Studies on quinones. Part 41: Synthesis and cytotoxicity of isoquinoline-containing polycyclic quinones

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 14, 2006, Pages 5003-5011

  Valderrama, Jaime A ^a   González, M Florencia ^a   Pessoa Mahana, David ^a   Tapia, Ricardo A ^a   Fillion, Houda ^b   Pautet, Felix ^b   Rodriguez, Jaime A ^c   Theoduloz, Cristina ^c   Schmeda Hirschmann, Guillermo ^c  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b UNIVERSITÉ LYON 1   (France)

^c UNIVERSIDAD DE TALCA   (Chile)

Author keywords

Aza anthraquinones; Cytotoxicity; Diels Alder reaction; Regioselectivity

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOXYLIC ACID; ISOQUINOLINE; METHYL 1,3 DIMETHYL 5,8 DIOXO 5,8 DIHYDROISOQUINOLONE 4 CARBOXYLATE; POLYCYCLIC HYDROCARBON; QUINONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CYCLOADDITION; CYTOTOXICITY; DIELS ALDER REACTION; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS;

ANTINEOPLASTIC AGENTS; CELL LINE; CELL LINE, TUMOR; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; ETOPOSIDE; FIBROBLASTS; HUMANS; QUINONES;

EID: 33646791155     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.03.008     Document Type: Article

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