
  • 80
    • 33847343450 scopus 로고    scopus 로고
    • Newborn humans manifest autoantibodies to defined self molecules detected by antigen microarray informatics
    • Merbl Y, Zucker-Toledano M, Quintana FJ, Cohen IR. Newborn humans manifest autoantibodies to defined self molecules detected by antigen microarray informatics. J Clin Invest 2007;117:712-8.
    • (2007) J Clin Invest , vol.117 , pp. 712-718
    • Merbl, Y.1    Zucker-Toledano, M.2    Quintana, F.J.3    Cohen, I.R.4
  • 82
    • 0142055950 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS
    • Griendling KK, FitzGerald GA. Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS. Circulation 2003;108:1912-6.
    • (2003) Circulation , vol.108 , pp. 1912-1916
    • Griendling, K.K.1    FitzGerald, G.A.2
  • 83
    • 0242349764 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular injury: Part II: animal and human studies
    • Griendling KK, FitzGerald GA. Oxidative stress and cardiovascular injury: Part II: animal and human studies. Circulation 2003;108:2034-40.
    • (2003) Circulation , vol.108 , pp. 2034-2040
    • Griendling, K.K.1    FitzGerald, G.A.2
  • 84
    • 0036847364 scopus 로고    scopus 로고
    • B-lymphocyte deficiency increases atherosclerosis in LDL receptor-null mice
    • Major AS, Fazio S, Linton MF. B-lymphocyte deficiency increases atherosclerosis in LDL receptor-null mice. Arterioscler Thromb Vasc Biol 2002;22:1892-8.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1892-1898
    • Major, A.S.1    Fazio, S.2    Linton, M.F.3
  • 85
    • 0036193513 scopus 로고    scopus 로고
    • Protective immunity against atherosclerosis carried by B cells of hypercholesterolemic mice
    • Caligiuri G, Nicoletti A, Poirier B, Hansson GK. Protective immunity against atherosclerosis carried by B cells of hypercholesterolemic mice. J Clin Invest 2002;109:745-53.
    • (2002) J Clin Invest , vol.109 , pp. 745-753
    • Caligiuri, G.1    Nicoletti, A.2    Poirier, B.3    Hansson, G.K.4
  • 86
    • 0032989435 scopus 로고    scopus 로고
    • Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: Evidence that oxidation-specific epitopes mediate macrophage recognition
    • Chang MK, Bergmark C, Laurila A, Hörkkö S, Han KH, Friedman P et al. Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: evidence that oxidation-specific epitopes mediate macrophage recognition. Proc Natl Acad Sci U S A 1999;96:6353-8.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 6353-6358
    • Chang, M.K.1    Bergmark, C.2    Laurila, A.3    Hörkkö, S.4    Han, K.H.5    Friedman, P.6
  • 87
    • 0036791022 scopus 로고    scopus 로고
    • C-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: Phosphorylcholine of oxidized phospholipids
    • Chang MK, Binder CJ, Torzewski M, Witztum JL. C-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: Phosphorylcholine of oxidized phospholipids. Proc Nad Acad Sci U S A 2002;99:13043-8.
    • (2002) Proc Nad Acad Sci U S A , vol.99 , pp. 13043-13048
    • Chang, M.K.1    Binder, C.J.2    Torzewski, M.3    Witztum, J.L.4
  • 89
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005;352:1685-95.
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 92
    • 0037896283 scopus 로고    scopus 로고
    • Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins
    • Horkko S, Bird DA, Miller E, Itabe H, Leitinger N, Subbanagounder G et al. Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins. J Clin Invest 1999;103:117-28.
    • (1999) J Clin Invest , vol.103 , pp. 117-128
    • Horkko, S.1    Bird, D.A.2    Miller, E.3    Itabe, H.4    Leitinger, N.5    Subbanagounder, G.6
  • 93
    • 0029957467 scopus 로고    scopus 로고
    • Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma
    • Palinski W, Hörkkö S, Miller E, Steinbrecher UP, Powell HC, Curtiss LK et al. Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma. J Clin Invest 1996;98:800-14.
