Studies on quinones. Part 42: Synthesis of furylquinone and hydroquinones with antiproliferative activity against human tumor cell lines

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 2, 2008, Pages 862-868

  Benites, Julio ^a   Valderrama, Jaime A ^b   Rivera, Felipe ^b   Rojo, Leonel ^a   Campos, Nair ^c   Pedro, Madalena ^c   José Nascimento, María Säo ^c  

^a UNIVERSIDAD ARTURO PRAT   (Chile)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^c UNIVERSITY OF PORTO   (Portugal)

Author keywords

Cytotoxicity; Michael addition; Oxidative coupling; Quinones

Indexed keywords

2 (5 N,N DIMETHYLHYDRAZONOFUR 2 YL) 1,4 BENZOQUINONE; 2 (5 N,N DIMETHYLHYDRAZONOFUR 2 YL) 1,4 NAPHTHOQUINONE; 3 CHLORO 2 (5 N,N DIMETHYLHYDRAZONOFUR 2 YL) 1,4 NAPHTHOQUINONE; ANTINEOPLASTIC AGENT; DOXORUBICIN; HYDRAZONE DERIVATIVE; HYDROQUINONE DERIVATIVE; QUINONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; OXIDATION; REACTION ANALYSIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; HYDROQUINONES; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; QUINONES;

EID: 38549171048     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.10.028     Document Type: Article

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