A membrane-bound form of IL-4 enhances proliferation and antigen presentation of CD40-activated human B cells

Immunology Letters

Volumn 116, Issue 1, 2008, Pages 33-40

  Park, Jung Yong ^a   Yoon, Sung Hee ^a   Kim, Eun Kyung ^a   Yun, Sun Ok ^a   Park, Mi Young ^a   Sohn, Hyun Jung ^a   Kim, Tai Gyu ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Antigen presenting cell; B cell; CD40L; Membrane bound IL 4

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; INTERLEUKIN 4; PP65 ANTIGEN; UNCLASSIFIED DRUG; VIRUS ANTIGEN;

ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; CELL ADHESION; CELL PROLIFERATION; CELL STRAIN K 562; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOMETRY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; FLUORESCENCE ACTIVATED CELL SORTING; HLA SYSTEM; HUMAN; HUMAN CELL; IN VITRO STUDY; NORMAL HUMAN; PHENOTYPE; PLASMA CELL; PRIORITY JOURNAL;

ANTIGEN PRESENTATION; ANTIGENS, CD40; ANTIGENS, VIRAL; B-LYMPHOCYTES; CD40 LIGAND; CELL MEMBRANE; CELL PROLIFERATION; HUMANS; INTERLEUKIN-4; K562 CELLS; LYMPHOCYTE ACTIVATION; PHOSPHOPROTEINS; RECOMBINANT PROTEINS; TRANSFECTION; VIRAL MATRIX PROTEINS;

EID: 38549120172     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2007.11.005     Document Type: Article

References (43)