    • (1996) J Clin Invest , vol.98 , pp. 800-814
    • Palinski, W.1    Hörkkö, S.2    Miller, E.3    Steinbrecher, U.P.4    Powell, H.C.5    Curtiss, L.K.6
  • 94
    • 0342939538 scopus 로고    scopus 로고
    • Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity
    • Shaw PX, Hörkkö S, Chang MK, Curtiss LK, Palinski W, Silverman GJ et al. Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity. J Clin Invest 2000;105:1731-40.
    • (2000) J Clin Invest , vol.105 , pp. 1731-1740
    • Shaw, P.X.1    Hörkkö, S.2    Chang, M.K.3    Curtiss, L.K.4    Palinski, W.5    Silverman, G.J.6
  • 95
    • 0019972628 scopus 로고
    • Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae
    • Briles DE, Forman C, Hudak S, Claflin JL. Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae. J Exp Med 1982;156:1177-85.
    • (1982) J Exp Med , vol.156 , pp. 1177-1185
    • Briles, D.E.1    Forman, C.2    Hudak, S.3    Claflin, J.L.4
  • 96
    • 0037163149 scopus 로고    scopus 로고
    • Innate and adaptive immunity in the pathogenesis of atherosclerosis
    • Hansson GK, Libby P, Schonbeck U, Yan ZQ. Innate and adaptive immunity in the pathogenesis of atherosclerosis. Circ Res 2002;91:281-91.
    • (2002) Circ Res , vol.91 , pp. 281-291
    • Hansson, G.K.1    Libby, P.2    Schonbeck, U.3    Yan, Z.Q.4
  • 97
    • 0038375997 scopus 로고    scopus 로고
    • Pneumococcal vaccination decreases atherosclerotic lesion formation: Molecular mimicry between Streptococcus pneumoniae and oxidized LDL
    • Binder CJ, Horkko S, Dewan A, Chang MK, Kieu EP, Goodyear CS et al. Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL. Nat Med 2003;9:736-43.
    • (2003) Nat Med , vol.9 , pp. 736-743
    • Binder, C.J.1    Horkko, S.2    Dewan, A.3    Chang, M.K.4    Kieu, E.P.5    Goodyear, C.S.6
  • 98
    • 0026683392 scopus 로고
    • Induction of arteriosclerosis in normocholesterolemic rabbits by immunization with heat shock protein 65
    • Xu Q, Dietrich H, Steiner HJ, Gown AM, Schoel B, Mikuz G et al. Induction of arteriosclerosis in normocholesterolemic rabbits by immunization with heat shock protein 65. Arterioscler Thromb 1992;12:789-99.
    • (1992) Arterioscler Thromb , vol.12 , pp. 789-799
    • Xu, Q.1    Dietrich, H.2    Steiner, H.J.3    Gown, A.M.4    Schoel, B.5    Mikuz, G.6
  • 99
    • 33744997165 scopus 로고    scopus 로고
    • Monoclonal antibodies: Production, uses and side effects
    • Cowden J, Parker SK. Monoclonal antibodies: production, uses and side effects. Pediatr Infect Dis J 2006;25:553-5.
    • (2006) Pediatr Infect Dis J , vol.25 , pp. 553-555
    • Cowden, J.1    Parker, S.K.2
  • 100
    • 0028895573 scopus 로고
    • Immunization of LDL receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis
    • Palinski W, Miller E, Witztum JL. Immunization of LDL receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis. Proc Natl Acad Sci USA 1995;92:821-5.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 821-825
    • Palinski, W.1    Miller, E.2    Witztum, J.L.3
  • 101
    • 0031541903 scopus 로고    scopus 로고
    • Immunization with homologous oxidized low density lipoprotein reduces neointimal formation after balloon injury in hypercholesterolemic rabbits
    • Nilsson J, Calara F, Regnstrom J, Hultgardh-Nilsson A, Ameli S, Cercek B et al. Immunization with homologous oxidized low density lipoprotein reduces neointimal formation after balloon injury in hypercholesterolemic rabbits. J Am Coll Cardiol 1997;30:1886-91.
    • (1997) J Am Coll Cardiol , vol.30 , pp. 1886-1891
    • Nilsson, J.1    Calara, F.2    Regnstrom, J.3    Hultgardh-Nilsson, A.4    Ameli, S.5    Cercek, B.6
  • 102
    • 0031702543 scopus 로고    scopus 로고
    • Immunization of LDL receptor-deficient mice with homologous malondialdehyde- modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes
    • Freigang S, Hörkkö S, Miller E, Witztum JL, Palinski W. Immunization of LDL receptor-deficient mice with homologous malondialdehyde- modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes. Arterioscler Thromb Vasc Biol 1998;18:1972-82.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1972-1982
    • Freigang, S.1    Hörkkö, S.2    Miller, E.3    Witztum, J.L.4    Palinski, W.5
  • 103
    • 0035170994 scopus 로고    scopus 로고
    • Zhou X, Caligiuri G, Hamsten A, Lefvert AK, Hansson GK. LDL Immunization Induces T-Cell-Dependent Antibody Formation and Protection Against Atherosclerosis. Arterioscler Thromb Vasc Biol 2001;21:108-14.
    • Zhou X, Caligiuri G, Hamsten A, Lefvert AK, Hansson GK. LDL Immunization Induces T-Cell-Dependent Antibody Formation and Protection Against Atherosclerosis. Arterioscler Thromb Vasc Biol 2001;21:108-14.
  • 104
    • 0029793720 scopus 로고    scopus 로고
    • Effect of immunization with homologous LDL and oxidized LDL on early atherosclerosis in hypercholesterolemic rabbits
    • Ameli S, Hultgardh-Nilsson A, Regnstrom J, Calara F, Yano J, Cercek B et al. Effect of immunization with homologous LDL and oxidized LDL on early atherosclerosis in hypercholesterolemic rabbits. Arterioscler Thromb Vasc Biol 1996;16:1074-9.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 1074-1079
    • Ameli, S.1    Hultgardh-Nilsson, A.2    Regnstrom, J.3    Calara, F.4    Yano, J.5    Cercek, B.6
  • 105
    • 4043152981 scopus 로고    scopus 로고
    • IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis
    • Binder CJ, Hartvigsen K, Chang MK, Miller M, Broide D, Palinski W et al. IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis. J Clin Invest 2004;114:427-37.
    • (2004) J Clin Invest , vol.114 , pp. 427-437
    • Binder, C.J.1    Hartvigsen, K.2    Chang, M.K.3    Miller, M.4    Broide, D.5    Palinski, W.6
  • 108
    • 27844435115 scopus 로고    scopus 로고
    • Immunization using an Apo B-100 related epitope reduces atherosclerosis and plaque inflammation in hypercholesterolemic apo E (-/-) mice
    • Chyu KY, Zhao X, Reyes OS, Babbidge SM, Dimayuga PC, Yano J et al. Immunization using an Apo B-100 related epitope reduces atherosclerosis and plaque inflammation in hypercholesterolemic apo E (-/-) mice. Biochem Biophys Res Commun 2005;338:1982-9.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 1982-1989
    • Chyu, K.Y.1    Zhao, X.2    Reyes, O.S.3    Babbidge, S.M.4    Dimayuga, P.C.5    Yano, J.6
  • 109
    • 34250319739 scopus 로고    scopus 로고
    • Autoimmune responses against the apo B-100 LDL receptor-binding site protect against arterial accumulation of lipids in LDL receptor deficient mice
    • Fredrikson GN, Lindholm MW, Ljungcrantz I, Soderberg I, Shah PK, Nilsson J. Autoimmune responses against the apo B-100 LDL receptor-binding site protect against arterial accumulation of lipids in LDL receptor deficient mice. Autoimmunity 2007;40:122-30.
    • (2007) Autoimmunity , vol.40 , pp. 122-130
    • Fredrikson, G.N.1    Lindholm, M.W.2    Ljungcrantz, I.3    Soderberg, I.4    Shah, P.K.5    Nilsson, J.6
  • 112
    • 0142103926 scopus 로고    scopus 로고
    • Reduction of atherosclerosis in low-density lipoprotein receptor-deficient mice by passive administration of antiphospholipid antibody
    • Nicolo D, Goldman BI, Monestier M. Reduction of atherosclerosis in low-density lipoprotein receptor-deficient mice by passive administration of antiphospholipid antibody. Arthritis Rheum 2003;48:2974-8.