1. Steinman R.M., Witmer-Pack M., and Inaba K. Dendritic cells: antigen presentation, accessory function and clinical relevance. Adv Exp Med Biol 329 (1993) 1-9
2. von Bergwelt-Baildon M.S., Vonderheide R.H., Maecker B., Hirano N., Anderson K.S., Butler M.O., et al. Human primary and memory cytotoxic T lymphocyte responses are efficiently induced by means of CD40-activated B cells as antigen-presenting cells: potential for clinical application. Blood 99 9 (2002) 3319-3325
3. Thurner B., Haendle I., Roder C., Dieckmann D., Keikavoussi P., Jonuleit H., et al. Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma. J Exp Med 190 11 (1999) 1669-1678
4. Heiser A., Coleman D., Dannull J., Yancey D., Maurice M.A., Lallas C.D., et al. Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors. J Clin Invest 109 3 (2002) 409-417
5. Maier T., Tun-Kyi A., Tassis A., Jungius K.P., Burg G., Dummer R., et al. Vaccination of patients with cutaneous T-cell lymphoma using intranodal injection of autologous tumor-lysate-pulsed dendritic cells. Blood 102 7 (2003) 2338-2344
6. Kugler A., Stuhler G., Walden P., Zoller G., Zobywalski A., Brossart P., et al. Regression of human metastatic renal cell carcinoma after vaccination with tumor cell-dendritic cell hybrids. Nat Med 6 3 (2000) 332-336
7. Schultze J.L., Michalak S., Seamon M.J., Dranoff G., Jung K., Daley J., et al. CD40-activated human B cells: an alternative source of highly efficient antigen presenting cells to generate autologous antigen-specific T cells for adoptive immunotherapy. J Clin Invest 100 11 (1997) 2757-2765
8. Kondo E., Topp M.S., Kiem H.P., Obata Y., Morishima Y., Kuzushima K., et al. Efficient generation of antigen-Specific cytotoxic T cells using retrovirally transduced CD40-activated B cells. J Immunol 169 4 (2002) 2164-2171
9. Schultze J.L., Grabbe S., and von Bergwelt-Baildon M.S. DCs and CD40-activated B cells: current and future avenues to cellular cancer immunotherapy. Trends Immunol 25 12 (2004) 659-664
10. Coughlin C.M., Vance B.A., Grupp S.A., and Vonderheide R.H. RNA-transfected CD40-activated B cells induce functional T-cell responses against viral and tumor antigen targets: implications for pediatric immunotherapy. Blood 103 6 (2004) 2046-2054
11. Grewal I.S., and Flavell R.A. CD40 and CD154 in cell-mediated immuity. Annu Rev Immunol 16 (1998) 111-135
12. Ivanov R., Aarts T., Hagenbeek A., Hol S., and Ebeling S. B-cell expansion in the presence of the novel 293-CD40L-sCD40L cell line allows the generation of large numbers of efficient xenoantigen-free APC. Cytotherapy 7 1 (2005) 62-73
13. Yoon S.H., Cho H.I., and Kim T.G. Activation of B cells using Schneider 2 cells expressing CD40 ligand for the enhancement of antigen presentation in vitro. Exp Mol Med 37 6 (2005) 567-574
14. Maus M.V., Thomas A.K., Leonard D.G., Allman D., Addya K., Schlienger K., et al. Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB. Nat Biotechnol 20 2 (2002) 143-148
15. Itoh K., and Hirohata S. The role of IL-10 in human B cell activation, proliferation, and differentiation. J Immunol 154 9 (1995) 4341-4350
16. Vazquez A., Mills S., and Maizel A. Modulation of IL-2-induced human B cell proliferation in the presence of human 50-kDa B cell growth factor and IL-4. J Immunol 142 1 (1989) 94-99
17. Vallé A., Zuber C.E., Defrance T., Djossou O., De Rie M., and Banchereau J. Activation of human B lymphocytes through CD40 and interleukin 4. Eur J Immunol 19 8 (1989) 1463-1467
18. Armitage R.J., Macduff B.M., Spriggs M.K., and Fanslow W.C. Human B cell proliferation and lg secretion induced by recombinant CD40 Ligand are modulated by soluble cytokines. J Immunol 150 9 (1993) 3671-3680
19. Hudak S.A., Gollnick S.O., Conrad D.H., and Kehry M.R. Murine B-cell stimulatory factor 1 (interleukin 4) increases expression of the Fc receptor for IgE on mouse B cells. Proc Natl Acad Sci USA 84 13 (1987) 4606-4610
20. Hodgkin P.D., Go N.F., Cupp J.E., and Howard M. Interleukin-4 enhances anti-IgM stimulation of B cells by improving cell viability and by increasing the sensitivity of B cells to the anti-IgM signal. Cell Immunol 134 1 (1991) 14-30
21. Chakrabarti R., Chang Y., Song K., and Prud'homme G.J. Plasmids encoding membrane-bound IL-4 or IL-12 strongly costimulate DNA vaccination against carcinoembryonic antigen (CEA). Vaccine 22 9-10 (2004) 1199-1205
22. Delon J., and Germain R.N. Information transfer at the immunological synapse. Curr Biol 10 24 (2000) 14-28
23. Kim Y.S., Sonn C.H., Paik S.G., and Bothwell A.L. Tumor cells expressing membrane-bound form of IL-4 induce antitumor immunity. Gene Ther 7 10 (2000) 837-843
24. Park C.S., Yoon S.O., Armitage R.J., and Choi Y.S. Follicular dendritic cells produce IL-15 that enhances germinal center B cell proliferation in membrane-bound form. J Immunol 173 11 (2004) 6676-6683
25. Vonderheide R.H., Hahn W.C., Schultze J.L., and Nadler L.M. The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes. Immunity 10 6 (1999) 673-679
26. Ascher N.L. Issues in xenotransplantation. Liver Transpl Surg 1 5 (1995) 320-321
27. Dessureault S., Alsarraj M., McCarthy S., Hunter T., Noyes D., Lee D., et al. A GM-CSF/CD40L producing cell augments anti-tumor T cell responses. J Surg Res 125 2 (2005) 173-181
28. Jego G., Bataille R., and Pellat-Deceunynck C. Interleukin-6 is a growth factor for nonmalignant human plasmablasts. Blood 97 6 (2001) 1817-1822
29. O'Nions J., and Allday M.J. Proliferation and differentiation in isogenic populations of peripheral B cells activated by Epstein-Barr virus or T cell-derived mitogens. J Gen Virol 85 Pt 4 (2004) 881-895
30. Fuchs E.J., and Matzinger P. B cells turn off virgin but not memory T cells. Science 258 5085 (1992) 1156-1159
31. + T cells. J Exp Med 188 11 (1998) 1977-1983
32. Lutz M.B., and Schuler G. Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?. Trends Immunol 23 9 (2002) 445-449
33. Buhlmann J.E., Foy T.M., Aruffo A., Crassi K.M., Ledbetter J.A., Green W.R., et al. In the absence of a CD40 signal, B cells are tolerogenic. Immunity 2 6 (1995) 645-653
34. Evans D.E., Munks M.W., Purkerson J.M., and Parker D.C. Resting B lymphocytes as APC for naive T lymphocytes: dependence on CD40 Ligand/CD40. J Immunol 164 2 (2000) 4688-4697
35. Faassen A.E., Dalke D.P., Berton M.T., Warren W.D., and Pierce S.K. CD40-CD40 ligand interactions stimulate B cell antigen processing. Eur J Immunol 25 12 (1995) 3249-3255
36. Banchereau J., de Paoli P., Valle A., Garcia E., and Rousset F. Long-term human B cell lines dependent on interleukin-4 and antibody to CD40. Science 251 4989 (1991) 70-72
37. Hart D.N. Dendritic Cells: unique leukocyte populations which control the primary immune response. Blood 90 9 (1997) 3245-3287
38. Banchereau J., Briere F., Caux C., Davoust J., Lebecque S., Liu Y.J., et al. Immunobiology of dendritic cells. Annu Rev Immunol 18 (2000) 767-811
39. Cochran J.R., Aivazian D., Cameron T.O., and Stern L.J. Receptor clustering and transmembrane signaling in T cells. Trends Biochem Sci 26 5 (2001) 304-310
40. Monks C.R., Freiberg B.A., Kupfer H., Sciaky N., and Kupfer A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395 6697 (1998) 82-86
41. Germain R.N. T-cell signaling: the importance of receptor clustering. Curr Biol 7 10 (1997) 640-644
42. Mohty M., Isnardon D., Charbonnier A., Lafage-Pochitaloff M., Merlin M., Sainty D., et al. Generation of potent T(h)1 responses from patients with lymphoid malignancies after differentiation of B lymphocytes into dendritic-like cells. Int Immunol 14 7 (2002) 741-750
43. Roth R., and Mamula M.J. Trafficking of adoptively transferred B lymphocytes in B-lymphocyte-deficient mice. J Exp Biol 200 Pt 14 (1997) 2057-2062