    • (2003) Arthritis Rheum , vol.48 , pp. 2974-2978
    • Nicolo, D.1    Goldman, B.I.2    Monestier, M.3
  • 113
    • 20844432027 scopus 로고    scopus 로고
    • Recombinant human antibodies against aldehyde-modified apolipoprotein B-100 peptide sequences inhibit atherosclerosis
    • Schiopu A, Bengtsson J, Soderberg I, Janciauskiene S, Lindgren S, Ares MP et al. Recombinant human antibodies against aldehyde-modified apolipoprotein B-100 peptide sequences inhibit atherosclerosis. Circulation 2004;110:2047-52.
    • (2004) Circulation , vol.110 , pp. 2047-2052
    • Schiopu, A.1    Bengtsson, J.2    Soderberg, I.3    Janciauskiene, S.4    Lindgren, S.5    Ares, M.P.6
  • 114
    • 33846064690 scopus 로고    scopus 로고
    • Inhibition of injury-induced arterial remodelling and carotid atherosclerosis by recombinant human antibodies against aldehyde-modified apoB-100
    • Strom A, Fredrikson GN, Schiopu A, Ljungcrantz I, Soderberg I, Jansson B et al. Inhibition of injury-induced arterial remodelling and carotid atherosclerosis by recombinant human antibodies against aldehyde-modified apoB-100. Atherosclerosis 2007;190:298-305.
    • (2007) Atherosclerosis , vol.190 , pp. 298-305
    • Strom, A.1    Fredrikson, G.N.2    Schiopu, A.3    Ljungcrantz, I.4    Soderberg, I.5    Jansson, B.6
  • 115
    • 33749147435 scopus 로고    scopus 로고
    • Passive immunization with monoclonal IgM antibodies against phosphorylcholine reduces accelerated vein graft atherosclerosis in apolipoprotein Å-null mice
    • Faria-Neto JR, Chyu KY, Li X, Dimayuga PC, Ferreira C, Yano J et al. Passive immunization with monoclonal IgM antibodies against phosphorylcholine reduces accelerated vein graft atherosclerosis in apolipoprotein Å-null mice. Atherosclerosis 2006;189: 83-90.
    • (2006) Atherosclerosis , vol.189 , pp. 83-90
    • Faria-Neto, J.R.1    Chyu, K.Y.2    Li, X.3    Dimayuga, P.C.4    Ferreira, C.5    Yano, J.6
  • 116
    • 0035573706 scopus 로고    scopus 로고
    • Human-derived anti-oxidized LDL autoantibody blocks uptake of oxidized LDL by macrophages and localizes to atherosclerotic lesions in vivo
    • Shaw PX, Hörkkö S, Tsimikas S, Chang MK, Palinski W, Silverman GJ et al. Human-derived anti-oxidized LDL autoantibody blocks uptake of oxidized LDL by macrophages and localizes to atherosclerotic lesions in vivo. Arterioscler Thromb Vasc Biol 2001;21:1333-9.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1333-1339
    • Shaw, P.X.1    Hörkkö, S.2    Tsimikas, S.3    Chang, M.K.4    Palinski, W.5    Silverman, G.J.6
  • 118
    • 4444236665 scopus 로고    scopus 로고
    • Antibodies to oxidized LDL in atherosclerosis development - clinical and animal studies
    • Hulthe J. Antibodies to oxidized LDL in atherosclerosis development - clinical and animal studies. Clinica Chimica Acta 2004;348:1-8.
    • (2004) Clinica Chimica Acta , vol.348 , pp. 1-8
    • Hulthe, J.1
  • 119
    • 7544229779 scopus 로고    scopus 로고
    • Are antioxidized Low-Density Lipoprotein antibodies pathogenic or protective?
    • Shoenfeld Y, Wu R, Dearing LD, Matsuura E. Are antioxidized Low-Density Lipoprotein antibodies pathogenic or protective? Circulation 2004;110:2552-8.
    • (2004) Circulation , vol.110 , pp. 2552-2558
    • Shoenfeld, Y.1    Wu, R.2    Dearing, L.D.3    Matsuura, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.